P. Germain

发表

Ethanol production by anaerobic thermophilic bacteria: regulation of lactate dehydrogenase activity in Clostridium thermohydrosulfuricum

P. Germain, F. Toukourou, L. Donaduzzi, 1986, Applied Microbiology and Biotechnology.

International Union of Pharmacology. LX. Retinoic Acid Receptors

G. Eichele, P. Chambon, R. Lotan, 2006, Pharmacological Reviews.

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications.

H. Gronemeyer, W. Bourguet, P. Germain, 2000, Trends in pharmacological sciences.

Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression.

Alessandro Barducci, Nathalie Sibille, Pau Bernadó, 2019, Structure.

Structural insights into the cooperative interaction of the intrinsically disordered co-activator TIF2 with retinoic acid receptor heterodimer (RXR/RAR)

João E. Carvalho, P. Bernadó, N. Sibille, 2020, bioRxiv.

Membrane-bound cholesterol oxidase from Rhodococcus sp. cells. Production and extraction

P. Germain, J. Kreit, G. Lefebvre, 1994 .

Intracellular pH determination of pristinamycin-producing Streptomyces pristinaespiralis by image analysis.

J. Goergen, H. Vivier, P. F. Corvini, 2000, Microbiology.

Co-regulator recruitment and the mechanism of retinoic acid receptor synergy

H. Gronemeyer, P. Germain, C. Zechel, 2002, Nature.

RARβ ligand‐binding domain bound to an SRC‐1 co‐activator peptide: purification, crystallization and preliminary X‐ray diffraction analysis

H. Gronemeyer, D. Moras, N. Rochel, 2004 .

Chemical behaviour of three radionuclides (cesium, americium and technetium) and their uptake at the cytosolic level in aquatic organisms.

P. Germain, J. Durand, J. Pieri, 1994, Biochemistry and molecular biology international.

Insights into the mechanism of the site-selective sequential palladium-catalyzed cross-coupling reactions of dibromothiophenes/dibromothiazoles and arylboronic acids. Synthesis of PPARβ/δ agonists

H. Gronemeyer, A. Lera, P. Germain, 2006 .

The ancestral retinoic acid receptor was a low-affinity sensor triggering neuronal differentiation

Jace W. Jones, P. Tomançak, V. Laudet, 2018, Science Advances.

Characterization of a chemically modified β‐amylase immobilized on porous silica

R. Crichton, P. Germain, 2007 .

Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex

A. Barducci, Loïc GrandVuillemin, W. Bourguet, 2022, bioRxiv.

Synthesis of the PPARβ/δ-selective agonist GW501516 and C4-thiazole-substituted analogs

H. Gronemeyer, A. Lera, P. Germain, 2006 .

Dimerization of nuclear receptors.

W. Bourguet, P. Germain, 2013, Methods in cell biology.

Modulating retinoid X receptor with a series of (E)-3-[4-hydroxy-3-(3-alkoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]acrylic acids and their 4-alkoxy isomers.

H. Gronemeyer, W. Bourguet, A. D. de Lera, 2009, Journal of medicinal chemistry.

Nuclear receptor ligand-binding domains: reduction of helix H12 dynamics to favour crystallization.

Efrén Pérez, W. Bourguet, A. D. de Lera, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

A colorimetric assay for measuring cell-free and cell-bound cholesterol oxidase

P. Germain, J. Kreit, G. Lefebvre, 1992, Lipids.

Extracellular cholesterol oxidase from Rhodococcus sp. cells

P. Germain, J. Kreit, G. Lefebvre, 1992 .

241Am binding-components in the digestive gland cells of the marine prosobranch Littorina littorea

P. Germain, J. Pieri, F. Goudard, 1986 .

Thermal stabilization of a chemically oriented modified pullulanase.

R. Crichton, P. Germain, J. S. Makaren, 1988, Biotechnology and bioengineering.

Ligands and DNA in the allosteric control of retinoid receptors function.

N. Rochel, W. Bourguet, P. Germain, 2021, Essays in biochemistry.

Use of confocal microscopy to localize the SHBG interaction with human breast cancer cell lines--a comparison with serum albumin interaction.

P. Germain, H. Kiefer, G. Habrioux, 1997, Cellular and molecular biology.

Influence of nutrient excess on intracellular proteins composition in relation to spiramycin production, in Streptomyces ambofaciens

P. Germain, A. Lebrihi, G. Lefebvre, 1995, Biotechnology Letters.

Catabolism of methylperhydroindanedione propionate by Rhodococcus equi: evidence of a MEPHIP-reductase activity

P. Germain, A. Miclo, 1990, Applied Microbiology and Biotechnology.

Steroid Bioconversion by Immobilized Cells

J. Engasser, P. Germain, A. Miclo, 1982 .

Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs)

Cécile Rochette-Egly, P. Germain, Pierre Germain, 2009, Nuclear receptor signaling.

A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor

H. Gronemeyer, A. Lera, C. Royer, 2010, Nature Structural &Molecular Biology.

9-cis-retinoic acid analogues with bulky hydrophobic rings: new RXR-selective agonists.

H. Gronemeyer, R. Álvarez, A. D. de Lera, 2004, Bioorganic & medicinal chemistry letters.

Identification of 137Cs‐ and 241Am‐binding sites in the oyster crassostrea gigas

P. Germain, J. Durand, J. Pieri, 1996, Biochemistry and molecular biology international.

Biodynamic study of americium-241 accumulation in the cytosol of the hepatopancreas of the lobster Homarus gammarus.

P. Germain, J. Durand, J. Pieri, 1994, Biochemistry and molecular biology international.

Relation between stabilization and rigidification of the three‐dimensional structure of an enzyme

R. Crichton, P. Germain, R R Crichton, 1989, Biotechnology and bioengineering.

Immobilization of a soluble chemically thermostabilized enzyme

R. Crichton, P. Germain, J. Lenders, 1985, Biotechnology and bioengineering.

Silicon Analogues of the Retinoid Agonists TTNPB and 3‐Methyl‐TTNPB, Disila‐TTNPB and Disila‐3‐methyl‐TTNPB: Chemistry and Biology

H. Gronemeyer, D. Moras, N. Rochel, 2007, Chembiochem : a European journal of chemical biology.

Retinoid receptor subtype-selective modulators through synthetic modifications of RARgamma agonists.

H. Gronemeyer, R. Álvarez, A. D. de Lera, 2009, Bioorganic & medicinal chemistry.

New retinoid chemotypes: 9-cis-retinoic acid analogs with hydrophobic rings derived from terpenes as selective RAR agonists.

H. Gronemeyer, R. Álvarez, A. D. de Lera, 2008, Bioorganic & medicinal chemistry.

International Union of Pharmacology. LXIII. Retinoid X Receptors

Gregor Eichele, Pierre Chambon, Reuben Lotan, 2006, Pharmacological Reviews.

Regulation of spiramycin synthesis in Streptomyces ambofaciens: effects of glucose and inorganic phosphate

P. Germain, A. Lebrihi, G. Lefebvre, 1996, Applied Microbiology and Biotechnology.

Phosphate repression of cephamycin and clavulanic acid production by Streptomyces clavuligerus

P. Germain, A. Lebrihi, G. Lefebvre, 1987, Applied Microbiology and Biotechnology.

Influence of dextrins on the assimilation of yeast extract amino acids in culture of Streptomyces ambofaciens producer of spiramycin

P. Germain, A. Lebrihi, G. Lefebvre, 1995 .

Nitrogen catabolite regulation of spiramycin production inStreptomyces ambofaciens

P. Germain, A. Lebrihi, G. Lefebvre, 1994, Current Microbiology.

Lysine catabolism inStreptomyces ambofaciens producer of macrolide antibiotic, spiramycin

P. Germain, A. Lebrihi, G. Lefebvre, 1992, Current Microbiology.

Glycerol effect on spiramycin production and valine catabolism in Streptomyces ambofaciens

P. Germain, A. Lebrihi, G. Lefebvre, 1995, Current Microbiology.

Effect of ammonium ions on spiramycin biosynthesis in Streptomyces ambofaciens

Ahmed Lebrihi, P. Germain, Pierre Germain, 1992, Applied Microbiology and Biotechnology.

Influence of short-chain fatty acids on the production of spiramycin by Streptomyces ambofaciens

F. Schneider, P. Germain, A. Lebrihi, 1992, Applied Microbiology and Biotechnology.

A study on the regulation of cephamycin C and expandase biosynthesis by Streptomyces clavuligerus in continuous and batch culture

P. Germain, A. Lebrihi, G. Lefebvre, 1988, Applied Microbiology and Biotechnology.

Carbon catabolite regulation of cephamycin C and expandase biosynthesis in Streptomyces clavuligerus

P. Germain, A. Lebrihi, G. Lefebvre, 1988, Applied Microbiology and Biotechnology.

Effect of nitrogen/carbon ratio on the specific production rate of spiramycin by Streptomyces ambofaciens

P. Germain, A. Lebrihi, G. Lefebvre, 1996 .

Influence of growth rate and precursor availability on spiramycin production in Streptomyces ambofaciens

P. Germain, A. Lebrihi, G. Lefebvre, 1995 .

A link between primary and secondary metabolism: malonyl-CoA formation in Streptomyces ambofaciens growing on ammonium ions or valine

F. Schneider, P. Germain, A. Lebrihi, 1994 .

Characterization of a secreted cholesterol oxidase from Rhodococcus sp.GKI (CIP 105335)

A. Filali-Maltouf, P. Germain, J. Boudrant, 1999 .

Intracellular pH of Streptomyces pristinaespiralis is correlated to the sequential use of carbon sources during the pristinamycins-producing process

S. Delaunay, J. Goergen, H. Vivier, 2004 .

Structure, function and modulation of retinoic acid receptor beta, a tumor suppressor.

H. Gronemeyer, R. Álvarez, A. D. de Lera, 2007, The international journal of biochemistry & cell biology.

Physiological investigations by image analysis.

M. Pons, H. Vivier, P. Germain, 1998, Journal of biotechnology.

An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist

H. Gronemeyer, W. Bourguet, V. Delfosse, 2015, PloS one.

Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function

H. Gronemeyer, C. Royer, Efrén Pérez, 2007, Proceedings of the National Academy of Sciences.

Location of respiration activity in filamentous bacteria by image analysis

H. Vivier, M. Pons, H. Vivier, 1997 .

Quantitative characterization of cellular differentiation of Streptomyces ambofaciensin submerged culture by image analysis

H. Vivier, M. Pons, H. Vivier, 1997 .

Overview of Nomenclature of Nuclear Receptors

Vincent Laudet, Catherine Dacquet, V. Laudet, 2006, Pharmacological Reviews.

IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data

Joanna L. Sharman, Pierre Germain, Michael Spedding, 2010, Nucleic Acids Res..

Nuclear receptor superfamily: Principles of signaling

Lucia Altucci, William Bourguet, Hinrich Gronemeyer, 2003 .

Topic 1 . 1 Nuclear receptor superfamily : Principles of signaling *

L. Altucci, H. Gronemeyer, W. Bourguet, 2003 .

Retinoids: potential in cancer prevention and therapy

L. Altucci, H. Gronemeyer, N. Clarke, 2004, Expert Reviews in Molecular Medicine.

Neofunctionalization in Vertebrates: The Example of Retinoic Acid Receptors

H. Gronemeyer, V. Laudet, L. Holland, 2006, PLoS genetics.

Signal Transduction and Structure of Nuclear Receptors

H. Gronemeyer, W. Bourguet, P. Germain, 2002 .

Engineered cell lines as a tool for monitoring biological activity of hormone analogs.

J. Nicolas, P. Balaguer, P. Germain, 1997, Analytical biochemistry.

Characterization of the Interaction between Retinoic Acid Receptor/Retinoid X Receptor (RAR/RXR) Heterodimers and Transcriptional Coactivators through Structural and Fluorescence Anisotropy Studies*

H. Gronemeyer, C. Royer, Efrén Pérez, 2005, Journal of Biological Chemistry.

Influence of substrate carbon on the metabolism of Clostridium thermohydrosulfuricum.

P. Germain, F. Toukourou, L. Donaduzzi, 1989, FEMS microbiology letters.

Protein-protein interactions in the regulation of RAR-RXR heterodimers transcriptional activity.

W. Bourguet, A. le Maire, P. Germain, 2020, Methods in enzymology.

Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists.

H. Gronemeyer, M. Lazar, C. Royer, 2009, Chemistry & biology.

Monitoring ligand-mediated nuclear receptor-coregulator interactions by noncovalent mass spectrometry.

H. Gronemeyer, D. Moras, A. van Dorsselaer, 2004, European journal of biochemistry.

Interplay of protein disorder in retinoic acid receptor heterodimer and its corepressor regulates gene expression

A. Barducci, P. Barthe, P. Bernadó, 2018, bioRxiv.

Structural and Functional Insights into the Ligand-binding Domain of a Nonduplicated Retinoid X Nuclear Receptor from the Invertebrate Chordate Amphioxus*

V. Laudet, D. Moras, N. Rochel, 2009, Journal of Biological Chemistry.

Rational design of RAR‐selective ligands revealed by RARβ crystal stucture

J. Starrett, H. Gronemeyer, N. Rochel, 2004, EMBO reports.

Influence of temperature and pH on production of two bacteriocins by Leuconostoc mesenteroides subsp. mesenteroides FR52 during batch fermentation

P. Germain, A. Revol-Junelles, F. Krier, 1998, Applied Microbiology and Biotechnology.

Structural insights into the interaction of the intrinsically disordered co-activator TIF2 with retinoic acid receptor heterodimer (RXR/RAR).

João E. Carvalho, P. Bernadó, N. Sibille, 2021, Journal of molecular biology.

Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations

W. Bourguet, A. le Maire, P. Balaguer, 2019, Cells.

Hexahydroindanone derivatives of steroids formed by Rhodococcus equi

P. Germain, A. Miclo, 2004, Applied Microbiology and Biotechnology.

The production of 3aα‐H‐4α‐(3′‐propionic acid)‐5α‐hydroxy‐7aβ‐methylhexahydro‐1‐indanone‐δ‐lactone by Nocardia restricta mutants

P. Germain, A. Miclo, G. Lefebvre, 1986 .

New Dithiolopyrrolone Antibiotics from Saccharothrix sp. SA 233. Part 2. Physicochemical Properties and Structure Elucidation.

P. Germain, F. Tillequin, E. Seguin, 2003 .

New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233. II. Physicochemical properties and structure elucidation.

P. Germain, F. Tillequin, E. Seguin, 2002, The Journal of antibiotics.

Regulation of valine catabolism by ammonium in Streptomyces ambofaciens, producer of spiramycin.

P. Germain, A. Lebrihi, G. Lefebvre, 1995, Canadian journal of microbiology.

Instability of glutamate production by Corynebacterium glutamicum 2262 in continuous culture using the temperature-triggered process.

D. Uy, S. Delaunay, J. Goergen, 2003, Journal of biotechnology.

C3 Halogen and C8′′ Substituents on Stilbene Arotinoids Modulate Retinoic Acid Receptor Subtype Function

H. Gronemeyer, R. Álvarez, F. Rodríguez-Barrios, 2009, ChemMedChem.

Accumulation of 241Am in subcellular structures of the hepatopancreas of the lobster Homarus gammarus

R. Paquet, R. Goudard, P. Germain, 1993 .

Modulation of Lipid Metabolism and Spiramycin Biosynthesis in Streptomyces ambofaciens Unstable Mutants

A. Dary, P. Germain, P. Leblond, 1999, Applied and Environmental Microbiology.

Pathological Interactions Between Mutant Thyroid Hormone Receptors and Corepressors and Their Modulation by a Thyroid Hormone Analogue with Therapeutic Potential.

D. Harrus, W. Bourguet, A. le Maire, 2018, Thyroid : official journal of the American Thyroid Association.

Kinetic studies on alpha-acetolactic acid extra- and intracellular oxidative decarboxylation to diacetyl by Lactococcus lactis subsp. lactis var. diacetylactis S 933 [dairy flavour]

I. Marc, P. Germain, E. Rondags, 1998 .

Quantification of extracellular α-acetolactate oxidative decarboxylation in diacetyl production by an α-acetolactate overproducing strain of Lactococcus lactis sp. lactis bv. diacetylactis

I. Marc, P. Germain, E. Rondags, 1999, Biotechnology Letters.

Use of a biotinyl-estradiol derivative to demonstrate estradiol-membrane binding sites on adherent human breast cancer MCF-7 cells.

P. Germain, M. Ratinaud, L. Tiefenauer, 1993, Anticancer research.

Relationship between valine, fatty acids, and spiramycin biosynthesis in Streptomyces ambofaciens.

F. Schneider, P. Germain, A. Lebrihi, 1994, Canadian journal of microbiology.

Direct G Protein Modulation of Cav2 Calcium Channels

B. Spiegelman, S. Kliewer, G. Eichele, 2006, Pharmacological Reviews.

Catabolism of androst‐4‐ene‐3,17‐dione by mutant strains of Nacardia restricta

P. Germain, A. Miclo, G. Lefebvre, 1986 .