Claire L Hutchings

发表

First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector–Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults

P. Klenerman, A. Leach, P. Cicconi, 2019, Clinical Infectious Diseases.

Viral vectored hepatitis C virus vaccines generate pan-genotypic T cell responses to conserved subdominant epitopes.

Leo Swadling, E. Barnes, T. Hanke, 2020, Vaccine.

Use of an Outbred Rat Hepacivirus Challenge Model for Design and Evaluation of Efficacy of Different Immunization Strategies for Hepatitis C Virus

P. Klenerman, P. Simmonds, Isabelle Dietrich, 2019, Hepatology.

The generation of a simian adenoviral vectored HCV vaccine encoding genetically conserved gene segments to target multiple HCV genotypes

Caitlin E. Mullarkey, O. Pybus, P. Klenerman, 2018, Vaccine.

Combination vaccines: synergistic simultaneous induction of antibody and T-cell immunity

A. Moore, Claire L Hutchings, 2007, Expert review of vaccines.

Novel Protein and Poxvirus-Based Vaccine Combinations for Simultaneous Induction of Humoral and Cell-Mediated Immunity1

A. Hill, A. Moore, Claire L Hutchings, 2005, The Journal of Immunology.

Humoral and Cell-Mediated Immunity Combinations for Simultaneous Induction of Novel Protein and Poxvirus-Based Vaccine

A. Hill, A. Moore, Claire L Hutchings, 2005 .

A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine

R. Sinden, T. Lang, A. Hill, 2011, Vaccine.

Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults

A. Nicosia, P. Klenerman, A. Pollard, 2019, Journal of Infection.

Single-cell transcriptome analysis of CD8 + T-cell memory inflation

P. Klenerman, C. Willberg, C. D. de Lara, 2019, Wellcome open research.

The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV

P. Klenerman, E. Barnes, M. Ansari, 2020, Vaccines.

Correction: Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial

R. Sinden, A. Hill, G. Pluschke, 2011, PLoS ONE.

Clinical Assessment of a Recombinant Simian Adenovirus ChAd63: A Potent New Vaccine Vector

A. Folgori, R. Cortese, A. Nicosia, 2012, The Journal of infectious diseases.

New insights into the altered adhesive and mechanical properties of red blood cells parasitized by Babesia bovis

C. Lim, Claire L Hutchings, B. Cooke, 2007, Molecular microbiology.

A pan‐genotype hepatitis C virus viral vector vaccine generates T cells and neutralizing antibodies in mice

P. Klenerman, R. Center, E. Barnes, 2022, Hepatology.

Memory inflation following adenoviral vaccination depends on IL-21

P. Klenerman, N. Provine, Claire L Hutchings, 2018, Vaccine.

Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern

P. Klenerman, J. Knight, P. Phalora, 2021, Nature Communications.

Helicobacter hepaticus infection in BALB/c mice abolishes subunit-vaccine-induced protection against M. tuberculosis

Fiona Powrie, Claire Hutchings, F. Powrie, 2015, Vaccine.

Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response

P. Klenerman, Alexander Kanapin, Geng-Hung Liu, 2023, Nature Communications.

Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria

Lyric C. Bartholomay, John T. Harty, J. Harty, 2008, Proceedings of the National Academy of Sciences.

Multiple functions of human T cells generated by experimental malaria challenge

P. Bejon, A. Hill, S. Todryk, 2009, European journal of immunology.

T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

P. Klenerman, M. Pirmohamed, A. Sette, 2020, Nature Communications.

Adenoviral vaccine induction of CD8+ T cell memory inflation: Impact of co-infection and infection order

P. Klenerman, C. D. de Lara, Claire L Hutchings, 2017, PLoS pathogens.

MAIT cell activation augments adenovirus vector vaccine immunogenicity

A. Folgori, P. Klenerman, E. Barnes, 2020, Science.

Activation of MAIT cells plays a critical role in viral vector vaccine immunogenicity

A. Folgori, P. Klenerman, E. Barnes, 2019, bioRxiv.

Combination of Protein and Viral Vaccines Induces Potent Cellular and Humoral Immune Responses and Enhanced Protection from Murine Malaria Challenge

A. Hill, A. Moore, Claire L Hutchings, 2007, Infection and Immunity.

Induction and Maintenance of CX3CR1-Intermediate Peripheral Memory CD8+ T Cells by Persistent Viruses and Vaccines

A. Folgori, P. Klenerman, Leo Swadling, 2018, Cell reports.

Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial

R. Sinden, A. Hill, G. Pluschke, 2008, PloS one.

The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity

P. Klenerman, Geng-Hung Liu, N. L. La Thangue, 2023, Communications Biology.

A Novel Murine Cytomegalovirus Vaccine Vector Protects against Mycobacterium tuberculosis

P. Klenerman, U. Koszinowski, Z. Ruzsics, 2014, The Journal of Immunology.

Divergent memory responses driven by adenoviral vectors are impacted by epitope competition

P. Klenerman, B. Ludewig, C. Perez-Shibayama, 2019, European journal of immunology.

Helicobacter hepaticus infection in BALB/c mice abolishes subunit-vaccine-induced protection against M. tuberculosis

F. Powrie, Claire L Hutchings, E. Tchilian, 2015, Vaccine.