Xin He

发表

In vitro–in vivo correlations for three different commercial immediate-release indapamide tablets

Zi-qiang Li, P. Yaro, Xin He, 2014, Drug development and industrial pharmacy.

In Vitro-In Vivo Predictive Dissolution-Permeation-Absorption Dynamics of Highly Permeable Drug Extended-Release Tablets via Drug Dissolution/Absorption Simulating System and pH Alteration

Zi-qiang Li, Xin He, Shuang Tian, 2018, AAPS PharmSciTech.

Physiologically Based In vitro Models to Predict the Oral Dissolution and Absorption of a Solid Drug Delivery System.

Zi-qiang Li, Xin He, 2015, Current drug metabolism.

Alkaloids from Mahonia bealei posses anti-H⁺/K⁺-ATPase and anti-gastrin effects on pyloric ligation-induced gastric ulcer in rats.

Chong-Zhi Wang, C. Yuan, Xin He, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity

M. Fink, Xin He, R. Yang, 2009, Critical care.

Chinese medicine GeGen-DanShen extract protects from myocardial ischemic injury through promoting angiogenesis via up-regulation of VEGF/VEGFR2 signaling pathway.

Chong-Zhi Wang, C. Yuan, Xin He, 2020, Journal of ethnopharmacology.

Absorption Properties of Luteolin and Apigenin in Genkwa Flos Using In Situ Single-Pass Intestinal Perfusion System in the Rat.

Xin He, Zijing Song, Cui-Ping Jiang, 2017, The American journal of Chinese medicine.

The enhancement mechanism of wine-processed Radix Scutellaria on NTG-induced migraine rats.

Chong-Zhi Wang, C. Yuan, Xin He, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Research progress in stroke-induced immunodepression syndrome (SIDS) and stroke-associated pneumonia (SAP)

Shi-feng Chu, N. Chen, Xin He, 2018, Neurochemistry International.

Fennel main constituent, trans-anethole treatment against LPS-induced acute lung injury by regulation of Th17/Treg function

Xin He, Lijun An, Si-chao Zhang, 2018, Molecular medicine reports.

Self-Nanoemulsifying Drug Delivery System of Genkwanin: A Novel Approach for Anti-Colitis-Associated Colorectal Cancer

Xin He, Weiguo Chen, Chun-feng Zhang, 2021, Drug design, development and therapy.

Differences in xanthotoxin metabolites in seven mammalian liver microsomes.

Xin He, Lei Zhang, Lili Wang, 2020, Experimental and therapeutic medicine.

Studies on the metabolites difference of psoralen/isopsoralen in human and six mammalian liver microsomes in vitro by UHPLC–MS/MS

Xin He, Yetao Ma, Lili Wang, 2017, Journal of pharmaceutical and biomedical analysis.

Polysaccharide of Radix Pseudostellariae Improves Chronic Fatigue Syndrome Induced by Poly I:C in Mice

Xin He, Yubin Luo, Yu-feng Xia, 2011, Evidence-based complementary and alternative medicine : eCAM.

Antioxidative Activity of Flavonoids from Abrus cantoniensis against Ethanol-Induced Gastric Ulcer in Mice

Chong-Zhi Wang, C. Yuan, Xin He, 2015, Planta Medica.

Simultaneous Evaluation of Dissolution and Permeation of Oral Drug Solid Formulations for Predicting Absorption Rate–Limiting Factors and In Vitro–In Vivo Correlations: Case Study Using a Poorly Soluble Weakly Basic Drug

Zi-qiang Li, Xin He, Mingjin Xun, 2019, AAPS PharmSciTech.

Distribution of cholesterol 24-hydroxylase in the monkey brain

W. Ong, Xin He, Huaxiang Qian, 2010, Neuroscience bulletin.

Anti-rheumatoid arthritic activity of flavonoids from Daphne genkwa.

Ping Li, Chong-Zhi Wang, C. Yuan, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Antioxidant effects of Genkwa flos flavonoids on Freund׳s adjuvant-induced rheumatoid arthritis in rats.

Ping Li, Chong-Zhi Wang, C. Yuan, 2014, Journal of ethnopharmacology.

Protopanaxadiol, an Active Ginseng Metabolite, Significantly Enhances the Effects of Fluorouracil on Colon Cancer

T. He, Lian‐Wen Qi, Chong-Zhi Wang, 2015, Nutrients.

Periplocymarin is a potential natural compound for drug development: highly permeable with absence of P‐glycoprotein efflux and cytochrome P450 inhibitions

Xin He, Xiaoyan Shi, Chao Li, 2014, Biopharmaceutics & drug disposition.

Palmatine from Mahonia bealei attenuates gut tumorigenesis in ApcMin/+ mice via inhibition of inflammatory cytokines

Chong-Zhi Wang, C. Yuan, Xin He, 2016, Molecular medicine reports.

Changes in Brain Cholesterol Metabolome After Excitotoxicity

A. A. Farooqui, W. Ong, A. Jenner, 2010, Molecular Neurobiology.

Anti-arthritic effect of berberine on adjuvant-induced rheumatoid arthritis in rats.

Chong-Zhi Wang, C. Yuan, Xin He, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Identify super quality markers from prototype-based pharmacokinetic markers of Tangzhiqing tablet (TZQ) based on in vitro dissolution/ permeation and in vivo absorption correlations.

Zi-qiang Li, Yan-fen Li, Baohe Wang, 2018, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Da-Bu-Yin-Wan and Qian-Zheng-San, two traditional Chinese herbal formulas, up-regulate the expression of mitochondrial subunit NADH dehydrogenase 1 synergistically in the mice model of Parkinson's disease.

Xin He, Yi Zhang, Hong-mei Sun, 2013, Journal of ethnopharmacology.

Comprehensive Evaluation on Anti-Inflammatory and Anti-Angiogenic Activities in Vitro of Fourteen Flavonoids from Daphne Genkwa based on the Combination of Efficacy Coefficient Method and Principal Component Analysis.

Chong-Zhi Wang, C. Yuan, Xin He, 2020, Journal of ethnopharmacology.

Cytoglobin Exhibits Anti-Fibrosis Activity on Liver In Vivo and In Vitro

Lifang Yin, Wutong Wu, Xin He, 2011, The protein journal.

Research development on volatile oil from chuanxiong rhizoma

Xin He, Jipeng Hou, 2012 .

CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses

C. Chen, Shi-feng Chu, N. Chen, 2018, Acta Pharmacologica Sinica.

Mechanism-based inhibition of CYPs and RMs-induced hepatoxicity by rutaecarpine

Xin He, Li-li Wang, Lijun An, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

CYP450s-Activity Relations of Celastrol to Interact with Triptolide Reveal the Reasons of Hepatotoxicity of Tripterygium wilfordii

Y. Kanai, Xin He, Lili Wang, 2019, Molecules.

Identification and characterization of reactive metabolites in myristicin-mediated mechanism-based inhibition of CYP1A2.

Xin He, Li-li Wang, Lijun An, 2015, Chemico-biological interactions.

IMM-H004, a coumarin derivative, attenuated brain ischemia/reperfusion injuries and subsequent inflammation in spontaneously hypertensive rats through inhibition of VCAM-1

N. Chen, Xin He, Peng-fei Yang, 2017 .

Potential Mechanism of Herb-Drug Interaction Mediated by Angelica dahurica: Inhibition on CYP3A Enzymes in Rats

Xin He, Xiaoyan Shi, J. Kabera, 2016 .

Wilforine, the Q-marker and PK-maker of Tripterygium glycosides tablet: Based on preparation quantitative analysis and PK-PD study.

Xin He, Zeng-guang Wu, Lijun An, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Antitumor Activity of Total Flavonoids from Daphne genkwa in Colorectal Cancer

Fei Li, Chong-Zhi Wang, C. Yuan, 2016, Phytotherapy research : PTR.

Hypocholesterolemic effect of emodin by simultaneous determination of in vitro and in vivo bile salts binding.

Fei Li, Chong-Zhi Wang, C. Yuan, 2016, Fitoterapia.

Gastroprotective effect of palmatine against acetic acid-induced gastric ulcers in rats

Chong-Zhi Wang, C. Yuan, Xin He, 2016, Journal of Natural Medicines.

Natural soluble epoxide hydrolase inhibitors from Inula helenium and their interactions with soluble epoxide hydrolase.

Jia-Rong Wu, Xiaochi Ma, Bao-jing Zhang, 2020, International journal of biological macromolecules.

Recent Advance in Studies on Angelica sinensis

Xin He, Xue-feng Xiao, Ling Fang, 2012 .

An important mechanism of herb-induced hepatotoxicity: To produce RMs based on active functional groups-containing ingredients from phytomedicine by binding CYP450s

Xin He, Lei Zhang, Li-li Wang, 2019, Chinese Herbal Medicines.

Identification and analysis of the reactive metabolites related to the hepatotoxicity of safrole

Xin He, Lei Zhang, Wen-li Liu, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Coordination Mechanism and Bio-Evidence: Reactive γ-Ketoenal Intermediated Hepatotoxicity of Psoralen and Isopsoralen Based on Computer Approach and Bioassay

Xin He, Yetao Ma, Lili Wang, 2017, Molecules.

Cytochrome P450 and P-Glycoprotein-Mediated Interactions Involving African Herbs Indicated for Common Noncommunicable Diseases

Xin He, Makafui Nyagblordzro, Lili Wang, 2017, Evidence-based complementary and alternative medicine : eCAM.

Herb-drug interactions involving drug metabolizing enzymes and transporters.

Xin He, Xiulin Yi, Changxiao Liu, 2011, Current drug metabolism.

Inhibition of Cytochrome P450 by Nomilin and Obacunone and Potential Mechanism in Human Liver Microsomes

Xin He, Junxiu Chen, Yaowen Fan, 2017 .

Novel Application of Natural Anisole Compounds as Enhancers for Transdermal Delivery of Ligustrazine.

Fei Li, Chong-Zhi Wang, C. Yuan, 2015, The American journal of Chinese medicine.

Liquid Crystalline Nanoparticles as an Ophthalmic Delivery System for Tetrandrine: Development, Characterization, and In Vitro and In Vivo Evaluation

Xin He, Changxiao Liu, Shiming Fang, 2016, Nanoscale Research Letters.

Intestinal absorptive transport of Genkwanin from Flos genkwa using a single-pass intestinal perfusion rat model.

Ping Li, Xin He, Su-Li Zhang, 2014, The American journal of Chinese medicine.

Simultaneous determination of andrographolide, dehydroandrographolide and neoandrographolide in dog plasma by LC-MS/MS and its application to a dog pharmacokinetic study of Andrographis paniculata tablet.

Zhenzhong Wang, W. Xiao, Xin He, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Human cytochrome P450 enzyme inhibition profile of three flavonoids isolated from Psoralea corylifolia: in silico predictions and experimental validation

Xin He, Lili Wang, Wen-li Liu, 2018 .

Chinese Herbal Medicine Hepatotoxicity: The Evaluation and Recognization Based on Large-scale Evidence Database

Rui Gao, Xin He, Lili Wang, 2018, Current drug metabolism.

A novel cationic nanostructured lipid carrier for improvement of ocular bioavailability: Design, optimization, in vitro and in vivo evaluation

Xin He, Changxiao Liu, Shiming Fang, 2016 .

Ginsenoside Rg1 attenuates okadaic acid induced spatial memory impairment by the GSK3β/tau signaling pathway and the Aβ formation prevention in rats.

Yan Liu, Zhao Zhang, Xin He, 2013, European journal of pharmacology.

Application of an in vitro DDASS to evaluate oral absorption of two chemicals simultaneously: establishment of a level A in vitro–in vivo correlation

Xin He, Xiaoyan Shi, Yanyan Xu, 2012, Drug development and industrial pharmacy.

Reactive metabolite activation by CYP2C19-mediated rhein hepatotoxicity

Xin He, Xin He, Li-Na He, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Inhibitory mechanisms of celastrol on human liver cytochrome P450 1A2, 2C19, 2D6, 2E1 and 3A4

Xin He, Lijun An, Lili Wang, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Up-regulation on cytochromes P450 in rat mediated by total alkaloid extract from Corydalis yanhusuo

Xin He, Yetao Ma, S. Feng, 2014, BMC Complementary and Alternative Medicine.

The In vitro/vivo Evaluation of Prepared Gastric Floating Tablets of Berberine Hydrochloride

Xin He, Chun‐Feng Zhang, Cheng-Long Cui, 2017, AAPS PharmSciTech.

Absorption characteristics of the total alkaloids from Mahonia bealei in an in situ single-pass intestinal perfusion assay.

Ping Li, Xin He, Yu-He Sun, 2014, Chinese journal of natural medicines.

Simultaneous determination of seven effective components of Tripterygium glycosides in human biological matrices by ultra performance liquid chromatography-triple quadrupole mass spectrometry.

Xin He, Yuhong Huang, Chunxiao Lv, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Rapid screening the potential mechanism-based inhibitors of CYP3A4 from Tripterygium wilfordi based on computer approaches combined with in vitro bioassay.

Xin He, Lijun An, Lili Wang, 2017, Bioorganic & medicinal chemistry.

Antitumor and immunomodulatory activity of genkwanin on colorectal cancer in the APC(Min/+) mice.

Fei Li, Chong-Zhi Wang, C. Yuan, 2015, International immunopharmacology.

A Metabolism-Based Synergy for Total Coumarin Extract of Radix Angelicae Dahuricae and Ligustrazine on Migraine Treatment in Rats

Xin He, Zhuo-han Hu, Cong Huang, 2018, Molecules.

Pharmacokinetic and Toxicological Characteristics of Tripterigium Glycosides and Their Derivatives.

Xin He, Makafui Nyagblordzro, Lijun An, 2018, Current drug metabolism.

Drug Design, Development and Therapy Dovepress

Xin He, Xiaoyan Shi, O. Martey, 2022 .

Apolipoprotein D modulates F2-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic injury

Xin He, Jinatta Jittiwat, A. A. Farooqui, 2009, Neuroscience Letters.

Th17/Treg Imbalance and Atherosclerosis

Xin He, Bo Liang, N. Gu, 2020, Disease markers.

Thermal effects on the dissolution enhancement of Radix scutellariae by wine-processing

Chong-Zhi Wang, C. Yuan, Xin He, 2016 .

Progress in pharmacological research of chemokine like factor 1 (CKLF1)

N. Chen, Xin He, Xiu-yun Song, 2018, Cytokine.

Role of Metabolic Enzymes P450 (CYP) on Activating Procarcinogen and their Polymorphisms on the Risk of Cancers.

Xin He, S. Feng, 2015, Current drug metabolism.

P-glycoprotein- and organic anion-transporting polypeptide-mediated transport of periplocin may lead to drug–herb/drug–drug interactions

Xin He, Xiaoyan Shi, O. Martey, 2014, Drug design, development and therapy.

Advance in Pre-Clinical Pharmacokinetics of Paeoniflorin, a Major Monoterpene Glucoside from the Root of Paeonia lactiflora

Xin He, Xiaoyan Shi, O. Martey, 2013 .

Mechanism-based inhibition of CYP450: an indicator of drug-induced hepatotoxicity.

Xin He, S. Feng, 2013, Current drug metabolism.

The mechanism and risk factors of clopidogrel-induced liver injury

Xin He, Shan Feng, Xin He, 2016, Drug and chemical toxicology.

Gastroprotective Effect of Alkaloids from Cortex Phellodendri on Gastric Ulcers in Rats through Neurohumoral Regulation

Fei Li, Chong-Zhi Wang, C. Yuan, 2016, Planta Medica.

Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium–coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12)

N. Anzai, S. Miyauchi, Xin He, 2019, The Journal of Physiological Sciences.

Study on dissolution and absorption of four dosage forms of isosorbide mononitrate: level A in vitro-in vivo correlation.

Yuefei Wang, Xiumei Gao, Zi-qiang Li, 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The use of an in vitro dissolution and absorption system to evaluate oral absorption of two weak bases in pH-independent controlled-release formulations.

Xin He, Y. Takekuma, M. Sugawara, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

American ginseng significantly reduced the progression of high-fat-diet-enhanced colon carcinogenesis in ApcMin/+mice

T. He, Chong-Zhi Wang, C. Yuan, 2015, Journal of ginseng research.

Herb medicine Gan-fu-kang attenuates liver injury in a rat fibrotic model.

Xin He, M. Jiang, Y. Jia, 2010, Journal of ethnopharmacology.

CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses

N. Chen, Zhong-Ping Feng, Hong-Shuo Sun, 2018, Acta Pharmacologica Sinica.

Screen of anti-migraine active compounds from Duijinsan by spectrum-effect relationship analysis and molecular docking.

Chong-Zhi Wang, C. Yuan, Xin He, 2021, Journal of ethnopharmacology.

Advances in Exosomes Derived from Different Cell Sources and Cardiovascular Diseases

Xin He, Bo Liang, Yu-Xiu Zhao, 2020, BioMed research international.

Development and application of a rapid and sensitive LC-MS/MS method for simultaneous quantification of six diterpene lactones in rats after oral administration of Rhizoma Dioscoreae Bulbiferae extract.

Xin He, Zeng-guang Wu, Cong Huang, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Wen-Dan Decoction Improves Negative Emotions in Sleep-Deprived Rats by Regulating Orexin-A and Leptin Expression

Cai Song, Xin He, Li-yan Wang, 2014, Evidence-based complementary and alternative medicine : eCAM.

Reactive metabolite activation by CYP2C19-mediated rhein hepatotoxicity

Xin He, Li-li Wang, Junxiu Chen, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Monocyclic monoterpenes as penetration enhancers of ligustrazine hydrochloride for dermal delivery

Fei Li, Chong-Zhi Wang, C. Yuan, 2016, Pharmaceutical development and technology.

The protective effect of ginko bilboa leaves injection on the brain dopamine in the rat model of cerebral ischemia/reperfusion injury.

Li-Ping Chen, Xin He, Gu Jin, 2014, African health sciences.

Development of a Bionic System for the Simultaneous Prediction of the Release/Absorption Characteristics of Enteric-Coated Formulations

Xiumei Gao, Zi-qiang Li, Xin He, 2013, Pharmaceutical Research.