Shiho Kurokawa

发表

Rice-based oral antibody fragment prophylaxis and therapy against rotavirus infection.

M. Oyama, H. Kiyono, H. Kozuka-Hata, 2013, The Journal of clinical investigation.

A rice-based soluble form of a murine TNF-specific llama variable domain of heavy-chain antibody suppresses collagen-induced arthritis in mice.

H. Kiyono, J. Scheller, M. Mejima, 2014, Journal of biotechnology.

Development of Antibody-Fragment–Producing Rice for Neutralization of Human Norovirus

H. Kiyono, Shintaro Sato, H. Ushijima, 2021, Frontiers in Plant Science.

A heterodimeric antibody fragment for passive immunotherapy against norovirus infection.

H. Kiyono, Shintaro Sato, Tomoyuki N. Tanaka, 2020, The Journal of infectious diseases.

Nanogel-Based PspA Intranasal Vaccine Prevents Invasive Disease and Nasal Colonization by Streptococcus pneumoniae

H. Kiyono, Shintaro Sato, Masafumi Yamamoto, 2013, Infection and Immunity.

Good manufacturing practices production of a purification-free oral cholera vaccine expressed in transgenic rice plants

H. Kiyono, M. Mejima, Shiho Kurokawa, 2015, Plant Cell Reports.

Oral rice-based vaccine induces passive and active immunity against enterotoxigenic E. coli-mediated diarrhea in pigs.

S. Ueda, H. Kiyono, D. Tokuhara, 2015, Vaccine.

Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines.

H. Kiyono, N. Harada, H. Tsukada, 2010, Nature materials.

RNAi-mediated suppression of endogenous storage proteins leads to a change in localization of overexpressed cholera toxin B-subunit and the allergen protein RAG2 in rice seeds

H. Kiyono, T. Masumura, Rika Nakamura, 2013, Plant Cell Reports.

Oral MucoRice expressing double-mutant cholera toxin A and B subunits induces toxin-specific neutralising immunity.

H. Kiyono, H. Yasuda, D. Tokuhara, 2009, Vaccine.

Erratum: Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

H. Kiyono, N. Harada, H. Tsukada, 2010 .

Human Norovirus Propagation in Human Induced Pluripotent Stem Cell–Derived Intestinal Epithelial Cells

H. Kiyono, Shintaro Sato, Shiho Kurokawa, 2018, Cellular and molecular gastroenterology and hepatology.

Determination of genomic location and structure of the transgenes in marker-free rice-based cholera vaccine by using whole genome resequencing approach

H. Kiyono, M. Mejima, Shiho Kurokawa, 2014, Plant Cell, Tissue and Organ Culture (PCTOC).

Secretory IgA-mediated protection against V. cholerae and heat-labile enterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine

H. Kiyono, T. Honda, D. Tokuhara, 2010, Proceedings of the National Academy of Sciences.

Seed Metabolome Analysis of a Transgenic Rice Line Expressing Cholera Toxin B-subunit

D. Ohta, H. Kiyono, A. Okazawa, 2017, Scientific Reports.

Comprehensive Gene Expression Profiling of Peyer’s Patch M Cells, Villous M-Like Cells, and Intestinal Epithelial Cells1

H. Kiyono, Masato Yoshida, O. Igarashi, 2008, The Journal of Immunology.

In Vivo Molecular Imaging Analysis of a Nasal Vaccine That Induces Protective Immunity against Botulism in Nonhuman Primates

H. Kiyono, N. Harada, H. Tsukada, 2010, The Journal of Immunology.

Immunity against Botulism in Nonhuman Nasal Vaccine That Induces Protective In Vivo Molecular Imaging Analysis of a and

H. Kiyono, N. Harada, H. Tsukada, 2010 .

Characterization and Specification of a Trivalent Protein-Based Pneumococcal Vaccine Formulation Using an Adjuvant-Free Nanogel Nasal Delivery System.

H. Kiyono, K. Akiyoshi, D. Briles, 2021, Molecular pharmaceutics.

Differential analyses of major allergen proteins in wild-type rice and rice producing a fragment of anti-rotavirus antibody.

M. Oyama, H. Kiyono, H. Kozuka-Hata, 2016, Regulatory toxicology and pharmacology : RTP.

MucoRice-cholera toxin B-subunit, a rice-based oral cholera vaccine, down-regulates the expression of α-amylase/trypsin inhibitor-like protein family as major rice allergens.

M. Oyama, H. Kiyono, T. Masumura, 2013, Journal of Proteome Research.

RNAi-mediated suppression of endogenous storage proteins leads to a change in localization of overexpressed cholera toxin B-subunit and the allergen protein RAG2 in rice seeds

H. Kiyono, T. Masumura, Rika Nakamura, 2013, Plant Cell Reports.

A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids

H. Kiyono, Shintaro Sato, T. Mizushima, 2017, Stem cell reports.

Specific Expression of Apolipoprotein A-IV in the Follicle-Associated Epithelium of the Small Intestine

H. Kiyono, D. Tokuhara, M. Mejima, 2014, Digestive Diseases and Sciences.

Induction of toxin-specific neutralizing immunity by molecularly uniform rice-based oral cholera toxin B subunit vaccine without plant-associated sugar modification.

M. Oyama, H. Kiyono, Kunisuke Tanaka, 2013, Plant biotechnology journal.

A Rice-Based Oral Cholera Vaccine Induces Macaque-Specific Systemic Neutralizing Antibodies but Does Not Influence Pre-Existing Intestinal Immunity1

C. Sasakawa, H. Kiyono, F. Ono, 2009, The Journal of Immunology.

Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress.

H. Kiyono, Masato Yoshida, S. Domino, 2011, Biochemical and biophysical research communications.

Oral MucoRice-CTB vaccine for safety and microbiota-dependent immunogenicity in humans: a phase 1 randomised trial.

S. Imoto, M. Nojima, H. Kiyono, 2021, The Lancet. Microbe.

Oral MucoRice-CTB vaccine is safe and immunogenic in healthy US adults.

H. Kiyono, Shiho Kurokawa, Y. Yuki, 2022, Vaccine.

Comparative whole-genome and proteomics analyses of the next seed bank and the original master seed bank of MucoRice-CTB 51A line, a rice-based oral cholera vaccine

M. Oyama, M. Nojima, H. Kiyono, 2021, BMC Genomics.

Determination of genomic location and structure of the transgenes in marker-free rice-based cholera vaccine by using whole genome resequencing approach

H. Kiyono, M. Mejima, Shiho Kurokawa, 2014, Plant Cell, Tissue and Organ Culture (PCTOC).

RNAi suppression of rice endogenous storage proteins enhances the production of rice-based Botulinum neutrotoxin type A vaccine.

H. Kiyono, D. Tokuhara, M. Mejima, 2012, Vaccine.

Comparative whole-genome analyses of selection marker–free rice-based cholera toxin B-subunit vaccine lines and wild-type lines

H. Kiyono, M. Mejima, Shiho Kurokawa, 2015, BMC Genomics.

Good manufacturing practices production of a purification-free oral cholera vaccine expressed in transgenic rice plants

H. Kiyono, M. Mejima, Shiho Kurokawa, 2016, Plant Cell Reports.

Cationic-nanogel nasal vaccine containing the ectodomain of RSV-small hydrophobic protein induces protective immunity in rodents

H. Kiyono, D. Tokuhara, Shiho Kurokawa, 2023, NPJ vaccines.

Replication of Human Sapovirus in Human-Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells

H. Kiyono, S. Okitsu, H. Ushijima, 2023, Viruses.

Lactobacilli as a Vector for Delivery of Nanobodies against Norovirus Infection

H. Kiyono, Shintaro Sato, L. Hammarström, 2022, Pharmaceutics.