I. Meijerman

发表

The Effect of St John’s Wort on the Pharmacokinetics of Docetaxel

J. Schellens, H. Rosing, J. Beijnen, 2013, Clinical Pharmacokinetics.

The role of nuclear receptors in pharmacokinetic drug-drug interactions in oncology.

J. Schellens, J. Beijnen, I. Meijerman, 2007, Cancer treatment reviews.

Detection of Single Nucleotide Polymorphisms in theABCG2Gene in a Dutch Population

J. Schellens, J. Beijnen, B. Koeleman, 2005, American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.

PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line

J. Schellens, J. Beijnen, I. Meijerman, 2009, Cancer Chemotherapy and Pharmacology.

The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers

J. Schellens, J. Beijnen, A. Goey, 2013, European Journal of Clinical Pharmacology.

Designing experiments for food-drug synergy: Health aspects

E. Schoen, J. Groten, V. Feron, 2006 .

In vitro characterization of the biotransformation of thiocoraline, a novel marine anti-cancer drug

J. Schellens, J. Beijnen, E. Brandon, 2004, Investigational New Drugs.

In vitro characterization of the human biotransformation and CYP reaction phenotype of ET-743 (Yondelis®, Trabectidin®), a novel marine anti-cancer drug

J. Schellens, J. Beijnen, E. Brandon, 2006, Investigational New Drugs.

In-vitro cytotoxicity of ET-743 (Trabectedin, Yondelis), a marine anti-cancer drug, in the Hep G2 cell line: influence of cytochrome P450 and phase II inhibition, and cytochrome P450 induction

J. Schellens, J. Beijnen, E. Brandon, 2005, Anti-cancer drugs.

Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 Induction

J. Schellens, J. Beijnen, I. Meijerman, 2008, Drug Metabolism and Disposition.

Effects of cytochrome P450 2C9 polymorphisms on phenprocoumon anticoagulation status

T. Schalekamp, I. Meijerman, E. Meegen, 2004, Clinical pharmacology and therapeutics.

Induction of apoptosis and changes in nuclear G-actin are mediated by different pathways: the effect of inhibitors of protein and RNA synthesis in isolated rat hepatocytes.

G. Mulder, I. Meijerman, J. Nagelkerke, 1999, Toxicology and applied pharmacology.

Effect of Chinese herbs on CYP3A4 activity and expression in vitro.

J. Schellens, J. Beijnen, I. Meijerman, 2013, Journal of ethnopharmacology.

Modulation of intercellular communication between smooth muscle cells by growth factors and cytokines.

W. Jongen, C. Lakemond, T. van der Wijk, 1996, European journal of pharmacology.

Screening for polymorphisms in the PXR gene in a Dutch population

J. Schellens, J. Beijnen, M. Deenen, 2006, European Journal of Clinical Pharmacology.

Development and validation of a LC-MS/MS method for the in vitro analysis of 1-hydroxymidazolam in human liver microsomes: application for determining CYP3A4 inhibition in complex matrix mixtures.

J. Schellens, H. Rosing, J. Beijnen, 2013, Biomedical chromatography : BMC.

Interleukin‐2–activated natural killer cells can induce both apoptosis and necrosis in rat hepatocytes

P. Kuppen, G. Mulder, I. Meijerman, 1999, Hepatology.

1577PGERMLINE TYMS GENOTYPE IS HIGHLY PREDICTIVE IN PATIENTS WITH ADVANCED COLORECTAL AND GASTROESOPHAGEAL CANCER INDEPENDENT OF FLUOROPYRIMIDINE PHARMACOLOGY: RESULTS FROM TWO PROSPECTIVE TRANSLATIONAL STUDIES.

J. Schellens, H. Rosing, J. Beijnen, 2014, Annals of oncology : official journal of the European Society for Medical Oncology.

Changes of G-actin localisation in the mitotic spindle region or nucleus during mitosis and after heat shock: a histochemical study of G-actin in various cell lines with fluorescent labelled vitamin D-binding protein.

G. Mulder, I. Meijerman, J. Nagelkerke, 1999, Biochimica et biophysica acta.

Prevention of cycloheximide-induced apoptosis in hepatocytes by adenosine and by caspase inhibitors.

G. Mulder, I. Meijerman, J. Nagelkerke, 1999, Biochemical pharmacology.

Remodeling of the actin cytoskeleton of target hepatocytes and NK cells during induction of apoptosis.

P. Kuppen, G. Mulder, I. Meijerman, 2001, Cell motility and the cytoskeleton.

Herb-drug interactions in oncology: focus on mechanisms of induction.

J. Schellens, J. Beijnen, I. Meijerman, 2006, The oncologist.

The bioanalysis of the major Echinacea purpurea constituents dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human plasma using LC-MS/MS.

J. Schellens, H. Rosing, J. Beijnen, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A sensitive LC-MS/MS method for the quantitative analysis of the Echinacea purpurea constituent undeca-2-ene-8,10-diynoic acid isobutylamide in human plasma.

J. Schellens, H. Rosing, J. Beijnen, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines.

J. Schellens, J. Beijnen, M. Deenen, 2006, Toxicology and applied pharmacology.

3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition.

J. Meulenbelt, M. van den Berg, M. V. van Duursen, 2011, Toxicology letters.

An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons.

Jos H Beijnen, Irma Meijerman, J. Schellens, 2003, Toxicology and applied pharmacology.

Genetic Polymorphisms of Drug-Metabolising Enzymes and Drug Transporters in the Chemotherapeutic Treatment of Cancer

J. Schellens, J. Beijnen, I. Meijerman, 2006, Clinical pharmacokinetics.

Pharmacogenetic Screening of the Gene Deletion and Duplications of CYP2D6

J. Schellens, J. Beijnen, L. Sanderson, 2007, Drug metabolism reviews.

Nuclear accumulation of G-actin in isolated rat hepatocytes by adenine nucleotides.

G. Mulder, I. Meijerman, J. Nagelkerke, 1997, Biochemical and biophysical research communications.

The effect of complementary and alternative medicines on CYP3A4‐mediated metabolism of three different substrates: 7‐benzyloxy‐4‐trifluoromethyl‐coumarin, midazolam and docetaxel

J. Schellens, H. Rosing, J. Beijnen, 2014, The Journal of pharmacy and pharmacology.

Pharmacogenetic Screening for Polymorphisms in Drug-Metabolizing Enzymes and Drug Transporters in a Dutch Population

J. Schellens, J. Beijnen, I. Meijerman, 2012, Molecular Diagnosis & Therapy.

Relevance of in vitro and clinical data for predicting CYP3A4-mediated herb-drug interactions in cancer patients.

J. Schellens, J. Beijnen, A. Goey, 2013, Cancer treatment reviews.

PXR-mediated P-glycoprotein induction by small molecule tyrosine kinase inhibitors.

J. Schellens, J. Beijnen, I. Meijerman, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Combined action and regulation of phase II enzymes and multidrug resistance proteins in multidrug resistance in cancer.

J. Schellens, J. Beijnen, I. Meijerman, 2008, Cancer treatment reviews.

Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor

J. H. Beijnen, J. Schellens, J. Beijnen, 2009, Cancer Chemotherapy and Pharmacology.

Milk Thistle’s Active Components Silybin and Isosilybin: Novel Inhibitors of PXR-Mediated CYP3A4 Induction

J. Schellens, J. Beijnen, I. Meijerman, 2013, Drug Metabolism and Disposition.

The effect of Echinacea purpurea on the pharmacokinetics of docetaxel.

J. Schellens, H. Rosing, J. Beijnen, 2013, British journal of clinical pharmacology.

In vitro characterization of the human biotransformation pathways of aplidine, a novel marine anti-cancer drug

J. Schellens, J. Beijnen, E. Brandon, 2007, Investigational New Drugs.

Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy

H. Rosing, J. Schellens, M. Joerger, 2015, Cancer Chemotherapy and Pharmacology.

The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers

J. Schellens, J. Beijnen, A. Goey, 2013, European Journal of Clinical Pharmacology.

The in‐vitro effect of complementary and alternative medicines on cytochrome P450 2C9 activity

J. Schellens, J. Beijnen, A. Goey, 2014, The Journal of pharmacy and pharmacology.

Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 Induction

I. Meijerman, S. Harmsen, J. H. Beijnen, 2008, Drug Metabolism and Disposition.

Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor Mediated Cyp3a4 Induction Dmd #17335 2 Ls180 as a Model to Study Cyp3a4 Induction

I. Meijerman, S. Harmsen, J. H. Beijnen, 2022 .

PXR-mediated P-glycoprotein induction by small molecule tyrosine kinase inhibitors.

I. Meijerman, S. Harmsen, R. Maas-Bakker, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Combined action and regulation of phase II enzymes and multidrug resistance proteins in multidrug resistance in cancer.

J. Schellens, J. Beijnen, I. Meijerman, 2008, Cancer treatment reviews.