J. Huber

发表

The Future of the Pharmaceutical Sciences and Graduate Education: Recommendations from the AACP Graduate Education Special Interest Group

J. Gobburu, S. Wu‐Pong, S. O’Barr, 2013, American Journal of Pharmaceutical Education.

Molecular physiology and pathophysiology of tight junctions in the blood–brain barrier

R. Egleton, J. Huber, T. Davis, 2001, Trends in Neurosciences.

The transcriptome of cerebral ischemia

Taura L. Barr, C. Rosen, J. Huber, 2012, Brain Research Bulletin.

Sigma (σ) receptor ligand, AC927 (N-phenethylpiperidine oxalate), attenuates methamphetamine-induced hyperthermia and serotonin damage in mice

A. Coop, Nidhi Kaushal, J. Huber, 2011, Pharmacology Biochemistry and Behavior.

Protection against hypoxia-induced increase in blood-brain barrier permeability: role of tight junction proteins and NFκB

R. Egleton, J. Huber, T. Davis, 2003, Journal of Cell Science.

Nitric oxide mediates hypoxia-induced changes in paracellular permeability of cerebral microvasculature.

J. Huber, T. Davis, Rachel C Brown, 2004, American journal of physiology. Heart and circulatory physiology.

Age and the Metabolic Syndrome as Risk Factors for Ischemic Stroke: Improving Preclinical Models of Ischemic Stroke

C. Rosen, B. Lucke-Wold, J. Huber, 2012, The Yale journal of biology and medicine.

Early disruptions of the blood–brain barrier may contribute to exacerbated neuronal damage and prolonged functional recovery following stroke in aged rats

Kimberly A. Houser, C. Rosen, J. Huber, 2008, Neurobiology of Aging.

Pluronic P85 Block Copolymer Enhances Opioid Peptide Analgesia

R. Egleton, J. Huber, T. Davis, 2002, Journal of Pharmacology and Experimental Therapeutics.

Aneurysmal Subarachnoid Hemorrhage and Neuroinflammation: A Comprehensive Review

G. E. Vates, J. Simard, C. Rosen, 2016, International journal of molecular sciences.

The role for infarct volume as a surrogate measure of functional outcome following ischemic stroke

C. Rosen, B. Lucke-Wold, J. Huber, 2016, Journal of systems and integrative neuroscience.

Neuroprotection for Ischemic Stroke: Moving Past Shortcomings and Identifying Promising Directions

C. Rosen, B. Lucke-Wold, J. Huber, 2013, International journal of molecular sciences.

A Clinically Relevant Thromboembolic Stroke Model in the Aged Rat

C. Rosen, J. Huber, R. Turner, 2012 .

Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery

C. Rosen, J. Bailes, A. L. Petraglia, 2015, Front. Neurol..

Potential age-dependent effects of estrogen on neural injury.

C. Rosen, J. Huber, R. Leon, 2011, The American journal of pathology.

Plasminogen activator inhibitor type 1 derived peptide, EEIIMD, diminishes cortical infarct but fails to improve neurological function in aged rats following middle cerebral artery occlusion

C. Rosen, K. Kelly, J. Huber, 2009, Brain Research.

Bryostatin Improves Survival and Reduces Ischemic Brain Injury in Aged Rats After Acute Ischemic Stroke

D. Alkon, C. Rosen, J. Huber, 2013, Stroke.

Elucidating the role of compression waves and impact duration for generating mild traumatic brain injury in rats

C. Rosen, J. Regele, B. Lucke-Wold, 2017, Brain injury.

Hypoxia‐inducible factor and nuclear factor kappa‐B activation in blood–brain barrier endothelium under hypoxic/reoxygenation stress

J. Huber, T. Davis, K. Witt, 2005, Journal of neurochemistry.

Streptozotocin-induced diabetes progressively increases blood-brain barrier permeability in specific brain regions in rats.

Kimberly A. Houser, J. Huber, R. Vangilder, 2006, American journal of physiology. Heart and circulatory physiology.

Sleep disruption and the sequelae associated with traumatic brain injury

C. Rosen, D. Miller, B. Lucke-Wold, 2015, Neuroscience & Biobehavioral Reviews.

Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations.

R. Egleton, J. Huber, T. Davis, 2005, American journal of physiology. Heart and circulatory physiology.

Improved blood-brain barrier penetration and enhanced analgesia of an opioid peptide by glycosylation.

R. Egleton, J. Huber, T. Davis, 2001, The Journal of pharmacology and experimental therapeutics.

Effect of reduced flow on blood–brain barrier transport systems

R. Egleton, J. Huber, T. Davis, 2001, Brain Research.

Assessment of Stereoselectivity of Trimethylphenylalanine Analogues of δ‐Opioid [D‐Pen2,D‐Pen5]‐Enkephalin

V. Hruby, H. Yamamura, R. Egleton, 2000 .

Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat

C. Rosen, J. O'Callaghan, D. Miller, 2010, Neuroscience.

Nicotine increases in vivo blood–brain barrier permeability and alters cerebral microvascular tight junction protein distribution

R. Egleton, T. Abbruscato, J. Huber, 2004, Brain Research.

Blood-brain barrier tight junctions are altered during a 72-h exposure to lambda-carrageenan-induced inflammatory pain.

R. Egleton, J. Huber, T. Davis, 2002, American journal of physiology. Heart and circulatory physiology.

Reduction of Endothelial Nitric Oxide Increases the Adhesiveness of Constitutive Endothelial Membrane ICAM-1 through Src-Mediated Phosphorylation

C. Rosen, F. Gao, B. Lucke-Wold, 2018, Front. Physiol..

Worsened outcome from middle cerebral artery occlusion in aged rats receiving 17β-estradiol.

C. Rosen, J. Huber, Xinlan Li, 2012, Endocrinology.

Diabetes, cognitive function, and the blood-brain barrier.

J. Huber, 2008, Current pharmaceutical design.

Bryostatin extends tPA time window to 6 h following middle cerebral artery occlusion in aged female rats.

D. Alkon, C. Rosen, J. Simpkins, 2015, European journal of pharmacology.

Sesamol: a Treatment for Diabetes-Associated Blood-Brain Barrier Dysfunction.

J. Huber, R. Vangilder, 2014, Postdoc journal : a journal of postdoctoral research and postdoctoral affairs.

Traumatic brain injury and epilepsy: Underlying mechanisms leading to seizure

C. Rosen, E. Tucker, B. Lucke-Wold, 2015, Seizure.

Risk Factors: Aging

C. Rosen, B. Lucke-Wold, J. Huber, 2017 .

Low-intensity Blast Wave Model for Preclinical Assessment of Closed-head Mild Traumatic Brain Injury in Rodents.

C. Rosen, F. Plattner, B. Lucke-Wold, 2020, Journal of visualized experiments : JoVE.

Age exaggerates proinflammatory cytokine signaling and truncates STAT3 signaling following ischemic stroke in the rat

J. O'Callaghan, S. Benkovic, J. Huber, 2011 .

Effect of lambda-carrageenan-induced inflammatory pain on brain uptake of codeine and antinociception.

J. Huber, T. Davis, V. Hau, 2004, Brain research.

Viability of microvascular endothelial cells to direct exposure of formalin, lambda-carrageenan, and complete Freund's adjuvant.

J. Huber, T. Davis, Rachel C Brown, 2002, European journal of pharmacology.

Administration of sesamol improved blood–brain barrier function in streptozotocin-induced diabetic rats

K. Kelly, J. Huber, M. Chua, 2009, Experimental Brain Research.

Single low-dose lipopolysaccharide preconditioning: neuroprotective against axonal injury and modulates glial cells

C. Rosen, B. Lucke-Wold, J. Huber, 2017, Neuroimmunology and neuroinflammation.

SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation

J. Huber, C. McCurdy, R. Matsumoto, 2013, Experimental Neurology.

A mouse Model of Focal Vascular Injury Induces Astrocyte Reactivity, Tau Oligomers, and Aberrant Behavior

C. Rosen, B. Lucke-Wold, J. Huber, 2017, Archives of neuroscience.

Endoplasmic Reticulum Stress Modulation as a Target for Ameliorating Effects of Blast Induced Traumatic Brain Injury.

C. Rosen, B. Lucke-Wold, J. Huber, 2017, Journal of neurotrauma.

Insulin enhancement of opioid peptide transport across the blood-brain barrier and assessment of analgesic effect.

R. Egleton, J. Huber, T. Davis, 2000, The Journal of pharmacology and experimental therapeutics.

Bryostatin-1 Restores Blood Brain Barrier Integrity following Blast-Induced Traumatic Brain Injury

D. Alkon, C. Rosen, B. Lucke-Wold, 2014, Molecular Neurobiology.

Effect of λ-carrageenan-induced inflammatory pain on brain uptake of codeine and antinociception

J. Huber, T. Davis, V. Hau, 2004, Brain Research.

Pain and the blood-brain barrier: obstacles to drug delivery.

A. Wolka, J. Huber, T. Davis, 2003, Advanced drug delivery reviews.

Conjugation of low molecular weight poly(ethylene glycol) to biphalin enhances antinociceptive profile.

M. Bentley, R. Egleton, M. J. Roberts, 2003, Journal of pharmaceutical sciences.

Common mechanisms of Alzheimer's disease and ischemic stroke: the role of protein kinase C in the progression of age-related neurodegeneration.

D. Alkon, C. Rosen, J. Simpkins, 2014, Journal of Alzheimer's disease : JAD.

Role of Microvascular Disruption in Brain Damage from Traumatic Brain Injury.

C. Rosen, J. Simpkins, B. Lucke-Wold, 2015, Comprehensive Physiology.

Combination treatment of r-tPA and an optimized human apyrase reduces mortality rate and hemorrhagic transformation 6h after ischemic stroke in aged female rats.

C. Rosen, B. Lucke-Wold, J. Huber, 2014, European journal of pharmacology.

A review of sleep deprivation studies evaluating the brain transcriptome

C. Rosen, J. O'Callaghan, D. Miller, 2014, SpringerPlus.

Effect of guanidino modification and proline substitution on the in vitro stability and blood-brain barrier permeability of endomorphin II.

A. Lipkowski, A. Misicka, J. Huber, 2002, Journal of pharmaceutical sciences.

SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation

J. O'Callaghan, J. Huber, C. McCurdy, 2014, Experimental Neurology.

Linking traumatic brain injury to chronic traumatic encephalopathy: identification of potential mechanisms leading to neurofibrillary tangle development.

C. Rosen, J. Bailes, B. Lucke-Wold, 2014, Journal of neurotrauma.

Metabolic Syndrome and its Profound Effect on Prevalence of Ischemic Stroke.

C. Rosen, B. Lucke-Wold, J. Huber, 2014, American medical student research journal.

Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy.

C. Rosen, J. Bailes, B. Omalu, 2016, Journal of neurosurgery.

Peptide drug modifications to enhance bioavailability and blood-brain barrier permeability

R. Egleton, J. Huber, T. Davis, 2001, Peptides.

Pharmacodynamic and Pharmacokinetic Characterization of Poly(ethylene Glycol) Conjugation to Met-enkephalin Analog [d-pen ]-enkephalin (dpdpe)

M. Bentley, H. Yamamura, H. Wei, 2022 .

Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability.

V. Hruby, H. Yamamura, F. Porreca, 2000, Journal of medicinal chemistry.

Improved bioavailability to the brain of glycosylated Met-enkephalin analogs

V. Hruby, H. Yamamura, R. Egleton, 2000, Brain Research.

Aging, the metabolic syndrome, and ischemic stroke: redefining the approach for studying the blood-brain barrier in a complex neurological disease.

C. Rosen, B. Lucke-Wold, J. Huber, 2014, Advances in pharmacology.

Pathophysiology of the vascular wall and its relevance for cerebrovascular disorders in aged rodents.

C. Rosen, L. Mogoantă, D. Pirici, 2010, Current neurovascular research.

Alterations in blood-brain barrier ICAM-1 expression and brain microglial activation after lambda-carrageenan-induced inflammatory pain.

J. Huber, T. Davis, C. Campos, 2006, American journal of physiology. Heart and circulatory physiology.

Bryostatin-1 Restores Blood Brain Barrier Integrity following Blast-Induced Traumatic Brain Injury

D. Alkon, C. Rosen, B. Lucke-Wold, 2015, Molecular Neurobiology.

Salubrinal reduces oxidative stress, neuroinflammation and impulsive-like behavior in a rodent model of traumatic brain injury

C. Rosen, B. Lucke-Wold, J. Huber, 2016, Brain Research.

Altering endoplasmic reticulum stress in a model of blast-induced traumatic brain injury controls cellular fate and ameliorates neuropsychiatric symptoms

C. Rosen, B. Lucke-Wold, J. Huber, 2014, Front. Cell. Neurosci..

Differential effects of diabetes on rat choroid plexus ion transporter expression.

R. Egleton, J. Huber, T. Davis, 2003, Diabetes.

Targeting the neurovascular unit for treatment of neurological disorders.

Taura L. Barr, C. Rosen, J. Huber, 2011, Pharmacology & therapeutics.

Inflammatory pain alters blood-brain barrier permeability and tight junctional protein expression.

R. Egleton, J. Huber, T. Davis, 2001, American journal of physiology. Heart and circulatory physiology.

C-reactive protein and long-term ischemic stroke prognosis

Laurie A. Theeke, Taura L. Barr, C. Rosen, 2014, Journal of Clinical Neuroscience.

NOX2 inhibition with apocynin worsens stroke outcome in aged rats

C. Rosen, K. Kelly, J. Huber, 2009, Brain Research.

Amelioration of nicotinamide adenine dinucleotide phosphate-oxidase mediated stress reduces cell death after blast-induced traumatic brain injury.

C. Rosen, J. Bailes, B. Lucke-Wold, 2015, Translational research : the journal of laboratory and clinical medicine.

Disparity among Neural Injury Models and the Unfolded Protein Response

C. Rosen, B. Lucke-Wold, J. Huber, 2014 .

The Mitochondrial mitoNEET Ligand NL-1 Is Protective in a Murine Model of Transient Cerebral Ischemic Stroke

W. Geldenhuys, J. Simpkins, P. Sullivan, 2021, Pharmaceutical Research.

Development of a fluorescence screening assay for binding partners of the iron-sulfur mitochondrial protein mitoNEET.

W. Geldenhuys, L. Hazlehurst, T. Long, 2023, Bioorganic & medicinal chemistry letters.

Ischemic Stroke Injury Is Mediated by Aberrant Cdk5

P. Greengard, P. Calabresi, A. Tozzi, 2014, The Journal of Neuroscience.

Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice

B. Lucke-Wold, J. Huber, R. Matsumoto, 2016, Neuroreport.

Modeling clinically relevant blast parameters based on scaling principles produces functional & histological deficits in rats

C. Rosen, J. Huber, R. Matsumoto, 2013, Experimental Neurology.

The science of cerebral ischemia and the quest for neuroprotection: navigating past failure to future success.

C. Rosen, J. Huber, R. Turner, 2013, Journal of neurosurgery.

Spinal cord injury Injury to any part of the spinal cord that leads to inflammation and secondary effects on the CNS Spinal impact model

C. Rosen, J. Simpkins, B. Lucke-Wold, 2015 .

The Quest to Model Chronic Traumatic Encephalopathy: A Multiple Model and Injury Paradigm Experience

C. Rosen, A. L. Petraglia, B. Lucke-Wold, 2015, Front. Neurol..

Exposure to mild blast forces induces neuropathological effects, neurophysiological deficits and biochemical changes

J. Bibb, C. Rosen, F. Plattner, 2018, Molecular Brain.

Elucidating the severity of preclinical traumatic brain injury models: a role for functional assessment?

C. Rosen, J. Bailes, B. Lucke-Wold, 2014, Neurosurgery.

Effects of aging on behavioral assessment performance: implications for clinically relevant models of neurological disease.

S. Martin, C. Rosen, J. Huber, 2012, Journal of neurosurgery.

Disparity among neural injury models and the unfolded protein response.

C. Rosen, B. Lucke-Wold, J. Huber, 2014, Journal of neurological disorders & stroke.

Disparity among Neural Injury Models and the Unfolded Protein Response

J. Huber, C. Rosen, A. Logsdon, 2014 .

Sleep disruption and the sequelae associated with traumatic brain injury

C. Rosen, D. Miller, B. Lucke-Wold, 2015, Neuroscience & Biobehavioral Reviews.

Novel mitoNEET ligand NL-1 improves therapeutic outcomes in an aged rat model of cerebral ischemia/reperfusion injury

W. Geldenhuys, J. Huber, P. Saralkar, 2022, Experimental Neurology.

Modeling clinically relevant blast parameters based on scaling principles produces functional & histological deficits in rats

C. Rosen, J. Huber, R. Matsumoto, 2013, Experimental Neurology.