Wentao Zhang

发表

In Vitro ADME Profiling Using High-Throughput RapidFire Mass Spectrometry

Lory R Tan, Xiang Wu, Jing Wang, 2012, Journal of biomolecular screening.

The design, synthesis, and biological evaluation of PIM kinase inhibitors.

Wei Xu, J. Nuss, Wentao Zhang, 2012, Bioorganic & medicinal chemistry letters.

SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors.

J. Martini, J. Nuss, Wentao Zhang, 2012, Bioorganic & medicinal chemistry letters.

Discovery of XL413, a potent and selective CDC7 inhibitor.

Wei Xu, Charles R. Holst, J. Nuss, 2012, Bioorganic & medicinal chemistry letters.

Identification of small molecule ceramide kinase inhibitors using a homogeneous chemiluminescence high throughput assay.

A. Joly, K. McMillan, Wentao Zhang, 2007, Assay and drug development technologies.

Characterization of the Activity of the PI3K/mTOR Inhibitor XL765 (SAR245409) in Tumor Models with Diverse Genetic Alterations Affecting the PI3K Pathway

K. Yamaguchi, D. J. Matthews, F. Yakes, 2014, Molecular Cancer Therapeutics.

Discovery and characterization of an inhibitor of glucosylceramide synthase.

K. Ogilvie, J. Nuss, S. Richards, 2012, Journal of medicinal chemistry.

In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer.

F. Yakes, A. Joly, Lora Zhao, 2013, Thyroid : official journal of the American Thyroid Association.

Identification and Characterization of Small-Molecule Inhibitors of the R132H/R132H Mutant Isocitrate Dehydrogenase 1 Homodimer and R132H/Wild-Type Heterodimer

Xiang Wu, Jing Wang, Wentao Zhang, 2014, Journal of biomolecular screening.

The Selective PI3K Inhibitor XL147 (SAR245408) Inhibits Tumor Growth and Survival and Potentiates the Activity of Chemotherapeutic Agents in Preclinical Tumor Models

K. Yamaguchi, D. J. Matthews, F. Yakes, 2015, Molecular Cancer Therapeutics.

Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase γ inhibitors.

Charles R. Holst, J. Nuss, Xiang Wu, 2012, Journal of medicinal chemistry.

The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors.

Wei Xu, Wei Cheng, F. Yakes, 2012, Bioorganic & medicinal chemistry letters.

Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90.

S. Malek, J. Martini, J. Nuss, 2012, Bioorganic & medicinal chemistry letters.

Discovery of a novel class of potent and orally bioavailable sphingosine 1-phosphate receptor 1 antagonists.

Aaron Shipway, L. Mattheakis, J. Nuss, 2012, Journal of medicinal chemistry.