S. Efange

发表

Cholinergic activity of aged rhesus monkeys revealed by positron emission tomography

H. D. Gage, R. Ehrenkaufer, H. Gage, 2001, Synapse.

Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment

T. Hoye, S. Efange, F. Ntie‐Kang, 2017, Natural Products and Bioprospecting.

Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from Scleria striatinux with antiplasmodial activity.

T. Hoye, S. Efange, R. Brun, 2009, Journal of natural products.

Natural products: a continuing source of inspiration for the medicinal chemist

S. Efange, S Mbua Ngale Efange, 2002 .

Modified ibogaine fragments: synthesis and preliminary pharmacological characterization of 3-ethyl-5-phenyl-1,2,3,4,5, 6-hexahydroazepino[4,5-b]benzothiophenes.

S. Efange, D. Mash, A. Khare, 1998, Journal of medicinal chemistry.

Isolation and identification of an antiparasitic triterpenoid estersaponin from the stem bark of Pittosporum mannii (Pittosporaceae)

Godfred A. Ayimele, S. Efange, Q. Bickle, 2013 .

Synthesis and Pharmacological Characterization of 4-[125I]-N-(N-Benzylpiperidin-4-yl)-4-iodobenzamide: A High Affinity σ Receptor Ligand for Potential Imaging of Breast Cancer

M. E. Gulden, W. Bowen, T. Moody, 1995 .

Potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium: Selective toxicity of 1-methyl-4-(4′-acetamidophenyl)-pyridinium and 1-methyl-4-cyclohexylpyridinium for dopaminergic neurons in culture

F. Hefti, S. Efange, P. Michel, 1990, Experimental Neurology.

Selective Visualization of Rodent Locus Ceruleus by a Radiolabeled N‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine Analog

H. Kung, F. Hefti, S. Efange, 1989, Journal of neurochemistry.

Toxic effects of potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium on cultured rat dopaminergic neurons.

F. Hefti, J. Sanchez-Ramos, S. Efange, 1989, The Journal of pharmacology and experimental therapeutics.

Pargyline‐Sensitive selective accumulation of a radiolabeled MPTP analog in the primate cerebral cortex and basal ganglia

H. Kung, S. Efange, A. Dutta, 1990, Synapse.

Synthesis and biological characterization of stable and radioiodinated (+/-)-trans-2-hydroxy-3-P[4-(3-iodophenyl)piperidyl]-1,2,3,4-tetrahydronaphthalene (3'-IBVM).

R. Mach, S. Efange, Z. Tu, 2000, Nuclear medicine and biology.

N-(3-Iodophenyl)trozamicol (IPHT) and related inhibitors of vesicular acetylcholine transport: synthesis and preliminary biological characterization.

R. Mach, S. Efange, S. Parsons, 1999, Nuclear medicine and biology.

In vivo imaging of the vesicular acetylcholine transporter and the vesicular monoamine transporter

S. Efange, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Vesicular Acetylcholine Transporter Density and Alzheimer’s Disease

J. Staley, E. Garland, S. Efange, 1997, Neurobiology of Aging.

Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter.

R. Mach, S. Efange, Z. Tu, 2010, Journal of medicinal chemistry.

Synthesis, In Vitro and In Vivo Evaluation of 18F-labeled PET Ligands for Imaging the Vesicular Acetylcholine Transporter

R. Mach, L. Jones, S. Efange, 2009 .

Vesamicol analogues as sigma ligands. Molecular determinants of selectivity at the vesamicol receptor.

R. Mach, S. Childers, C. Foulon, 1995, Biochemical pharmacology.

Age-related diminution of dopamine antagonist-stimulated vesamicol receptor binding.

S. Efange, A. Khare, R. B. Langason, 1996, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

In-vitro antimicrobial activity of Ageratum conyzoides (Linn) on clinical isolates of Helicobacter pylori

H. Luma, S. Efange, R. Ndip, 2009 .

Interaction of flexible analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of N-methyl-4-phenylpyridinium with highly purified monoamine oxidase A and B.

S. Efange, T. Singer, M. Krueger, 1992, Biochemistry.

The vesamicol receptor ligand (+)-meta-[125I]iodobenzyltrozamicol [(+)-[125I]-MIBT] reveals blunting of the striatal cholinergic response to dopamine D2 receptor blockade in the 6-hydroxydopamine (6-OHDA)-lesioned rat: possible implications for Parkinson's disease.

W. Low, S. Efange, A. Khare, 1996, Life sciences.

Pharmacological characterization of the vesamicol analogue (+)-[(125)I]MIBT in primate brain.

J. Staley, S. Efange, S. Parsons, 1997, European journal of pharmacology.

Comparative tissue distribution of conformationally restricted radioiodinated vesamicol receptor ligands.

S. Efange, A. Khare, R. B. Langason, 1995, Nuclear medicine and biology.

Isolation and Characterization of Sclerienone C from Scleria Striatinux

T. Hoye, S. Efange, K. Nyongbela, 2016, Natural product communications.

Occurrence of Sesquiterpene Derivatives in Scleria Striatonux De Wild (Cyperaceae)

K. Hostettmann, S. Efange, R. Brun, 2009, Natural product communications.

Synthesis and Biological Activity of 5-halo-2-Pyrimidinone 3′-Azido-2′,3′-Dideoxyribosides

S. Efange, A. Dutta, 1991 .

Vesicular acetylcholine transport inhibitor suppresses REM sleep

R. Lydic, S. Efange, M. Capece, 1997, Neuroreport.

In vivo imaging of the spinal cord cholinergic system with PET.

H. D. Gage, R. Ehrenkaufer, R. Mach, 1999, Journal of computer assisted tomography.

In vitro anti-Helicobacter pylori activity of extracts of selected medicinal plants from North West Cameroon.

H. Luma, S. Efange, L. Ndip, 2007, Journal of ethnopharmacology.

Spirofused tetrahydroisoquinoline-oxindole hybrids as a novel class of fast acting antimalarial agents with multiple modes of action

L. Ayong, S. Efange, R. Keumoe, 2020, Scientific Reports.

Acyclic analogues of 2-(4-phenylpiperidino)cyclohexanol (vesamicol): conformationally mobile inhibitors of vesicular acetylcholine transport.

S. Efange, A. Dutta, S. Parsons, 1991, Journal of medicinal chemistry.

3′,4′-Dihydro-2′H-spiro[indoline-3,1′-isoquinolin]-2-ones as potential anti-cancer agents: synthesis and preliminary screening

S. Efange, Maloba M M Lobe, 2020, Royal Society Open Science.

In vitro screening of 1-aryl-6-hydroxy-1,2,3,4-tetrahydroisoquinolines: Structure related activity against pathogenic bacteria

S. Efange, Joelle Ngo Hanna, M. Ngemenya, 2015 .

1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics evaluation

S. Efange, F. Ntie‐Kang, R. Brun, 2014 .

Constituents of Peucedanum zenkeri seeds and their antimicrobial effects.

M. Iwu, S. Efange, I. Khan, 2003, Die Pharmazie.

In vitro Antimicrobial Activity of Cameroonian Medicinal Plants on Clinical Isolates of Helicobacter pylori: Ageratum conyzoides

H. Luma, J. Akoachere, S. Efange, 2009 .

Isolation and characterization of filaricidal compounds from the stem bark of Voacanga africana, a plant used in the traditional treatment of onchocerciasis in Cameroon

F. Cho-Ngwa, S. Efange, J. Mbah, 2015 .

2-(2-Piperidyl)- and 2-(2-pyrrolidyl)chromans as nicotine agonists: synthesis and preliminary pharmacological characterization.

R. Papke, M. Kung, S. Efange, 2001, Journal of medicinal chemistry.

Lipophilic amino alcohols with calcium channel blocking activity.

J. Werth, S. Efange, A. Dutta, 1992, Biochemical pharmacology.

Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter.

R. Mach, L. Jones, S. Efange, 2009, Journal of medicinal chemistry.

Synthesis and biological activities of 2-Pyrimidinone Nucleosides. III.1,2 5-Alkynyl-2-Pyrimidinone 2′-Deoxyribosides

S. Efange, T. Bardos, Yung‐chi Cheng, 1985 .

Synthesis and Applications of Isotopically Labelled Compounds

S. Efange, 1990 .

Anti-herpes simplex virus activity of 5-substituted 2-pyrimidinone nucleosides

Y. Cheng, M. Fisher, S. Efange, 1989, Antimicrobial Agents and Chemotherapy.

Fundamentals of Nuclear Pharmacy. 3rd ed

S. Efange, 1993 .

Synthesis and biological activities of 2-pyrimidinone nucleosides. 2. 5-Halo-2-pyrimidinone 2'-deoxyribonucleosides.

Y. Cheng, S. Efange, H. Shih, 1985, Journal of medicinal chemistry.

Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes.

D. Mash, D. Passarella, B. Danieli, 2003, Bioorganic & Medicinal Chemistry.

Nature-inspired indolyl-2-azabicyclo[2.2.2]oct-7-ene derivatives as promising agents for the attenuation of withdrawal symptoms: synthesis of 20-desethyl-20-hydroxymethyl-11-demethoxyibogaine

D. Passarella, B. Danieli, S. Efange, 2006, Natural product research.

Flexible N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogues: synthesis and monoamine oxidase catalyzed bioactivation.

S. Efange, R. Remmel, A. Dutta, 1990, Journal of medicinal chemistry.

Direct cardiac effects of a novel vesamicol receptor ligand, m-iodobenzyl-trozamicol, assessed in the canine isolated, blood-perfused heart preparations.

K. Lurie, S. Efange, K. Hashimoto, 1999, Journal of cardiovascular pharmacology.

Morphine-induced spinal cholinergic activation: in vivo imaging with positron emission tomography

R. Ehrenkaufer, H. Gage, R. Mach, 2001, Pain.

PII: S0304-3959(00)00426-7

R. Ehrenkaufer, H. Gage, R. Mach, 2001 .

Textbook of Radiopharmacy: Theory and Practice

S. Efange, 1992 .

N-hydroxyalkyl derivatives of 3 beta-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters.

R. Mach, M. Kung, S. Efange, 1997, Journal of medicinal chemistry.

Synthesis and tissue distribution of iodine-125-labeled (m-[125I]iodobenzyl)trozamicol ([125I]MIBT): potential radioligand for mapping central cholinergic innervation

S. Efange, A. Khare, R. Michelson, 1993 .

Synthesis and tissue distribution of (m-[125I]iodobenzyl)trozamicol ([125I]MIBT): potential radioligand for mapping central cholinergic innervation.

S. Efange, A. Khare, R. Michelson, 1993, Journal of medicinal chemistry.

Synthesis and biological evaluation of radioiodinated N-2-(4-piperidyl)ethyl benzamides.

F. Hefti, S. Efange, B. Knusel, 1993, Nuclear Medicine and Biology.

(+)-p-([18F]fluorobenzyl)spirotrozamicol [(+)-[18F]spiro-FBT]: synthesis and biological evaluation of a high-affinity ligand for the vesicular acetylcholine transporter (VAChT).

M. Nader, R. Ehrenkaufer, T. Morton, 1999, Nuclear medicine and biology.

Spirovesamicols: conformationally restricted analogs of 2-(4-phenylpiperidino)cyclohexanol (vesamicol, AH5183) as potential modulators of presynaptic cholinergic function.

C. Foulon, S. Efange, S. Parsons, 1994, Journal of medicinal chemistry.

Nonsymmetrical bipiperidyls as inhibitors of vesicular acetylcholine storage.

S. Efange, R. Bau, S. Parsons, 1993, Journal of medicinal chemistry.

Radioiodinated 2-hydroxy-3-(4-iodophenyl)-1-(4-phenylpiperidinyl)propane: potential radiotracer for mapping central cholinergic innervation in vitro.

H. Kung, S. Efange, A. Dutta, 1992, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Technetium-99m bis (aminoethanethiol) complexes with amine sidechains--potential brain perfusion imaging agents for SPECT.

H. Kung, S. Efange, M. Blau, 1987, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Synthesis and biodistribution of 99mTc-labeled piperidinyl bis(aminoethanethiol) complexes: potential brain perfusion imaging agents for single photon emission computed tomography.

H. Kung, S. Efange, M. Blau, 1988, Journal of medicinal chemistry.

p-[18F]fluorobenzyltrozamicol ([18F]FBT): molecular decomposition- reconstitution approach to vesamicol receptor radioligands for positron emission tomography.

R. Mach, S. Efange, P. Nowak, 1994, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Molecular determinants in the bioactivation of the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

S. M. N. Efange, R. J. Boudreau, S. Efange, 1991, J. Comput. Aided Mol. Des..

Measurement of functional cholinergic innervation in rat heart with a novel vesamicol receptor ligand.

K. Lurie, S. Efange, S. McKnite, 1996, Nuclear medicine and biology.

Toxicity of Structural Analogs of 1-methyl-4-Phenyl Pyridinium (MPP+) and Related Compounds on Dopaminergic Neurons in Culture

F. Hefti, J. Sanchez-Ramos, S. Efange, 1988 .

Characterization and Distribution of Transferrin Receptors in the Rat Brain

D. Mash, W. Weiner, S. Efange, 1990, Journal of neurochemistry.

Postmortem stability of the GABAA receptor complex: a study using rat brain cerebrocortical membranes

F. Hefti, J. Sanchez-Ramos, S. Efange, 1990 .

Imaging of cholinergic terminals using the radiotracer [18F](+)‐4‐fluorobenzyltrozamicol: In vitro binding studies and positron emission tomography studies in nonhuman primates

M. Nader, R. Ehrenkaufer, T. Morton, 1997, Synapse.

Reproducibility of repeated measures of cholinergic terminal density using.

H. D. Gage, R. Ehrenkaufer, R. Mach, 2000, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Chromaproline and Chromaperidine, nicotine agonists, and Donepezil, cholinesterase inhibitor, enhance performance of memory tasks in ovariectomized rats

V. Luine, S. Efange, Z. Tu, 2002, Pharmacology Biochemistry and Behavior.

Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter.

R. Mach, S. Efange, Z. Tu, 2010, Journal of Medicinal Chemistry.

Hydroxylated decahydroquinolines as ligands for the vesicular acetylcholine transporter: synthesis and biological evaluation.

R. Mach, S. Efange, S. Parsons, 1999, Journal of medicinal chemistry.

Molecular size and flexibility as determinants of selectivity in the oxidation of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs by monoamine oxidase A and B.

S. Efange, A. Tan, M. Krueger, 1993, Journal of medicinal chemistry.