D. Eaton

发表

Isoflurane induces dopamine transporter trafficking into the cell cytoplasm

J. Votaw, M. Byas-Smith, D. Denson, 2004, Synapse.

Aldosterone-induced increases in superoxide production counters nitric oxide inhibition of epithelial Na channel activity in A6 distal nephron cells.

D. Eaton, Ling Yu, H. Bao, 2007, American journal of physiology. Renal physiology.

Loss of Primary Cilia Increases Polycystin-2 and TRPV4 and Appearance of a Non-selective Cation Channel in Mouse Cortical Collecting Duct.

D. Eaton, M. Bunni, Takamitsu Saigusa, 2019, American journal of physiology. Renal physiology.

Acute regulation of epithelial sodium channel by anionic phospholipids.

D. Eaton, He-ping Ma, He-ping Ma, 2005, Journal of the American Society of Nephrology : JASN.

Phosphatidylinositol 4,5-Bisphosphate (PIP2) Stimulates Epithelial Sodium Channel Activity in A6 Cells*

D. Eaton, G. Yue, B. Malik, 2002, The Journal of Biological Chemistry.

Cathepsin B Is Secreted Apically from Xenopus 2F3 Cells and Cleaves the Epithelial Sodium Channel (ENaC) to Increase Its Activity*

A. Alli, D. Eaton, H. Bao, 2012, The Journal of Biological Chemistry.

Invited review: biophysical properties of sodium channels in lung alveolar epithelial cells.

S. Matalon, A. Lazrak, L. Jain, 2002, Journal of applied physiology.

Effects of luminal Na+ on single Na+ channels in A6 cells, a regulatory role for protein kinase C.

D. Eaton, B. N. Ling, 1989, The American journal of physiology.

Regulation of angiotensin II-induced JAK2 tyrosine phosphorylation: roles of SHP-1 and SHP-2.

M. Marrero, D. Eaton, H. Ju, 1998, American journal of physiology. Cell physiology.

A novel role of BK potassium channel activity in preventing the development of kidney fibrosis.

H. Cai, D. Eaton, H. Xin, 2021, Kidney international.

Inhibition of αENaC expression and ENaC activity following blockade of the circadian clock-regulatory kinases CK1δ/ε.

L. Jeffers, Michelle L. Gumz, Jacob Richards, 2012, AJP - Renal Physiology.

The N-terminal 81-aa fragment is critical for UT-A1 urea transporter bioactivity.

Guangping Chen, J. Sands, D. Eaton, 2010, Journal of epithelial biology & pharmacology.

Lovastatin attenuates effects of cyclosporine A on tight junctions and apoptosis in cultured cortical collecting duct principal cells.

A. Alli, D. Eaton, He-ping Ma, 2013, American journal of physiology. Renal physiology.

Unoprostone activation of BK (KCa1.1) channel splice variants.

J. Cuppoletti, D. Eaton, Ling Yu, 2015, Biochimica et biophysica acta.

Basolateral membrane potential of a tight epithelium: Ionic diffusion and electrogenic pumps

D. Eaton, S. Lewis, N. K. Wills, 1978, The Journal of Membrane Biology.

Single-channel recordings from two types of amiloride-sensitive epithelial Na+ channels.

D. Eaton, K. L. Hamilton, K. Hamilton, 1986, Membrane biochemistry.

Single-channel recordings from amiloride-sensitive epithelial sodium channel.

D. Eaton, K. L. Hamilton, K. Hamilton, 1985, The American journal of physiology.

The Electrical Properties of Cells

D. Eaton, 2020 .

Removal of sodium channel inactivation in squid axon by the oxidant chloramine-T

D. Eaton, G. Wang, M. Brodwick, 1985, The Journal of general physiology.

Biphasic regulation of ENaC by TGF- and EGF in renal epithelial cells

D. Eaton, Q. Yue, B. Malik, 2009 .

Biphasic regulation of ENaC by TGF-{alpha} and EGF in renal epithelial cells.

D. Eaton, Q. Yue, B. Malik, 2009, American journal of physiology. Renal physiology.

Regulation of Lung Epithelial Sodium Channels by Cytokines and Chemokines

R. Hoover, D. Eaton, B. Wynne, 2017, Front. Immunol..

Influenza virus inhibits ENaC and lung fluid clearance.

R. Compans, P. Kamat, L. Jain, 2004, American journal of physiology. Lung cellular and molecular physiology.

Aldosterone induces ras methylation in A6 epithelia.

D. Eaton, N. Al-Baldawi, J. Stockand, 2000, American journal of physiology. Cell physiology.

The contribution of epithelial sodium channels to alveolar function in health and disease.

Michael Koval, L. Jain, D. Eaton, 2009, Annual review of physiology.

Pendrin gene ablation alters ENaC subcellular distribution and open probability.

Masayoshi Nanami, J. Verlander, D. Eaton, 2015, American journal of physiology. Renal physiology.

Contractile Force Is Enhanced in Aortas from Pendrin Null Mice Due to Stimulation of Angiotensin II-Dependent Signaling

R. Bonsall, L. Walker, J. Verlander, 2014, PloS one.

Pendrin modulates ENaC function by changing luminal HCO3-.

A. Weinstein, D. Eaton, S. Wall, 2010, Journal of the American Society of Nephrology : JASN.

Respiration and sodium transport in rabbit urinary bladder.

D. Eaton, S. Silverthorn, 1982, Biochimica et biophysica acta.

Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct

D. Eaton, M. Bunni, Takamitsu Saigusa, 2019 .

WNK 4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism

D. Denson, Bo Zhou, Dexuan Wang, 2011 .

WNK4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism.

D. Denson, Bo Zhou, Dexuan Wang, 2011, American journal of physiology. Renal physiology.

Inhibition of TRPC6 reduces non-small cell lung cancer cell proliferation and invasion

A. Alli, P. Doetsch, D. Eaton, 2016, Oncotarget.

Inhibition of TRPC 6 reduces non-small cell lung cancer cell proliferation and invasion

A. Alli, P. Doetsch, D. Eaton, 2022 .

Regulation of epithelial sodium channel trafficking by ubiquitination.

L. Jain, D. Eaton, Ling Yu, 2010, Proceedings of the American Thoracic Society.

Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.

W. Mitch, S. Price, D. Eaton, 2006, American journal of physiology. Renal physiology.

Aldosterone Modulates the Association between NCC and ENaC

R. Hoover, D. Eaton, F. Theilig, 2017, Scientific Reports.

Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits.

W. Mitch, S. Price, D. Eaton, 2005, American journal of physiology. Renal physiology.

Inhibition of sodium currents by local anesthetics in chloramine-T- treated squid axons. The role of channel activation

G. Strichartz, D. Eaton, G. Wang, 1987, The Journal of general physiology.

Stimulatory Role of SPAK Signaling in the Regulation of Large Conductance Ca2+-Activated Potassium (BK) Channel Protein Expression in Kidney

E. Delpire, Xiaonan H. Wang, R. Hoover, 2020, Frontiers in Physiology.

WNK1 activates large-conductance Ca2+-activated K+ channels through modulation of ERK1/2 signaling.

Xiuyan Feng, Dingying Gu, D. Eaton, 2015, Journal of the American Society of Nephrology : JASN.

WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination.

A. Alli, Dexuan Wang, D. Eaton, 2013, American journal of physiology. Renal physiology.

Regulation of amiloride-sensitive Na(+) transport by basal nitric oxide.

S. Matalon, K. Hardiman, D. Eaton, 2004, American journal of respiratory cell and molecular biology.

Ceramide mediates inhibition of the renal epithelial sodium channel by tumor necrosis factor-alpha through protein kinase C.

D. Eaton, H. Bao, Zhi-ren Zhang, 2007, American journal of physiology. Renal physiology.

with increased left atrial pressure Catecholamines increase lung edema clearance in rats

H. Bitterman, J. Sznajder, H. O'brodovich, 2014 .

Renal sodium channels: regulation and single channel properties.

A. Becchetti, D. Eaton, H. Ma, 1995, Kidney international.

The TNF-derived TIP peptide activates the epithelial sodium channel and ameliorates experimental nephrotoxic serum nephritis.

M. Madaio, Jian-Kang Chen, R. Lucas, 2019, Kidney international.

ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells.

D. Warnock, D. Eaton, He-ping Ma, 2002, American journal of physiology. Renal physiology.

Tyrosine kinase regulates epithelial sodium transport in A6 cells.

D. Eaton, A. Ohara, P. Matsumoto, 1993, The American journal of physiology.

Protein abundance of urea transporters and aquaporin 2 change differently in nephrotic pair-fed vs. non-pair-fed rats.

Xiaonan H. Wang, J. Sands, D. Eaton, 2012, American journal of physiology. Renal physiology.

High glucose induces podocyte apoptosis by stimulating TRPC6 via elevation of reactive oxygen species.

Dan Li, D. Eaton, He-ping Ma, 2013, Biochimica et biophysica acta.

Dual role of hydrogen peroxide as an oxidant in pneumococcal pneumonia.

Yunchao Su, A. Verin, D. Fulton, 2020, Antioxidants & redox signaling.

Regulating ENaC's gate.

D. Eaton, T. Kleyman, 2019, American journal of physiology. Cell physiology.

GM-CSF receptor expression and signaling is decreased in lungs of ethanol-fed rats.

J. Roman, D. Eaton, D. Guidot, 2006, American journal of physiology. Lung cellular and molecular physiology.

Chronic Ethanol Ingestion in Rats Decreases Granulocyte-Macrophage Colony-Stimulating Factor Receptor Expression and Downstream Signaling in the Alveolar Macrophage1

Bjoern Peters, D. Tscharke, J. Sidney, 2005, Journal of Immunology.

Chronic ethanol ingestion increases expression of the angiotensin II type 2 (AT2) receptor and enhances tumor necrosis factor-alpha- and angiotensin II-induced cytotoxicity via AT2 signaling in rat alveolar epithelial cells.

J. Roman, D. Eaton, R. Bechara, 2003, Alcoholism, clinical and experimental research.

Nitric oxide inhibits lung sodium transport through a cGMP-mediated inhibition of epithelial cation channels.

L. Jain, D. Eaton, L. Brown, 1998, American journal of physiology. Lung cellular and molecular physiology.

Ion Channels: An Overview

L. Jain, D. Eaton, Chang Song, 2021 .

Calmodulin and CaMKII modulate ENaC activity by regulating the association of MARCKS and the cytoskeleton with the apical membrane.

A. Alli, D. Eaton, Ling Yu, 2015, American journal of physiology. Renal physiology.

Role of sodium in mediator release from human basophils.

M. Kutner, T. F. Smith, D. Eaton, 1992, The Journal of allergy and clinical immunology.

Erythropoietin receptor-operated Ca2+ channels: Activation by phospholipase C-γ1

M. Marrero, D. Eaton, R. Venema, 1998 .

The inhibitory effect of Gβγ and Gβ isoform specificity on ENaC activity.

D. Eaton, Ling Yu, H. Bao, 2013, American journal of physiology. Renal physiology.

Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction

Yunchao Su, A. Verin, Guangyu Wu, 2017, Front. Immunol..

Beta-adrenergic regulation of amiloride-sensitive lung sodium channels.

L. Jain, D. Eaton, Xi-Juan Chen, 2002, American journal of physiology. Lung cellular and molecular physiology.

Hypotonic stress upregulates β- and γ-ENaC expression through suppression of ERK by inducing MKP-1.

D. Eaton, Y. Marunaka, N. Niisato, 2012, American journal of physiology. Renal physiology.

A novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activation.

Richard E. White, J. Pittet, A. Verin, 2014, American journal of respiratory and critical care medicine.

Nitric oxide inhibits lung sodium transport through a cGMP-mediated inhibition of epithelial cation channels.

L. Jain, D. Eaton, L. Brown, 1998, The American journal of physiology.

Regulation of the epithelial sodium channel by phosphatidylinositides: experiments, implications, and speculations

D. Eaton, He-ping Ma, C. Chou, 2007, Pflügers Archiv - European Journal of Physiology.

ENaC activity and expression is decreased in the lungs of protein kinase C-α knockout mice.

D. Eaton, H. Bao, A. Eaton, 2014, American journal of physiology. Lung cellular and molecular physiology.

Oxidative signaling in renal epithelium: Critical role of cytosolic phospholipase A2 and p38(SAPK).

J. Douglas, D. Eaton, M. Simonson, 2006, Free radical biology & medicine.

Ca(2+)-permeable channel associated with platelet-derived growth factor receptor in mesangial cells.

D. Eaton, B. N. Ling, H. Matsunaga, 1994, The American journal of physiology.

Regulation of mesangial cell ion channels by insulin and angiotensin II. Possible role in diabetic glomerular hyperfiltration.

D. Eaton, B. N. Ling, E. Seal, 1993, The Journal of clinical investigation.

ENaC is regulated by natriuretic peptide receptor-dependent cGMP signaling.

A. Alli, D. Eaton, H. Bao, 2013, American journal of physiology. Renal physiology.

Chloride channels in the apical membrane of a distal nephron A6 cell line.

D. Eaton, Y. Marunaka, 1990, The American journal of physiology.

Chronic ethanol ingestion in rats decreases granulocyte-macrophage colony-stimulating factor receptor expression and downstream signaling in the alveolar macrophage.

Bjoern Peters, V. Pasquetto, D. Tscharke, 1997, Journal of Immunology.

Lovastatin-Induced Phosphatidylinositol-4-Phosphate 5-Kinase Diffusion from Microvilli Stimulates ROMK Channels.

D. Humphrey, Guangping Chen, Xincheng Yao, 2015, Journal of the American Society of Nephrology : JASN.

Acid pH and weak acids induce Na−Cl contransport in the rabbit urinary bladder

Karen E. Johnson, M. S. Ifshin, D. Eaton, 2005, The Journal of Membrane Biology.

Bradykinin stimulates the tyrosine phosphorylation and bradykinin B2 receptor association of phospholipase C gamma 1 in vascular endothelial cells.

M. Marrero, J. Sun, D. Eaton, 1998, Biochemical and biophysical research communications.

Cell surface expression and turnover of the α-subunit of the epithelial sodium channel

Baofeng Hu, D. Eaton, B. An, 2001 .

Cytomegalovirus: sodium entry and development of cytomegaly in human fibroblasts.

M. Fons, T. Albrecht, D. Eaton, 1988, Virology.

Effects of nystatin on membrane conductance and internal ion activities inAplysia neurons

D. Eaton, J. Russell, M. Brodwick, 1977, The Journal of Membrane Biology.

Angiotensin II-induced Association of Phospholipase Cγ1 with the G-protein-coupled AT1 Receptor*

M. Marrero, D. Eaton, H. Ju, 1998, The Journal of Biological Chemistry.

Regulation of angiotensin II-induced JAK2 tyrosine phosphorylation: roles of SHP-1 and SHP-2.

M. Marrero, D. Eaton, H. Ju, 1998, The American journal of physiology.

Ethanol stimulates epithelial sodium channels by elevating reactive oxygen species.

D. Denson, D. Eaton, H. Bao, 2012, American journal of physiology. Cell physiology.

Epithelial Sodium Channel Regulation by Cell Surface-associated Serum- and Glucocorticoid-regulated Kinase 1*

M. Rajagopal, Alan C Pao, C. Charlton, 2011, The Journal of Biological Chemistry.

Regulation of Na+ Reabsorption by the Aldosterone-induced Small G Protein K-Ras2A*

D. Eaton, N. Al-Baldawi, J. Stockand, 1999, The Journal of Biological Chemistry.

Physiology of fetal lung fluid clearance and the effect of labor.

L. Jain, D. Eaton, 2006, Seminars in perinatology.

The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate.

A. Alli, R. Hoover, O. Pochynyuk, 2016, The Biochemical journal.

Transactivation of the IGF-1R by aldosterone.

Jennifer L. Holzman, D. Eaton, B. Duke, 2007, American journal of physiology. Renal physiology.

Transactivation of the IGF-1 R by aldosterone

Jennifer L. Holzman, D. Eaton, B. Duke, 2007 .

Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia.

D. Eaton, C. Hart, Ling Yu, 2005, American journal of physiology. Cell physiology.

Membrane Transport: Ionic Environments, Signal Transduction, and Development of Therapeutic Targets

A. Tomoda, A. Dinudom, D. Eaton, 2015, BioMed research international.

Aldosterone alters the open probability of amiloride-blockable sodium channels in A6 epithelia.

D. Eaton, T. Kleyman, A. E. Kemendy, 1992, The American journal of physiology.

The effect of rapamycin on single ENaC channel activity and phosphorylation in A6 cells.

D. Eaton, H. Bao, J. Johnson, 2000, American journal of physiology. Cell physiology.

Functional ion channels in pulmonary alveolar type I cells support a role for type I cells in lung ion transport.

L. Jain, D. Eaton, H. Bao, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Phosphatidylinositol 3,4,5-Trisphosphate Mediates Aldosterone Stimulation of Epithelial Sodium Channel (ENaC) and Interacts with γ-ENaC*

A. Vandewalle, S. Saxena, D. Eaton, 2005, Journal of Biological Chemistry.

Mechanisms of Aldosterone's Action on Epithelial Na + Transport

D. Eaton, G. Yue, B. Malik, 2001, The Journal of Membrane Biology.

Aldosterone Regulates Pendrin and Epithelial Sodium Channel Activity through Intercalated Cell Mineralocorticoid Receptor-Dependent and -Independent Mechanisms over a Wide Range in Serum Potassium.

J. Verlander, D. Eaton, S. Wall, 2020, Journal of the American Society of Nephrology : JASN.

Estradiol activates epithelial sodium channels in rat alveolar cells through the G protein-coupled estrogen receptor.

G. Neigh, Megan M. Greenlee, D. Eaton, 2013, American journal of physiology. Lung cellular and molecular physiology.

Inhibition of apical Na+ channels in rabbit cortical collecting tubules by basolateral prostaglandin E2 is modulated by protein kinase C.

K. Kokko, D. Eaton, B. N. Ling, 1992, The Journal of clinical investigation.

Differential Effects of Protein Kinase C on the Levels of Epithelial Na+ Channel Subunit Proteins*

D. Eaton, H. Bao, J. Stockand, 2000, The Journal of Biological Chemistry.

A possible role for phospholipase A2 in the action of general anesthetics.

D. Denson, D. Eaton, R. Worrell, 1996, The American journal of physiology.

Protein-protein interaction between cPLA2 and splice variants of alpha-subunit of BK channels.

D. Denson, Juan Li, D. Eaton, 2010, American journal of physiology. Cell physiology.

Protein-protein interaction between cPLA 2 and splice variants of-subunit of BK channels

D. Denson, Juan Li, D. Eaton, 2010 .

Contrasting effects of cPLA2 on epithelial Na+ transport.

D. Denson, D. Eaton, H. Bao, 2001, American journal of physiology. Cell physiology.

Contrasting effects of cPLA 2 on epithelial Na 1 transport

D. Denson, D. Eaton, H. Bao, 2001 .

The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit*

R. Lemmens‐Gruber, A. Alli, T. Chakraborty, 2016, The Journal of Biological Chemistry.

Amiloride-inhibited Na+ uptake into toad bladder microsomes is Na+-H+ exchange.

D. Eaton, E. Labelle, 1983, Biochimica et biophysica acta.

Rituximab inhibits Kv1.3 channels in human B lymphoma cells via activation of FcγRIIB receptors.

M. Yanda, D. Eaton, H. Bao, 2012, Biochimica et biophysica acta.

Ion Channels: ENaC

L. Jain, D. Eaton, Chang Song, 2021 .

14-3-3 gamma, a novel regulator of the large-conductance Ca2+-activated K+ channels.

H. Fu, Xiaonan H. Wang, R. Hoover, 2020, American journal of physiology. Renal physiology.

The Polarized Effect of Intracellular Calcium on the Renal Epithelial Sodium Channel Occurs as a Result of Subcellular Calcium Signaling Domains Maintained by Mitochondria*

D. Eaton, Ling Yu, H. Bao, 2015, The Journal of Biological Chemistry.

Effects of cardiogenic edema fluid on ion and fluid transport in the adult lung.

H. O'brodovich, L. Jain, D. Eaton, 2007, American journal of physiology. Lung cellular and molecular physiology.

channels in lung alveolar epithelial cells Invited Review: Biophysical properties of sodium

John P. Johnson, W. LaFramboise, S. Shetty, 2015 .

Regulation of Na+ channels in lung alveolar type II epithelial cells.

S. Matalon, Jane-Jane Chen, L. Jain, 2004, Proceedings of the American Thoracic Society.

highlighted topics Lung Edema Clearance: 20 Years of Progress Invited Review: Biophysical properties of sodium channels in lung alveolar epithelial cells

S. Matalon, A. Lazrak, L. Jain, 2002 .

Alveolar epithelial ion and fluid transport: β-adrenergic regulation of amiloride-sensitive lung sodium channels

L. Jain, D. Eaton, Xi-Juan Chen, 2002 .

Antisense oligonucleotides against the α-subunit of ENaC decrease lung epithelial cation-channel activity.

L. Jain, D. Eaton, B. Malik, 1999, American journal of physiology. Lung cellular and molecular physiology.

Regulation of an amiloride‐sensitive Na+‐permeable channel by a β2‐adrenergic agonist, cytosolic Ca2+ and Cl− in fetal rat alveolar epithelium

H. O'brodovich, D. Eaton, Y. Marunaka, 1999, The Journal of physiology.

ALUNG June 20/6

L. Jain, D. Eaton, B. Malik, 1999 .

Effects of prostaglandin E2 on amiloride-blockable Na+ channels in a distal nephron cell line (A6).

K. Kokko, D. Eaton, B. N. Ling, 1994, The American journal of physiology.

Cloning of the Proto-oncogene c-src from Rat Testis

D. Eaton, J. Stockand, B. Duke, 2001, DNA sequence : the journal of DNA sequencing and mapping.

ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase Cα knockout mice.

J. Sands, D. Eaton, H. Bao, 2014, American journal of physiology. Renal physiology.

Cell surface expression and turnover of the alpha-subunit of the epithelial sodium channel.

D. Eaton, P. Smith, B. An, 2001, American journal of physiology. Renal physiology.

Listeriolysin O Causes ENaC Dysfunction in Human Airway Epithelial Cells

Richard E. White, A. Verin, T. Chakraborty, 2018, Toxins.

A synthetic prostone activates apical chloride channels in A6 epithelial cells.

D. Eaton, H. Bao, J. Self, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Ionic permeabilities of anAplysia giant neuron

A. Brown, D. Eaton, J. Russell, 2005, The Journal of Membrane Biology.

Membrane Currents Carried by Ca, Sr, and Ba in Barnacle Muscle Fiber During Voltage Clamp

S. Hagiwara, D. Eaton, J. Fukuda, 1974, The Journal of general physiology.

Role of growth factors in mesangial cell ion channel regulation.

D. Eaton, H. Ma, B. N. Ling, 1995, Kidney international.

Basolateral P2X₄channels stimulate ENaC activity in Xenopus cortical collecting duct A6 cells.

D. Eaton, Ling Yu, H. Bao, 2014, American journal of physiology. Renal physiology.

Basolateral P 2 X 4 channels stimulate ENaC activity in Xenopus cortical collecting duct A 6 cells

D. Eaton, Ling Yu, H. Bao, 2014 .

Vander's Renal Physiology

Douglas C. Eaton, John P. Pooler, D. Eaton, 2002 .

Nystatin as a probe for investigating the electrical properties of a tight epithelium

S A Lewis, J. Diamond, D. Eaton, 1977, The Journal of general physiology.

Effect of divalent heavy metals on epithelial Na+ channels in A6 cells.

D. Eaton, Ling Yu, My N Helms, 2007, American journal of physiology. Renal physiology.

Cyclosporin A inhibits apical secretory K+ channels in rabbit cortical collecting tubule principal cells.

D. Eaton, B. N. Ling, Douglas C. Eaton, 1993, Kidney international.

Sulfhydryl reagents affect Na+ uptake into toad bladder membrane vesicles

D. Eaton, E. Labelle, Edward F. LaBelle, 2005, The Journal of Membrane Biology.

Ion Channels in Epithelial Tissue: Single-Channel Properties

D. Eaton, Y. Marunaka, B. N. Ling, 1992 .

The amiloride-blockable sodium channel of epithelial tissue.

D. Eaton, K. Hamilton, 1988, Ion channels.

Regulation of renal epithelial sodium channels

K. Kokko, D. Eaton, B. N. Ling, 1992, Molecular and Cellular Biochemistry.

Methylation Increases the Open Probability of the Epithelial Sodium Channel in A6 Epithelia*

A. Becchetti, D. Eaton, J. Stockand, 2000, The Journal of Biological Chemistry.

Isoprenylcysteine-O-carboxyl Methyltransferase Regulates Aldosterone-sensitive Na+ Reabsorption*

John P. Johnson, D. Eaton, N. Al-Baldawi, 1999, The Journal of Biological Chemistry.

S-Adenosyl-l-homocysteine Hydrolase Regulates Aldosterone-induced Na+ Transport*

D. Eaton, J. Stockand, Nabil F. Al-Baldawi, 1999, The Journal of Biological Chemistry.

Carboxylmethylation of the β Subunit of xENaC Regulates Channel Activity*

John P. Johnson, D. Benos, O. Weisz, 1998, The Journal of Biological Chemistry.

The mechanism of Na+ transport by rabbit urinary bladder

J. Diamond, D. Eaton, S. Lewis, 1976, The Journal of Membrane Biology.

Active and passive properties of rabbit descending colon: A microelectrode and nystatin study

S. A. Lewis, D. Eaton, S. Lewis, 1979, The Journal of Membrane Biology.

Intracellular sodium ion activity and sodium transport in rabbit urinary bladder.

D. Eaton, 1981, The Journal of physiology.

Ca2+ responses in cytomegalovirus-infected fibroblasts of human origin.

T. Albrecht, D. Eaton, M. Nokta, 1987, Virology.

Involvement of cytosolic Cl− in osmoregulation of α-ENaC gene expression

D. Eaton, Y. Marunaka, N. Niisato, 2004 .

Involvement of cytosolic Cl- in osmoregulation of alpha-ENaC gene expression.

D. Eaton, Y. Marunaka, N. Niisato, 2004, American journal of physiology. Renal physiology.

Chapter 3 Ion Channel Fluctuations: “Noise” and Single-Channel Measurements

D. Eaton, Y. Marunaka, 1990 .

Effects of vasopressin and cAMP on single amiloride-blockable Na channels.

D. Eaton, Y. Marunaka, 1991, The American journal of physiology.

Prolactin stimulates sodium and chloride ion channels in A6 renal epithelial cells.

Megan M. Greenlee, D. Eaton, H. Bao, 2015, American journal of physiology. Renal physiology.

Tetrodotoxin sensitivity of muscle action potentials in pufferfishes and related fishes

A. Grinnell, D. Eaton, Y. Kidokoro, 1974, Journal of comparative physiology.

Effects of saxitoxin analogues and ligand competition on sodium currents of squid axons.

S. Hall, D. Eaton, M. Brodwick, 1986, The American journal of physiology.

Epithelial Sodium Channels (ENaCs)

D. Eaton, T. L. Tai, He-ping Ma, 2006 .

Intracellular acidosis blocks the basolateral Na-K pump in rabbit urinary bladder.

D. Eaton, K. Hamilton, K. Johnson, 1984, The American journal of physiology.

Effects of barium on the potassium conductance of squid axon

D. Eaton, M. Brodwick, 1980, The Journal of general physiology.

G protein activation inhibits amiloride-blockable highly selective sodium channels in A6 cells.

D. Eaton, A. Ohara, H. Matsunaga, 1993, The American journal of physiology.

Epithelial Sodium Channels (ENaC)

D. Eaton, Chang Song, He-ping Ma, 2020, Studies of Epithelial Transporters and Ion Channels.

Prostaglandin E2 increases 7-pS Cl- channel density in the apical membrane of A6 distal nephron cells.

K. Kokko, D. Eaton, B. N. Ling, 1997, The American journal of physiology.

Role of the JAK/STAT signaling pathway in diabetic nephropathy.

M. Marrero, D. Stern, D. Eaton, 2006, American journal of physiology. Renal physiology.

Analysis of Aprotinin, a Protease Inhibitor, Action on the Trafficking of Epithelial Na+ Channels (ENaC) in Renal Epithelial Cells Using a Mathematical Model

Akiyuki Taruno, G. Pezzotti, D. Eaton, 2017, Cellular Physiology and Biochemistry.

Redox Regulation of Epithelial Sodium Channels Examined in Alveolar Type 1 and 2 Cells Patch-clamped in Lung Slice Tissue*

L. Jain, D. Eaton, J. Self, 2008, Journal of Biological Chemistry.

Expression of highly selective sodium channels in alveolar type II cells is determined by culture conditions.

L. Jain, D. Eaton, L. Brown, 2001, American journal of physiology. Lung cellular and molecular physiology.

Antisense oligonucleotides against the alpha-subunit of ENaC decrease lung epithelial cation-channel activity.

L. Jain, D. Eaton, B. Malik, 1999, The American journal of physiology.

Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells.

D. Eaton, Ling Yu, My N. Helms, 2008, American journal of physiology. Renal physiology.

Dale J. Benos, Ph.D. (1950-2010).

S. Matalon, D. Eaton, Sadis Matalon, 2011, American journal of physiology. Lung cellular and molecular physiology.

Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC.

A. Alli, Megan M. Greenlee, D. Eaton, 2017, American journal of physiology. Lung cellular and molecular physiology.

Phosphatidylinositol phosphate-dependent regulation of Xenopus ENaC by MARCKS protein.

A. Alli, D. Eaton, Ling Yu, 2012, American journal of physiology. Renal physiology.

Identification of an Amiloride Binding Domain within the α-Subunit of the Epithelial Na+ Channel*

D. Benos, T. Kieber‐Emmons, D. Eaton, 1997, The Journal of Biological Chemistry.

PIP2 Interacts Electrostatically with MARCKS-like Protein-1 and ENaC in Renal Epithelial Cells

D. Eaton, M. Yoshigi, Heping Ma, 2022, Biology.

Regulation of the amiloride-blockable sodium channel from epithelial tissue

K. Kokko, D. Eaton, Y. Marunaka, 1990, Molecular and Cellular Biochemistry.

β-Adrenergic agonists differentially regulate highly selective and nonselective epithelial sodium channels to promote alveolar fluid clearance in vivo.

L. Jain, D. Eaton, Ling Yu, 2012, American journal of physiology. Lung cellular and molecular physiology.

Purinergic Regulation of Amiloride‐Sensitive Lung Sodium Channels

L. Jain, D. Eaton, H. Bao, 2007 .

Knockout of mitochondrial voltage-dependent anion channel type 3 increases reactive oxygen species (ROS) levels and alters renal sodium transport

D. Eaton, H. Bao, Q. Yue, 2017, The Journal of Biological Chemistry.

(cid:1) -Adrenergic agonists differentially regulate highly selective and nonselective epithelial sodium channels to promote alveolar ﬂuid clearance in vivo

L. Jain, D. Eaton, Ling Yu, 2012 .

signaling - 2 channel activity and lung fluid balance in vivo via O Nadph oxidase regulates alveolar epithelial sodium

N. Murthy, Michael Koval, L. Jain, 2012 .

Dopamine activates amiloride-sensitive sodium channels in alveolar type I cells in lung slice preparations.

L. Jain, D. Eaton, H. Bao, 2006, American journal of physiology. Lung cellular and molecular physiology.

Dopamine regulation of amiloride-sensitive sodium channels in lung cells.

L. Jain, D. Eaton, My N. Helms, 2006, American journal of physiology. Lung cellular and molecular physiology.

ENaC inhibition stimulates HCl secretion in the mouse cortical collecting duct. I. Stilbene-sensitive Cl- secretion.

Masayoshi Nanami, J. Verlander, A. Weinstein, 2015, American journal of physiology. Renal physiology.

Phosphatase inhibitors increase the open probability of ENaC in A6 cells.

A. Becchetti, D. Eaton, T. Kleyman, 2002, American journal of physiology. Renal physiology.

S -adenosyl- L -homocysteine hydrolase is necessary for aldosterone-induced activity of epithelial Na 1 channels

A. Becchetti, D. Eaton, H. Bao, 2001 .

Steroids and Exogenous γ-ENaC Subunit Modulate Cation Channels Formed by α-ENaC in Human B Lymphocytes*

D. Warnock, S. Saxena, D. Eaton, 2004, Journal of Biological Chemistry.

Characterization of an amiloride binding region in the α-subunit of ENaC

D. Eaton, T. Kleyman, N. Saxena, 2003 .

Characterization of an amiloride binding region in the alpha-subunit of ENaC.

D. Eaton, T. Kleyman, N. Saxena, 2003, American journal of physiology. Renal physiology.

Identification of an amiloride binding domain within the alpha-subunit of the epithelial Na+ channel.

D. Benos, T. Kieber‐Emmons, C. Lin, 1997, The Journal of biological chemistry.

S-adenosyl-L-homocysteine hydrolase is necessary for aldosterone-induced activity of epithelial Na(+) channels.

A. Becchetti, D. Eaton, H. Bao, 2001, American journal of physiology. Cell physiology.

Sodium channel inactivation in squid axon is removed by high internal pH or tyrosine-specific reagents.

D. Eaton, M. Brodwick, 1978, Science.

Arginine-specific reagents remove sodium channel inactivation

B. Rudy, D. Eaton, G. Oxford, 1978, Nature.

Cell calcium and the control of membrane transport.

Lazaro J. Mandel, Douglas C. Eaton, D. Eaton, 1987, Society of General Physiologists series.

presence of moderate left atrial hypertension in sheep Alveolar epithelial fluid clearance persists in the

J. Sznajder, H. O'brodovich, L. Welch, 2015 .

Current-voltage relationship of the basolateral membrane of a tight epithelium.

M. S. Ifshin, D. Eaton, S. Lewis, 1979, Biochimica et biophysica acta.

Dichotomous Role of Tumor Necrosis Factor in Pulmonary Barrier Function and Alveolar Fluid Clearance

M. Ushio-Fukai, T. Chakraborty, R. Lucas, 2022, Frontiers in Physiology.

Cholinergic regulation of epithelial sodium channels in rat alveolar type 2 epithelial cells.

L. Jain, D. Eaton, H. Bao, 2013, American journal of physiology. Lung cellular and molecular physiology.

Amiloride-sensitive sodium channels in rabbit cortical collecting tubule primary cultures.

D. Eaton, B. N. Ling, C. F. Hinton, 1991, The American journal of physiology.

Regulation of ion channel structure and function by reactive oxygen-nitrogen species.

J. Stamler, J. Eu, S. Matalon, 2003, American journal of physiology. Lung cellular and molecular physiology.

Potassium permeable channels in primary cultures of rabbit cortical collecting tubule.

D. Eaton, B. N. Ling, C. F. Hinton, 1991, Kidney international.

Prostaglandin E2 activates clusters of apical Cl- channels in principal cells via a cyclic adenosine monophosphate-dependent pathway.

K. Kokko, D. Eaton, B. N. Ling, 1994, The Journal of clinical investigation.

Regulation of single sodium channels in renal tissue: a role in sodium homeostasis.

D. Eaton, K. Hamilton, 1986, Federation proceedings.

Expression of the Cystic Fibrosis Phenotype in a Renal Amphibian Epithelial Cell Line*

D. Eaton, J. Zuckerman, R. Worrell, 1997, The Journal of Biological Chemistry.

Eicosanoids modulate apical Ca(2+)-dependent K+ channels in cultured rabbit principal cells.

D. Eaton, B. N. Ling, C. L. Webster, 1992, American Journal of Physiology.

Effects of insulin and phosphatase on a Ca2(+)-dependent Cl- channel in a distal nephron cell line (A6)

D. Eaton, Y. Marunaka, Yoshinori Marunaka, 1990, The Journal of general physiology.

Effects of fatty acids on BK channels in GH(3) cells.

D. Denson, D. Eaton, R. Worrell, 2000, American journal of physiology. Cell physiology.

Ca2+ sensitivity of BK channels in GH3 cells involves cytosolic phospholipase A2.

D. Denson, D. Eaton, P. Middleton, 1999, American journal of physiology. Cell physiology.

MAL protein stabilizes luminal membrane PLCβ3 and negatively regulates ENaC in mouse cortical collecting duct cells.

A. Alli, D. Eaton, Q. Yue, 2019, American journal of physiology. Renal physiology.

ION TRANSPORT | Overview

L. Jain, D. Eaton, 2006 .

Lipid vesicle-mediated alterations of membrane cholesterol levels: Effects on Na+ and K+ currents in squid axon

M. Poznansky, D. Eaton, M. Brodwick, 2005, The Journal of Membrane Biology.

Effect of protein cross-linking reagents on membrane currents of squid axon.

R. Horn, D. Eaton, M. Brodwick, 1980, The American journal of physiology.

Cytosolic Phospholipase A2 Is Required for Optimal ATP Activation of BK Channels in GH3 Cells*

D. Denson, D. Eaton, R. Worrell, 2001, The Journal of Biological Chemistry.

Myristoylated alanine-rich C kinase substrate-like protein-1 regulates epithelial sodium channel activity in renal distal convoluted tubule cells

Lihua Wang, D. Eaton, B. Wynne, 2020 .

ENaC activity is regulated by calpain-2 proteolysis of MARCKS proteins.

A. Alli, D. Eaton, Ling Yu, 2017, American journal of physiology. Cell physiology.

Frontiers in Renal and Epithelial Physiology – Grand Challenges

D. Eaton, 2012, Front. Physiol..

Angiotensin II-induced Tyrosine Phosphorylation of Signal Transducers and Activators of Transcription 1 Is Regulated by Janus-activated Kinase 2 and Fyn Kinases and Mitogen-activated Protein Kinase Phosphatase 1*

M. Marrero, D. Eaton, V. J. Venema, 1998, The Journal of Biological Chemistry.

Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose.

Xiaodan Wang, M. Marrero, D. Eaton, 2002, Kidney international.

ION TRANSPORT | ENaC (Epithelial Sodium Channel)

L. Jain, D. Eaton, 2006 .

Angiotensin II Evokes Calcium-Mediated Signaling Events in Isolated Dog Pancreatic Epithelial Cells

D. Eaton, A. Fink, S. Lee, 2002, Pancreas.

Cation selectivity of the resting membrane of squid axon

S. Hagiwara, A. E. Stuart, D. Eaton, 1972, The Journal of Membrane Biology.

Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells.

S. Shaw, M. Marrero, D. Stern, 2006, American journal of physiology. Renal physiology.

Cytochalasin E alters the cytoskeleton and decreases ENaC activity in Xenopus 2F3 cells.

A. Alli, D. Eaton, Ling Yu, 2014, American journal of physiology. Renal physiology.

Chronic ethanol exposure alters the lung proteome and leads to mitochondrial dysfunction in alveolar type 2 cells.

A. Alli, D. Eaton, L. Brown, 2014, American journal of physiology. Lung cellular and molecular physiology.

ENaC Degradation in A6 Cells by the Ubiquitin-Proteosome Proteolytic Pathway*

W. Mitch, D. Eaton, H. Bao, 2001, The Journal of Biological Chemistry.

Inhibition of the JAK/STAT Signaling Pathway Prevents the High Glucose-Induced Increase in TGF-β and Fibronectin Synthesis in Mesangial Cells

Xiaodan Wang, M. Marrero, D. Eaton, 2002 .

Current-direction/amplitude-dependent single channel gating kinetics of mouse pannexin 1 channel: a new concept for gating kinetics

M. Sokabe, T. Nomura, Akiyuki Taruno, 2017, Scientific Reports.

Estradiol stimulates an anti-translocation expression pattern of glucocorticoid co-regulators in a hippocampal cell model

G. Neigh, Megan M. Greenlee, D. Eaton, 2013, Physiology & Behavior.

Scanning ion conductance microscopy: a nanotechnology for biological studies in live cells

A. Alli, D. Eaton, H. Bao, 2012, Front. Physio..

Mini Review Article Scanning Ion Conductance Microscopy: a Nanotechnology for Biological Studies in Live Cells Direct Current (dc) Mode

A. Alli, D. Eaton, H. Bao, 2022 .

Cyclic GMP-activated channel activity in renal epithelial cells (A6).

D. Eaton, Y. Marunaka, A. Ohara, 1991, Biochimica et biophysica acta.

Alveolar fluid transport: a changing paradigm.

L. Jain, D. Eaton, 2006, American Journal of Physiology - Lung cellular and Molecular Physiology.

Lovastatin inhibits human B lymphoma cell proliferation by reducing intracellular ROS and TRPC6 expression.

B. Shen, D. Eaton, A. Eaton, 2014, Biochimica et biophysica acta.

Active and passive Na+ fluxes across the basolateral membrane of rabbit urinary bladder

D. Eaton, A. Frace, S. Silverthorn, 2005, The Journal of Membrane Biology.

Acute ethanol induces apoptosis by stimulating TRPC6 via elevation of superoxide in oxygenated podocytes.

A. Alli, Lihua Wang, D. Eaton, 2015, Biochimica et biophysica acta.

Co-localization of the α-subunit of BK-channels and c-PLA2 in GH3 cells

D. Denson, Juan Li, D. Eaton, 2006 .

Expression of amiloride-blockable sodium channels in Xenopus oocytes.

D. Eaton, C. F. Hinton, 1989, The American journal of physiology.

Cryptdin 3 forms anion selective channels in cytoplasmic membranes of human embryonic kidney cells.

M. Selsted, W. Lencer, J. Madara, 2002, American journal of physiology. Gastrointestinal and liver physiology.

Chapter 13 Membrane Selectivity and Ion Activities of Mammalian Tight Epithelia

D. Eaton, S. Lewis, N. K. Wills, 1980 .

A study on the tridimensional distribution of somatosensory evoked responses in human thalamus to aid the placement of stimulating electrodes for treatment of pain.

P J Kelly, P. Kelly, D. Eaton, 1980, Acta neurochirurgica. Supplementum.

Analytical challenges in nanomedicine

Boris Mizaikoff, Christine Kranz, B. Mizaikoff, 2011, Analytical and bioanalytical chemistry.

ATP-dependent proton transport in human renal medulla.

D. Eaton, T. Dubose, E. Labelle, 1986, The American journal of physiology.

channels in A6 distal nephron cells ATP masks stretch activation of epithelial sodium

D. Warnock, D. Eaton, Zhen-Hong Zhou, 2016 .

MARCKS-Like Protein-1(MLP-1) regulates ENaC Activity in Renal Distal Convoluted Tubule Cells.

Lihua Wang, D. Eaton, B. Wynne, 2020, American journal of physiology. Cell physiology.

Luminal sodium entrythrough amiloride-sensitive, highly-selective sodium channels (ENaC) in the apical membrane of distal nephron epithelial cells is the rate-limiting step for hormonally

A. Becchetti, D. Eaton, T. Kleyman, 2002 .

Erythropoietin receptor-operated Ca2+ channels: activation by phospholipase C-gamma 1.

M. Marrero, D. Eaton, R. Venema, 1998, Kidney international.

Postnatal changes in the G-proteins, cyclic nucleotides and adenylyl cyclase activity in rabbit heart cells.

R. W. Joyner, D. Eaton, T. Akita, 1994, Journal of molecular and cellular cardiology.

Tea blocks potassium current in squid axon

R. Horn, D. Eaton, M. Brodwick, 1980 .

RESEARCH ARTICLE Ion Channels and Transporters in Lung Function and Disease Alveolar nonselective channels are ASIC1a/ (cid:2) -ENaC channels and contribute to AFC

A. Alli, Megan M. Greenlee, D. Eaton, 2017 .

Activation of BK channels in GH3 cells by a c-PLA2-dependent G-protein signaling pathway.

D. Denson, X. Wang, J. Li, 2005, Journal of neurophysiology.

-Dependent G-Protein Signaling Pathway 2 -PLA c Activation of BK Channels in GH3 Cells by a

X. Wang, J. Li, D. Eaton, 2015 .

Characterization of an amiloride binding region in the (cid:1) -subunit of ENaC

D. Eaton, T. Kleyman, N. Saxena, 2003 .

Intracellular calcium and extra-retinal photoreception of Aplysia Giant neurons.

A. Brown, D. Eaton, M. Brodwick, 1977, Journal of neurobiology.

Lack of urea transporters, UT-A1 and UT-A3, increases nitric oxide accumulation to dampen medullary sodium reabsorption through ENaC.

J. Sands, D. Eaton, H. Bao, 2019, American journal of physiology. Renal physiology.

Co-localization of the alpha-subunit of BK-channels and c-PLA2 in GH3 cells.

D. Denson, Juan Li, D. Eaton, 2006, Biochemical and biophysical research communications.

The effect of racemic ketamine on the large conductance Ca+2-activated potassium (BK) channels in GH3 cells

D. Denson, D. Eaton, P. Duchatelle, 1994, Brain Research.

Inhibition of αENaC expression and ENaC activity following blockade of the circadian clock-regulatory kinases CK1δ/ε.

L. Jeffers, Jacob Richards, K. Cheng, 2012, American journal of physiology. Renal physiology.

Effects of barium on the potassium conductance of squid axon

D. Eaton, M. Brodwick, 1980, The Journal of general physiology.

The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate.

A. Alli, R. Hoover, O. Pochynyuk, 2016, The Biochemical journal.

Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells.

Xiaodan Wang, M. Marrero, D. Eaton, 2002, Diabetes.

ENaC activity and expression is decreased in the lungs of protein kinase C-α knockout mice.

D. Eaton, H. Bao, A. Eaton, 2014, American journal of physiology. Lung cellular and molecular physiology.

Membrane Currents Carried by Ca, Sr, and Ba in Barnacle Muscle Fiber During Voltage Clamp

S. Hagiwara, D. Eaton, J. Fukuda, 1974, The Journal of general physiology.

Calmodulin and CaMKII modulate ENaC activity by regulating the association of MARCKS and the cytoskeleton with the apical membrane.

A. Alli, D. Eaton, Ling Yu, 2015, American journal of physiology. Renal physiology.

Ionic permeabilities of an Aplysia giant neuron.

A. Brown, D. Eaton, J. Russell, 1975, The Journal of membrane biology.

Nystatin as a probe for investigating the electrical properties of a tight epithelium

J. Diamond, D. Eaton, C. Clausen, 1977, The Journal of general physiology.

Hypertension and Sodium Channel Turnover

D. Eaton, B. Malik, He-ping Ma, 2006 .

CALL PAPERS Aldosterone and Epithelial Na (cid:1) Channels Phosphatidylinositol phosphate-dependent regulation of Xenopus ENaC by MARCKS protein

A. Alli, D. Eaton, Ling Yu, 2012 .

Estradiol stimulates an anti-translocation expression pattern of glucocorticoid co-regulators in a hippocampal cell model

G. Neigh, Megan M. Greenlee, D. Eaton, 2013, Physiology & Behavior.

Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction

Yunchao Su, A. Verin, Guangyu Wu, 2017, Front. Immunol..