A. Rostagno

J. Holton, T. Révész, N. Wood, 2001, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Binding of polymeric IgG to fibronectin in extracellular matrices: an in vitro paradigm for immune-complex deposition.

L. Gold, A. Rostagno, G. Gallo, 2002, Molecular immunology.

BRI2 homodimerizes with the involvement of intermolecular disulfide bonds

J. Ghiso, Maria Tsachaki, A. Rostagno, 2010, Neurobiology of Aging.

BRI2 Interacts with Amyloid Precursor Protein (APP) and Regulates Amyloid β (Aβ) Production*

J. Ghiso, Maria Tsachaki, A. Rostagno, 2005, Journal of Biological Chemistry.

Chromosome 13 dementia syndromes as models of neurodegeneration

G. Plant, J. Holton, T. Révész, 2001, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Proteomic analysis of exfoliation deposits.

Stefani N. Thomas, R. Ritch, J. Liebmann, 2007, Investigative ophthalmology & visual science.

Ion channel formation by N-terminally truncated Aβ (4-42): Relevance for the pathogenesis of Alzheimer's disease.

R. Lal, J. Ghiso, B. Kagan, 2020, Nanomedicine : nanotechnology, biology, and medicine.

Clusterin and Alzheimer's disease.

Agueda Rostagno, Jorge Ghiso, J. Ghiso, 2005, Sub-cellular biochemistry.

Fibronectin binds to amyloid P component. Localization of the binding site to the 31,000 dalton C-terminal domain.

A. Rostagno, B. Frangione, A. García-Pardo, 1986, Biochemical and biophysical research communications.

Biochemical studies on the interaction of fibronectin with Ig.

L. Gold, A. Rostagno, B. Frangione, 1991, Journal of immunology.

Biochemical analysis of the interaction of fibronectin with IgG and localization of the respective binding sites.

L. Gold, A. Rostagno, B. Frangione, 1996, Molecular immunology.

Biochemical characterization of the fibronectin binding sites for IgG.

L. Gold, A. Rostagno, B. Frangione, 1989, Journal of immunology.

Affinity of fibronectin for polyclonal IgG.

A. Rostagno, M. Salvarrey, 1989, Clinical and experimental immunology.

Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis

J. Ghiso, A. Rostagno, S. Fossati, 2020, Aging cell.

CEREBRAL AMYLOID ANGIOPATHY AND ALZHEIMER'S DISEASE.

T. Révész, J. Ghiso, A. Rostagno, 2010, Hirosaki igaku = Hirosaki medical journal.

Cerebral amyloidosis: amyloid subunits, mutants and phenotypes

T. Révész, J. Holton, J. Ghiso, 2010, Cellular and Molecular Life Sciences.

Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease

T. Révész, N. Wood, A. Lees, 2008, Neuropathology and applied neurobiology.

Genetic alterations of the BRI2 gene: familial British and Danish dementias.

J. Holton, T. Révész, H. Braendgaard, 2006, Brain pathology.

Familial Danish Dementia: A Novel Form of Cerebral Amyloidosis Associated with Deposition of Both Amyloid‐Dan and Amyloid‐Beta

G. Plant, T. Révész, C. Strand, 2002, Journal of neuropathology and experimental neurology.

A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred.

T Bek, T Revesz, A Rostagno, 2000, Proceedings of the National Academy of Sciences of the United States of America.

A stop-codon mutation in the BRI gene associated with familial British dementia

Agueda Rostagno, Jorge Ghiso, Ruben Vidal, 1999, Nature.

Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies

G. Plant, T. Révész, J. Holton, 2009, Acta Neuropathologica.

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

K. Blennow, G. Šimić, I. Kostović, 2020, Molecular Psychiatry.

“Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain”

K. Blennow, G. Šimić, I. Kostović, 2020, bioRxiv.

Sporadic and Familial Cerebral Amyloid Angiopathies

Janice L Holton, Tamas Revesz, Agueda Rostagno, 2002, Brain pathology.

N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer’s disease

T. Bayer, J. Wiltfang, O. Wirths, 2020, Neuropathology and applied neurobiology.

Complement Activation in Chromosome 13 Dementias

G. Plant, T. Révész, J. Holton, 2002, The Journal of Biological Chemistry.

Tumoral non‐amyloidotic monoclonal immunoglobulin light chain deposits (‘aggregoma’): presenting feature of B‐cell dyscrasia in three cases with immunohistochemical and biochemical analyses

L. Ylagan, J. Ghiso, A. Rostagno, 2002, British journal of haematology.

Proteomic Analysis Shows Constitutive Secretion of MIF and p53-associated Activity of COX-2−/− Lung Fibroblasts

Roderick V. Jensen, Mandar Dave, Abul Bashar Mir Md Khademul Islam, 2017, Genom. Proteom. Bioinform..

Association of clusterin with the BRI2-derived amyloid molecules ABri and ADan

T. Révész, J. Holton, J. Ghiso, 2021, Neurobiology of Disease.

Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease.

T. Wisniewski, J. Ghiso, A. Rostagno, 1992, The Biochemical journal.

Chromosome 13 dementias

J. Holton, T. Révész, J. Ghiso, 2005, Cellular and Molecular Life Sciences CMLS.

A Strategy for Designing a Peptide Probe for Detection of β‐Amyloid Oligomers

J. Kim, J. Ghiso, A. Rostagno, 2010, Chembiochem : a European journal of chemical biology.

Oxidative stress and mitochondria-mediated cell death mechanisms triggered by the familial Danish dementia ADan amyloid

J. Ghiso, A. Rostagno, Krysti L Todd, 2016, Neurobiology of Disease.

Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia.

L. Martinian, T. Révész, J. Holton, 2001, The American journal of pathology.

Functional and structural properties of lipid-associated apolipoprotein J (clusterin).

B. Zlokovic, J. Ghiso, M. Calero, 1999, The Biochemical journal.

Preferential association of serum amyloid P component with fibrillar deposits in familial British and Danish dementias: Similarities with Alzheimer's disease

G. Plant, T. Révész, J. Holton, 2007, Journal of the Neurological Sciences.

Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9*

J. Montaner, J. Ghiso, S. Blais, 2015, The Journal of Biological Chemistry.

In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein

J. Ghiso, Farron L. McIntee, S. Blais, 2016, Front. Aging Neurosci..

Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition.

T. Beach, P. Mathews, J. Ghiso, 2018, Biochimica et biophysica acta. Molecular basis of disease.

Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage

J. Ghiso, A. Rostagno, Krystal Sotolongo, 2020, Alzheimer's Research & Therapy.

Systemic Amyloid Deposits in Familial British Dementia*

T Lashley, T Revesz, A Rostagno, 2001, The Journal of Biological Chemistry.

Dutch and Arctic mutant peptides of beta amyloid(1-40) differentially affect the FGF-2 pathway in brain endothelium.

S. Donnini, M. Ziche, J. Ghiso, 2009, Experimental cell research.

Title Pyroglutamate formation at the N-termini of ABri molecules in familial British dementia is not restricted to the central nervous system

T. Révész, J. Ghiso, A. Tamaoka, 2016 .

PYROGLUTAMATE FORMATION AT THE N-TERMINI OF ABRI MOLECULES IN FAMILIAL BRITISH DEMENTIA IS NOT RESTRICTED TO THE CENTRAL NERVOUS SYSTEM.

T. Révész, J. Holton, J. Ghiso, 2010, Hirosaki igaku = Hirosaki medical journal.

Familial Danish Dementia

G. Plant, T. Révész, J. Holton, 2005, Journal of Biological Chemistry.

Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits.

Yun Lu, S. Greenberg, J. Ghiso, 2010, The American journal of pathology.

Matrix Metalloproteinase 2 (MMP-2) Degrades Soluble Vasculotropic Amyloid-β E22Q and L34V Mutants, Delaying Their Toxicity for Human Brain Microvascular Endothelial Cells*

J. Montaner, M. Boada, P. Couraud, 2010, The Journal of Biological Chemistry.

Clusterin and complement activation in exfoliation glaucoma.

R. Ritch, J. Liebmann, J. Ghiso, 2014, Investigative ophthalmology & visual science.

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides.

A Rostagno, B Frangione, J Ghiso, 2000, The Biochemical journal.

Molecular chaperons, amyloid and preamyloid lesions in the BRI2 gene‐related dementias: a morphological study

T. Révész, M. Verbeek, J. Holton, 2006, Neuropathology and applied neurobiology.

Amyloidosis associated with cerebral amyloid angiopathy: cell signaling pathways elicited in cerebral endothelial cells.

J. Ghiso, A. Rostagno, S. Fossati, 2014, Journal of Alzheimer's disease : JAD.

Comparison of the fibrin-binding activities in the N- and C-termini of fibronectin.

J. Schwarzbauer, L. Gold, A. Rostagno, 1999, The Biochemical journal.

Systemic Catabolism of Alzheimer's Aβ40 and Aβ42*

S. Gandy, J. Ghiso, M. Calero, 2004, Journal of Biological Chemistry.

Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid‐β variants in cells composing the cerebral vessel walls

P. Couraud, J. Meyerson, J. Ghiso, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Differential contribution of isoaspartate post-translational modifications to the fibrillization and toxic properties of amyloid β and the Asn23 Iowa mutation.

J. Ghiso, A. Rostagno, S. Fossati, 2013, The Biochemical journal.

Pathogenesis of Alzheimer’s Disease

A. Rostagno, 2022, International journal of molecular sciences.

Correction: Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

K. Blennow, G. Šimić, I. Kostović, 2021, Molecular Psychiatry.

Search for amyloid-binding proteins by affinity chromatography.

J. Ghiso, M. Calero, A. Rostagno, 2012, Methods in molecular biology.

Tauroursodeoxycholic acid prevents E22Q Alzheimer’s Aβ toxicity in human cerebral endothelial cells

J. Meyerson, J. Ghiso, C. Rodrigues, 2009, Cellular and Molecular Life Sciences.

BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production.

J. Ghiso, Maria Tsachaki, A. Rostagno, 2005, The Journal of biological chemistry.

Oxidative Stress, Chronic Inflammation, and Amyloidoses

F. Rizzi, A. Rostagno, A. Orzechowski, 2019, Oxidative medicine and cellular longevity.

Microglia produce the amyloidogenic ABri peptide in familial British dementia

J. Schott, T. Révész, D. Salih, 2023, bioRxiv.

Inherited Amyloidoses and Neurodegeneration: Familial British Dementia and Familial Danish Dementia

G. Plant, T. Révész, J. Holton, 2011 .

Primary structure of human plasma fibronectin. Characterization of a 38 kDa domain containing the C-terminal heparin-binding site (Hep III site) and a region of molecular heterogeneity.

A. Rostagno, B. Frangione, A. García-Pardo, 1987, The Biochemical journal.

O2-03-07 Biochemical analysis of Aβ amyloid deposits in the Iowa variant of Alzheimer's disease

S. Greenberg, J. Ghiso, A. Rostagno, 2004, Neurobiology of Aging.

Iowa Variant of Familial Alzheimer’s Disease Accumulation of Posttranslationally Modified A (cid:1) D23N in Parenchymal and Cerebrovascular Amyloid Deposits

Yun Lu, S. Greenberg, J. Ghiso, 2010 .

Co-existence of amyloid ADan and amyloid-beta in familial Danish dementia

T. Révész, J. Holton, H. Houlden, 2002 .

Oxidative stress and mitochondria-mediated cell death mechanisms triggered by the familial Danish dementia ADan amyloid

J. Ghiso, A. Rostagno, Krysti L Todd, 2016, Neurobiology of Disease.

Mitochondrial dysfunction induced by a post-translationally modified amyloid linked to a familial mutation in an alternative model of neurodegeneration.

J. Ghiso, A. Rostagno, Krysti L Todd, 2014, Biochimica et biophysica acta.

A decamer duplication in the BRI gene originates a de-novo amyloid peptide that causes dementia in a Danish kindred

G. Plant, T. Révész, T. Bek, 2000, Neurobiology of Aging.

Amino‐terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains

J. Ghiso, H. Klafki, A. Rostagno, 2024, Neuropathology and applied neurobiology.

Amyloidosis associated with cerebral amyloid angiopathy: cell signaling pathways elicited in cerebral endothelial cells.

J. Ghiso, A. Rostagno, S. Fossati, 2014, Journal of Alzheimer's disease : JAD.

Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9*

J. Montaner, J. Ghiso, S. Blais, 2015, The Journal of Biological Chemistry.

Erratum: Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies (Acta Neuropathologica (2009) vol. 118 (115-130) 10.1007/s00401-009-0501-8)

G. Plant, J. Holton, T. Révész, 2009 .

Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia

H. Houlden, J. Ghiso, A. Rostagno, 2024, Acta neuropathologica.

Functionally distinct pericyte subsets differently regulate amyloid-β deposition in patients with Alzheimer's disease.

J. Ghiso, A. Rostagno, Christopher Lawrence De Jesus, 2024, Brain pathology.