Michael Williams

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Chapter 1 – Reproducibility in Biomedical Research

K. Mullane, M. Curtis, Michael Williams, 2018 .

Unknown unknowns in biomedical research: does an inability to deal with ambiguity contribute to issues of irreproducibility?

K. Mullane, Michael Williams, 2015, Biochemical pharmacology.

Addressing Reproducibility: Peer Review, Impact Factors, Checklists, Guidelines, and Reproducibility Initiatives

K. Mullane, M. Curtis, Michael Williams, 2018 .

Enhancing reproducibility: Failures from Reproducibility Initiatives underline core challenges

K. Mullane, Michael Williams, 2017, Biochemical pharmacology.

Receptor Targets in Drug Discovery and Development

D. Triggle, C. Mehlin, Michael Williams, 2003 .

Systems and integrative biology as alternative guises for pharmacology: prime time for an iPharm concept?

Michael Williams, Michael Williams, 2005, Biochemical pharmacology.

Editorial Central & Peripheral Nervous Systems: Amyloid β Peptide in Alzheimer's Disease Pathology: Towards a Rational Basis for Drug Discovery?

Michael Williams, P. Puttfarcken, K. Shiosaki, 1995 .

Biomedical Research in the 21st Century: Multiple Challenges in Resolving Reproducibility Issues

K. Mullane, M. Curtis, Michael Williams, 2018 .

Qualitative pharmacology in a quantitative world: diminishing value in the drug discovery process.

Michael Williams, 2011, Current opinion in pharmacology.

Alzheimer's disease beyond amyloid: can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?

K. Mullane, Michael Williams, 2020, Biochemical pharmacology.

Progress in Alzheimer's disease drug discovery: an update.

Michael Williams, 2009, Current opinion in investigational drugs.

Chapter 4 – Reporting Results

Michael Williams, Michael J. Curtis, Kevin Mullane, 2018 .

Geoffrey Burnstock - An accidental pharmacologist.

F. Di Virgilio, K. Jacobson, Michael Williams, 2020, Biochemical pharmacology.

Defining and characterizing drug/compound function.

T. Kenakin, Michael Williams, 2014, Biochemical pharmacology.

Chapter 8 Developments in P2 receptor targeted therapeutics

Michael Williams, 1999 .

Chapter 28. Drug Discovery at the Molecular Level: A Decade of Radioligand Binding in Retrospect

Michael Williams, D. U'prichard, 1984 .

Target validation.

Michael Williams, 2003, Current opinion in pharmacology.

Developing predictive CSF biomarkers-a challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine.

G. Marek, D. Flood, Michael Williams, 2011, Biochemical pharmacology.

Alzheimer's disease (AD) therapeutics - 2: Beyond amyloid - Re-defining AD and its causality to discover effective therapeutics.

K. Mullane, Michael Williams, 2018, Biochemical pharmacology.

Alzheimer's disease (AD) therapeutics – 1: Repeated clinical failures continue to question the amyloid hypothesis of AD and the current understanding of AD causality

K. Mullane, Michael Williams, 2018, Biochemical pharmacology.

Neuronal nicotinic receptors: a perspective on two decades of drug discovery research.

S. Arneric, Michael Williams, Michael Williams, 2007, Biochemical pharmacology.

Guidelines for manuscript submission in the peer-reviewed pharmacological literature.

S J Enna, J. Piette, S. Enna, 2015, Biochemical pharmacology.

The Merck Index: an Encyclopedia of Chemicals, Drugs, and Biologicals. 14th Edition. Merck Inc., Whitehouse Station/Rahway, New Jersey, October 2006. Cloth 0-911910-00X. $125. pp. 2564.

Michael Williams, Michael Williams, 2006 .

Psychosocial assessment of functional gastrointestinal disorders in clinical practice.

K. Olden, A. Budavari, Michael P. Jones, 2005, Journal of clinical gastroenterology.

The fall and rise of pharmacology--(re-)defining the discipline?

Raymond J Winquist, K. Mullane, Michael Williams, 2014, Biochemical pharmacology.

Translational paradigms in pharmacology and drug discovery.

Raymond J Winquist, K. Mullane, Michael Williams, 2014, Biochemical pharmacology.

Chapter 1. The Decade of the Brain

Michael Williams, 1992 .

Preclinical Models of Alzheimer's Disease: Relevance and Translational Validity

K. Mullane, Michael Williams, 2019, Current protocols in pharmacology.

Commentary: genome-based CNS drug discovery: D-amino acid oxidase (DAAO) as a novel target for antipsychotic medications: progress and challenges.

Michael Williams, 2009, Biochemical pharmacology.

Irreproducibility in Preclinical Biomedical Research: Perceptions, Uncertainties, and Knowledge Gaps.

Michael Williams, M. Jarvis, Michael Williams, 2016, Trends in pharmacological sciences.

Report on EU–USA Workshop: How Systems Biology Can Advance Cancer Research (27 October 2008)

Olaf Wolkenhauer, Blaz Zupan, Ravi Iyengar, 2009, Molecular oncology.

Improving Translational Paradigms in Drug Discovery and Development

Michael Williams, 2021, Current protocols.

Reagent Validation to Facilitate Experimental Reproducibility

Michael Williams, Michael Williams, 2018, Current protocols in pharmacology.

Productivity Shortfalls in Drug Discovery: Contributions from the Preclinical Sciences?

Michael Williams, Michael Williams, 2011, Journal of Pharmacology and Experimental Therapeutics.

Drug Discovery and Development

Michael Williams, Michael Williams, Jeffrey B. Malick, 1987, Humana Press.

Animal models of asthma: reprise or reboot?

K. Mullane, Michael Williams, Michael Williams, 2014, Biochemical pharmacology.

The Decade of the Brain Initiative and Health Care Reform: Irreconcilable Differences?

Michael Williams, 1994 .

Chapter 1: Same brain, new decade: Challenges in CNS drug discovery in the postgenomic, proteomic era

M. Decker, Michael Williams, J. Coyle, 2001 .

Challenges in the Biomedical Research Enterprise in the 21st century: Antecedents in the writings of David Triggle.

C. Triggle, Michael Williams, 2015, Biochemical pharmacology.

Alzheimer's therapeutics: continued clinical failures question the validity of the amyloid hypothesis-but what lies beyond?

K. Mullane, Michael Williams, Michael Williams, 2013, Biochemical pharmacology.

Replicated, replicable and relevant-target engagement and pharmacological experimentation in the 21st century.

Michael Williams, Kevin Mullane, Terry Kenakin, 2014, Biochemical pharmacology.

The de-Alzheimerization of age-related dementias: implications for drug targets and approaches to effective therapeutics.

K. Mullane, Michael Williams, 2019, Current opinion in pharmacology.

Mitochondrial Function and Dysfunction: An Update

Michael Williams, R. Davis, 2012, Journal of Pharmacology and Experimental Therapeutics.

Translational semantics and infrastructure: another search for the emperor's new clothes?

K. Mullane, Michael Williams, 2012, Drug discovery today.

The Practice of Medicinal Chemistry, 4th Edition. Camille Wermuth, David Aldous, Pierre Raboisson and Didier Rognan. Academic Press, London, 2015. ISBN Print 9780124172050 $150; eBook 9780124172135. $150. pp xxii + 880.

Michael Williams, Michael Williams, 2016 .

Challenges in the Search for Drugs to Treat Central Nervous System Disorders

M. Williams, Michael Williams, M Williams, 2009, Journal of Pharmacology and Experimental Therapeutics.

Organizing for drug discovery.

M. Williams, Michael Williams, G. Neil, 1988, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.

Defining the role of pharmacology in the emerging world of translational research.

S. Enna, M. Williams, Michael Williams, 2009, Advances in pharmacology.

Developing predictive CSF biomarkers-a challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine.

G. Marek, D. Flood, Michael Williams, 2011, Biochemical pharmacology.

Prospects for neurodegenerative and psychiatric disorder drug discovery

S. Enna, Michael Williams, 2011, Expert opinion on drug discovery.