S. Chan

发表

RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.

G. Fu, M. Lanotte, S. Waxman, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome.

K. Polonsky, R. Bergenstal, S. Shoelson, 1984, The New England journal of medicine.

Evolution of the prohormone convertases: identification of a homologue of PC6 in the protochordate amphioxus.

D. Steiner, A. Oliva, S. Chan, 2000, Biochimica et biophysica acta.

Construction and selection of recombinant plasmids containing full-length complementary DNAs corresponding to rat insulins I and II.

D. Steiner, S. Chan, B. E. Noyes, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone.

D. Steiner, M. Nishi, G. Bell, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Structure and evolution of the insulin gene.

D. Steiner, S. Chan, S. Kwok, 1985, Annual review of genetics.

High-potency hybrid compounds related to insulin and amphioxus insulin-like peptide.

S. Gammeltoft, D. Steiner, S. Chan, 1994, Biochemistry.

Insulin-like compounds related to the amphioxus insulin-like peptide.

S. Gammeltoft, D. Steiner, S. Chan, 1994, Biochemistry.

Molecular cloning and sequencing of the cDNA for human membrane-bound carboxypeptidase M. Comparison with carboxypeptidases A, B, H, and N.

D. Steiner, R. Skidgel, S. Chan, 1989, The Journal of biological chemistry.

Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues.

R. Espinosa, D. Steiner, S. Chan, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Expression of multiple insulin and insulin-like growth factor receptor genes in salmon gill cartilage.

D. Steiner, S. Chan, E. Urbinati, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Structure and expression of the insulin-like peptide receptor from amphioxus.

D. Steiner, S. Chan, M. Pashmforoush, 1996, Molecular endocrinology.

Evolution of insulin-like growth factor binding proteins.

D. Steiner, J. Wallace, Z. Upton, 1993, Growth regulation.

Ontogeny of the insulin-like growth factor system (IGF-I, IGF-II, and IGF-1R) in gilthead seabream (Sparus aurata): expression and cellular localization.

S. Chan, P. Ingleton, Y. Gozes, 1999, General and comparative endocrinology.

The role of prohormone convertases in insulin biosynthesis: evidence for inherited defects in their action in man and experimental animals.

D. Steiner, Y. Rouillé, S. Chan, 1996, Diabetes & metabolism.

Messenger RNA sequence and primary structure of preproinsulin in a primitive vertebrate, the Atlantic hagfish.

D. Steiner, S. Emdin, J. Kramer, 1981, The Journal of biological chemistry.

Insulin as a cellular growth regulator.

D. Steiner, S. Terris, S. Chan, 1977, Ciba Foundation symposium.

Models of peptide biosynthesis: the molecular and cellular basis of insulin production.

D. Steiner, S. Chan, A. Rubenstein, 1986, Clinical and investigative medicine. Medecine clinique et experimentale.

Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs.

D. Steiner, B. San Segundo, S. Chan, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Biosynthesis of insulin and glucagon: a view of the current state of the art.

Å. Lernmark, D. Steiner, S. Chan, 2008, Ciba Foundation symposium.

Evolution of insulin-like growth factor-I (IGF-I) action: in vitro characterization of vertebrate IGF-I proteins.

Z. Upton, F. Ballard, S. Chan, 1998, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Nucleotide sequence and growth hormone-regulated expression of salmon insulin-like growth factor I mRNA.

D. Steiner, S. Duguay, S. Chan, 1989, Molecular endocrinology.

Loss of a restriction endonuclease cleavage site in the gene of a structurally abnormal human insulin.

D. Steiner, S. Chan, S. Kwok, 1981, Biochemical and biophysical research communications.

Direct effect of glucose on the preproinsulin mRNA level in isolated pancreatic islets.

S. Chan, J. Brunstedt, 1982, Biochemical and biophysical research communications.

Conservation of PDX-1 structure, function, and expression in zebrafish.

D. Steiner, S. Duguay, S. Chan, 1998, Endocrinology.

T-cell receptor alpha-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11).

J. Rowley, M. L. Le Beau, M. Diaz, 1986, Proceedings of the National Academy of Sciences of the United States of America.

BIOSYNTHESIS OF ISLET CELL HORMONES

D. Steiner, R. Assoian, S. Chan, 1980, Annals of the New York Academy of Sciences.

Cloning and nucleotide sequence analysis of the dog insulin gene. Coded amino acid sequence of canine preproinsulin predicts an additional C-peptide fragment.

D. Steiner, S. Chan, S. Kwok, 1983, The Journal of biological chemistry.

The expression of cathepsin B and other lysosomal proteinases in normal tissues and in tumors.

D. Steiner, S. Chan, A. S. Bajkowski, 1991, Biomedica biochimica acta.

Guinea pig preproinsulin gene: an evolutionary compromise?

D. Steiner, S. Zeitlin, S. Chan, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Altered gene structure and tissue expression of islet amyloid polypeptide in the chicken.

D. Steiner, G. Westermark, S. Chan, 1994, Molecular endocrinology.

Biosynthesis and periplasmic segregation of human proinsulin in Escherichia coli.

D. Steiner, C. Bahl, S. Chan, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequence and analysis of the mouse SPC3 promoter region

D. Steiner, S. Chan, S. J. Chan, 1994, FEBS letters.

Chemical and biological aspects of insulin and proinsulin.

D. Steiner, S. Terris, S. Chan, 1976, Acta medica Scandinavica. Supplementum.

Structure and evolution of insulin and insulin-like growth factors in chordates.

D. Steiner, S. Chan, S. Nagamatsu, 1992, Progress in brain research.

Amyloid Formation in Response to β Cell Stress Occurs In Vitro, but Not In Vivo, in Islets of Transgenic Mice Expressing Human Islet Amyloid Polypeptide

D. Steiner, P. Westermark, G. Westermark, 1995, Molecular medicine.

Transcriptional regulation of cathepsin B expression in B16 melanomas of varying metastatic potential.

D. Steiner, S. Chan, C. Achkar, 1994, Biochemical and biophysical research communications.

Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues.

D. Steiner, S. Chan, A. S. Bajkowski, 1989, Cancer research.

Molecular cloning of rat precursor cathepsin H and the expression of five lysosomal cathepsins in normal tissues and in a rat carcinosarcoma.

D. Steiner, S. Chan, F. Qian, 1990, The International journal of biochemistry.

The new enzymology of precursor processing endoproteases.

D. Steiner, S. Chan, S. J. Chan, 1992, The Journal of biological chemistry.

Cell-free synthesis of rat preproinsulins: characterization and partial amino acid sequence determination.

D. Steiner, P. Keim, S. Chan, 1976, Proceedings of the National Academy of Sciences of the United States of America.

The structure of the mouse cathepsin B gene and its putative promoter.

D. Steiner, S. Chan, S. J. Chan, 1991, DNA and cell biology.

A mutation in the B chain coding region is associated with impaired proinsulin conversion in a family with hyperproinsulinemia.

D. Steiner, P. Gruppuso, S. Chan, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Changes in the expression of elastase and cathepsin B with differentiation of U937 promonocytes by GMCSF.

R. Stockley, J. Crocker, S. Chan, 1990, Biochemical and biophysical research communications.

Localization of IGF-I and IGF-I receptor mRNA in Sparus aurata larvae.

S. Chan, S. J. Chan, B. Funkenstein, 1997, General and comparative endocrinology.

Insulin Wakayama: familial mutant insulin syndrome in Japan

K. Polonsky, D. Steiner, T. Sanke, 1987, Diabetologia.

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans.

D. Steiner, S. Chan, S. J. Chan, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the cathepsin B gene and multiple mRNAs in human tissues: evidence for alternative splicing of cathepsin B pre-mRNA.

D. Steiner, S. Chan, S. J. Chan, 1993, DNA and cell biology.

Structure of the chum salmon insulin-like growth factor I gene.

D. Steiner, C. Roberts, D. Leroith, 1993, DNA and cell biology.

Developmental and tissue-regulated expression of IGF-I and IGF-II mRNAs in Sparus aurata.

D. Steiner, S. Duguay, S. Chan, 1996, Journal of molecular endocrinology.

Recombinant gilthead seabream (Sparus aurata) insulin-like growth factor-I: subcloning, expression in Escherichia coli, purification and characterization.

T. Marchant, S. Chan, A. Gertler, 1997, The Journal of endocrinology.

Evolution of insulin-like growth factor (IGF) function: production and characterization of recombinant hagfish IGF.

D. Steiner, J. Wallace, Z. Upton, 1997, General and comparative endocrinology.

Evolution of the insulin gene superfamily. Sequence of a preproinsulin-like growth factor cDNA from the Atlantic hagfish.

D. Steiner, S. Falkmer, S. Chan, 1991, The Journal of biological chemistry.

Evolution of the insulin superfamily: cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus.

D. Steiner, S. Chan, Q. Cao, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Formation of biologically active peptides

Å. Lernmark, D. Steiner, K. Gabbay, 1980, Proceedings of the Royal Society of London. Series B. Biological Sciences.

Immunological and chemical characterization of bovine preproinsulin.

P. Lomedico, D. Steiner, G. Saunders, 1977, The Journal of biological chemistry.

PRECURSORS IN THE BIOSYNTHESIS OF INSULIN AND OTHER PEPTIDE HORMONES

D. Steiner, R. Heinrikson, P. Keim, 1979 .

BIOSYNTHESIS OF POLYPEPTIDE HORMONES IN INTACT AND CELL-FREE SYSTEMS

D. Steiner, G. Hortin, R. Heinrikson, 1978 .

The biosynthesis and processing of neuroendocrine peptides: identification of proprotein convertases involved in intravesicular processing.

D. Steiner, S. Chan, S. Smeekens, 1992, Progress in brain research.

Use of formylated yeast initiator Met tRNA to define the NH2-terminal residues of rat preproinsulin and pregrowth hormone.

D. Steiner, P. Sigler, E. Ackerman, 1981, Journal of Biological Chemistry.

Conservation of the prohormone convertase gene family in metazoa: analysis of cDNAs encoding a PC3-like protein from hydra.

H. Bode, D. Steiner, A. Oliva, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Studies on mutant human insulin genes: identification and sequence analysis of a gene encoding [SerB24]insulin.

D. Steiner, M. Haneda, S. Chan, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Identification of cDNA clones encoding a precursor of rat liver cathepsin B.

D. Steiner, B. San Segundo, S. Chan, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Expression of rat and mouse cathepsin B precursors in Escherichia coli.

D. Steiner, S. Chan, J. Mort, 1988, Biological Chemistry Hoppe-Seyler.

The Biosynthesis of Insulin: Some Genetic and Evolutionary Aspects

D. Steiner, S. Chan, S. Kwok, 1981, Diabetes Care.

A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway.

R. Hammer, D. Steiner, S. Chan, 1988, Proceedings of the National Academy of Sciences of the United States of America.