T. Owens

发表

What is microglia neurotoxicity (Not)?

K. Biber, T. Owens, E. Boddeke, 2014, Glia.

A novel microglial subset plays a key role in myelinogenesis in developing brain

A. Waisman, N. Martin, I. Holtman, 2017, The EMBO journal.

Lentiviral-mediated administration of IL-25 in the CNS induces alternative activation of microglia

G. Martino, F. Ruffini, R. Furlan, 2012, Gene Therapy.

Protective roles for myeloid cells in neuroinflammation

T. Owens, A. Wlodarczyk, R. Khorooshi, 2020, Scandinavian journal of immunology.

Regulation of cytoplasmic and vacuolar volumes by plant cells in suspension culture.

T. Owens, R. J. Poole, T Owens, 1979, Plant physiology.

Induction of experimental autoimmune encephalomyelitis in C57BL / 6 mice deficient in either the chemokine macrophage inflammatory protein‐1α or its CCR5 receptor

W. Kuziel, T. Owens, E. Tran, 2000, European journal of immunology.

Absence of miRNA-146a Differentially Alters Microglia Function and Proteome

R. Reynolds, A. Stensballe, N. Martin, 2020, Frontiers in Immunology.

The immunology of multiple sclerosis and its animal model, experimental allergic encephalomyelitis.

T. Owens, S. Sriram, S. Sriram, 1995, Neurologic clinics.

Cytokines in CNS Inflammation

T. Owens, S. Zehntner, R. D. Wheeler, 2005 .

Perivascular Spaces and the Two Steps to Neuroinflammation

I. Bechmann, B. Engelhardt, T. Owens, 2008, Journal of neuropathology and experimental neurology.

The chemokine receptor CCR2 maintains plasmacytoid dendritic cell homeostasis.

T. Owens, A. Wlodarczyk, O. Cédile, 2017, Immunology letters.

Interferon‐γ confers resistance to experimental allergic encephalomyelitis

T. Owens, M. Krakowski, 1996, European journal of immunology.

Microglia are required for astroglial toll‐like receptor 4 response and for optimal TLR2 and TLR3 response

T. Owens, T. Holm, Dina Draeby, 2012, Glia.

CD40-mediated apoptosis in murine B-lymphoma lines containing mutated p53.

T. Owens, Q. Gong, Annette Hollmann, 2002, Experimental cell research.

Statin therapy inhibits remyelination in the central nervous system.

S. Ludwin, T. Kuhlmann, J. Antel, 2009, The American journal of pathology.

An Experimental Model of Neuromyelitis Optica Spectrum Disorder–Optic Neuritis: Insights Into Disease Mechanisms

M. Wirenfeldt, T. Owens, A. Wlodarczyk, 2021, Frontiers in Neurology.

Naive T lymphocytes traffic to inflamed central nervous system, but require antigen recognition for activation

T. Owens, Michelle L. Krakowski and, 2000, European journal of immunology.

T cell antigen receptor expression by subsets of Ly-2-L3T4- (CD8-CD4-) thymocytes.

T. Owens, K. Shortman, R. Scollay, 1988, Journal of immunology.

Angiotensin II Type 1 receptor (AT1) signaling in astrocytes regulates synaptic degeneration-induced leukocyte entry to the central nervous system

T. Owens, R. Khorooshi, M. Løbner, 2011, Brain, Behavior, and Immunity.

Elevated interferon gamma expression in the central nervous system of tumour necrosis factor receptor 1‐deficient mice with experimental autoimmune encephalomyelitis

T. Owens, S. Zehntner, L. Bourbonnière, 2006, Immunology.

Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis.

T. Kuhlmann, J. Antel, T. Owens, 2006, The American journal of pathology.

Blood–brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation

R. Buist, M. D. Del Bigio, T. Owens, 2012, Fluids and Barriers of the CNS.

Immune cell entry to the CNS--a focus for immunoregulation of EAE.

T. Owens, E. Tran, M. Hassan-Zahraee, 1998, Research in immunology.

Characterization of the expression and immunogenicity of the ns4b protein of human coronavirus 229E.

F. Chagnon, J. Laliberté, P. Talbot, 1998, Canadian journal of microbiology.

Characterization of the expression and immunogenicity of the ns4b protein of human coronavirus 229E

F. Chagnon, P. Talbot, J. Laliberté, 1998 .

CD95–CD95L: can the brain learn from the immune system?

B. Becher, J. Antel, P. Barker, 1998, Trends in Neurosciences.

Inflammatory cytokines in the brain: does the CNS shape immune responses?

T. Owens, T. Renno, M. Krakowski, 1994, Immunology today.

Microglial reactivity correlates to the density and the myelination of the anterogradely degenerating axons and terminals following perforant path denervation of the mouse fascia dentata

F. Poulsen, B. Finsen, T. Owens, 1999, Neuroscience.

Syddansk Universitet CSF 1 R Stimulation Promotes Increased Neuroprotection by CD 11 c + Microglia in EAE

T. Owens, A. Wlodarczyk, A. Benmamar-Badel, 2019 .

CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE

T. Owens, A. Wlodarczyk, A. Benmamar-Badel, 2019, Front. Cell. Neurosci..

Astrogliosis in the Neonatal and Adult Murine Brain Post-Trauma: Elevation of Inflammatory Cytokines and the Lack of Requirement for Endogenous Interferon-γ

V. Yong, T. Owens, V. Balasingam, 1997, The Journal of Neuroscience.

Signaling through Intercellular Adhesion Molecule 1 (ICAM-1) in a B Cell Lymphoma Line

T. Owens, J. Holland, 1997, The Journal of Biological Chemistry.

Microglial Cell Population Expansion Following Acute Neural Injury

M. Wirenfeldt, B. Finsen, T. Owens, 2007 .

Reactive microgliosis engages distinct responses by microglial subpopulations after minor central nervous system injury

K. Lambertsen, M. Wirenfeldt, F. Dagnaes-hansen, 2005, Journal of neuroscience research.

Glutamate metabolism is down‐regulated in astrocytes during experimental allergic encephalomyelitis

T. Owens, M. Didier-Bazès, E. Tran, 1997, Glia.

CD54/intercellular adhesion molecule 1 and major histocompatibility complex II signaling induces B cells to express interleukin 2 receptors and complements help provided through CD40 ligation

T. Owens, J. Poudrier, 1994, The Journal of experimental medicine.

The role of CD4 in antigen-independent activation of isolated single T lymphocytes.

A. Kelso, T. Owens, 1988, Cellular immunology.

X-linked Inhibitor of Apoptosis Regulates T Cell Effector Function1

Stephen J. Morris, G. Robertson, J. Gillard, 2007, The Journal of Immunology.

IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines.

T. Owens, E. Tran, E. Prince, 2000, Journal of immunology.

Immune regulation and CNS autoimmune disease

J. Antel, T. Owens, 1999, Journal of Neuroimmunology.

Innate Signaling in the CNS Prevents Demyelination in a Focal EAE Model

T. Owens, A. Wlodarczyk, R. Khorooshi, 2021, Frontiers in Neuroscience.

MOG extracellular domain (p1–125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE

T. Owens, R. Khorooshi, J. T. Mony, 2014, Multiple sclerosis.

Constitutive expression of a costimulatory ligand on antigen‐presenting cells in the nervous system drives demyelinating disease

T. Owens, S. Fournier, S. Zehntner, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A Pathogenic Role for CD8+ T Cells in a Spontaneous Model of Demyelinating Disease1

T. Owens, S. Fournier, S. Zehntner, 2006, The Journal of Immunology.

Spontaneous Model of Demyelinating Disease T Cells in a + A Pathogenic Role for CD8

T. Owens, S. Fournier, S. Zehntner, 2006 .

Angiotensin AT2 receptor–induced interleukin-10 attenuates neuromyelitis optica spectrum disorder–like pathology

T. Owens, R. Khorooshi, U. Steckelings, 2019, Multiple sclerosis.

Interferons in the central nervous system: A few instruments play many tunes

T. Owens, A. Wlodarczyk, R. Khorooshi, 2014, Glia.

Neuromyelitis optica-like pathology is dependent on type I interferon response

T. Owens, A. Wlodarczyk, R. Khorooshi, 2013, Experimental Neurology.

Complement-dependent pathogenicity of brain-specific antibodies in cerebrospinal fluid

S. Lillevang, T. Owens, R. Khorooshi, 2013, Journal of Neuroimmunology.

IFNγ Enhances Microglial Reactions to Hippocampal Axonal Degeneration

B. Finsen, T. Owens, M. B. Jensen, 2000, The Journal of Neuroscience.

Superantigen presenting capacity of human astrocytes

R. Sékaly, J. Antel, T. Owens, 2000, Journal of Neuroimmunology.

Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease

T. Owens, H. Toft-hansen, L. Füchtbauer, 2011, Glia.

IFN-γ Shapes Immune Invasion of the Central Nervous System Via Regulation of Chemokines1

T. Owens, E. Tran, E. Prince, 2000, The Journal of Immunology.

Neutrophils That Infiltrate the Central Nervous System Regulate T Cell Responses1

T. Owens, C. Brickman, S. Zehntner, 2005, The Journal of Immunology.

Nervous System Regulate T Cell Responses Neutrophils That Infiltrate the Central

T. Owens, C. Brickman, S. Zehntner, 2005 .

Bone marrow-derived versus parenchymal sources of inducible nitric oxide synthase in experimental autoimmune encephalomyelitis

T. Owens, S. Zehntner, E. Tran, 2004, Journal of Neuroimmunology.

Production of two hemopoietic growth factors is differentially regulated in single T lymphocytes activated with an anti-T cell receptor antibody.

A. Kelso, T. Owens, 1988, Journal of immunology.

Autoimmune Encephalomyelitis Specific Cell Types in Experimental Key Metalloproteinases Are Expressed by

D. Edwards, T. Owens, H. Toft-hansen, 2004 .

Animal Models of Neurologic Disease

I. Campbell, T. Owens, 2005 .

Leukocyte Recruitment after Brain Injury Signaling through MyD88 Regulates

T. Owens, H. Toft-hansen, A. Babcock, 2008 .

Selected Disorders of the Endocrine and Metabolic System

Scott G. Garland, T. Owens, A. Falk, 2021, Family Medicine.

Thymic CCL2 influences induction of T-cell tolerance.

T. Owens, A. Wlodarczyk, M. Løbner, 2014, Journal of autoimmunity.

Comparison of microglia and infiltrating CD11c+ cells as antigen presenting cells for T cell proliferation and cytokine response

T. Owens, A. Wlodarczyk, M. Løbner, 2014, Journal of Neuroinflammation.

The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis

T. Owens, M. Krakowski, 1997, European journal of immunology.

T-cell costimulation: T cells themselves call the shots

T. Owens, 1996, Current Biology.

Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System

T. Owens, R. Khorooshi, 2010, The Journal of Immunology.

Central Nervous System Regulates Inflammatory Responses in the Injury-Induced Type I IFN Signaling

T. Owens, R. Khorooshi, 2010 .

Immune Functions of Microglia

T. Owens, 2012 .

CCL2 recruits T cells into the brain in a CCR2‐independent manner

T. Owens, A. Wlodarczyk, O. Cédile, 2017, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

NF-κB-Driven STAT2 and CCL2 Expression in Astrocytes in Response to Brain Injury1

T. Owens, R. Khorooshi, A. Babcock, 2008, The Journal of Immunology.

Induced IL-18 Binding Protein g and Th17 Responses Are Inhibited by IFN-Inflammation in the Central Nervous System

T. Owens, M. Løbner, Jason M Millward, 2010 .

A noncognate interaction with anti‐receptor antibody‐activated helper T cells induces small resting murine B cells to proliferate and to secrete antibody

T. Owens, 1988, European journal of immunology.

Derivation from an alloreactive T-cell line of a clone which cross-reacts with a self H2-E-restricted minor alloantigen.

T. Owens, I. N. Crispe, M. Liddell, 1984, Cellular immunology.

SARS-CoV-2 and Immunity: Natural Infection Compared with Vaccination

P. Simeone, P. Lanuti, L. Stuppia, 2022, International journal of molecular sciences.

The presentation of cell surface alloantigens to T cells.

A. Czitrom, T. Owens, N. Gascoigne, 1984, Immunobiology.

Macrophage-independent T cell infiltration to the site of injury-induced brain inflammation

N. Rooijen, T. Owens, M. Fux, 2008, Journal of Neuroimmunology.

Elevated interferon-gamma in CNS inflammatory disease: a potential complication for bone marrow reconstitution in MS

T. Owens, E. Tran, M. Hassan-Zahraee, 2000, Journal of Neuroimmunology.

Requirement for noncognate interaction with T cells for the activation of B cell immunoglobulin secretion by IL-2.

T. Owens, 1991, Cellular immunology.

Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis

S. Weiss, T. Owens, R. Khorooshi, 2015, Acta Neuropathologica.

PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis

Alan C. Evans, B. Becher, D. Reutens, 1997, Journal of neuroscience research.

A significant proportion of normal resting B cells are induced to secrete immunoglobulin through contact with anti‐receptor antibody‐activated helper T cells in clonal cultures

G. Nossal, G. Nossal, T. Owens, 1988, European Journal of Immunology.

The complex immunology of multiple sclerosis

T. Owens, 2014, Multiple sclerosis.

Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis.

T. Owens, T. Renno, R. Zeine, 1994, International immunology.

JPET #106096 1 TITLE PAGE PERIPHERAL PDE4 INHIBITION PRODUCED BY L-826,141 PREVENTS EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS

G. Robertson, J. Mancini, C. Moore, 2006 .

Peripheral Phosphodiesterase 4 Inhibition Produced by

G. Robertson, J. Mancini, C. Moore, 2006 .

Expression of Astrocytic Type 2 Angiotensin Receptor in Central Nervous System Inflammation Correlates With Blood–Brain Barrier Breakdown

T. Owens, R. Khorooshi, H. Toft-hansen, 2010, Journal of Molecular Neuroscience.

Toll-like receptors in neurodegeneration.

T. Owens, 2009, Current topics in microbiology and immunology.

Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury

R. Gregersen, M. Wirenfeldt, I. Dalmau, 2005, Glia.

Enhanced response to antigen within lymph nodes of SJL/J mice that were protected against experimental allergic encephalomyelitis by T cell vaccination

T. Owens, R. Zeine, D. Heath, 1993, Journal of Neuroimmunology.

Specific blockade by CD54 and MHC II of CD40-mediated signaling for B cell proliferation and survival.

T. Owens, I. N. Crispe, C. Hollmann, 2001, Experimental cell research.

The pathogenesis of encephalitis

B. Finsen, T. Owens, S. Fournier, 2001 .

Toll-Like Receptors in Brain Development and Homeostasis

T. Owens, P. Larsen, T. Holm, 2007, Science's STKE.

Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation.

J. Miller, B. Fazekas de St. Groth, T. Owens, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice

J. Antel, C. Piccirillo, T. Owens, 1994, Journal of Neuroimmunology.

Detection of colony‐stimulating factor messenger RNA in single T cells by in situ hybridization

M. Pearse, T. Owens, D. Williamson, 1989, Journal of cellular physiology.

ACTIVATION OF LYMPHOCYTES OF MAN AND MOUSE: MONOVALENT CATION FLUXES *

T. Owens, J. Kaplan, 1980, Annals of the New York Academy of Sciences.

The attraction of adhesion molecules

J. Antel, T. Owens, 1993, Annals of neurology.

Astrocytes in Response to Brain Injury B-Driven STAT 2 and CCL 2 Expression κ

T. Owens, R. Khorooshi, A. Babcock, 2008 .

The changing face of cytokines in the brain: perspectives from EAE.

T. Owens, R. D. Wheeler, 2005, Current pharmaceutical design.

University of Southern Denmark Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis

S. Weiss, T. Owens, R. Khorooshi, 2015 .

Syddansk Universitet Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis

S. Weiss, T. Owens, R. Khorooshi, 2015 .

The murine gammaherpesvirus-68 chemokine-binding protein M3 inhibits experimental autoimmune encephalomyelitis

J. Christensen, A. Thomsen, P. Holst, 2010, Journal of Neuroimmunology.

Loss rather than downregulation of CD4+ T cells as a mechanism for remission from experimental allergic encephalomyelitis

T. Owens, R. Zeine, 1993, Journal of Neuroimmunology.

Toll-like receptors on astrocytes: patterning for immunity

T. Owens, 2005, Journal of Neuroimmunology.

Cellular contact as a component of signaling during cognate T/B interactions.

T. Owens, 1990, Research in immunology.

The protective effect of Angiotensin AT2-receptor stimulation in Neuromyelitis optica spectrum disorder is independent of astrocyte-derived BDNF.

T. Owens, R. Khorooshi, U. Steckelings, 2021, Multiple sclerosis and related disorders.

Multiple sclerosis and immune regulatory cells.

J. Antel, T. Owens, 2004, Brain : a journal of neurology.

Protective Microglial Subset in Development, Aging, and Disease: Lessons From Transcriptomic Studies

T. Owens, A. Wlodarczyk, A. Benmamar-Badel, 2020, Frontiers in Immunology.

The enigma of multiple sclerosis: inflammation and neurodegeneration cause heterogeneous dysfunction and damage.

T. Owens, 2003, Current opinion in neurology.

Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice.

N. Van Rooijen, T. Owens, C. Dijkstra, 1998, Journal of immunology.

Chemokine Expression by Glial Cells Directs Leukocytes to Sites of Axonal Injury in the CNS

W. Kuziel, S. Rivest, T. Owens, 2003, The Journal of Neuroscience.

A specific and sensitive method for visualization of tumor necrosis factor in the murine central nervous system.

K. Lambertsen, R. Gregersen, B. Finsen, 2001, Brain research. Brain research protocols.

Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice

M. Palkovits, F. Gallyas, H. Lassmann, 2018, Front. Immunol..

Stimulation of adult oligodendrogenesis by myelin-specific T cells.

K. Lambertsen, B. Finsen, T. Owens, 2011, The American journal of pathology.

Chemokines and Autoimmune Demyelination

T. Owens, M. Fux, Jason M. Millward, 2008 .

Diffusion Kurtosis Imaging maps neural damage in the EAE model of multiple sclerosis

Brian Hansen, Andrey Chuhutin, Sune Nørhøj Jespersen, 2018, NeuroImage.

Selective localization of IgG from cerebrospinal fluid to brain parenchyma

T. Owens, R. Khorooshi, N. Asgari, 2018, Journal of Neuroinflammation.

Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination

T. Owens, R. Khorooshi, N. Asgari, 2017, Journal of Neuroinflammation.

Hypersensitivity Responses in the Central Nervous System

T. Owens, R. Khorooshi, N. Asgari, 2015, Front. Immunol..

Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation

T. Owens, A. Wlodarczyk, R. Khorooshi, 2015, Front. Immunol..

University of Southern Denmark Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation Wlodarczyk,

T. Owens, A. Wlodarczyk, R. Khorooshi, 2015 .

University of Southern Denmark Hypersensitivity Responses in the Central Nervous System

T. Owens, R. Khorooshi, N. Asgari, 2015 .

IFN-γ-Induced Chemokines Synergize with Pertussis Toxin to Promote T Cell Entry to the Central Nervous System1

J. Gauldie, I. Campbell, T. Owens, 2007, The Journal of Immunology.

Metalloproteinases Control Brain Inflammation Induced by Pertussis Toxin in Mice Overexpressing the Chemokine CCL2 in the Central Nervous System1

R. Buist, T. Owens, J. Peeling, 2006, The Journal of Immunology.

Peripheral Phosphodiesterase 4 Inhibition Produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) Prevents Experimental Autoimmune Encephalomyelitis

G. Robertson, J. Mancini, C. Moore, 2006, Journal of Pharmacology and Experimental Therapeutics.

Identification of new therapeutic targets for prevention of CNS inflammation

T. Owens, 2002, Expert opinion on therapeutic targets.

Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor‐α in the central nervous system

Moses Rodriguez, T. Owens, A. Peterson, 1997, European journal of immunology.

A Role for Interferon‐Gamma in Focal Cerebral Ischemia in Mice

K. Lambertsen, R. Gregersen, B. Clausen, 2004, Journal of neuropathology and experimental neurology.

Type I interferon‐activated microglia are critical for neuromyelitis optica pathology

M. Thomassen, I. Holtman, B. Eggen, 2020, Glia.

Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death.

T. Hudson, R. Sladek, J. Nalbantoglu, 2006, Cancer research.

Lines to CD 40-Mediated Cell Death Kinase Predisposes Diffuse Large B-Cell Lymphoma Cell Constitutive Activation of Extracellular Signal-Regulated

T. Hudson, R. Sladek, J. Nalbantoglu, 2006 .

Microglial recruitment, activation, and proliferation in response to primary demyelination.

T. Owens, S. Zehntner, A. Babcock, 2007, The American journal of pathology.

Vav‐1 expression correlates with NFκB activation and CD40‐mediated cell death in diffuse large B‐cell lymphoma cell lines

R. Sladek, A. Tzankov, S. Dirnhofer, 2010, Hematological oncology.

Immune response induction in the central nervous system.

T. Owens, A. Babcock, 2002, Frontiers in bioscience : a journal and virtual library.

T-dependent B-cell activation is signalled by an early increase in potassium influx.

T. Owens, J. Kaplan, 1982, Immunobiology.

Nogo-A is a Reliable Oligodendroglial Marker in Adult Human and Mouse CNS and in Demyelinated Lesions

W. Brück, T. Kuhlmann, T. Owens, 2007, Journal of neuropathology and experimental neurology.

Veto in vivo?

T. Owens, I. N. Crispe, 1985, Immunology today.

Syddansk Universitet Hypersensitivity Responses in the Central Nervous System

T. Owens, R. Khorooshi, N. Asgari, 2015 .

Signaling through MyD88 Regulates Leukocyte Recruitment after Brain Injury1

T. Owens, H. Toft-hansen, A. Babcock, 2008, The Journal of Immunology.

Blood–brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation

R. Buist, M. D. Del Bigio, T. Owens, 2012, Fluids and Barriers of the CNS.

IFN‐γ enhances neurogenesis in wild‐type mice and in a mouse model of Alzheimer's disease

H. Cohen, A. Nemirovsky, T. Owens, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Chemokine receptor expression by inflammatory T cells in EAE

T. Owens, R. Khorooshi, J. Mony, 2014, Front. Cell. Neurosci..

Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis

T. Owens, E. Tran, G. Verge, 1997, Journal of Neuroimmunology.

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

T. Korn, J. Huehn, T. Owens, 2017, Journal of Neuroinflammation.

Genetic models for CNS inflammation

J. Antel, H. Wekerle, T. Owens, 2001, Nature Medicine.

The cell biology of T-dependent B cell activation.

T. Owens, R. Zeine, 1989, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Microglia – Role in Immunity

T. Owens, 2016 .

Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice

T. Owens, R. Khorooshi, M. Løbner, 2011, Journal of Neuroinflammation.

Inflammation in the Central Nervous System and Th17 Responses Are Inhibited by IFN-γ–Induced IL-18 Binding Protein

T. Owens, M. Løbner, Jason M. Millward, 2010, The Journal of Immunology.

DNA strand breaks and differentiation.

T. Owens, J. GORDIN KAPLAN, 1983, Immunology today.

Direct demonstration of the infiltration of murine central nervous system by Pgp-1/CD44high CD45RBlow CD4+ T cells that induce experimental allergic encephalomyelitis

T. Owens, R. Zeine, 1992, Journal of Neuroimmunology.

Pertussis Toxin to Promote T Cell Entry to-Induced Chemokines Synergize with γ IFN-Gauldie and Trevor

J. Gauldie, I. Campbell, T. Owens, 2007 .

Neuromyelitis optica (NMO) – an autoimmune disease of the central nervous system (CNS)

K. Kyvik, S. Lillevang, T. Owens, 2011, Acta neurologica Scandinavica.

Suppressor T cells, distinct from "veto cells," are induced by alloantigen priming and mediate transferable suppression of cytotoxic T lymphocyte responses in vivo.

T. Owens, I. N. Crispe, 1985, Journal of immunology.

Co‐stimulation by anti‐immunoglobulin is required for B cell activation by CD40Llow T cells

T. Owens, J. Poudrier, 1994, European journal of immunology.

Innate immune responses in central nervous system inflammation

B. Finsen, T. Owens, 2011, FEBS letters.

Cytokine and chemokine inter-regulation in the inflamed or injured CNS

T. Owens, Jason M. Millward, H. Toft-hansen, 2005, Brain Research Reviews.

A role for adhesion molecules in contact‐dependent T help for B cells

T. Owens, 1991, European journal of immunology.

The cation pump as a switch mechanism controlling proliferation and differentiation in lymphocytes

T. Owens, J. Kaplan, 1982, Bioscience reports.

Increased cationic fluxes in stimulated lymphocytes of the mouse: response of enriched B- and T-cell subpopulations to B- and T-cell mitogens.

T. Owens, J. Kaplan, 1980, Canadian journal of biochemistry.

Surfactant Protein D Deficiency in Mice Is Associated with Hyperphagia, Altered Fat Deposition, Insulin Resistance, and Increased Basal Endotoxemia

S. Mandrup, U. Holmskov, O. Nielsen, 2012, PloS one.

Helper T cell lines to major and to minor histocompatibility antigens are equally effective in the regulation of B cell responses in vivo.

T. Owens, P. Lai, 1984, Cellular immunology.

Aβ-induced meningoencephalitis is IFN-γ-dependent and is associated with T cell-dependent clearance of Aβ in a mouse model of Alzheimer's disease

H. Weiner, V. Zota, A. Nemirovsky, 2006 .

Dynamics of oligodendrocyte responses to anterograde axonal (Wallerian) and terminal degeneration in normal and TNF‐transgenic mice

H. H. Nielsen, B. Finsen, T. Owens, 2004, Journal of neuroscience research.

Interferon-γ in Progression to Chronic Demyelination and Neurological Deficit Following Acute EAE

R. Simone, Moses Rodriguez, T. Owens, 1998, Molecular and Cellular Neuroscience.

Toll-Like Receptor 2 Signaling in Response to Brain Injury: An Innate Bridge to Neuroinflammation

R. Landmann, S. Rivest, M. Wirenfeldt, 2006, The Journal of Neuroscience.

Mitochondria–A target for attenuation of astrocyte pathology

T. Owens, R. Khorooshi, N. Asgari, 2021, Journal of Neuroimmunology.

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice.

J. Nyengaard, S. Paludan, L. Reinert, 2012, The Journal of clinical investigation.

Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells

B. Kristensen, M. Meyer, T. Owens, 2021, Stem cell reports.

Central Nervous System-Endogenous TLR7 and TLR9 Induce Different Immune Responses and Effects on Experimental Autoimmune Encephalomyelitis

M. Thomassen, T. Owens, R. Khorooshi, 2021, Frontiers in Neuroscience.

Comparison of microglia and infiltrating CD11c+ cells as antigen presenting cells for T cell proliferation and cytokine response

T. Owens, A. Wlodarczyk, M. Løbner, 2014, Journal of Neuroinflammation.

TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines.

C. Piccirillo, T. Owens, T. Renno, 1995, Journal of immunology.

Chemokine expression in GKO mice (lacking interferon-gamma) with experimental autoimmune encephalomyelitis.

R. Ransohoff, T. Owens, R M Ransohoff, 1999, Journal of neurovirology.

Chemokines in experimental autoimmune encephalomyelitis and multiple sclerosis.

T. Owens, A. Babcock, 2003, Advances in experimental medicine and biology.

CD8+ T cells in inflammatory demyelinating disease

T. Owens, H. A. Weiss, J. Millward, 2007, Journal of Neuroimmunology.

Syddansk Universitet Effectors of Th 1 and Th 17 cells act on astrocytes and augment their neuroinflammatory properties

T. Korn, J. Huehn, T. Owens, 2017 .

Innate signaling within the central nervous system recruits protective neutrophils

Christian Hansen, M. Thomassen, T. Owens, 2020, Acta Neuropathologica Communications.

Enhanced Microglial Clearance of Myelin Debris in T Cell-Infiltrated Central Nervous System

H. H. Nielsen, B. Finsen, T. Owens, 2009, Journal of neuropathology and experimental neurology.

Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease.

H. Weiner, V. Zota, A. Nemirovsky, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice

K. Lambertsen, B. Clausen, F. Dagnaes-hansen, 2007, Neuroscience.

Key Metalloproteinases Are Expressed by Specific Cell Types in Experimental Autoimmune Encephalomyelitis1

D. Edwards, T. Owens, H. Toft-hansen, 2004, The Journal of Immunology.

Axotomy-induced glial reactions in normal and cytokine transgenic mice.

F. Poulsen, B. Finsen, T. Owens, 1999, Advances in experimental medicine and biology.

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier

T. Owens, R. Khorooshi, N. Asgari, 2015, Annals of clinical and translational neurology.

Syddansk Universitet Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier

T. Owens, R. Khorooshi, N. Asgari, 2015 .

Downregulation of membrane type-matrix metalloproteinases in the inflamed or injured central nervous system

T. Owens, H. Toft-hansen, A. Babcock, 2007, Journal of Neuroinflammation.

Immunotherapy for multiple sclerosis: From theory to practice

B. Becher, J. Antel, T. Owens, 1996, Nature Medicine.

IL-18 Binding Protein Induced - g Responses Are Inhibited by IFN-Inflammation in the CNS and Th17

T. Owens, M. Løbner, R. D. Wheeler, 2010 .

IFN-gamma-induced chemokines synergize with pertussis toxin to promote T cell entry to the central nervous system.

J. Gauldie, I. Campbell, T. Owens, 2007, Journal of immunology.

Detection and cellular localization of phospho-STAT2 in the central nervous system by immunohistochemical staining.

T. Owens, R. Khorooshi, 2013, Methods in molecular biology.

Selective localization of IgG from cerebrospinal fluid to brain parenchyma

T. Owens, R. Khorooshi, N. Asgari, 2018, Journal of Neuroinflammation.

The acquisition of cytokine responsiveness by murine B cells: a role for antigen and IL-5 in the induction of IL-2 receptors.

T. Owens, J. Poudrier, 1994, Immunology.

TNFα: kill or cure for demyelinating disease?

J. Antel, B. Finsen, T. Owens, 2002, Molecular Psychiatry.

Suppression induction in vivo by a T helper clone?

T. Owens, I. Nicholas Crise, 1985, European journal of immunology.

Complement-dependent pathogenicity of brain-specific antibodies in cerebrospinal fluid

S. Lillevang, T. Owens, R. Khorooshi, 2013, Journal of Neuroimmunology.

The murine gammaherpesvirus-68 chemokine-binding protein M3 inhibits experimental autoimmune encephalomyelitis

J. Christensen, A. Thomsen, P. Holst, 2010, Journal of Neuroimmunology.

Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System

T. Owens, R. Khorooshi, Reza Khorooshi, 2010, The Journal of Immunology.

Neuromyelitis optica-like pathology is dependent on type I interferon response

T. Owens, A. Wlodarczyk, R. Khorooshi, 2013, Experimental Neurology.

Interaction in vivo between hapten-specific suppressor T cells and an in vitro cultured helper T cell line.

T. Owens, J. Miller, 1987, Journal of immunology.

Downregulation of membrane type-matrix metalloproteinases in the inflamed or injured central nervous system

T. Owens, A. Babcock, J. Millward, 2007, Journal of Neuroinflammation.

Participation of L3T4 in T cell activation in the absence of class II major histocompatibility complex antigens. Inhibition by anti-L3T4 antibodies is a function both of epitope density and mode of presentation of anti-receptor antibody.

B. Fazekas de St. Groth, T. Owens, 1987, Journal of immunology.