C. Heijnen

A. Kavelaars, Cindy T. J. van Velthoven, C. Heijnen, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Public Speaking Stress-Induced Neuroendocrine Responses and Circulating Immune Cell Redistribution in Irritable Bowel Syndrome

G. Gerken, J. Langhorst, G. Holtmann, 2006, The American Journal of Gastroenterology.

Neuroendocrine and blood pressure responses to rectal distensions in individuals with high and low visceral pain sensitivity

G. Gerken, G. Holtmann, S. Elsenbruch, 2007, Psychoneuroendocrinology.

Leukocyte glucocorticoid receptor expression and immunoregulation in veterans with and without post-traumatic stress disorder

H. Westenberg, E. Geuze, E. Vermetten, 2007, Molecular Psychiatry.

Pre-deployment differences in glucocorticoid sensitivity of leukocytes in soldiers developing symptoms of PTSD, depression or fatigue persist after return from military deployment

E. Geuze, E. Vermetten, A. Kavelaars, 2015, Psychoneuroendocrinology.

Glucocorticoid sensitivity of leukocytes predicts PTSD, depressive and fatigue symptoms after military deployment: A prospective study

E. Geuze, E. Vermetten, A. Kavelaars, 2012, Psychoneuroendocrinology.

Gender-Specific Neuroprotection by 2-Iminobiotin after Hypoxia—Ischemia in the Neonatal Rat via a Nitric Oxide Independent Pathway

F. Groenendaal, A. Kavelaars, H. Hagberg, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Mesenchymal stem cell transplantation changes the gene expression profile of the neonatal ischemic brain

A. Kavelaars, C. Heijnen, F. Bel, 2011, Brain, Behavior, and Immunity.

Increased Acute Inflammation, Leukotriene B4-Induced Chemotaxis, and Signaling in Mice Deficient for G Protein-Coupled Receptor Kinase 6

R. Lefkowitz, D. Patel, R. Premont, 2003, The Journal of Immunology.

G Protein-Coupled Receptor Kinase 2 in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

M. Caron, M. Schedlowski, A. Kavelaars, 2005, The Journal of Immunology.

G protein‐coupled receptor kinase 2 positively regulates epithelial cell migration

O. Barreiro, F. Sánchez‐Madrid, A. Kavelaars, 2008, The EMBO journal.

G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits.

C. Murga, A. Kavelaars, C. Heijnen, 2005, Molecular biology of the cell.

Reduced GRK2 level in T cells potentiates chemotaxis and signaling in response to CCL4

M. Caron, A. Kavelaars, C. Heijnen, 2004, Journal of leukocyte biology.

Chemotherapy accelerates age-related development of tauopathy and results in loss of synaptic integrity and cognitive impairment

A. Kavelaars, C. Heijnen, Angie C A Chiang, 2019, Brain, Behavior, and Immunity.

Attachment orientations and loss adjustment among bereaved spouses

C. Fagundes, C. Heijnen, K. Murdock, 2019, Psychoneuroendocrinology.

G protein–coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation‐induced sensitization to excitotoxic neurodegeneration

G. Collingridge, M. Maze, P. Gressens, 2013, Annals of neurology.

Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy

P. Dougherty, Xiaodong Cheng, A. Kavelaars, 2018, Pain.

Identification of FAM173B as a protein methyltransferase promoting chronic pain

A. M. Habib, A. Kavelaars, H. Willemen, 2018, PLoS biology.

MicroRNA-124 as a novel treatment for persistent hyperalgesia

A. Kavelaars, H. Willemen, C. Heijnen, 2012, Journal of Neuroinflammation.

Grief Symptoms Promote Inflammation During Acute Stress Among Bereaved Spouses

L. Jaremka, C. Fagundes, C. Heijnen, 2022, Psychological science.

Fatigue, depressive symptoms, and anxiety from adolescence up to young adulthood: A longitudinal study

L. Doornen, A. Kavelaars, C. Heijnen, 2011, Brain, Behavior, and Immunity.

Adequate endocrine and cardiovascular response to social stress in survivors of childhood acute lymphoblastic leukemia

J. Rotteveel, C. Heijnen, P. Hoogerbrugge, 2013, Psychoneuroendocrinology.

Reduced splenic natural killer cell activity in rats with a hyperreactive dopaminergic system

A. Cools, A. Kavelaars, C. Heijnen, 2004, Psychoneuroendocrinology.

Ventilator-induced heat shock protein 70 and cytokine mRNA expression in a model of lipopolysaccharide-induced lung inflammation

F. Plötz, C. Heijnen, B. Lachmann, 2003, Intensive Care Medicine.

Mitochondrial JNK phosphorylation as a novel therapeutic target to inhibit neuroinflammation and apoptosis after neonatal ischemic brain damage

A. Kavelaars, C. Heijnen, C. Nijboer, 2013, Neurobiology of Disease.

Inflammatory Markers and Development of Symptom Burden in Patients with Multiple Myeloma during Autologous Stem Cell Transplantation

V. Johnson, C. Cleeland, T. Mendoza, 2014, Clinical Cancer Research.

The rodent endovascular puncture model of subarachnoid hemorrhage: mechanisms of brain damage and therapeutic strategies

J. Kesecioglu, A. Kavelaars, Cindy T. J. van Velthoven, 2014, Journal of Neuroinflammation.

Autism and the immune system.

C. Heijnen, P. Treffers, C. Heijnen, 1997, Journal of child psychology and psychiatry, and allied disciplines.

Risk Factors for Childhood Overweight in Offspring of Type 1 Diabetic Women With Adequate Glycemic Control During Pregnancy

G. Visser, H. D. de Valk, C. Heijnen, 2009, Diabetes Care.

Beta-endorphin secretion by human peripheral blood mononuclear cells: regulation by glucocorticoids.

A. Kavelaars, C. Heijnen, R. Ballieux, 1990, Life sciences.

Oxidative stress decreases G protein-coupled receptor kinase 2 in lymphocytes via a calpain-dependent mechanism.

M. Schedlowski, R. Schmidt, A. Kavelaars, 2002, Molecular pharmacology.

Combination of deferoxamine and erythropoietin: Therapy for hypoxia–ischemia-induced brain injury in the neonatal rat?

F. Groenendaal, A. Kavelaars, C. Heijnen, 2009, Neuroscience Letters.

Immune System the of G Protein-Coupled Receptor Kinases in Adjuvant Arthritis Induces Down-Regulation

M. Schedlowski, R. Schmidt, A. Kavelaars, 2013 .

Taxol normalizes the impaired agonist-induced beta2-adrenoceptor internalization in splenocytes from GRK2+/- mice.

A. Kavelaars, C. Heijnen, A. Vroon, 2007, European journal of pharmacology.

Autoimmune Encephalomyelitis Multiple Sclerosis and Experimental G Protein-Coupled Receptor Kinase 2 in

M. Caron, M. Schedlowski, A. Kavelaars, 2005 .

Monocytes/Macrophages control resolution of transient inflammatory pain.

M. Mack, A. Kavelaars, H. Willemen, 2014, The journal of pain : official journal of the American Pain Society.

CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.

A. Boots, A. Kavelaars, C. Heijnen, 2005, Arthritis and rheumatism.

Neonatal glucocorticoids and the developing brain: short-term treatment with life-long consequences?

C. Heijnen, F. Bel, J. Bakker, 2001, Trends in Neurosciences.

Expression of type I insulin-like growth factor receptors on human peripheral blood mononuclear cells.

C. Heijnen, B. Zegers, A. Schuurmans, 1992, Endocrinology.

Effects of insulin-like growth factors and growth hormone on the in vitro proliferation of T lymphocytes

C. Heijnen, G. Rijkers, R. Kooijman, 1992, Journal of Neuroimmunology.

Low Endogenous G-Protein-Coupled Receptor Kinase 2 Sensitizes the Immature Brain to Hypoxia–Ischemia-Induced Gray and White Matter Damage

F. Groenendaal, A. Kavelaars, C. Heijnen, 2008, The Journal of Neuroscience.

Dynamics of mycobacterial HSP65-induced T-cell cytokine expression during oral tolerance induction in adjuvant arthritis.

W. van Eden, A. Kavelaars, R. van der Zee, 2002, Rheumatology.

Embryonic implantation: cytokines, adhesion molecules, and immune cells in establishing an implantation environment

C. Heijnen, N. Macklon, M. Mourik, 2008, Journal of leukocyte biology.

Stimulation of β2-adrenergic receptors inhibits calcineurin activity in CD4+ T cells via PKA–AKAP interaction

H. Engler, M. Schedlowski, A. Kavelaars, 2011, Brain, Behavior, and Immunity.

Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1

Yong Zhou, J. Hancock, Xiaodong Cheng, 2016, Scientific Reports.

Changes in the G-protein-coupled receptor desensitization machinery during relapsing–progressive experimental allergic encephalomyelitis

A. Kavelaars, C. Heijnen, A. Vroon, 2003, Journal of Neuroimmunology.

Critical Role of GRK2 in the Prevention of Chronic Pain

A. Kavelaars, C. Heijnen, Faiza Baameur, 2016 .

Astrocyte GRK 2 as a novel regulator of glutamate transport and brain damage

A. Kavelaars, H. Willemen, C. Heijnen, 2013 .

Astrocyte GRK2 as a novel regulator of glutamate transport and brain damage

P. Gressens, A. Kavelaars, H. Willemen, 2013, Neurobiology of Disease.

Hematopoietic G‐protein‐coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor‐knockout mice

L. Beckers, T. J. Berkel, A. Kavelaars, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

IL-1β signaling is required for mechanical allodynia induced by nerve injury and for the ensuing reduction in spinal cord neuronal GRK2

Y. Shavit, A. Kavelaars, C. Heijnen, 2008, Brain, Behavior, and Immunity.

A role for G protein‐coupled receptor kinase 2 in mechanical allodynia

S. Maier, L. Watkins, A. Kavelaars, 2007, The European journal of neuroscience.

Low GRK2 Underlies Hyperalgesic Priming by Glial Cell-Derived Neurotrophic Factor

A. Kavelaars, N. Eijkelkamp, Huijing Wang, 2018, Front. Pharmacol..

G Protein-Coupled Receptor Kinase 6 Acts as a Critical Regulator of Cytokine-Induced Hyperalgesia by Promoting Phosphatidylinositol 3-Kinase and Inhibiting p38 Signaling

R. Dantzer, K. Kelley, M. Schedlowski, 2012, Molecular Medicine.

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice

R. Premont, S. Elsenbruch, M. Schedlowski, 2007, Gut.

The importance of being receptive

A. Kavelaars, C. Heijnen, 1999, Journal of Neuroimmunology.

Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy.

P. Dougherty, A. Kavelaars, C. Heijnen, 2016, The journal of pain : official journal of the American Pain Society.

Predictors of Persistent and New-onset Fatigue in Adolescent Girls

A. Kavelaars, C. Heijnen, L. V. van Doornen, 2008, Pediatrics.

Immunoglobulin production in vitro in major depression: A pilot study on the modulating action of endogenous cortisol

H. Westenberg, J. M. Ree, C. Heijnen, 1995, Biological Psychiatry.

Noradrenaline induces phosphorylation of ERK-2 in human peripheral blood mononuclear cells after induction of α1-adrenergic receptors

A. Kavelaars, C. Heijnen, M. Pol, 2000, Journal of Neuroimmunology.

EXOGENOUS SURFACTANT RESTORES LUNG FUNCTION BUT NOT PERIPHERAL IMMUNOSUPPRESSION IN VENTILATED SURFACTANT-DEFICIENT RATS

N. Jansen, C. Heijnen, A. J. van Vught, 2006, Experimental lung research.

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain

C. Hack, A. Kavelaars, J. V. van Roon, 2016, The Journal of Neuroscience.

Hypothalamic-pituitary-adrenal axis function in survivors of childhood acute lymphoblastic leukemia and healthy controls

C. Heijnen, P. Hoogerbrugge, R. Gemke, 2012, Psychoneuroendocrinology.

Enhanced cortisol suppression in response to dexamethasone administration in traumatized veterans with and without posttraumatic stress disorder

H. Westenberg, E. Geuze, E. Vermetten, 2007, Psychoneuroendocrinology.

Cell-specific role of HDAC6 in chemotherapy-induced mechanical allodynia and loss of intraepidermal nerve fibers.

P. Matthias, Bo Peng, A. Kavelaars, 2019, Pain.

HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy

Ralph Mazitschek, A. Kavelaars, C. Heijnen, 2017, Brain, Behavior, and Immunity.

Treatment of adjuvant-induced arthritis by oral administration of mycobacterial Hsp65 during disease.

W. van Eden, A. Kavelaars, R. van der Zee, 2000, Arthritis and rheumatism.

Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer

A. Kavelaars, C. Heijnen, Ndidi-Ese Uzor, 2020, Acta Neuropathologica Communications.

Astrocytes improve neuronal health after cisplatin treatment through mitochondrial transfer

A. Kavelaars, C. Heijnen, R. Trinh, 2019, bioRxiv.

Balancing the immune system: Th1 and Th2

W. van Eden, S. Albani, B. Prakken, 2002, Annals of the rheumatic diseases.

Peripheral nerve P2 basic protein and the Guillain-Barré syndrome In vitro demonstration of P2-specific antibody-secreting cells

R. Demel, C. Heijnen, R. Ballieux, 1984, Journal of the Neurological Sciences.

5 Pain in childhood rheumatic arthritis

P. Helders, W. Kuis, A. Kavelaars, 1998 .

Heterogeneous medically unexplained symptoms and immune function

J. Houtveen, L. Doornen, A. Kavelaars, 2007, Brain, Behavior, and Immunity.

Cytokines regulate α1-adrenergic receptor mRNA expression in human monocytic cells and endothelial cells

A. Kavelaars, C. Heijnen, M. Pol, 2002, Journal of Neuroimmunology.

β 2-Adrenergic activation enhances interleukin-8 production by human monocytes

A. Kavelaars, C. Heijnen, M. Pol, 1997, Journal of Neuroimmunology.

Beta 2-adrenergic activation enhances interleukin-8 production by human monocytes.

A. Kavelaars, C. Heijnen, J. Zijlstra, 1997, Journal of neuroimmunology.

Adrenaline-induced immunological changes are altered in patients with rheumatoid arthritis.

R. Jacobs, M. Schedlowski, R. Schmidt, 2002, Rheumatology.

Inhibition of Mitochondrial p53 Accumulation by PFT-μ Prevents Cisplatin-Induced Peripheral Neuropathy

A. Kavelaars, C. Heijnen, Jiacheng Ma, 2017, Front. Mol. Neurosci..

Peripheral blood cytokine responses and disease severity in respiratory syncytial virus bronchiolitis.

L. Bont, A. Kavelaars, C. Heijnen, 1999, The European respiratory journal.

The Autonomic Nervous System and the Immune System in Juvenile Rheumatoid Arthritis

P. Helders, W. Kuis, A. Kavelaars, 1996, Brain, Behavior, and Immunity.

Altered Immune Function in Human Newborns after Prenatal Administration of Betamethasone: Enhanced Natural Killer Cell Activity and Decreased T Cell Proliferation in Cord Blood

A. Kavelaars, G. Visser, C. Heijnen, 1999, Pediatric Research.

Receptor Kinase 6 Mice Deficient for G Protein-Coupled-Induced Chemotaxis , and Signaling in 4 B Increased Acute Inflammation , Leukotriene

R. Lefkowitz, D. Patel, R. Premont, 2003 .

Dexamethasone Attenuates VEGF Expression and Inflammation but Not Barrier Dysfunction in a Murine Model of Ventilator–Induced Lung Injury

N. Jansen, A. Kavelaars, M. Schultz, 2013, PloS one.

Long-Term Functional Consequences and Ongoing Cerebral Inflammation after Subarachnoid Hemorrhage in the Rat

R. Dijkhuizen, J. Kesecioglu, Cindy T. J. van Velthoven, 2014, PloS one.

Ventilator-induced lung injury and multiple system organ failure: a critical review of facts and hypotheses

Arthur S Slutsky, F. Plötz, C. Heijnen, 2004, Intensive Care Medicine.

Neuroendocrine mediators up-regulate α1b- and α1d-adrenergic receptor subtypes in human monocytes

A. Kavelaars, C. Heijnen, M. Pol, 1999, Journal of Neuroimmunology.

Neuroendocrine mediators upregulate aand a-adrenergic receptor 1 b 1 d subtypes in human monocytes

A. Kavelaars, C. Heijnen, M. Pol, 1999 .

Functional α1-adrenergic receptors on leukocytes of patients with polyarticular juvenile rheumatoid arthritis

W. Kuis, A. Kavelaars, C. Heijnen, 1996, Journal of Neuroimmunology.

Regulation of B Cell Activity in Man: Role of T Cells

C. Heijnen, R. Ballieux, B. Zegers, 1979, Immunological reviews.

Increased visceral sensitivity to capsaicin after DSS-induced colitis in mice: spinal cord c-Fos expression and behavior.

G. Holtmann, S. Elsenbruch, M. Schedlowski, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Immunoregulatory T Cell Subpopulations in Man: Dissection by Monoclonal Antibodies and Fc‐Receptors

C. Heijnen, R. Ballieux, 1983, Immunological reviews.

Elevated plasma corticotrophin-releasing hormone levels in veterans with posttraumatic stress disorder.

H. Westenberg, E. Geuze, G. Stalla, 2008, Progress in brain research.

Development of Cerebral Gray and White Matter Injury and Cerebral Inflammation over Time after Inflammatory Perinatal Asphyxia

F. Groenendaal, C. Heijnen, C. Nijboer, 2015, Developmental Neuroscience.

Assessment of long-term safety and efficacy of intranasal mesenchymal stem cell treatment for neonatal brain injury in the mouse

A. de Bruin, A. Kavelaars, Cindy T. J. van Velthoven, 2015, Pediatric Research.

Intranasal Mesenchymal Stem Cell Treatment for Neonatal Brain Damage: Long-Term Cognitive and Sensorimotor Improvement

M. Kas, A. Kavelaars, Cindy T. J. van Velthoven, 2013, PloS one.

Beneficial Effect of Erythropoietin on Sensorimotor Function and White Matter After Hypoxia-Ischemia in Neonatal Mice

F. Groenendaal, C. Heijnen, F. Bel, 2011, Pediatric Research.

Inhibition of the JNK/AP-1 pathway reduces neuronal death and improves behavioral outcome after neonatal hypoxic–ischemic brain injury

A. Kavelaars, C. Heijnen, C. Nijboer, 2010, Brain, Behavior, and Immunity.

NF-κB inhibition after neonatal cerebral hypoxia–ischemia improves long-term motor and cognitive outcome in rats

F. Groenendaal, A. Kavelaars, C. Heijnen, 2010, Neurobiology of Disease.

Altered antigen-presentation in the induction of the in-vitro antigen-specific T helper cell function in patients with chronic granulomatous disease.

J. V. D. van der Meer, C. Heijnen, B. Zegers, 1986, Clinical and experimental immunology.

The influence of the hormonal system on pediatric rheumatic diseases.

W. Kuis, I. Chikanza, C. Heijnen, 2000, Rheumatic diseases clinics of North America.

J. Langhorst, G. Dobos, S. Elsenbruch, 2007, Psychoneuroendocrinology.

Disturbed in vitro adrenergic modulation of cytokine production in inflammatory bowel diseases in remission

G. Gerken, J. Langhorst, G. Holtmann, 2007, Journal of Neuroimmunology.

Immune and Endocrine Function in Burnout Syndrome

A. Kavelaars, C. Heijnen, L. V. van Doornen, 2006, Psychosomatic medicine.

Psychoneuroimmunology and chronic autoimmune diseases

A. Kavelaars, C. Heijnen, 2005 .

Calcineurin inhibition in splenocytes induced by pavlovian conditioning

H. Engler, M. Schedlowski, A. Kavelaars, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

T helper 2 cytokines induce preproenkephalin mRNA expression and proenkephalin A in human peripheral blood mononuclear cells

W. Kuis, A. Kavelaars, C. Heijnen, 1997, Journal of Neuroimmunology.

T cells in B cell chronic lymphocytic leukemia. II. Lack of antigen-specific T suppressor cells and their progenitors.

B. Bast, C. Heijnen, A. Bloem, 1985, Journal of immunology.

Receptor regulation in neuroendocrine–immune communication: Current knowledge and future perspectives

C. Heijnen, 2007, Brain, Behavior, and Immunity.

Presidential address Receptor regulation in neuroendocrine – immune communication : Current knowledge and future perspectives

C. Heijnen, 2006 .

GRK6 deficiency is associated with enhanced CXCR4‐mediated neutrophil chemotaxis in vitro and impaired responsiveness to G‐CSF in vivo

R. Premont, A. Kavelaars, I. Touw, 2004, Journal of leukocyte biology.

The effects of surgical stress and psychological stress on the immune function of operative cancer patients

M. Antoni, C. Heijnen, G. Pompe, 1998 .

Reduced Life Expectancy in Rats After Neonatal Dexamethasone Treatment

P. Kamphuis, A. Kavelaars, C. Heijnen, 2007, Pediatric Research.

The Neonatal Brain Is Not Protected by Osteopontin Peptide Treatment after Hypoxia-Ischemia

Cindy T. J. van Velthoven, C. Heijnen, C. Nijboer, 2015, Developmental Neuroscience.

Mechanical ventilation alters the immune response in children without lung pathology

Arthur S Slutsky, F. Plötz, C. Heijnen, 2002, Intensive Care Medicine.

Natural Reinfection with Respiratory Syncytial Virus Does Not Boost Virus-Specific T-Cell Immunity

L. Bont, A. Kavelaars, C. Heijnen, 2002, Pediatric Research.

Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuropathy and cognitive impairments

S. Kesler, Bo Peng, F. Mseeh, 2021, Pain.

rela-Infusion of Epinephrine Decreases Serum Levels of Cortisol and 17-Hydroxyprogesterone in Patients with Rheumatoid Arthritis

R. Straub, R. Jacobs, M. Schedlowski, 2005 .

Induction of β-Endorphin Secretion by Lymphocytes after Subcutaneous Administration of Corticotropin-Releasing Factor

A. Kavelaars, C. Heijnen, G. Croiset, 1990 .

The role of IL-1 in the corticotropin-releasing factor and arginine- vasopressin-induced secretion of immunoreactive beta-endorphin by human peripheral blood mononuclear cells.

A. Kavelaars, C. Heijnen, R. Ballieux, 1989, Journal of immunology.

Monocyte interleukin-12 production is inversely related to duration of respiratory failure in respiratory syncytial virus bronchiolitis.

L. Bont, A. Kavelaars, C. Heijnen, 2000, The Journal of infectious diseases.

Motivational changes that develop in a mouse model of inflammation-induced depression are independent of indoleamine 2,3 dioxygenase

R. Dantzer, A. Kavelaars, C. Heijnen, 2018, Neuropsychopharmacology.

Neonatal Dexamethasone Treatment Increases Susceptibility to Experimental Autoimmune Disease in Adult Rats1

P. Kamphuis, A. Kavelaars, C. Heijnen, 2000, The Journal of Immunology.

Production of Endothelin-1 and Reduced Blood Flow in the Rat Kidney During Lung-Injurious Mechanical Ventilation

P. Sipkema, H. Niessen, A. Versteilen, 2008, Anesthesia and analgesia.

Associations between fatigue and cellular metabolism in breast cancer patients: A longitudinal study

D. Tripathy, A. Kavelaars, C. Heijnen, 2022, Psychoneuroendocrinology.

G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia

G. Holtmann, S. Elsenbruch, M. Schedlowski, 2009, Brain, Behavior, and Immunity.

Can nerve damage disrupt neuroendocrine immune homeostasis? Leprosy as a case in point.

S. Lightman, G. Rook, C. Heijnen, 2002, Trends in immunology.

HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling

A. Kavelaars, C. Heijnen, P. Grace, 2022, The Journal of Neuroscience.

An HDAC6 inhibitor reverses chemotherapy-induced mechanical hypersensitivity via an IL-10 and macrophage dependent pathway

A. Kavelaars, C. Heijnen, Jiacheng Ma, 2021, Brain, Behavior, and Immunity.

Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-&mgr;

A. Kavelaars, C. Heijnen, C. Nijboer, 2015, Pain.

Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor Pifithrin-mu in a mouse model

A. Kavelaars, C. Heijnen, C. Nijboer, 2015, Brain, Behavior, and Immunity.

Chronic restraint stress impairs voluntary wheel running but has no effect on food-motivated behavior in mice

R. Dantzer, C. Heijnen, N. Boukelmoune, 2022, Brain, Behavior, and Immunity.

Suppressing Adjuvant Arthritis and Potentiates Oral Induction of Tolerance, 2-Adrenergic Agonist Salbutamol β The

A. Kavelaars, C. Heijnen, W. Eden, 2013 .

The β2-Adrenergic Agonist Salbutamol Potentiates Oral Induction of Tolerance, Suppressing Adjuvant Arthritis and Antigen-Specific Immunity1

W. van Eden, A. Kavelaars, R. van der Zee, 2002, The Journal of Immunology.

Antigen-Specific Immunity Suppressing Adjuvant Arthritis and Potentiates Oral Induction of Tolerance, -Adrenergic Agonist Salbutamol 2 b The

A. Kavelaars, C. Heijnen, W. Eden, 2002 .

T Cells as an Emerging Target for Chronic Pain Therapy

A. Kavelaars, C. Heijnen, G. Laumet, 2019, Front. Mol. Neurosci..

Cold Lymphocytotoxic Antibodies in Systemic Lupus erythematosus

R. Broekhuizen, H. Schuurman, C. Heijnen, 1984, Vox sanguinis.

Individual differences in behavior of inbred Lewis rats are associated with severity of joint destruction in adjuvant-induced arthritis

W. Gispen, A. Kavelaars, C. Heijnen, 2004, Brain, Behavior, and Immunity.

Localization of human antigen-specific helper and suppressor function in distinct T-cell subpopulations.

C. Heijnen, R. Ballieux, F. Gmelig-Meyling, 1979, Cellular immunology.

Co-operative T-T interactions in the human T suppressor cell circuit.

C. Heijnen, R. Ballieux, C. Heijnen, 1981, Immunology today.

A Dual Role of the NF- (cid:1) B Pathway in Neonatal Hypoxic-Ischemic Brain Damage

F. Groenendaal, M. May, A. Kavelaars, 2008 .

Selective Inhibition of Nuclear Factor-κB Activation After Hypoxia/Ischemia in Neonatal Rats Is Not Neuroprotective

F. Groenendaal, M. May, A. Kavelaars, 2006, Pediatric Research.

Substance P induces a rise in intracellular calcium concentration in human T lymphocytes in vitro: evidence of a receptor-independent mechanism

A. Kavelaars, C. Heijnen, F. Jeurissen, 1993, Journal of Neuroimmunology.

β‐Endorphin Effects on Membrane Transduction in Human Lymphocytes a

F. Chiappelli, A. Kavelaars, C. Heijnen, 1992 .

Partial Disruption of Leukocyte GRK2 Attenuates Atherosclerotic Lesion Formation and Modulates Plaque Phenotype

T. V. Berkel, A. Kavelaars, I. Bot, 2008 .

Social stress and the regulation of tumor necrosis factor-α secretion

J. Sheridan, A. Kavelaars, C. Heijnen, 2005, Brain, Behavior, and Immunity.

Interferon-β attenuates lung inflammation following experimental subarachnoid hemorrhage

R. Dijkhuizen, J. Kesecioglu, C. Heijnen, 2010, Critical care.

Interferon-b attenuates lung inflammation following experimental subarachnoid hemorrhage

R. Dijkhuizen, J. Kesecioglu, C. Heijnen, 2010 .

In vitro adrenergic modulation of cellular immune functions in experimental autoimmune encephalomyelitis

S. Elsenbruch, M. Schedlowski, A. Kavelaars, 2004, Journal of Neuroimmunology.

CD8+ T cell–derived IL-13 increases macrophage IL-10 to resolve neuropathic pain

A. Kavelaars, Susmita K. Singh, C. Heijnen, 2022, JCI insight.

Autoimmune Disease in Adult Rats Increases Susceptibility to Experimental Neonatal Dexamethasone Treatment

A. Kavelaars, C. Heijnen, J. Bakker, 2000 .

Clinical Significance of the Neuroendocrine Control of Autoimmune Processes: An Important Niche for Psychoneuroimmunologists?

N. Cohen, C. Heijnen, 1999, Brain, Behavior, and Immunity.

Long-Term Neuroprotection with 2-Iminobiotin, An Inhibitor of Neuronal and Inducible Nitric Oxide Synthase, after Cerebral Hypoxia-Ischemia in Neonatal Rats

F. Groenendaal, A. Kavelaars, C. Peeters-Scholte, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

T Cells as Guardians of Pain Resolution.

A. Kavelaars, C. Heijnen, 2021, Trends in molecular medicine.

Decreased TNF-alpha and NK activity in obsessive-compulsive disorder.

H. Westenberg, D. Denys, A. Kavelaars, 2004, Psychoneuroendocrinology.

Visceral pain and public speaking stress: Neuroendocrine and immune cell responses in healthy subjects

G. Gerken, G. Holtmann, S. Elsenbruch, 2006, Brain, Behavior, and Immunity.

The phosphorylation of the CD3 γ chain of T lymphocytes is modulated by β‐endorphin

W. Gispen, B. Eggen, A. Kavelaars, 1990 .

Tissue specific effects of the β2-adrenergic agonist salbutamol on LPS-induced IFN-γ, IL-10 and TGF-β responses in vivo

A. Kavelaars, N. Eijkelkamp, C. Heijnen, 2004, Journal of Neuroimmunology.

Resolution of inflammation-induced depression requires T lymphocytes and endogenous brain interleukin-10 signaling

R. Dantzer, A. Kavelaars, C. Heijnen, 2018, Neuropsychopharmacology.

Reduced Th2 cytokine production by sarcoidosis patients in clinical remission with chronic fatigue

P. Zanen, J. Grutters, A. Kavelaars, 2011, Brain, Behavior, and Immunity.

Long-term gender-specific effects of manipulation during pregnancy on immune and endocrine responsiveness in rat offspring

A. Kavelaars, C. Heijnen, J. Bakker, 1998, Journal of Neuroimmunology.

Angiopoietin-1 Treatment Reduces Inflammation but Does Not Prevent Ventilator-Induced Lung Injury

M. van Meurs, G. Molema, N. Jansen, 2010, PloS one.

Brain and immune system: a one-way conversation or a genuine dialogue?

C. Heijnen, R. Ballieux, 1987, Progress in brain research.

Endocrine and Immunological Responses to Acute Stress

C. Heijnen, G. Croiset, R. Binnekade, 1986 .

Effects of Selective Nitric Oxide Synthase Inhibition on IGF-1, Caspases and Cytokines in a Newborn Piglet Model of Perinatal Hypoxia-Ischaemia

Changlian Zhu, K. Blomgren, F. Groenendaal, 2002, Developmental Neuroscience.

Hypothermia and erythropoietin for neuroprotection after neonatal brain damage

F. Groenendaal, C. Heijnen, F. Bel, 2013, Pediatric Research.

Differential effects of β-endorphin on cAMP levels in human peripheral blood mononuclear cells

A. Kavelaars, C. Heijnen, R. Ballieux, 1990, Brain, Behavior, and Immunity.

Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review.

H. Westenberg, E. Geuze, E. Vermetten, 2006, Journal of psychiatric research.

Brain Hormones and the Immune System

A. Kavelaars, C. Heijnen, R. Ballieux, 1989 .

Expression of nitric oxide synthase isoforms and nitrotyrosine formation after hypoxia–ischemia in the neonatal rat brain

F. Groenendaal, A. Kavelaars, C. Heijnen, 2005, Journal of Neuroimmunology.

Inhibition of nNOS and iNOS following Hypoxia-Ischaemia Improves Long-Term Outcome but Does Not Influence the Inflammatory Response in the Neonatal Rat Brain

F. Groenendaal, C. Peeters-Scholte, C. Heijnen, 2003, Developmental Neuroscience.

Nasal administration of mesenchymal stem cells reverses chemotherapy-induced peripheral neuropathy in mice

M. Benders, Yongfu Tang, A. Kavelaars, 2020, Brain, Behavior, and Immunity.

Mechanical ventilation and multiple organ failure

F. Plötz, C. Heijnen, A. J. Vught, 2003, The Lancet.

Infusion of epinephrine decreases serum levels of cortisol and 17-hydroxyprogesterone in patients with rheumatoid arthritis.

R. Straub, R. Jacobs, M. Schedlowski, 2002, The Journal of rheumatology.

The rodent endovascular puncture model of subarachnoid hemorrhage: mechanisms of brain damage and therapeutic strategies

J. Kesecioglu, A. Kavelaars, Cindy T. J. van Velthoven, 2014, Journal of Neuroinflammation.

Pro- and anti-inflammatory cytokine patterns during and after cardiac surgery in young children

A. Kavelaars, C. Heijnen, A. J. van Vught, 1999, European Journal of Pediatrics.

Enzymehistochemical staining of Tμ lymphocytes for glycyl‐proline‐4‐methoxy‐beta‐naphthylamide‐peptidase (DAP IV)

A. Feller, C. Heijnen, R. Ballieux, 1982, British journal of haematology.

Defective T suppressor-inducer cell function in human immune deficiency virus-seropositive hemophilia patients.

C. Heijnen, J. W. Stoop, B. Zegers, 1988, Blood.

The seven vells of Immune conditioning

C. Heijnen, R. Ballieux, 1985, Behavioral and Brain Sciences.

Mild neonatal hypoxia–ischemia induces long-term motor- and cognitive impairments in mice

S. Arndt, A. Kavelaars, C. Heijnen, 2010, Brain, Behavior, and Immunity.

Therapeutic potential of genetically modified mesenchymal stem cells after neonatal hypoxic-ischemic brain damage.

A. Kavelaars, Cindy T. J. van Velthoven, H. Willemen, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Mesenchymal stem cells as a treatment for neonatal ischemic brain damage

A. Kavelaars, C. Heijnen, C. V. Velthoven, 2012, Pediatric Research.

Neuroprotective properties and mechanisms of erythropoietin in in vitro and in vivo experimental models for hypoxia/ischemia

F. Groenendaal, A. Kavelaars, C. Heijnen, 2008, Brain Research Reviews.

Pharmacological Neuroprotection after Perinatal Hypoxic-Ischemic Brain Injury

F. Groenendaal, A. Kavelaars, C. Heijnen, 2010, Current neuropharmacology.

The role and regulation of hypoxia-inducible factor-1α expression in brain development and neonatal hypoxic–ischemic brain injury

F. Groenendaal, C. Heijnen, F. Bel, 2009, Brain Research Reviews.

Detection of cervical cancer recurrence during follow-up: a multivariable comparison of 9 frequently investigated serum biomarkers.

G. Kenter, R. Zweemer, W. Veldhuis, 2013, Gynecologic oncology.

Cardiovascular follow-up at school age after perinatal glucocorticoid exposure in prematurely born children: perinatal glucocorticoid therapy and cardiovascular follow-up.

G. Visser, C. Heijnen, F. van Bel, 2008, Archives of pediatrics & adolescent medicine.

Long-term effects of perinatal glucocorticoid treatment on the heart

J. Baan, C. Heijnen, F. Bel, 2007 .

Cortisol deviations in people with burnout before and after psychotherapy: a pilot study.

M. Verbraak, G. Keijsers, C. Heijnen, 2006, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

Nasal Administration of Stem Cells: A Promising Novel Route to Treat Neonatal Ischemic Brain Damage

A. Kavelaars, C. Heijnen, F. Bel, 2010, Pediatric Research.

Inflammatory consequences of lung ischemia-reperfusion injury and low-pressure ventilation.

J. Kesecioglu, A. Kavelaars, C. Heijnen, 2009, The Journal of surgical research.

Modulation of the immune response by proopiomelanocortin derived peptides II. Influence of adrenocorticotropic hormone on the rise in intracellular free calcium concentration after T cell activation

A. Kavelaars, C. Heijnen, R. Ballieux, 1988, Brain, Behavior, and Immunity.

The High Costs of Low-Grade Inflammation: Persistent Fatigue as a Consequence of Reduced Cellular-Energy Availability and Non-adaptive Energy Expenditure

Robert Dantzer, R. Dantzer, C. Heijnen, 2018, Front. Behav. Neurosci..

Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits

P. Ray, M. Schedlowski, A. Kavelaars, 2021, Theranostics.

Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice

Frank van Bel, Annemieke Kavelaars, S. Sizonenko, 2012, Annals of neurology.

Stem cell therapy for neonatal brain injury: Perspectives and Challenges

P. Gressens, O. Baud, V. El Ghouzzi, 2011, Annals of neurology.

Oral antibiotics as a novel therapy for arthritis: evidence for a beneficial effect of intestinal Escherichia coli.

W. Harmsen, L. Akkermans, M. Visser, 2000, Arthritis and rheumatism.

FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression

O. Basak, P. Coffer, C. Heijnen, 2017, Stem cell reports.

Effects of Murine and Human Bone Marrow-Derived Mesenchymal Stem Cells on Cuprizone Induced Demyelination

A. Hoffmann, W. Baumgärtner, A. Kavelaars, 2013, PloS one.

Defect in B cell function in HTLV III/LAV positive hemophilia patients

C. Heijnen, J. W. Stoop, B. Zegers, 1987 .

Defect in B cell function in HTLV III/LAV positive hemophilia patients.

C. Heijnen, J. W. Stoop, B. Zegers, 1987, Blood.

Characterization of human T suppressor‐inducer, ‐precursor and ‐effector lymphocytes in the antigen‐specific plaque‐forming cell response

C. Heijnen, R. Ballieux, K. Pot, 1982, European journal of immunology.

The fibroblast-derived protein PI16 controls neuropathic pain

Bo Peng, A. Kavelaars, C. Heijnen, 2020, Proceedings of the National Academy of Sciences.

Immune regulation of pain: Friend and foe

A. Kavelaars, C. Heijnen, 2021, Science Translational Medicine.

Neuroimmune Interactions in Chronic Pain

L. Watkins, C. Heijnen, P. Grace, 2022 .

Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer

A. Kavelaars, C. Heijnen, Ndidi-Ese Uzor, 2020, Acta Neuropathologica Communications.

Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin

A. Kavelaars, C. Heijnen, N. Boukelmoune, 2018, Acta neuropathologica communications.

Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin

A. Kavelaars, C. Heijnen, N. Boukelmoune, 2018, Acta Neuropathologica Communications.

Repeated Mesenchymal Stem Cell Treatment after Neonatal Hypoxia–Ischemia Has Distinct Effects on Formation and Maturation of New Neurons and Oligodendrocytes Leading to Restoration of Damage, Corticospinal Motor Tract Activity, and Sensorimotor Function

A. Kavelaars, Cindy T. J. van Velthoven, C. Heijnen, 2010, The Journal of Neuroscience.

Regeneration of the ischemic brain by engineered stem cells: Fuelling endogenous repair processes

A. Kavelaars, C. Heijnen, F. Bel, 2009, Brain Research Reviews.

Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes : a role for nuclear factor-κ B and activator protein-1 in the regulation of expression of cytochrome p 450 enzyme 7 b

A. Kavelaars, C. Heijnen, A. Boots, 2015 .

Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b

A. Kavelaars, C. Heijnen, A. Boots, 2005, Arthritis research & therapy.

Maternal deprivation of rat pups increases clinical symptoms of experimental autoimmune encephalomyelitis at adult age

A. Cools, F. Sluyter, A. Kavelaars, 2002, Journal of Neuroimmunology.

Mechanisms of chemotherapy-induced behavioral toxicities

R. Dantzer, A. Kavelaars, C. Heijnen, 2015, Front. Neurosci..

Cerebral and Hepatic Inflammatory Response after Neonatal Hypoxia-Ischemia in Newborn Rats

C. Hack, A. Kavelaars, Cindy T. J. van Velthoven, 2013, Developmental Neuroscience.

Adjuvant Arthritis Induces Down-Regulation of G Protein-Coupled Receptor Kinases in the Immune System1

M. Schedlowski, R. Schmidt, A. Kavelaars, 2001, The Journal of Immunology.

Nasal administration of mesenchymal stem cells restores cisplatin-induced cognitive impairment and brain damage in mice

S. Kesler, Ho-Ling Liu, Bo Peng, 2018, Oncotarget.

Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials

Z. Ju, M. Konopleva, F. Meric-Bernstam, 2023, Nature Medicine.

Interleukin-10 resolves pain hypersensitivity induced by cisplatin by reversing sensory neuron hyperexcitability.

R. Dantzer, E. Walters, A. Kavelaars, 2020, Pain.

Beyond symptomatic relief for chemotherapy‐induced peripheral neuropathy: Targeting the source

P. Dougherty, A. Kavelaars, C. Heijnen, 2018, Cancer.

The Anti-Diabetic Drug Metformin Protects against Chemotherapy-Induced Peripheral Neuropathy in a Mouse Model

C. Cleeland, A. Kavelaars, Wenjun Zhou, 2014, PloS one.

Role of endogenous pro-enkephalin A-derived peptides in human T cell proliferation and monocyte IL-6 production

W. Kuis, A. Kavelaars, C. Heijnen, 1998, Journal of Neuroimmunology.

β‐Endorphin: Cytokine and Neuropeptide

A. Kavelaars, C. Heijnen, R. Ballieux, 1991, Immunological reviews.

Cardiopulmonary bypass and host defense functions in human beings: II. Lymphocyte function.

C. Heijnen, B. Zegers, R. Ballieux, 1985, The Annals of thoracic surgery.

Modulation of the immune response by POMC-derived peptides I. Influence on proliferation of human lymphocytes

A. Kavelaars, C. Heijnen, G. Croiset, 1987, Brain, Behavior, and Immunity.

A role for the autonomic nervous system in modulating the immune response during mild emotional stimuli.

C. Heijnen, G. Croiset, D. de Wied, 1990, Life sciences.

Expression of Preproenkephalin mRNA and Production and Secretion of Enkephalins by Human Thymocytes

A. Kavelaars, C. Heijnen, 2000, Annals of the New York Academy of Sciences.

Childhood maltreatment, subjective social status, and health disparities in bereavement

C. Fagundes, C. Heijnen, Charles E. Green, 2021, Psychoneuroendocrinology.

Neuroinflammation and Comorbidity of Pain and Depression

R. Dantzer, A. Kavelaars, C. Heijnen, 2014, Pharmacological Reviews.

Intranasally administered mesenchymal stem cells promote a regenerative niche for repair of neonatal ischemic brain injury

R. Dijkhuizen, A. Kavelaars, C. Heijnen, 2014, Experimental Neurology.

Antigen-specific helper and suppressor T cell factors in man.

C. Heijnen, R. Ballieux, 1982, Clinics in haematology.

Some Aspects of T Cell Regulation in Autoimmune Diseases

C. Heijnen, R. Ballieux, 1984 .

Autoimmune regulation of chronic pain

L. Watkins, C. Heijnen, P. Grace, 2021, Pain reports.

Exogenous surfactant attenuation of ischemia-reperfusion injury in the lung through alteration of inflammatory and apoptotic factors.

J. Kesecioglu, A. Kavelaars, C. Heijnen, 2009, The Journal of thoracic and cardiovascular surgery.

Mesenchymal Stem Cell Transplantation Attenuates Brain Injury After Neonatal Stroke

D. Ferriero, N. Derugin, A. Kavelaars, 2013, Stroke.

β2‐Adrenergic stimulation causes detachment of natural killer cells from cultured endothelium

C. Heijnen, R. Ballieux, R. Benschop, 1993, European journal of immunology.

Attachment and telomere length: more evidence for psychobiological connections between close relationships, health, and aging

S. Zilioli, C. Fagundes, C. Heijnen, 2018, Journal of Behavioral Medicine.

Increased dexamethasone sensitivity of neonatal leukocytes: different mechanisms of glucocorticoid inhibition of T cell proliferation in adult and neonatal cells

A. Kavelaars, G. Visser, C. Heijnen, 1995, European journal of immunology.

CD3+ T cells are critical for the resolution of comorbid inflammatory pain and depression-like behavior

R. Dantzer, A. Kavelaars, C. Heijnen, 2020, Neurobiology of pain.

Effects of short-term dexamethasone treatment during pregnancy on the development of the immune system and the hypothalamo-pituitary adrenal axis in the rat

A. Kavelaars, C. Heijnen, E. Schmidt, 1995, Journal of Neuroimmunology.

GRK2 levels in myeloid cells modulate adipose-liver crosstalk in high fat diet-induced obesity

M. Fresno, C. Gutiérrez‐Repiso, C. Murga, 2020, Cellular and Molecular Life Sciences.

Pifithrin-μ Prevents Cisplatin-Induced Chemobrain by Preserving Neuronal Mitochondrial Function.

R. Dantzer, A. Kavelaars, C. Heijnen, 2017, Cancer Research.

Stress induces increases in IL-6 production by leucocytes of patients with the chronic inflammatory disease juvenile rheumatoid arthritis: a putative role for α1-adrenergic receptors

W. Kuis, A. Kavelaars, C. Heijnen, 2000, Journal of Neuroimmunology.

Alleviation of paclitaxel-induced mechanical hypersensitivity and hyperalgesic priming with AMPK activators in male and female mice

A. Kavelaars, M. Burton, G. Dussor, 2019, Neurobiology of pain.

CD8+ T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain

P. Dougherty, C. Hack, A. Kavelaars, 2016, The Journal of Neuroscience.

Ventilator-Induced Lung Injury: Mechanisms and Future Therapeutic Interventions

M. Schultz, C. Heijnen, A. J. Vught, 2012 .

Cisplatin treatment induces attention deficits and impairs synaptic integrity in the prefrontal cortex in mice

T. Reyes, A. Kavelaars, C. Heijnen, 2018, Scientific Reports.

HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity

A. Kavelaars, A. Singh, C. Heijnen, 2022, Theranostics.

Reduced tumor growth, experimental metastasis formation, and angiogenesis in rats with a hyperreactive dopaminergic system

A. Cools, E. Voest, B. Ellenbroek, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Disturbed neuroendocrine-immune interactions in chronic fatigue syndrome.

W. Kuis, A. Kavelaars, C. Heijnen, 2000, The Journal of clinical endocrinology and metabolism.

Measuring Self-Reported Cancer-Related Cognitive Impairment: Recommendations from the Cancer Neuroscience Initiative Working Group.

S. Kesler, C. Heijnen, K. V. Van Dyk, 2021, Journal of the National Cancer Institute.

Predicting PTSD: Pre-existing vulnerabilities in glucocorticoid-signaling and implications for preventive interventions

E. Geuze, A. Kavelaars, M. Olff, 2013, Brain, Behavior, and Immunity.

Systemic lupus erythematosus and rheumatoid arthritis patients differ from healthy controls in their cytokine pattern after stress exposure.

D. Meyer‐Olson, R. Jacobs, M. Schedlowski, 2001, Rheumatology.

Decreased TNF-α and NK activity in obsessive-compulsive disorder

H. Westenberg, D. Denys, A. Kavelaars, 2004, Psychoneuroendocrinology.

Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: results from a randomized, double-blind, placebo-controlled trial.

R. Kahn, D. Grobbee, W. Laan, 2010, The Journal of clinical psychiatry.

Acetylsalicylic acid as an adjuvant therapy for schizophrenia

R. Kahn, D. Grobbee, W. Laan, 2006, Trials.

Longitudinal analysis of pro- and anti-inflammatory cytokine production in severely fatigued adolescents

L. Doornen, M. Schedlowski, A. Kavelaars, 2007, Brain, Behavior, and Immunity.

Effect of mild acute stress on immune cell distribution and natural killer cell activity in breast cancer patients

M. Antoni, C. Heijnen, A. Visser, 1998, Biological Psychology.

Psychoneuroimmunology and the course of breast cancer: An overview the impact of psychosocial factors on progression of breast cancer through immune and endocrine mechanisms

M. Antoni, A. Graeff, B. Garssen, 1994 .

Protein expression profiling of inflammatory mediators in human temporal lobe epilepsy reveals co-activation of multiple chemokines and cytokines

A. A. Kan, P. Gosselaar, P. V. van Rijen, 2012, Journal of Neuroinflammation.

Characterization of chronic fatigue in patients with sarcoidosis in clinical remission.

J. Grutters, C. Heijnen, O. Vogels, 2011, Chest.

Cisplatin educates CD8+ T cells to prevent and resolve chemotherapy-induced peripheral neuropathy in mice.

R. Dantzer, A. Kavelaars, C. Heijnen, 2019, Pain.

Intranasal Stem Cell Treatment as a Novel Therapy for Subarachnoid Hemorrhage.

R. Dijkhuizen, J. Kesecioglu, Cindy T. J. van Velthoven, 2018, Stem cells and development.

Metformin Prevents Cisplatin-Induced Cognitive Impairment and Brain Damage in Mice

A. Kavelaars, Wenjun Zhou, C. Heijnen, 2016, PloS one.

The effects of β‐adrenoceptor stimulation on adhesion of human natural killer cells to cultured endothelium

C. Heijnen, R. Ballieux, R. Benschop, 1994, British journal of pharmacology.

Defective expression of mononuclear cell membrane HLA antigens associated with combined immunodeficiency: impaired cellular interactions.

W. Kuis, C. Heijnen, J. W. Stoop, 1983, Birth defects original article series.

Minocycline for symptom reduction in patients with multiple myeloma during maintenance therapy: a phase II placebo-controlled randomized trial

C. Cleeland, T. Mendoza, R. Orlowski, 2021, Supportive Care in Cancer.

High nocturnal melatonin in adolescents with chronic fatigue syndrome.

W. Kuis, A. Kavelaars, C. Heijnen, 2000, The Journal of clinical endocrinology and metabolism.

Local interferon-gamma levels during respiratory syncytial virus lower respiratory tract infection are associated with disease severity.

L. Bont, A. Kavelaars, C. Heijnen, 2001, The Journal of infectious diseases.

Elevated basal cortisol levels and attenuated acth and cortisol responses to a behavioral challenge in women with metastatic breast cancer

M. Antoni, C. Heijnen, G. Pompe, 1996, Psychoneuroendocrinology.

Effects of Neonatal Dexamethasone Treatment on the Cardiovascular Stress Response of Children at School Age

J. Karemaker, A. Kavelaars, C. Heijnen, 2008, Pediatrics.

Patients with Systemic Lupus Erythematosus Differ from Healthy Controls in Their Immunological Response to Acute Psychological Stress

R. Jacobs, M. Schedlowski, R. Schmidt, 1999, Brain, Behavior, and Immunity.

Neuroendocrine mediators up-regulate alpha1b- and alpha1d-adrenergic receptor subtypes in human monocytes.

A. Kavelaars, C. Heijnen, M. van de Pol, 1999, Journal of neuroimmunology.

Severe Fatigue in Adolescents: A Common Phenomenon?

A. Kavelaars, C. Heijnen, L. V. van Doornen, 2006, Pediatrics.

GRKs and arrestins: regulators of migration and inflammation

A. Kavelaars, C. Heijnen, A. Vroon, 2006, Journal of leukocyte biology.

Bexarotene normalizes chemotherapy-induced myelin decompaction and reverses cognitive and sensorimotor deficits in mice

Jian Hu, A. Kavelaars, C. Heijnen, 2020, Acta neuropathologica communications.

Socioeconomic disparities in health: Changes in sleep quality and inflammation during bereavement

Jonathan E. Butner, D. Chirinos, Marcel A. de Dios, 2021, Comprehensive psychoneuroendocrinology.

Combined fetal inflammation and postnatal hypoxia causes myelin deficits and autism‐like behavior in a rat model of diffuse white matter injury

Annette van der Toorn, Rick M Dijkhuizen, Floris Groenendaal, 2017, Glia.

Post-inflammatory fatigue in sarcoidosis: personality profiles, psychological symptoms and stress hormones.

J. Grutters, C. Heijnen, J. V. D. van den Bosch, 2012, Journal of psychosomatic research.

Activation of human monocytes via a non-neurokinin substance P receptor that is coupled to Gi protein, calcium, phospholipase D, MAP kinase, and IL-6 production.

E. Gelfand, R. Franklin, A. Kavelaars, 1994, Journal of immunology.

Impaired neuroendocrine and immune response to acute stress in medication-naive patients with a first episode of psychosis.

H. Westenberg, R. Kahn, J. Lijmer, 2012, Schizophrenia bulletin.

The neuroimmune basis of fatigue

R. Dantzer, A. Kavelaars, S. Layé, 2014, Trends in Neurosciences.

The Reactivity of the Cardiovascular System and Immunomodulation by Catecholamines in Juvenile Chronic Arthritis

W. Kuis, A. Kavelaars, C. Heijnen, 1998, Annals of the New York Academy of Sciences.

Exosomes: A New Weapon to Treat the Central Nervous System

C. Heijnen, C. V. Velthoven, L. Braccioli, 2013, Molecular Neurobiology.

Cardiovascular and Immune Responses to Acute Psychological Stress in Young and Old Women: A Meta-Analysis

K. Matthews, J. Cacioppo, R. Geenen, 1998, Psychosomatic medicine.

Cardiovascular and metabolic outcome in 6-8 year old offspring of women with type 1 diabetes with near-optimal glycaemic control during pregnancy.

G. Visser, H. D. de Valk, C. Heijnen, 2011, Early human development.

Nasal administration of mesenchymal stem cells prevents accelerated age-related tauopathy after chemotherapy in mice

A. Kavelaars, C. Heijnen, J. Alexander, 2023, Immunity & Ageing.

Intranasal Administration of Human MSC for Ischemic Brain Injury in the Mouse: In Vitro and In Vivo Neuroregenerative Functions

A. Kavelaars, I. Slaper-Cortenbach, C. Heijnen, 2014, PloS one.

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment

A. Kavelaars, C. Heijnen, M. Jarpe, 2018, Acta neuropathologica communications.

Bilateral Molecular Changes in a Neonatal Rat Model of Unilateral Hypoxic-Ischemic Brain Damage

F. Groenendaal, A. Kavelaars, C. Heijnen, 2006, Pediatric Research.

Glucocorticoid Receptor Pathway Components Predict Posttraumatic Stress Disorder Symptom Development: A Prospective Study

Eric Vermetten, Annemieke Kavelaars, Elbert Geuze, 2012, Biological Psychiatry.

Microglial GRK2: A novel regulator of transition from acute to chronic pain

A. Kavelaars, H. Willemen, N. Eijkelkamp, 2011, Brain, Behavior, and Immunity.

Hydrogen peroxide impairs GRK2 translation via a calpain-dependent and cdk1-mediated pathway.

A. Kavelaars, C. Heijnen, C. Ribas, 2007, Cellular signalling.

(369) Cell Specific Role of HDAC6 in Chemotherapy-Induced Mechanical Allodynia and Loss of Intraepidermal Nerve Fibers

A. Kavelaars, C. Heijnen, Jiacheng Ma, 2019, The Journal of Pain.

Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis

V. de Waard, R. Koenen, C. Weber, 2011, The Journal of experimental medicine.

Spousal bereavement is associated with more pronounced ex vivo cytokine production and lower heart rate variability: Mechanisms underlying cardiovascular risk?

J. Thayer, C. Fagundes, C. Heijnen, 2018, Psychoneuroendocrinology.

Mechanisms of Neurotoxic Symptoms as a Result of Breast Cancer and Its Treatment: Considerations on the Contribution of Stress, Inflammation, and Cellular Bioenergetics

C. Heijnen, T. Lacourt, 2017, Current Breast Cancer Reports.

Sickness behavior induced by cisplatin chemotherapy and radiotherapy in a murine head and neck cancer model is associated with altered mitochondrial gene expression

R. Dantzer, K. Mason, A. Kavelaars, 2016, Behavioural Brain Research SreeTestContent1.

Gender-Dependent Pathways of Hypoxia-Ischemia-Induced Cell Death and Neuroprotection in the Immature P3 Rat

F. Groenendaal, A. Kavelaars, C. Heijnen, 2007, Developmental Neuroscience.

Executive functioning and diabetes: The role of anxious arousal and inflammation

C. Fagundes, Danny C. Duke, C. Heijnen, 2016, Psychoneuroendocrinology.

SECRETION OF ir-ACTH BY CELLS OF LYMPHOID ORIGIN: DETECTION AT THE SINGLE CELL LEVEL

A. Kavelaars, C. Heijnen, R. Ballieux, 1987 .

Monocyte IL-10 production during respiratory syncytial virus bronchiolitis is associated with recurrent wheezing in a one-year follow-up study.

L. Bont, A. Kavelaars, C. Heijnen, 2000, American journal of respiratory and critical care medicine.

Experimental Stress and Immunological Reactivity: A Closer Look at Perceived Uncontrollability

J. Brosschot, M. Olff, C. Heijnen, 1998, Psychosomatic medicine.

Clinical burnout is not reflected in the cortisol awakening response, the day-curve or the response to a low-dose dexamethasone suppression test

L. Doornen, M. Verbraak, C. Heijnen, 2006, Psychoneuroendocrinology.

E. Geuze, E. Vermetten, A. Kavelaars, 2008, Psychoneuroendocrinology.

Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis

W. J. Burk, Samuel E. Jones, Ivonne P. M. Derks, 2020, Nature Human Behaviour.

Lipopolysaccharide-induced cytokine production in obsessive–compulsive disorder and generalized social anxiety disorder

H. Westenberg, D. Denys, N. Vulink, 2010, Psychiatry Research.

TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain

D. Tweardy, A. Kavelaars, M. Kasembeli, 2021, Biochemical pharmacology.

Differences in the response to the combined DEX-CRH test between PTSD patients with and without co-morbid depressive disorder

H. Westenberg, E. Geuze, E. Vermetten, 2008, Psychoneuroendocrinology.

Relations of plasma acth and cortisol levels with the distribution and function of peripheral blood cells in response to a behavioral challenge in breast cancer: An empirical exploration by means of statistical modeling

M. Antoni, H. Duivenvoorden, C. Heijnen, 1997, International journal of behavioral medicine.

Antigen‐specific plaque‐forming cell response of human cord blood lymphocytes after in vitro stimulation by T cell‐dependent antigens

W. Kuis, C. Heijnen, R. Ballieux, 1983, European journal of immunology.

Cytokines regulate alpha(1)-adrenergic receptor mRNA expression in human monocytic cells and endothelial cells.

A. Kavelaars, C. Heijnen, M. van de Pol, 2002, Journal of neuroimmunology.

Neuro-immune, behavioral and molecular aspects of brain damage

A. Kavelaars, C. Heijnen, 2010, Brain, Behavior, and Immunity.

Antigen-specific human T cell factors. II. T cell suppressor factor: biologic properties.

C. Heijnen, R. Ballieux, F. Uytdehaag, 1981, Journal of immunology.

Alternate Pathways Preserve Tumor Necrosis Factor-&agr; Production After Nuclear Factor-&kgr;B Inhibition in Neonatal Cerebral Hypoxia–Ischemia

F. Groenendaal, A. Kavelaars, C. Heijnen, 2009, Stroke.

Mesenchymal Stem Cell Treatment for Ischemic Brain Injury

A. Kavelaars, C. Heijnen, C. V. Velthoven, 2012 .

Cytokine Production by Leukocytes of Military Personnel with Depressive Symptoms after Deployment to a Combat-Zone: A Prospective, Longitudinal Study

Eric Vermetten, Rens van de Schoot, Annemieke Kavelaars, 2011, PloS one.

Respiratory distress syndrome-associated inflammation is related to early but not late peri/intraventricular hemorrhage in preterm infants.

T. Krediet, A. Kavelaars, C. Heijnen, 2006, The Journal of pediatrics.

Neonatal corticosteroid therapy affects growth patterns in early infancy

J. Derks, E. Mulder, C. Heijnen, 2018, PloS one.

PI16 is a non-neuronal regulator of neuropathic pain

Bo Peng, A. Kavelaars, C. Heijnen, 2019, bioRxiv.

Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain

R. Dantzer, J. O'Connor, A. Kavelaars, 2017, Brain, Behavior, and Immunity.

Inflammation and fatigue in early, untreated Parkinson's Disease

J. Friedman, G. Alves, C. Fagundes, 2018, Acta neurologica Scandinavica.

Substance P receptors and signal transduction in leukocytes.

A. Kavelaars, C. Heijnen, F. Jeurissen, 1994, ImmunoMethods.

Manganese-enhanced magnetic resonance imaging of hypoxic–ischemic brain injury in the neonatal rat

Jon Skranes, Ann-Mari Brubakk, Pål Erik Goa, 2009, NeuroImage.

Neonatal glucocorticoid treatment: Long-term effects on the hypothalamus–pituitary–adrenal axis, immune system, and problem behavior in 14–17 year old adolescents

A. Kavelaars, C. Heijnen, F. Bel, 2015, Brain, Behavior, and Immunity.

A prospective study on personality and the cortisol awakening response to predict posttraumatic stress symptoms in response to military deployment.

E. Geuze, E. Vermetten, A. Kavelaars, 2011, Journal of psychiatric research.

Neonatal Dexamethasone Treatment for Chronic Lung Disease of Prematurity Alters the Hypothalamus-Pituitary-Adrenal Axis and Immune System Activity at School Age

A. Kavelaars, G. Visser, C. Heijnen, 2008, Pediatrics.

Cortisol and severe fatigue: A longitudinal study in adolescent girls

L. Coffeng, L. Doornen, A. Kavelaars, 2007, Psychoneuroendocrinology.

Experimental Social Fear: Immunological, Hormonal, and Autonomic Concomitants

N. Frijda, B. Bermond, C. Heijnen, 1996, Psychosomatic medicine.

Modulation of the immune response by emotional stress.

C. Heijnen, G. Croiset, R. Ballieux, 1987, Life sciences.

Spillover in the Spinal Dorsal Horn of NMDA Receptors and Extrasynaptic Glutamate Glutamate Transporters Prevent Excessive Activation

Bryan M. Hooks, R. Dantzer, B. M. Hooks, 2015 .

Resolution of cisplatin-induced fatigue does not require endogenous interleukin-10 in male mice

R. Dantzer, C. Taniguchi, C. Heijnen, 2023, Behavioural Brain Research.

Targeting the A3 adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice

K. Jacobson, A. Kavelaars, S. Farr, 2022, Acta neuropathologica communications.

Targeting the Meningeal Compartment to Resolve Chemobrain and Neuropathy via Nasal Delivery of Functionalized Mitochondria

Elvin Blanco, M. Schedlowski, A. Kavelaars, 2022, Advanced healthcare materials.

Effects of neonatal dexamethasone treatment on hypothalamo-pituitary adrenal axis and immune system of the rat

A. Kavelaars, C. Heijnen, E. Schmidt, 1997, Journal of Neuroimmunology.

Cytokine production as a putative biological mechanism underlying stress sensitization in high combat exposed soldiers

E. Geuze, E. Vermetten, A. Kavelaars, 2015, Psychoneuroendocrinology.

Modulation of Lymphocyte Function by Endorphins

C. Heijnen, G. Croiset, R. Ballieux, 1987, Annals of the New York Academy of Sciences.

Grief, depressive symptoms, and inflammation in the spousally bereaved

C. Fagundes, C. Heijnen, K. Murdock, 2019, Psychoneuroendocrinology.

Glucocorticoid receptor number predicts increase in amygdala activity after severe stress

G. Fernández, E. Geuze, E. Vermetten, 2012, Psychoneuroendocrinology.

Longitudinal Manganese-Enhanced Magnetic Resonance Imaging of Delayed Brain Damage after Hypoxic-Ischemic Injury in the Neonatal Rat

T. B. Pedersen, J. Skranes, A. Brubakk, 2011, Neonatology.

Short- and long-term effects of neonatal glucocorticoid therapy: is hydrocortisone an alternative to dexamethasone?

P. Kamphuis, C. Heijnen, F. Bel, 2007 .

Employment and family income in psychological and immune outcomes during bereavement

C. Fagundes, Jensine Paoletti, C. Heijnen, 2023, Psychoneuroendocrinology.

Apomorphine-Susceptible and Apomorphine-Unsusceptible Wistar Rats Differ in Their Susceptibility to Inflammatory and Infectious Diseases: A Study on Rats with Group-Specific Differences in Structure and Reactivity of Hypothalamic–Pituitary–Adrenal Axis

A. Cools, H. van Loveren, B. Ellenbroek, 1997, The Journal of Neuroscience.

GRK2: A Novel Cell-Specific Regulator of Severity and Duration of Inflammatory Pain

G. Dorn, A. Kavelaars, Cindy T. J. van Velthoven, 2010, The Journal of Neuroscience.

Monocytes express a non-neurokinin substance P receptor that is functionally coupled to MAP kinase.

E. Gelfand, R. Franklin, A. Kavelaars, 1994, Journal of immunology.

A central role for apathy in the effectiveness of interventions for cancer‐related fatigue

C. Heijnen, C. Escalante, E. Manzullo, 2020, Psycho-oncology.

Functional alpha 1-adrenergic receptors on leukocytes of patients with polyarticular juvenile rheumatoid arthritis.

W. Kuis, A. Kavelaars, J. van der Net, 1996, Journal of neuroimmunology.

Induction of beta-endorphin secretion by lymphocytes after subcutaneous administration of corticotropin-releasing factor.

A. Kavelaars, C. Heijnen, G. Croiset, 1990, Endocrinology.

Differences in Behavioral Outcome and Motor Development at School Age After Neonatal Treatment for Chronic Lung Disease with Dexamethasone versus Hydrocortisone

L. Doornen, A. Kavelaars, G. Visser, 2006, Pediatric Research.

Effect of alpha-endorphin on the antigen-induced primary antibody response of human blood B cells in vitro.

A. Kavelaars, C. Heijnen, R. Ballieux, 1986, Journal of immunology.

Cardiac Function in 7-8-Year-Old Offspring of Women with Type 1 Diabetes

F. Meijboom, G. Visser, H. D. de Valk, 2011, Experimental diabetes research.

The Impact of Mild Emotional Stress Induced by the Passive Avoidance Procedure on Immune Reactivity

C. Heijnen, G. Croiset, R. Ballieux, 1987, Annals of the New York Academy of Sciences.

Stress and the Immune System

C. Heijnen, R. Ballieux, 1987 .

G Protein – Coupled Receptor Kinase 6 Acts as a Critical Regulator of Cytokine-Induced Hyperalgesia by Promoting Phosphatidylinositol 3-Kinase and Inhibiting p 38 Signaling

R. Dantzer, K. Kelley, M. Schedlowski, 2012 .

Interferon-gamma and interleukin-6 augment the human in vitro antibody response to the Haemophilus influenzae type b polysaccharide.

J. Poolman, C. Heijnen, G. Rijkers, 1992, The Journal of infectious diseases.

In vitro induction of a Haemophilus influenzae type b polysaccharide-specific antibody response in human peripheral blood lymphocytes of individuals recently vaccinated with an oligosaccharide-protein conjugate.

J. Poolman, C. Heijnen, B. Zegers, 1991, Journal of immunology.

Flares in Patients with Systemic Lupus erythematosus Are Associated with Daily Psychological Stress

H. Heiken, M. Schedlowski, R. Schmidt, 2003, Psychotherapy and Psychosomatics.

An effort expenditure perspective on cancer-related fatigue

R. Dantzer, K. Hess, C. Heijnen, 2018, Psychoneuroendocrinology.

An Exploratory Study into the Effect of Exhausting Bicycle Exercise on Endocrine and Immune Responses in Post-Menopausal Women: Relationships between Vigour and Plasma Cortisol Concentrations and Lymphocyte Proliferation following Exercise

A. Kavelaars, C. Heijnen, N. Bernards, 2001, International journal of sports medicine.

Glucocorticoid sensitivity of immune cells in severely fatigued adolescent girls: A longitudinal study

L. Doornen, M. Schedlowski, A. Kavelaars, 2008, Psychoneuroendocrinology.

Physiological changes in GRK2 regulate CCL2‐induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium

C. Murga, A. Kavelaars, N. Eijkelkamp, 2008, Journal of neurochemistry.

The HPA-axis and immune function in burnout.

A. Kavelaars, C. Heijnen, L. V. van Doornen, 2008, Progress in brain research.

Depression, Inflammation and Tryptophan Metabolism

R. Dantzer, K. Kelley, R. McCusker, 2013 .

Targeting the p53 pathway to protect the neonatal ischemic brain

C. Culmsee, H. Hagberg, M. A. van der Kooij, 2011, Annals of neurology.

The Balance Within—The Science Connecting Health and Emotions

C. Heijnen, Cobi J. Heijnen, 2001, Brain, Behavior, and Immunity.

T-T interactions in the induction of antigen-specific human suppressor T lymphocytes in vitro.

C. Heijnen, R. Ballieux, F. Uytdehaag, 1979, Journal of immunology.

CHAPTER 16 – DISTINCT HUMAN T-CELL SUBPOPULATIONS REGULATING THE ANTIGEN-INDUCED ANTIBODY RESPONSE

C. Heijnen, R. Ballieux, F. Uytdehaag, 1979 .

CHAPTER 9 – HUMAN B-CELL ACTIVATION IN VITRO: REGULATION BY ANTIGEN-SPECIFIC HUMAN SUPPRESSOR T CELLS

C. Heijnen, R. Ballieux, C. Pot, 1979 .

Early life intervention with glucocorticoids has negative effects on motor development and neuropsychological function in 14–17year-old adolescents

L. Sonneville, A. Kavelaars, C. Heijnen, 2013, Psychoneuroendocrinology.

stress in humans cardiovascular responsiveness to acute psychological Chronic stress affects immunologic but not

R. Geenen, J. Brosschot, M. Olff, 2013 .

Effects of environmental stimuli on immunoreactivity: Further studies on passive avoidance behavior

C. Heijnen, G. Croiset, R. Ballieux, 1989, Brain, Behavior, and Immunity.

Mesenchymal stem cells attenuate MRI‐identifiable injury, protect white matter, and improve long‐term functional outcomes after neonatal focal stroke in rats

M. Wendland, D. Ferriero, N. Derugin, 2017, Journal of neuroscience research.

Delayed administration of neural stem cells after hypoxia–ischemia reduces sensorimotor deficits, cerebral lesion size, and neuroinflammation in neonatal mice

P. Coffer, C. Heijnen, C. Nijboer, 2017, Pediatric Research.

Patient–reported fatigue prior to treatment is prognostic of survival in patients with acute myeloid leukemia

A. Futreal, S. Shelburne, A. Kavelaars, 2018, Oncotarget.

Inflammation and future depressive symptoms among recently bereaved spouses

C. Fagundes, C. Heijnen, A. LeRoy, 2021, Psychoneuroendocrinology.

Emotion regulation and immune functioning during grief: testing the role of expressive suppression and cognitive reappraisal in inflammation among recently bereaved spouses.

Bryan T. Denny, Richard B. Lopez, C. Fagundes, 2019, Psychosomatic medicine.

Role and modulation of G protein-coupled receptor signaling in inflammatory processes.

A. Kavelaars, C. Heijnen, M. S. Lombardi, 2002, Critical reviews in immunology.

Type D Personality, Temperament, and Mental Health in Military Personnel Awaiting Deployment

J. Denollet, E. Geuze, E. Vermetten, 2011, International journal of behavioral medicine.

Changes in innate and acquired immune responses in mice with targeted deletion of the dopamine transporter gene

A. Kavelaars, C. Heijnen, M. Teunis, 2005, Journal of Neuroimmunology.

Associations of meaning of illness with psychosocial, clinical, and immunological characteristics in patients with Leptomeningeal metastasis

M. Gilbert, C. Fagundes, Jimin Wu, 2021, Comprehensive psychoneuroendocrinology.

MicroRNA-124 as a novel treatment for persistent hyperalgesia

A. Kavelaars, H. Willemen, C. Heijnen, 2012, Journal of Neuroinflammation.

Fibroblast-derived PI16 sustains inflammatory pain via regulation of CD206+ myeloid cells

A. Kavelaars, C. Heijnen, A. Shepherd, 2023, Brain, Behavior, and Immunity.

MODULATION OF NATURAL KILLER (NK) CELL ACTIVITY BY MET-ENKEPHALIN IN CULTURE

C. Heijnen, R. Ballieux, R. Bolhuis, 1987 .

Stress, genetics, and immunity

A. Kavelaars, C. Heijnen, 2006, Brain, Behavior, and Immunity.

Social stress and the regulation of tumor necrosis factor-alpha secretion.

J. Sheridan, A. Kavelaars, C. Heijnen, 2005, Brain, behavior, and immunity.

Corticotropin-Releasing Hormone and Proopiomelanocortin-Derived Peptides in the Modulation of Immune Function

A. Kavelaars, C. Heijnen, R. Ballieux, 1991 .

Neonatal dexamethasone treatment induces long-lasting changes in T-cell receptor Vβ repertoire in rats

P. Kamphuis, A. Kavelaars, C. Heijnen, 2001, Journal of Neuroimmunology.

Tumor angiogenesis and metastasis formation are associated with individual differences in behavior of inbred Lewis rats

W. Gispen, A. Kavelaars, C. Heijnen, 2004, Brain, Behavior, and Immunity.

The contribution of neuroendocrine substances to the immune response.

A. Kavelaars, C. Heijnen, 1991, The Netherlands journal of medicine.

Influence of life stress on immunological reactivity to mild psychological stress.

J. Brosschot, M. Olff, G. Godaert, 1994, Psychosomatic medicine.

A Dual Role of the NF-&kgr;B Pathway in Neonatal Hypoxic-Ischemic Brain Damage

F. Groenendaal, M. May, A. Kavelaars, 2008, Stroke.

Down‐regulation of GRK2 after oxygen and glucose deprivation in rat hippocampal slices: role of the PI3‐kinase pathway

A. Kavelaars, C. Heijnen, A. Vroon, 2007, Journal of neurochemistry.

Hypoxia/Ischemia Modulates G Protein–Coupled Receptor Kinase 2 and &bgr;-Arrestin-1 Levels in the Neonatal Rat Brain

F. Groenendaal, A. Kavelaars, C. Heijnen, 2004, Stroke.

Functional analysis of the defective T cell regulation of the antigen-specific PFC response in SLE patients: differentiation of suppressor precursor cells to suppressor effector cells.

H. Kluin-Nelemans, C. Heijnen, R. Ballieux, 1982, Clinical and Experimental Immunology.

Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis

Ivonne P. M. Derks, O. Franco, A. Luik, 2020, Nature Human Behaviour.

Who Believes in “Communication”? Norman Cousins Lecture 1999

C. Heijnen, 2000, Brain, Behavior, and Immunity.

Associations of inflammation with symptom burden in patients with acute myeloid leukemia

A. Futreal, S. Shelburne, A. Kavelaars, 2018, Psychoneuroendocrinology.

Stem cells in pediatrics: state of the art and future perspectives

O. Witt, A. Kulozik, C. Heijnen, 2012, Pediatric Research.

Influence Of α-Endorphin on the Antigen-Induced PFC Response of Human Blood B Lymphocytes in Vitro

C. Heijnen, R. Ballieux, N. D. Fouw, 1986 .

Interaction Between the Central Nervous System and the Immune System: The Influence of a Short and Mild Emotional Stress on the Proliferative Response of Rat Spleen Cells

C. Heijnen, G. Croiset, R. Ballieux, 1986 .

Intranasally Administered MSC-Derived Extracellular Vesicles Reverse Cisplatin-Induced Cognitive Impairment

E. Shpall, C. Heijnen, B. Milutinovic, 2023, International journal of molecular sciences.

A longitudinal study on cortisol and complaint reduction in burnout

L. Doornen, M. Verbraak, C. Heijnen, 2006, Psychoneuroendocrinology.

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment

A. Kavelaars, C. Heijnen, M. Jarpe, 2018, Acta Neuropathologica Communications.

Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy.

P. McEwan, C. Heijnen, J. Barker, 2023, Journal of medicinal chemistry.

β‐Endorphin 1–17 Modulates High Affinity IL‐2 Receptor Expression on Human T Cells

A. Kavelaars, C. Heijnen, A. Beetsma, 1992 .

Cell-specific roles of GRK2 in onset and severity of hypoxic-ischemic brain damage in neonatal mice

G. Dorn, F. Groenendaal, A. Kavelaars, 2010, Brain, Behavior, and Immunity.

Inflammatory Markers and Development of Symptom Burden in Patients with Multiple Myeloma during Autologous Stem Cell Transplantation

V. Johnson, C. Cleeland, T. Mendoza, 2014, Clinical Cancer Research.

Ventilator-Induced Lung Injury: Mechanisms and Future Therapeutic Interventions

M. Schultz, C. Heijnen, A. J. Vught, 2012 .

A. Kavelaars, Cindy T. J. van Velthoven, C. Heijnen, 2010, The Journal of Neuroscience.

Tonic Meningeal Interleukin-10 Upregulates Delta Opioid Receptor to Prevent Relapse to Pain

R. Dantzer, A. Kavelaars, C. Heijnen, 2023, bioRxiv.

Pifithrin-μ Prevents Cisplatin-Induced Chemobrain by Preserving Neuronal Mitochondrial Function.

R. Dantzer, A. Kavelaars, C. Heijnen, 2017, Cancer research.

G Protein-Coupled Receptor Kinase 6 Acts as a Critical Regulator of Cytokine-Induced Hyperalgesia by Promoting Phosphatidylinositol 3-Kinase and Inhibiting p38 Signaling

R. Dantzer, K. Kelley, M. Schedlowski, 2012, Molecular medicine.

E. Geuze, E. Vermetten, A. Kavelaars, 2009, Brain, Behavior, and Immunity.

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice

R. Premont, S. Elsenbruch, M. Schedlowski, 2007, Gut.

G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia

G. Holtmann, S. Elsenbruch, M. Schedlowski, 2009, Brain, Behavior, and Immunity.

Fatigue, depressive symptoms, and anxiety from adolescence up to young adulthood: A longitudinal study

L. Doornen, A. Kavelaars, C. Heijnen, 2011, Brain, Behavior, and Immunity.

Chemotherapy accelerates age-related development of tauopathy and results in loss of synaptic integrity and cognitive impairment

A. Kavelaars, C. Heijnen, Angie C A Chiang, 2019, Brain, Behavior, and Immunity.

Inflammation alters motivational processes in mice independently of its ability to activate indoleamine 2,3-dioxygenase

R. Dantzer, A. Kavelaars, C. Heijnen, 2017, Brain, Behavior, and Immunity.

109. Pifithrin-μ prevents paclitaxel-induced peripheral neuropathy in a mouse model

A. Kavelaars, M. Ozcan, C. Heijnen, 2014, Brain, Behavior, and Immunity.

Peripheral blood cytokine responses and disease severity in respiratory syncytial virus bronchiolitis.

L. Bont, A. Kavelaars, C. Heijnen, 1999, The European respiratory journal.

Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b

A. Kavelaars, C. Heijnen, A. Boots, 2005, Arthritis research & therapy.

Ventilator-Induced Lung Injury: Mechanisms and Future Therapeutic Interventions

M. Schultz, C. Heijnen, A. J. Vught, 2012 .

Cytokine production as a putative biological mechanism underlying stress sensitization in high combat exposed soldiers

E. Geuze, E. Vermetten, A. Kavelaars, 2015, Psychoneuroendocrinology.

CONCISE COMMUNICATION Local Interferon- g Levels during Respiratory Syncytial Virus Lower Respiratory Tract Infection Are Associated with Disease Severity

L. Bont, A. Kavelaars, C. Heijnen, 2001 .

Chronic stress affects immunologic but not cardiovascular responsiveness to acute psychological stress in humans.

R. Geenen, J. Brosschot, M. Olff, 1994, The American journal of physiology.

Effects of neonatal dexamethasone treatment on hypothalamo-pituitary adrenal axis and immune system of the rat

A. Kavelaars, C. Heijnen, E. Schmidt, 1997, Journal of Neuroimmunology.

HUMAN B CELL ACTIVATION IN VITRO: ANTIGEN-SPECIFIC HELPER AND SUPPRESSOR EFFECTS ARE MEDIATED BY DISTINCT T CELL SUBPOPULATIONS

C. Heijnen, R. Ballieux, F. Uytdehaag, 1979 .

Antigen-Specific Immunity Suppressing Adjuvant Arthritis and Potentiates Oral Induction of Tolerance, -Adrenergic Agonist Salbutamol 2 b The

A. Kavelaars, C. Heijnen, W. Eden, 2002 .

Type D Personality, Temperament, and Mental Health in Military Personnel Awaiting Deployment

E. Geuze, A. Kavelaars, C. Heijnen, 2010, International journal of behavioral medicine.