D. Akey

发表

Structural basis for macrolactonization by the pikromycin thioesterase

Janet L. Smith, D. Sherman, D. Akey, 2006, Nature chemical biology.

Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing

Paul D. Adams, Thomas C. Terwilliger, Peter H. Zwart, 2016, Acta crystallographica. Section D, Structural biology.

Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal

Thomas C Terwilliger, Paul D Adams, Peter H Zwart, 2016, Acta crystallographica. Section D, Structural biology.

A 7 µm mini-beam improves diffraction data from small or imperfect crystals of macromolecules

Stephen Corcoran, Shenglan Xu, Michael Becker, 2008, Acta crystallographica. Section D, Biological crystallography.

A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.

Janet L. Smith, D. Sherman, S. Bernard, 2011, Journal of molecular biology.

Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization.

T. Cover, D. Lacy, M. Ohi, 2019, Journal of molecular biology.

The oligomeric state of CtBP determines its role as a transcriptional co‐activator and co‐repressor of Wingless targets

Jinhee L. Chang, K. Cadigan, Chandan Bhambhani, 2011, The EMBO journal.

Structure‐guided insights on the role of NS1 in flavivirus infection

R. Kuhn, Janet L. Smith, W. C. Brown, 2015, BioEssays : news and reviews in molecular, cellular and developmental biology.

Insights from the sea: structural biology of marine polyketide synthases.

Janet L. Smith, D. Akey, D. Khare, 2012, Natural product reports.

Structural Analysis of Helicobacter pylori VacA Reveals Insights into Oligomerization

T. Cover, D. Lacy, M. Ohi, 2019, Microscopy and Microanalysis.

Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction

S. Elledge, E. Harris, Janet L. Smith, 2021, Science.

Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.

Janet L. Smith, D. Sherman, D. Akey, 2010, Angewandte Chemie.

Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway.

David H Sherman, William H Gerwick, W. Gerwick, 2010, Structure.

Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.

Janet L. Smith, G. Chlipala, D. Sherman, 2012, Journal of the American Chemical Society.

A general scheme for synthesis of substrate-based polyketide labels for acyl carrier proteins.

Janet L. Smith, D. Akey, R. Fecik, 2010, Bioorganic & medicinal chemistry letters.

Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

G. Skiniotis, R. Kuhn, James Delproposto, 2014, Science.

Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 Å

J. Berger, D. Akey, 2005, Protein science : a publication of the Protein Society.

Extended surface for membrane association in Zika virus NS1 structure

Georgios Skiniotis, Richard J Kuhn, G. Skiniotis, 2016, Nature Structural &Molecular Biology.

Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis

J. Berger, C. Bertozzi, C. Petzold, 2004, Nature Structural &Molecular Biology.

Crystal Structure and Nonhomologous End-joining Function of the Ligase Component of Mycobacterium DNA Ligase D*

J. Berger, M. Glickman, S. Shuman, 2006, Journal of Biological Chemistry.

Thiosulfate sulfurtransferase-like domain–containing 1 protein interacts with thioredoxin

E. Fearon, R. Banerjee, Janet L. Smith, 2018, The Journal of Biological Chemistry.

The MukF subunit of Escherichia coli condensin: architecture and functional relationship to kleisins

J. Berger, S. Gradia, D. Akey, 2005, The EMBO journal.

Buried polar residues in coiled-coil interfaces.

P S Kim, P. S. Kim, V. Malashkevich, 2001, Biochemistry.

Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels

Janet L. Smith, D. Sherman, D. Akey, 2006, Nature chemical biology.

Dengue Type2 Virus Non-structural protein 1 (NS1) Form 1 crystal

J. L. Smith, D. Akey, 2014 .

Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases.

Janet L. Smith, D. Sherman, S. Bernard, 2015, ACS chemical biology.

Flavivirus NS 1 crystal structures reveal a surface for membrane association and regions of interaction with the immune system

G. Skiniotis, R. Kuhn, James Delproposto, 2014 .

Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway*

Janet L. Smith, D. Akey, H. Claxton, 2009, Journal of Biological Chemistry.

Context-Dependent Cleavage of the Capsid Protein by the West Nile Virus Protease Modulates the Efficiency of Virus Assembly

T. Pierson, Janet L. Smith, D. Akey, 2015, Journal of Virology.

Efficient merging of data from multiple samples for determination of anomalous substructure

T. Terwilliger, Janet L. Smith, D. Akey, 2016, Acta crystallographica. Section D, Structural biology.

Use of massively multiple merged data for low-resolution S-SAD phasing and refinement of flavivirus NS1.

Janet L. Smith, C. Ogata, D. Akey, 2014, Acta crystallographica. Section D, Biological crystallography.

A 7 m m mini-beam improves diffraction data from small or imperfect crystals of macromolecules

R. Sanishvili, Shenglan Xu, M. Becker, 2008 .

Structure of a modular polyketide synthase reducing region.

Janet L. Smith, D. Sherman, D. Akey, 2023, Structure.

Insights from the sea: structural biology of marine polyketide synthases.

Janet L. Smith, D. Akey, D. Khare, 2012, Natural product reports.

Use of massively multiple merged data for low-resolution S-SAD phasing and refinement of flavivirus NS1.

Janet L. Smith, C. Ogata, D. Akey, 2014, Acta crystallographica. Section D, Biological crystallography.