D. Ohman

发表

Degradation and synthesis kinetics of quorum-sensing autoinducer in Pseudomonas aeruginosa cultivation.

L. Ju, S. Suh, Chun-Chiang Chen, 2005, Journal of biotechnology.

Construction and characterization of Pseudomonas aeruginosa algB mutants: role of algB in high-level production of alginate

J. Goldberg, D. Ohman, 1987, Journal of bacteriology.

Cloning of Pseudomonas aeruginosa algG, which controls alginate structure

C. Chitnis, D. Ohman, 1990, Journal of bacteriology.

Pseudomonas aeruginosa AlgB, a two-component response regulator of the NtrC family, is required for algD transcription

D. Wozniak, D. Ohman, 1991, Journal of bacteriology.

Genetic analysis of the alginate biosynthetic gene cluster of Pseudomonas aeruginosa shows evidence of an operonic structure

C. Chitnis, D. Ohman, 1993, Molecular microbiology.

Characterization of the Pseudomonas aeruginosa alginate lyase gene (algL): cloning, sequencing, and expression in Escherichia coli

S. Monday, D. Ohman, N. Schiller, 1993, Journal of bacteriology.

Identification of algF in the alginate biosynthetic gene cluster of Pseudomonas aeruginosa which is required for alginate acetylation

M. Franklin, D. Ohman, Michael J. Franklin, 1993, Journal of bacteriology.

Pseudomonas aeruginosa AlgG is a polymer level alginate C5-mannuronan epimerase

C. Chitnis, D. White, M. Franklin, 1994, Journal of bacteriology.

Identification of algI and algJ in the Pseudomonas aeruginosa alginate biosynthetic gene cluster which are required for alginate O acetylation

M. Franklin, D. Ohman, Michael J. Franklin, 1996, Journal of bacteriology.

Deletion of algK in Mucoid Pseudomonas aeruginosa Blocks Alginate Polymer Formation and Results in Uronic Acid Secretion

D. Ohman, Sumita A. Jain, 1998, Journal of bacteriology.

Characterization of algG encoding C5-epimerase in the alginate biosynthetic gene cluster of Pseudomonas fluorescens.

K. Mathee, M. Franklin, D. Ohman, 2001, Gene.

Mutant Analysis and Cellular Localization of the AlgI, AlgJ, and AlgF Proteins Required for O Acetylation of Alginate in Pseudomonas aeruginosa

M. Franklin, D. Ohman, 2002, Journal of bacteriology.

The Pseudomonas fluorescens AlgG Protein, but Not Its Mannuronan C-5-Epimerase Activity, Is Needed for Alginate Polymer Formation

H. Ertesvåg, T. Ellingsen, S. Valla, 2003, Journal of bacteriology.

The dual roles of AlgG in C‐5‐epimerization and secretion of alginate polymers in Pseudomonas aeruginosa

H. Ertesvåg, S. Valla, M. Franklin, 2003, Molecular microbiology.

Role of an Alginate Lyase for Alginate Transport in Mucoid Pseudomonas aeruginosa

D. Ohman, Sumita A. Jain, 2005, Infection and Immunity.

Membrane topology and roles of Pseudomonas aeruginosa Alg8 and Alg44 in alginate polymerization.

D. Ohman, Sumita A. Jain, Lashanda L Oglesby, 2008, Microbiology.

Evidence for Two Promoters Internal to the Alginate Biosynthesis Operon in Pseudomonas aeruginosa

D. Ohman, J. Paletta, 2012, Current Microbiology.

Identification of Genes in the σ22 Regulon of Pseudomonas aeruginosa Required for Cell Envelope Homeostasis in Either the Planktonic or the Sessile Mode of Growth

D. Ohman, Lynn F. Wood, 2012, mBio.

Highly effective contact antimicrobial surfaces via polymer surface modifiers.

K. Wynne, D. Ohman, Lynn F. Wood, 2007, Langmuir : the ACS journal of surfaces and colloids.

FimH family of type 1 fimbrial adhesins: functional heterogeneity due to minor sequence variations among fimH genes

E. Sokurenko, D. Ohman, P. Klemm, 1994, Journal of bacteriology.

Gut-Derived Sepsis Occurs When the Right Pathogen With the Right Virulence Genes Meets the Right Host: Evidence for In Vivo Virulence Expression in Pseudomonas aeruginosa

J. Alverdy, E. Chang, M. Musch, 2000, Annals of surgery.

Characterization of the human immune response to a Pseudomonas aeruginosa O-polysaccharide-toxin A conjugate vaccine.

S. Cryz, J. Sadoff, D. Ohman, 1988, The Journal of laboratory and clinical medicine.

AlgK is a TPR-containing protein and the periplasmic component of a novel exopolysaccharide secretin.

Carrie-Lynn Keiski, L. Burrows, P. Howell, 2010, Structure.

Transcriptional and translational analyses of recA mutant alleles in Pseudomonas aeruginosa

D. Ohman, J. M. Horn, 1988, Journal of bacteriology.

Corneal infections in mice with toxin A and elastase mutants of Pseudomonas aeruginosa.

B. Iglewski, D. Ohman, R. Burns, 1980, The Journal of infectious diseases.

A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production.

S. Molin, A. Kharazmi, C. Koh, 2012, Gene.

Response of Pseudomonas aeruginosa to pyocyanin: mechanisms of resistance, antioxidant defenses, and demonstration of a manganese-cofactored superoxide dismutase

D. Hassett, D. Ohman, M. Cohen, 1992, Infection and immunity.

Identification of Critical Residues in the Propeptide of LasA Protease of Pseudomonas aeruginosa Involved in the Formation of a Stable Mature Protease

D. Ohman, E. Kessler, J. Gustin, 2007, Journal of bacteriology.

Bio-inspired chemical reactors for growing aligned gold nanoparticle-like wires.

Zhe-Xue Lu, D. Ohman, Lynn F. Wood, 2009, Chemical communications.

The anti-sigma factor MucA of Pseudomonas aeruginosa: Dramatic differences of a mucA22 vs. a ΔmucA mutant in anaerobic acidified nitrite sensitivity of planktonic and biofilm bacteria in vitro and during chronic murine lung infection

Boo Shan Tseng, L. Lu, Shengchang Su, 2019, PloS one.

Isolation and characterization of Pseudomonas aeruginosa PAO mutant that produces altered elastase

S. Cryz, B. Iglewski, D. Ohman, 1980, Journal of bacteriology.

Posttranslational control of the algT (algU)-encoded sigma22 for expression of the alginate regulon in Pseudomonas aeruginosa and localization of its antagonist proteins MucA and MucB (AlgN)

K. Mathee, D. Ohman, D E Ohman, 1997, Journal of bacteriology.

Alginate production affects Pseudomonas aeruginosa biofilm development and architecture, but is not essential for biofilm formation.

S. Molin, A. Kharazmi, G. Narasimhan, 2004, Journal of medical microbiology.

Role of Alginate O Acetylation in Resistance of Mucoid Pseudomonas aeruginosa to Opsonic Phagocytosis

G. Pier, M. Franklin, F. Coleman, 2001, Infection and Immunity.

Cloning and expression in Pseudomonas aeruginosa of a gene involved in the production of alginate

J. Goldberg, D. Ohman, 1984, Journal of bacteriology.

Pseudomonas aeruginosa sodA and sodB mutants defective in manganese- and iron-cofactored superoxide dismutase activity demonstrate the importance of the iron-cofactored form in aerobic metabolism

D. Hassett, H. Schweizer, D. Ohman, 1995, Journal of bacteriology.

Real-Time Observation of Antimicrobial Polycation Effects on Escherichia coli: Adapting the Carpet Model for Membrane Disruption to Quaternary Copolyoxetanes.

V. Yadavalli, K. Wynne, Congzhou Wang, 2016, Langmuir : the ACS journal of surfaces and colloids.

Structural and Functional Characterization of Pseudomonas aeruginosa AlgX

P. Howell, H. Robinson, Perrin Baker, 2013, The Journal of Biological Chemistry.

Inhibitors and Specificity of Pseudomonas aeruginosa LasA*

J. Rosenbloom, D. Ohman, E. Kessler, 1997, The Journal of Biological Chemistry.

Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections

J. Goldberg, G. Pier, M. Preston, 1997, Infection and immunity.

Development of tools for the genetic manipulation of Pseudomonas aeruginosa.

S. Suh, D. Ohman, L. Silo-suh, 2004, Journal of microbiological methods.

Functional Fluorous Copolyoxetane Polymer Surface Modifiers

Tomoko Fujiwara, K. Wynne, A. Chakravorty, 2014 .

Surface Characterization, Antimicrobial Effectiveness, and Human Cell Response for a Biomedical Grade Polyurethane Blended with a Mixed Soft Block PTMO-Quat/PEG Copolyoxetane Polyurethane.

X. Wen, Chenyu Wang, K. Wynne, 2019, ACS applied materials & interfaces.

Health and Safety via Surface Modification of Polyurethanes

Wei Zhang, K. Wynne, A. Chakravorty, 2013 .

Elastase and the LasA Protease of Pseudomonas aeruginosa Are Secreted with Their Propeptides*

D. Ohman, E. Kessler, M. Safrin, 1998, The Journal of Biological Chemistry.

Staphylolysin is an effective therapeutic agent for Staphylococcus aureus experimental keratitis

D. Ohman, E. Kessler, M. Safrin, 2012, Graefe's Archive for Clinical and Experimental Ophthalmology.

Comparative Analysis of Plant and Animal Models for Characterization of Burkholderia cepacia Virulence

Steve P. Bernier, D. Ohman, D. Woods, 2003, Infection and Immunity.

Polyurethane biocidal polymeric surface modifiers.

K. Wynne, D. Ohman, Lynn F. Wood, 2006, Biomaterials.

Method for gene replacement in Pseudomonas aeruginosa used in construction of recA mutants: recA-independent instability of alginate production

J. Goldberg, D. Ohman, M. West, 1985, Journal of bacteriology.

Structural and Functional Characterization of Pseudomonas aeruginosa AlgX

P. Howell, H. Robinson, Perrin Baker, 2013, The Journal of Biological Chemistry.

Structural and Functional Characterization of Pseudomonas aeruginosa AlgX ROLE OF AlgX IN ALGINATE ACETYLATION *

P. Howell, H. Robinson, Perrin Baker, 2013 .

A Polycation Antimicrobial Peptide Mimic without Resistance Buildup against Propionibacterium Acnes.

K. Wynne, D. Ohman, M. Beckwith, 2017, Macromolecular bioscience.

Toxin A-deficient mutants of Pseudomonas aeruginosa PA103: isolation and characterization

J. Sadoff, B. Iglewski, D. Ohman, 1980, Infection and immunity.

Precise excision and instability of the transposon Tn5 in Pseudomonas aeruginosa.

J. Goldberg, D. Ohman, J. Won, 1990, Journal of general microbiology.

Identification of the Histidine Protein Kinase KinB inPseudomonas aeruginosa and Its Phosphorylation of the Alginate Regulator AlgB*

D. Wozniak, S. Ma, D. Ohman, 1997, The Journal of Biological Chemistry.

A More Sensitive Plate Assay for Detection of Protease Production by Pseudomonas aeruginosa

B. Iglewski, D. Ohman, P. Sokol, 1979, Journal of clinical microbiology.

Pseudomonas aeruginosa Elastase Provides an Escape from Phagocytosis by Degrading the Pulmonary Surfactant Protein-A

D. Ohman, Y. Hao, G. Lau, 2011, PloS one.

The elastase propeptide functions as an intramolecular chaperone required for elastase activity and secretion in Pseudomonas aeruginosa

D. Ohman, E. Kessler, J. Olson, 1995, Molecular microbiology.

Adaptations of Pseudomonas aeruginosa to the Cystic Fibrosis Lung Environment Can Include Deregulation of zwf, Encoding Glucose-6-Phosphate Dehydrogenase

S. Suh, D. Ohman, P. Phibbs, 2005, Journal of bacteriology.

Utilization of human respiratory secretions by mucoid Pseudomonas aeruginosa of cystic fibrosis origin

A. Chakrabarty, D. Ohman, 1982, Infection and immunity.

Autogenous regulation and kinetics of induction of Pseudomonas aeruginosa recA transcription as analyzed with operon fusions

D. Ohman, J. M. Horn, 1988, Journal of bacteriology.

Cloning and transcriptional regulation of the elastase lasA gene in mucoid and nonmucoid Pseudomonas aeruginosa

J. Goldberg, D. Ohman, 1987, Journal of bacteriology.

Isolation and characterization of toxin A excretion-deficient mutants of Pseudomonas aeruginosa PAO1

A. Hamood, S. E. West, B. Iglewski, 1992, Infection and immunity.

Molecular genetics of exopolysaccharide production by mucoidPseudomonas aeruginosa

D. Ohman, 1986, European Journal of Clinical Microbiology.

Extracellular proteolytic activation of Pseudomonas aeruginosa aminopeptidase (PaAP) and insight into the role of its non-catalytic N-terminal domain

R. Cahan, S. Suh, D. Ohman, 2021, PloS one.

Efficient production and processing of elastase and LasA by Pseudomonas aeruginosa require zinc and calcium ions

D. Ohman, J. Olson, Joan C. Olson, 1992, Journal of bacteriology.

Pseudomonas aeruginosa LasA Protease in Treatment of Experimental Staphylococcal Keratitis

D. Ohman, E. Kessler, M. Safrin, 2004, Antimicrobial Agents and Chemotherapy.

A continuous spectrophotometric assay for Pseudomonas aeruginosa LasA protease (staphylolysin) using a two-stage enzymatic reaction.

D. Ohman, E. Kessler, M. Safrin, 2004, Analytical biochemistry.

A Secreted Aminopeptidase of Pseudomonas aeruginosa

R. Cahan, D. Ohman, E. Kessler, 2001, The Journal of Biological Chemistry.

Pseudomonas aeruginosa LasA Protease as a Therapeutic Agent in Staphylococcal Keratitis

D. Ohman, E. Kessler, M. Safrin, 2004 .

Highly effective, water-soluble, hemocompatible 1,3-propylene oxide-based antimicrobials: poly[(3,3-quaternary/PEG)-copolyoxetanes].

Wei Zhang, K. Wynne, D. Ohman, 2011, Biomacromolecules.

Transcriptional analysis of the Pseudomonas aeruginosa genes algR, algB, and algD reveals a hierarchy of alginate gene expression which is modulated by algT

D. Wozniak, D. Ohman, Daniel J. Wozniak, 1994, Journal of bacteriology.

A simple alfalfa seedling infection model for Pseudomonas aeruginosa strains associated with cystic fibrosis shows AlgT (sigma-22) and RhlR contribute to pathogenesis

Sang-Jin Suh, S. Suh, D. Ohman, 2002, Proceedings of the National Academy of Sciences of the United States of America.

P. aeruginosa SGNH Hydrolase-Like Proteins AlgJ and AlgX Have Similar Topology but Separate and Distinct Roles in Alginate Acetylation

P. Howell, J. Whitney, H. Robinson, 2014, PLoS pathogens.

Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

S. Molin, A. Kharazmi, K. Mathee, 1999, Microbiology.

Secreted LasA of Pseudomonas aeruginosa is a staphylolytic protease.

D. Ohman, E. Kessler, M. Safrin, 1993, The Journal of biological chemistry.

Genetic mapping of chromosomal determinants for the production of the exopolysaccharide alginate in a Pseudomonas aeruginosa cystic fibrosis isolate

A. Chakrabarty, D. Ohman, A M Chakrabarty, 1981, Infection and immunity.

Genetic exchange of determinants for capsular polysaccharide biosynthesis between Klebsiella pneumoniae strains expressing serotypes K2 and K21a

D. Wozniak, A. Athamna, D. Ohman, 1993, Infection and immunity.

Cell wall‐inhibitory antibiotics activate the alginate biosynthesis operon in Pseudomonas aeruginosa: roles of σ22 (AlgT) and the AlgW and Prc proteases

A. J. Leech, D. Ohman, Lynn F. Wood, 2006, Molecular microbiology.

Isolation, characterization, and utilization of a temperature-sensitive allele of a Pseudomonas replicon.

S. Suh, D. Ohman, Brett Elmore, 2009, Journal of microbiological methods.

Epimerase Active Domain of Pseudomonas aeruginosa AlgG, a Protein That Contains a Right-Handed β-Helix

M. Dlakić, M. Franklin, D. Ohman, 2005, Journal of bacteriology.

Mucoid-to-nonmucoid conversion in alginate-producing Pseudomonas aeruginosa often results from spontaneous mutations in algT, encoding a putative alternate sigma factor, and shows evidence for autoregulation

D. Ohman, C. A. DeVries, C. A. Devries, 1994, Journal of bacteriology.

Involvement of the alginate algT gene and integration host factor in the regulation of the Pseudomonas aeruginosa algB gene

D. Wozniak, D. Ohman, 1993, Journal of bacteriology.

Effect of rpoS Mutation on the Stress Response and Expression of Virulence Factors in Pseudomonas aeruginosa

D. Hassett, S. E. West, D. Ohman, 1999, Journal of bacteriology.

Alginate Gene Regulation

D. Ohman, 2009 .

A mutation in algN permits trans activation of alginate production by algT in Pseudomonas species

J. Goldberg, D. Ohman, W. Gorman, 1993, Journal of bacteriology.

Use of a gene replacement cosmid vector for cloning alginate conversion genes from mucoid and nonmucoid Pseudomonas aeruginosa strains: algS controls expression of algT

D. Ohman, J. Flynn, JoANNE L. FLYNNt, 1988, Journal of bacteriology.

Activation of an elastase precursor by the lasA gene product of Pseudomonas aeruginosa

J. Goldberg, D. Ohman, 1987, Journal of bacteriology.

Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family

D. Ohman, J M Brint, D E Ohman, 1995, Journal of bacteriology.

Cloning of genes from mucoid Pseudomonas aeruginosa which control spontaneous conversion to the alginate production phenotype

D. Ohman, J. Flynn, 1988, Journal of bacteriology.

Use of cell wall stress to characterize σ22 (AlgT/U) activation by regulated proteolysis and its regulon in Pseudomonas aeruginosa

D. Ohman, Lynn F. Wood, 2009, Molecular microbiology.

Role of Alginate and Its O Acetylation in Formation of Pseudomonas aeruginosa Microcolonies and Biofilms

D. Nivens, M. Franklin, D. Ohman, 2001, Journal of bacteriology.

Proteome Analysis of the Effect of Mucoid Conversion on Global Protein Expression in Pseudomonas aeruginosa Strain PAO1 Shows Induction of the Disulfide Bond Isomerase, DsbA

K. Mathee, D. Ohman, S. Malhotra, 2000, Journal of bacteriology.

Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa*

P. Howell, P. Yip, J. Whitney, 2015, The Journal of Biological Chemistry.

Cell wall stress activates expression of a novel stress response facilitator (SrfA) under σ22 (AlgT/U) control in Pseudomonas aeruginosa.

D. Ohman, Lynn F. Wood, 2015, Microbiology.

Cloning and characterization of the Pseudomonas aeruginosa sodA and sodB genes encoding manganese- and iron-cofactored superoxide dismutase: demonstration of increased manganese superoxide dismutase activity in alginate-producing bacteria

D. Hassett, M. Vasil, D. Wozniak, 1993, Journal of bacteriology.

A substitution at His-120 in the LasA protease of Pseudomonas aeruginosa blocks enzymatic activity without affecting propeptide processing or extracellular secretion

D. Ohman, E. Kessler, J. Gustin, 1996, Journal of bacteriology.

Relationships among capsular structure, phagocytosis, and mouse virulence in Klebsiella pneumoniae

A. Athamna, D. Ohman, I. Ofek, 1995, Infection and immunity.

Isolation andCharacterization ofaPseudomonas aeruginosa PAOMutantThatProduces Altered Elastase

S. Cryz, B. Iglewski, D. Ohman, 1980 .

Mechanism of resistance to phagocytosis and pulmonary persistence in mucoid Pseudomonas aeruginosa

D. Ohman, D. Lebman, Warren Rowe, 2023, Frontiers in Cellular and Infection Microbiology.

Substitution of active-site His-223 in Pseudomonas aeruginosa elastase and expression of the mutated lasB alleles in Escherichia coli show evidence for autoproteolytic processing of proelastase

D. Ohman, E. Kessler, K. McIver, 1991, Journal of bacteriology.

High Antimicrobial Effectiveness with Low Hemolytic and Cytotoxic Activity for PEG/Quaternary Copolyoxetanes

Wei Zhang, K. Wynne, D. Ohman, 2014, Biomacromolecules.

Genetics of alginate biosynthesis in Pseudomonas aeruginosa

J. Goldberg, D. Ohman, 1990 .

Structural basis for alginate secretion across the bacterial outer membrane

Canhui Li, Christine E. Bear, Iain D. Hay, 2011, Proceedings of the National Academy of Sciences.

Electrosprayed Mesenchymal Stromal Cell Extracellular Matrix Nanoparticles Accelerate Cellular Wound Healing and Reduce Gram-Negative Bacterial Growth

D. Ohman, R. Heise, K. Rhoads, 2023, Pharmaceutics.

Biocidal activity of hydantoin-containing polyurethane polymeric surface modifiers

K. Wynne, K. Brunson, D. Ohman, 2007 .

Identification of residues in the Pseudomonas aeruginosa elastase propeptide required for chaperone and secretion activities.

D. Ohman, E. Kessler, K. McIver, 2004, Microbiology.

Phosphorylation-Independent Activity of the Response Regulators AlgB and AlgR in Promoting Alginate Biosynthesis in MucoidPseudomonas aeruginosa

D. Hassett, D. Wozniak, D. Ohman, 1998, Journal of bacteriology.

The NtrC Family Regulator AlgB, Which Controls Alginate Biosynthesis in Mucoid Pseudomonas aeruginosa, Binds Directly to the algD Promoter

D. Wozniak, D. Ohman, Lynn F. Wood, 2007, Journal of bacteriology.

Independent Regulation of MucD, an HtrA-Like Protease in Pseudomonas aeruginosa, and the Role of Its Proteolytic Motif in Alginate Gene Regulation

D. Ohman, Lynn F. Wood, 2006, Journal of bacteriology.

Expression, refolding, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa AlgE.

P. Howell, J. Whitney, A. Neculai, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Complete Genome Sequence of Pseudomonas aeruginosa Mucoid Strain FRD1, Isolated from a Cystic Fibrosis Patient

D. Wozniak, S. Suh, D. Ohman, 2015, Genome Announcements.

Evaluation of Pseudomonas aeruginosa staphylolysin (LasA protease) in the treatment of methicillin-resistant Staphylococcus aureus endophthalmitis in a rat model

D. Ohman, E. Kessler, M. Safrin, 2009, Graefe's Archive for Clinical and Experimental Ophthalmology.

Genetic linkage in Pseudomonas aeruginosa of algT and nadB: mutation in nadB does not affect NAD biosynthesis or alginate production.

D. Hassett, D. Ohman, C. A. DeVries, 1995, Gene.

A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production.

S. Molin, A. Kharazmi, C. Koh, 2012, Gene.

Expression, refolding, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa AlgE.

P. Howell, J. Whitney, A. Neculai, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Evidence for Two Promoters Internal to the Alginate Biosynthesis Operon in Pseudomonas aeruginosa

D. Ohman, J. Paletta, 2012, Current Microbiology.

Isolation and characterization of toxin A excretion-deficient mutants of Pseudomonas aeruginosa PAO1

A. Hamood, B. Iglewski, D. Ohman, 1992, Infection and immunity.

Experiments in Gene Manipulation

D. Ohman, Dennis E. Ohman, 1988 .