Dimitrios Morikis

发表

Structure-Based Integrative Computational and Experimental Approach for the Optimization of Drug Design

Christodoulos A. Floudas, Dimitrios Morikis, John D. Lambris, 2005, International Conference on Computational Science.

Predicting peptide structures using NMR data and deterministic global optimization

John L. Klepeis, Christodoulos A. Floudas, Dimitrios Morikis, 1999, J. Comput. Chem..

Faculty Opinions recommendation of Public domain databases for medicinal chemistry.

Dimitrios Morikis, 2012 .

Rational design of a complement inhibitor targeting C3 using NMR and combinatorial approaches

Dimitrios Morikis, John D. Lambris, Athena M. Soulika, 2002 .

Faculty Opinions recommendation of Cloud-based simulations on Google Exacycle reveal ligand modulation of GPCR activation pathways.

Dimitrios Morikis, 2014 .

Molecular Mechanism of Biased Ligand Conformational Changes in CC Chemokine Receptor 7

Dimitrios Morikis, Zied Gaieb, David D. Lo, 2016, J. Chem. Inf. Model..

The Two Sides of Complement C3d: Evolution of Electrostatics in a Link between Innate and Adaptive Immunity

Dimitrios Morikis, Chris A. Kieslich, C. Kieslich, 2012, PLoS Comput. Biol..

AESOP: A Python Library for Investigating Electrostatics in Protein Interactions.

Chris A Kieslich, Dimitrios Morikis, Reed E S Harrison, 2017, Biophysical journal.

Overcoming the Key Challenges in De Novo Protein Design: Enhancing Computational Efficiency and Incorporating True Backbone Flexibility

Li Zhang, Christodoulos A. Floudas, Martin S. Taylor, 2008 .

Conformational interconversion in compstatin probed with molecular dynamics simulations

Dimitrios Morikis, John D Lambris, Buddhadeb Mallik, 2003, Proteins.

Derivation of ligands for the complement C3a receptor from the C-terminus of C5a

Christodoulos A Floudas, Chris A Kieslich, Dimitrios Morikis, 2014, European journal of pharmacology.

Quantitative Modeling of the Alternative Pathway of the Complement System

Dimitrios Morikis, D. Morikis, Nehemiah Zewde, 2016, PloS one.

Design of peptide analogues with improved activity using a novel de novo protein design approach

John L. Klepeis, Christodoulos A. Floudas, Dimitrios Morikis, 2004 .

Exploring Protein-Protein and Protein-Ligand Interactions in the Immune System using Molecular Dynamics and Continuum Electrostatics

Phanourios Tamamis, Dimitrios Morikis, Chris A. Kieslich, 2012 .

Studies of Structure-Activity Relations of Complement Inhibitor Compstatin.

Dimitrios Morikis, John D. Lambris, Athena M. Soulika, 2004, The Journal of Immunology.

Physical methods for structure, dynamics and binding in immunological research.

Dimitrios Morikis, John D Lambris, J. Lambris, 2004, Trends in immunology.

Solution structure of Compstatin, a potent complement inhibitor

Dimitrios Morikis, John D Lambris, N. Assa‐Munt, 1998, Protein science : a publication of the Protein Society.

Studies of Structure-Activity Relations of Complement Inhibitor Compstatin 1

Dimitrios Morikis, John D Lambris, M. Roy, 2003 .

Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: The case of C3 inhibition by compstatin

Phanourios Tamamis, Dimitrios Morikis, Georgios Archontis, 2011, Proteins.

Electrostatic Modeling Predicts the Activities of Orthopoxvirus Complement Control Proteins1

Dimitrios Morikis, John D. Lambris, Madan Katragadda, 2005, The Journal of Immunology.

Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3.

Dimitrios Morikis, John D Lambris, J. Lambris, 2003, Molecular immunology.

Thermodynamic Studies on the Interaction of the Third Complement Component and Its Inhibitor, Compstatin*

Dimitrios Morikis, Madan Katragadda, John D Lambris, 2004, Journal of Biological Chemistry.

Design and NMR characterization of active analogues of compstatin containing non-natural amino acids.

Dimitrios Morikis, Madan Katragadda, John D Lambris, 2005, Journal of medicinal chemistry.

Binding Kinetics, Structure-Activity Relationship, and Biotransformation of the Complement Inhibitor Compstatin1

Dimitrios Morikis, John D. Lambris, W. T. Moore, 2000, The Journal of Immunology.

Species specificity of the complement inhibitor compstatin investigated by all‐atom molecular dynamics simulations

Christodoulos A Floudas, Phanourios Tamamis, Dimitrios Morikis, 2010, Proteins.

New Compstatin Peptides Containing N-Terminal Extensions and Non-Natural Amino Acids Exhibit Potent Complement Inhibition and Improved Solubility Characteristics

Christodoulos A. Floudas, George A. Khoury, Phanourios Tamamis, 2014, Journal of medicinal chemistry.

The Structural Basis of Compstatin Activity Examined by Structure-Function-based Design of Peptide Analogs and NMR* 210

Dimitrios Morikis, John D. Lambris, Patricia A. Jennings, 2002, The Journal of Biological Chemistry.

Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures.

Christodoulos A Floudas, Phanourios Tamamis, Chris A Kieslich, 2013, Experimental eye research.

Insights into the Structure, Correlated Motions, and Electrostatic Properties of Two HIV-1 gp120 V3 Loops

Phanourios Tamamis, Dimitrios Morikis, Chris A. Kieslich, 2012, PloS one.

Discovery of Small Molecules for Fluorescent Detection of Complement Activation Product C3d.

Jung-Hsin Lin, Vicente Nuñez, Dimitrios Morikis, 2015, Journal of medicinal chemistry.

Molecular Dynamics in Drug Design: New Generations of Compstatin Analogs

Christodoulos A Floudas, Phanourios Tamamis, Dimitrios Morikis, 2012, Chemical biology & drug design.

Electrostatic Clustering and Free Energy Calculations Provide a Foundation for Protein Design and Optimization

Dimitrios Morikis, Chris A. Kieslich, C. Kieslich, 2010, Annals of Biomedical Engineering.

Alteration of heme axial ligands by site-directed mutagenesis: a cytochrome becomes a catalytic demethylase

Dimitrios Morikis, J. Timothy Sage, Stephen G. Sligar, 1987 .

Integrated computational and experimental approach for lead optimization and design of compstatin variants with improved activity.

Christodoulos A Floudas, Dimitrios Morikis, John D Lambris, 2003, Journal of the American Chemical Society.

Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties

Chris A Kieslich, Dimitrios Morikis, C. Kieslich, 2012, BMC biophysics.