S. Toennes

M. Uder, R. Schmieder, C. Ott, 2015, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

Pharmacoepigenetics of the role of DNA methylation in μ-opioid receptor expression in different human brain regions.

A. Ultsch, Claudia Knothe, J. Lötsch, 2016, Epigenomics.

Estimating the age of the adult stages of the blow flies Lucilia sericata and Calliphora vicina (Diptera: Calliphoridae) by means of the cuticular hydrocarbon n-pentacosane.

S. Toennes, J. Amendt, M. Verhoff, 2017, Science & justice : journal of the Forensic Science Society.

Investigation of a recently detected THCCOOH isomer: Post mortem findings and comparison with Δ(8)-THCCOOH.

S. Toennes, A. Paulke, S. Hanisch, 2015, Forensic science international.

Variability of residual platelet function despite clopidogrel treatment in patients with peripheral arterial occlusive disease.

S. Toennes, H. Mani, E. Lindhoff‐Last, 2010, Atherosclerosis.

Analysis of drugs of abuse in Cerumen - correlation of postmortem analysis results with those for blood, urine and hair.

M. Schubert-Zsilavecz, S. Toennes, Sarah C. Koelzer, 2017, Drug testing and analysis.

Impact of drug adherence on blood pressure response to alcohol-mediated renal denervation

F. Maes, H. Parise, F. Mahfoud, 2022, Blood pressure.

Neurocognition and Subjective Experience Following Acute Doses of the Synthetic Cannabinoid JWH-018: Responders Versus Nonresponders

J. Ramaekers, E. Theunissen, K. Kuypers, 2019, Cannabis and cannabinoid research.

Factors leading to the degradation/loss of insulin in postmortem blood samples.

S. Toennes, G. Kauert, C. Wunder, 2014, Forensic science international.

Selective sequestration of cardenolide isomers by two species of Danaus butterflies (Lepidoptera: Nymphalidae: Danainae)

D. Mebs, S. Toennes, C. Wunder, 2012, Chemoecology.

Ritualistic use of ayahuasca enhances a shared functional connectome identity with others

E. Amico, J. Ramaekers, S. Toennes, 2022, bioRxiv.

Coping with noxious effects of quinine by praying mantids (Mantodea) and spiders (Araneae)

D. Mebs, S. Toennes, C. Wunder, 2019, Toxicon : official journal of the International Society on Toxinology.

Lack of effects of a "sobering" product, "Eezup!", on the blood ethanol and congener alcohol concentration.

S. Toennes, A. Paulke, C. Wunder, 2017, Forensic science international.

Gas chromatographic-mass spectrometric detection of anhydroecgonine methyl ester (methylecgonidine) in human serum as evidence of recent smoking of crack.

S. Toennes, G. Kauert, A. Fandiño, 1999, Journal of Chromatography B: Biomedical Sciences and Applications.

Nephropathy in illicit drug abusers: a postmortem analysis.

H. Bratzke, M. Bickel, K. Amann, 2014, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Chronic alcohol abuse may lead to high skin iron content, but not to hepatic siderosis.

M. Wurglics, G. Skopp, S. Toennes, 2019, Forensic science international.

11‐nor‐9‐carboxy‐&Dgr;9‐tetrahydrocannabinol glucuronide exhibits acyl‐migration isomers

S. Toennes, A. Paulke, S. Hanisch, 2017, Journal of pharmaceutical and biomedical analysis.

The role of P-glycoprotein in CNS antihistamine effects

M. Mehta, J. Ramaekers, E. Theunissen, 2013, Psychopharmacology.

Sleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour

S. Toennes, A. Paulke, C. Wunder, 2014, International Journal of Legal Medicine.

Comparison of cannabinoid pharmacokinetic properties in occasional and heavy users smoking a marijuana or placebo joint.

J. Ramaekers, E. Theunissen, S. Toennes, 2008, Journal of analytical toxicology.

Drug adherence and psychological factors in patients with apparently treatment‐resistant hypertension: Yes but which ones?

G. Petit, P. de Timary, P. Wallemacq, 2022, Journal of clinical hypertension.

Psychological determinants of drug adherence and severity of hypertension in patients with apparently treatment-resistant vs. controlled hypertension

G. Petit, P. de Timary, P. Wallemacq, 2022, Blood pressure.

Amphibian myiasis. Blowfly larvae (Lucilia bufonivora, Diptera: Calliphoridae) coping with the poisonous skin secretion of the common toad (Bufo bufo)

Georg Petschenka, D. Mebs, S. Toennes, 2014, Chemoecology.

Chiral Serum Pharmacokinetics of 4-Fluoroamphetamine after Controlled Oral Administration: Can (R)/(S) Concentration Ratios Help in Interpreting Forensic Cases?

J. Ramaekers, C. Hess, S. Toennes, 2020, Journal of analytical toxicology.

Excretion of 4-fluoroamphetamine and three metabolites in urine after controlled oral ingestion.

J. Ramaekers, E. Theunissen, S. Toennes, 2019, Journal of pharmaceutical and biomedical analysis.

Pharmacokinetic properties of 4-fluoroamphetamine in serum and oral fluid after oral ingestion.

J. Ramaekers, E. Theunissen, K. Kuypers, 2019, Drug testing and analysis.

Pharmacokinetic properties of the synthetic cannabinoid JWH‐018 and of its metabolites in serum after inhalation

J. Ramaekers, E. Theunissen, S. Toennes, 2017, Journal of pharmaceutical and biomedical analysis.

Retrospective analysis of synthetic cannabinoids in serum samples--epidemiology and consumption patterns.

S. Toennes, A. Paulke, C. Wunder, 2014, Forensic science international.

Pitfall in cannabinoid analysis—detection of a previously unrecognized interfering compound in human serum

S. Toennes, A. Paulke, C. Wunder, 2014, Analytical and Bioanalytical Chemistry.

Criminal poisoning of commuters in Bangladesh: prospective and retrospective study.

U. Kuch, S. Toennes, A. Basher, 2008, Forensic science international.

Resistant hypertension? Assessment of adherence by toxicological urine analysis

S. Toennes, A. Paulke, C. Wunder, 2013, Journal of hypertension.

Pharmacological data science perspective on fatal incidents of morphine treatment.

J. Lötsch, S. Toennes, R. Dudziak, 2022, Pharmacology & therapeutics.

Subjective aggression during alcohol and cannabis intoxication before and after aggression exposure

J. Ramaekers, E. Theunissen, K. Kuypers, 2016, Psychopharmacology.

Driving under the influence of khat--alkaloid concentrations and observations in forensic cases.

S. Toennes, G. Kauert, 2004, Forensic science international.

Evading plant defence: Infestation of poisonous milkweed fruits (Asclepiadaceae) by the fruit fly Dacus siliqualactis (Diptera: Tephritidae)

D. Mebs, S. Toennes, C. Wunder, 2017, Toxicon : official journal of the International Society on Toxinology.

Tetrodotoxin in Asian newts (Salamandridae)

D. Mebs, M. Yotsu-Yamashita, S. Toennes, 2017, Toxicon : official journal of the International Society on Toxinology.

Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters

E. Seifried, J. Oldenburg, N. von Ahsen, 2010, European Journal of Clinical Pharmacology.

Identification of anhydroecgonine methyl ester N-oxide, a new metabolite of anhydroecgonine methyl ester, using electrospray mass spectrometry.

M. Karas, S. Toennes, G. Kauert, 2002, Journal of mass spectrometry : JMS.

Argyreia nervosa (Burm. f.): receptor profiling of lysergic acid amide and other potential psychedelic LSD-like compounds by computational and binding assay approaches.

H. Stark, E. Proschak, Bardya Djahanschiri, 2013, Journal of ethnopharmacology.

Toxicological Screening of Drug Facilitated Crime among Travelers in Dhaka, Bangladesh

U. Kuch, S. Toennes, A. Basher, 2017 .

A First-in-Man Study with 4-Fluoroamphetamine Demonstrates it Produces a Mild Psychedelic State

J. Ramaekers, E. Theunissen, K. Kuypers, 2019, Journal of psychoactive drugs.

Studies on the alkaloid composition of the Hawaiian Baby Woodrose Argyreia nervosa, a common legal high.

M. Schubert-Zsilavecz, M. Wurglics, S. Toennes, 2015, Forensic science international.

PTCA (1H-pyrrole-2,3,5-tricarboxylic acid) as a marker for oxidative hair treatment.

M. Schubert-Zsilavecz, S. Toennes, Sylvia I Meier, 2018, Drug testing and analysis.

Identification of legal highs--ergot alkaloid patterns in two Argyreia nervosa products.

M. Schubert-Zsilavecz, M. Wurglics, S. Toennes, 2014, Forensic science international.

Analysis of lysergic acid amide in human serum and urine after ingestion of Argyreia nervosa seeds

S. Toennes, A. Paulke, C. Wunder, 2012, Analytical and Bioanalytical Chemistry.

Variable adverse effects in subjects after ingestion of equal doses of Argyreia nervosa seeds.

S. Toennes, A. Paulke, C. Wunder, 2012, Forensic science international.

Pharmacokinetics of cathinone, cathine and norephedrine after the chewing of khat leaves.

S. Toennes, G. Kauert, S. Harder, 2003, British journal of clinical pharmacology.

Excretion and detection of cathinone, cathine, and phenylpropanolamine in urine after kath chewing.

S. Toennes, G. Kauert, 2002, Clinical chemistry.

Detection of lawsone (2-hydroxy-1,4-naphthoquinone) in henna treated hair.

M. Schubert-Zsilavecz, S. Toennes, Sylvia I Meier, 2019, Forensic science international.

Influence of bleaching and coloring on ethyl glucuronide content in human hair.

M. Schubert-Zsilavecz, S. Toennes, A. Paulke, 2018, Drug testing and analysis.

Assessment of adherence to diuretics and β-blockers by serum drug monitoring in comparison to urine analysis

P. Wallemacq, S. Toennes, C. Wunder, 2020, Blood pressure.

Evaluation of the dose-related concentration approach in therapeutic drug monitoring of diuretics and β-blockers – drug classes with low adherence in antihypertensive therapy

N. Obermüller, S. Toennes, C. Wunder, 2019, Scientific Reports.

Pharmacokinetic properties of the synthetic cannabinoid JWH-018 in oral fluid after inhalation.

J. Ramaekers, E. Theunissen, S. Toennes, 2018, Drug testing and analysis.

Driving under the influence of drugs -- evaluation of analytical data of drugs in oral fluid, serum and urine, and correlation with impairment symptoms.

S. Toennes, M. Moeller, G. Kauert, 2005, Forensic science international.

Unknown Herbal Poisoning with Fatal Outcome

U. Kuch, S. Toennes, A. Basher, 2018 .

C. Hess, S. Toennes, D. Remane, 2020, Forensic science international.

Importance of vacutainer selection in forensic toxicological analysis of drugs of abuse.

S. Toennes, G. Kauert, S W Toennes, 2001, Journal of analytical toxicology.

Studies on in vitro degradation of anhydroecgonine methyl ester (methylecgonidine) in human plasma.

S. Toennes, G. Kauert, A. Fandiño, 2002, Journal of analytical toxicology.

Determination of naltrexone and 6-beta-naltrexol in human plasma following implantation of naltrexone pellets using gas chromatography-mass spectrometry.

S. Grüsser, S. Toennes, G. Kauert, 2004, Journal of pharmaceutical and biomedical analysis.

A Phase 1, Dose-Ranging Study to Assess Safety and Psychoactive Effects of a Vaporized 5-Methoxy-N, N-Dimethyltryptamine Formulation (GH001) in Healthy Volunteers

C. V. Van Leeuwen, J. Ramaekers, S. Toennes, 2021, Frontiers in Pharmacology.

Metabolomics and integrated network analysis reveal roles of endocannabinoids and large neutral amino acid balance in the ayahuasca experience.

Ó. Pozo, J. Ramaekers, R. de la Torre, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users

J. Ramaekers, E. Theunissen, S. Toennes, 2011, Analytical and bioanalytical chemistry.

[Suicide in children and adolescents - a 13-year study with 78 cases].

C. Freitag, M. Kettner, S. Toennes, 2012, Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie.

Incidence of axonal injury in human brain tissue

H. Bratzke, S. Toennes, C. Niess, 2002, Acta Neuropathologica.

Factitious anticoagulant-resistance as a cause of recurrent arterial bypass graft occlusions

C. Geisen, S. Toennes, H. Mani, 2007, Thrombosis and Haemostasis.

Tolerance and cross-tolerance to neurocognitive effects of THC and alcohol in heavy cannabis users

J. Ramaekers, E. Theunissen, S. Toennes, 2010, Psychopharmacology.

Influence of ethanol on the pharmacokinetic properties of Δ9-tetrahydrocannabinol in oral fluid.

J. Ramaekers, E. Theunissen, S. Toennes, 2013, Journal of analytical toxicology.

Influence of ethanol on the pharmacokinetics of methylphenidate's metabolites ritalinic acid and ethylphenidate.

S. Toennes, G. Kauert, M. Koehm, 2011, Arzneimittel-Forschung.

Pharmacokinetic properties of delta9-tetrahydrocannabinol in serum and oral fluid.

J. Ramaekers, S. Toennes, E. Schneider, 2007, Journal of analytical toxicology.

Use of lidocaine in endotracheal intubation. Blood and urine concentrations in patients and deceased after unsuccessful resuscitation.

K. Zacharowski, S. Toennes, J. Meier, 2014, Forensic Science International.

Efficient cleavage of conjugates of drugs or poisons by immobilized beta-glucuronidase and arylsulfatase in columns.

S. Toennes, H. Maurer, 1999, Clinical chemistry.

Loss of skin alkaloids in poison toads, Melanophryniscus klappenbachi (Anura: Bufonidae) when fed alkaloid-free diet.

D. Mebs, S. Toennes, W. Pogoda, 2018, Toxicon : official journal of the International Society on Toxinology.

Intoxication by a synthetic cannabinoid (JWH-018) causes cognitive and psychomotor impairment in recreational cannabis users

J. Ramaekers, E. Theunissen, K. Kuypers, 2021, Pharmacology Biochemistry and Behavior.

Alterations of the Ceramide Metabolism in the Peri-Infarct Cortex Are Independent of the Sphingomyelinase Pathway and Not Influenced by the Acid Sphingomyelinase Inhibitor Fluoxetine

N. Ferreirós, J. Pfeilschifter, S. Schwalm, 2015, Neural plasticity.

A fatal human intoxication with the herbicide allyl alcohol (2-propen-1-ol).

S. Toennes, G. Kauert, K. Schmidt, 2002, Journal of analytical toxicology.

Low Doses of Ethanol Enhance LTD-like Plasticity in Human Motor Cortex

U. Ziemann, S. Toennes, C. Lücke, 2015, Neuropsychopharmacology.

Altered gene expression in the prefrontal cortex of young rats induced by the ADHD drug atomoxetine

C. Freitag, S. Toennes, E. Niederberger, 2013, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Psychotomimetic symptoms after a moderate dose of a synthetic cannabinoid (JWH-018): implications for psychosis

J. Ramaekers, E. Theunissen, K. Kuypers, 2021, Psychopharmacology.

Excretion of metabolites of the synthetic cannabinoid JWH-018 in urine after controlled inhalation.

J. Ramaekers, E. Theunissen, S. Toennes, 2018, Journal of pharmaceutical and biomedical analysis.

Determination of Clopidogrel Main Metabolite in Plasma: A Useful Tool for Monitoring Therapy?

S. Toennes, G. Kauert, H. Mani, 2008, Therapeutic drug monitoring.

Impact of pharmacokinetic (CYP2C9) and pharmacodynamic (VKORC1, F7, GGCX, CALU, EPHX1) gene variants on the initiation and maintenance phases of phenprocoumon therapy

E. Seifried, J. Oldenburg, C. Geisen, 2010, Thrombosis and Haemostasis.

Predictors of blood pressure control in patients with resistant hypertension after intensive management in two expert centres: the Brussels-Torino experience

G. Petit, P. de Timary, P. Wallemacq, 2019, Blood pressure.

Assessment of the acute effects of 2C-B vs psilocybin on subjective experience, mood and cognition

J. Ramaekers, E. Theunissen, K. Kuypers, 2023, bioRxiv.

Drug liking and wanting, not impulsive action or reflection is increased by 4-fluoroamphetamine

J. Ramaekers, E. Theunissen, K. Kuypers, 2018, Psychopharmacology.

Artifact production in the assay of anhydroecgonine methyl ester in serum using gas chromatography-mass spectrometry.

S. Toennes, G. Kauert, A. Fandiño, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Application of LC–TOF MS to analysis of hemoglobin acetaldehyde adducts in alcohol detoxification patients

S. Toennes, G. Kauert, Moritz G. Wagner, 2010, Analytical and bioanalytical chemistry.

Acetaldehyde adducts of human hemoglobin : Identification of modified hemoglobin N-terminal peptides in blood samples by LC / TOF-MS

S. Toennes, G. Kauert, Moritz G. Wagner, 2008 .

[Severe encephalopathy after taking a "phytopharmacon" from Vietnam].

D. Mebs, S. Toennes, P. Schwimmbeck, 2013, Deutsche Medizinische Wochenschrift.

Brain reactivity to alcohol and cannabis marketing during sobriety and intoxication

E. Evers, J. Ramaekers, E. Theunissen, 2017, Addiction biology.

Genotype-phenotype feasibility studies on khat abuse, traumatic experiences and psychosis in Ethiopia.

Till F. M. Andlauer, M. Rietschel, T. Schulze, 2020, Psychiatric genetics.

Cannabis increases susceptibility to false memory

E. Loftus, A. Blokland, J. Ramaekers, 2020, Proceedings of the National Academy of Sciences.

Remembering Molly: Immediate and delayed false memory formation after acute MDMA exposure

A. Blokland, J. Ramaekers, H. Otgaar, 2022, European Neuropsychopharmacology.

Neurocognition and subjective experience following acute doses of the synthetic cannabinoid JWH‐018: a phase 1, placebo‐controlled, pilot study

J. Ramaekers, E. Theunissen, K. Kuypers, 2018, British journal of pharmacology.

Persisting Effects of Ayahuasca on Empathy, Creative Thinking, Decentering, Personality, and Well-Being

J. Ramaekers, K. Kuypers, S. Toennes, 2021, Frontiers in Pharmacology.

Pharmacokinetic properties of delta9-tetrahydrocannabinol in oral fluid of occasional and chronic users.

J. Ramaekers, E. Theunissen, S. Toennes, 2010, Journal of analytical toxicology.

Neurophysiological functioning of occasional and heavy cannabis users during THC intoxication

J. Ramaekers, E. Theunissen, A. Sambeth, 2011, Psychopharmacology.

Assay of Delta9-tetrahydrocannabinol (THC) in oral fluid-evaluation of the OraSure oral specimen collection device.

S. Toennes, G. Kauert, S. Iwersen-Bergmann, 2006, Journal of analytical toxicology.

Driving under the influence of cocaine: Quantitative determination of basic drugs in oral fluid obtained during roadside controls and a controlled study with cocaine users.

J. Ramaekers, N. Samyn, S. Toennes, 2018, Drug testing and analysis.

Evaluation of Δ(9) -tetrahydrocannabinol detection using DrugWipe5S(®) screening and oral fluid quantification after Quantisal™ collection for roadside drug detection via a controlled study with chronic cannabis users.

J. Ramaekers, N. Samyn, S. Toennes, 2015, Drug testing and analysis.

Investigation of a recently detected 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol isomer: Studies on the degradation of 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol glucuronide.

S. Toennes, A. Paulke, S. Hanisch, 2016, Journal of pharmaceutical and biomedical analysis.

Reduced responsiveness of the reward system is associated with tolerance to cannabis impairment in chronic users

J. Jansen, J. Ramaekers, E. Theunissen, 2019, Addiction biology.

Caffeine Enhances Endothelial Repair by an AMPK-Dependent Mechanism

A. Zernecke, C. Weber, S. Fichtlscherer, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Khat use and occurrence of psychotic symptoms in the general male population in Southwestern Ethiopia: evidence for sensitization by traumatic experiences

M. Rietschel, T. Schulze, E. Susser, 2017, World Psychiatry.

Poor alkaloid sequestration by arrow poison frogs of the genus Phyllobates from Costa Rica.

G. Köhler, D. Mebs, S. Toennes, 2014, Toxicon : official journal of the International Society on Toxinology.

Deleterious Effects of a Low Amount of Ethanol on LTP-Like Plasticity in Human Cortex

U. Ziemann, S. Toennes, Lucia Kriváneková, 2014, Neuropsychopharmacology.

Detection of oxidative hair treatment using fluorescence microscopy.

M. Schubert-Zsilavecz, S. Toennes, A. Paulke, 2016, Drug testing and analysis.

Missed chances? Sequestration and non-sequestration of alkaloids by moths (Lepidoptera).

D. Mebs, S. Toennes, C. Wunder, 2023, Toxicon : official journal of the International Society on Toxinology.

Selective sequestration of cardenolide isomers by two species of Danaus butterflies (Lepidoptera: Nymphalidae: Danainae)

D. Mebs, S. Toennes, C. Wunder, 2012, Chemoecology.

Altered State of Consciousness and Mental Imagery as a Function of N, N-dimethyltryptamine Concentration in Ritualistic Ayahuasca Users

J. Ramaekers, S. Toennes, N. Mason, 2023, Journal of Cognitive Neuroscience.

Feeding on toxic prey. The praying mantis (Mantodea) as predator of poisonous butterfly and moth (Lepidoptera) caterpillars

D. Mebs, S. Toennes, C. Wunder, 2017, Toxicon.

Lack of alkaloids and tetrodotoxin in the neotropical frogs Allobates spp. (Aromobatidae) and Silverstoneia flotator (Dendrobatidae).

G. Köhler, D. Mebs, M. Yotsu-Yamashita, 2018, Toxicon : official journal of the International Society on Toxinology.

Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users

J. Ramaekers, E. Theunissen, S. Toennes, 2009, Journal of psychopharmacology.

Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution

N. Broers, M. V. van Boxtel, J. Ramaekers, 2018, Psychopharmacology.

Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin

J. Jansen, J. Ramaekers, A. Feilding, 2020, Neuropsychopharmacology.

Analysis of 4-fluoroamphetamine in cerumen after controlled oral application.

J. Ramaekers, M. Schubert-Zsilavecz, E. Theunissen, 2020, Drug testing and analysis.

Subjective aggression during alcohol and cannabis intoxication before and after aggression exposure

J. Ramaekers, E. Theunissen, K. Kuypers, 2016, Psychopharmacology.

Studies on hydrolytic and oxidative metabolic pathways of anhydroecgonine methyl ester (methylecgonidine) using microsomal preparations from rat organs.

S. Toennes, G. Kauert, A. Fandiño, 2002, Chemical research in toxicology.

[Suicide in children and adolescents - a 13-year study with 78 cases].

C. Freitag, M. Kettner, S. Toennes, 2012, Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie.

A single dose of cocaine enhances prospective memory performance

J. Ramaekers, R. Verkes, E. Theunissen, 2018, Journal of psychopharmacology.

Erratum: Cannabis and tolerance: acute drug impairment as a function of cannabis use history

R. Verkes, E. Theunissen, K. Kuypers, 2016, Scientific Reports.

Cannabis and tolerance: acute drug impairment as a function of cannabis use history

J. Ramaekers, R. Verkes, E. Theunissen, 2016, Scientific Reports.

Adherence to antihypertensive drug treatment in kidney transplant recipients

P. Wallemacq, S. Toennes, A. Persu, 2021, Blood pressure.

Studies on metabolic pathways of cocaine and its metabolites using microsome preparations from rat organs.

S. Toennes, G. Kauert, M. Walther, 2003, Chemical research in toxicology.