M. Larsen

发表

Functional Annotation of the Putative Orphan Caenorhabditis elegans G-protein-coupled Receptor C10C6.2 as a FLP15 Peptide Receptor*

T. Kubiak, M. Larsen, M. R. Zantello, 2003, Journal of Biological Chemistry.

Differential Activation of “Social” and “Solitary” Variants of the Caenorhabditis elegans G Protein-coupled Receptor NPR-1 by Its Cognate Ligand AF9*

T. Kubiak, M. Larsen, M. R. Zantello, 2003, Journal of Biological Chemistry.

Microscale Adaptation of In Vitro Transcription/Translation for High‐Throughput Screening of Natural Product Extract Libraries

D. Sherman, M. Larsen, A. N. Lowell, 2015, Chemical biology & drug design.

Unbiased screen identifies aripiprazole as a modulator of abundance of the polyglutamine disease protein, ataxin-3.

M. Ivanova, H. Paulson, J. Gestwicki, 2016, Brain : a journal of neurology.

FMRFamide‐like peptides encoded on the flp‐18 precursor gene activate two isoforms of the orphan Caenorhabditis elegans G‐protein‐coupled receptor Y58G8A.4 heterologously expressed in mammalian cells

Martha J Larsen, T. Geary, T. Kubiak, 2008, Biopolymers.

Type A allatostatins from Drosophila melanogaster and Diplotera puncata activate two Drosophila allatostatin receptors, DAR-1 and DAR-2, expressed in CHO cells.

T. Kubiak, M. Larsen, M. R. Zantello, 2001, Biochemical and biophysical research communications.

Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase.

Stacie L. Bulfer, R. Trievel, M. Larsen, 2011, Analytical biochemistry.

Strategy for Tumor-Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer

Benjamin L. Kidder, J. Saxton, P. Shaw, 2018, Clinical Cancer Research.

Complementary Cell-Based High-Throughput Screens Identify Novel Modulators of the Unfolded Protein Response

R. Neubig, R. Kaufman, D. Sherman, 2011, Journal of biomolecular screening.

Narrow-Spectrum Inhibitors of Campylobacter jejuni Flagellar Expression and Growth

V. DiRita, M. Larsen, Jeremiah G. Johnson, 2015, Antimicrobial Agents and Chemotherapy.

Small molecule screening identifies regulators of the transcription factor ΔFosB.

E. Nestler, Yun Wang, G. Rudenko, 2012, ACS chemical neuroscience.

The role of HTS in drug discovery at the University of Michigan.

D. Sherman, A. Mapp, J. Grembecka, 2014, Combinatorial chemistry & high throughput screening.

Identification of a platyhelminth neuropeptide receptor.

T. Geary, T. Day, A. Maule, 2007, International journal for parasitology.

Discovery of Allosteric and Selective Inhibitors of Inorganic Pyrophosphatase from Mycobacterium tuberculosis.

S. Garneau‐Tsodikova, O. Tsodikov, M. Larsen, 2016, ACS chemical biology.

High-Throughput Screening of the Virulence Regulator VirF

M. Larsen, G. Garcia, Julie K. Hurt, 2010, Journal of biomolecular screening.

Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts.

Renju T. Jacob, R. Kaufman, D. Sherman, 2015, ACS medicinal chemistry letters.

Identification of thieno[3,2-b]pyrrole derivatives as novel small molecule inhibitors of neurotropic alphaviruses.

David J. Miller, R. Neubig, M. Larsen, 2009, The Journal of infectious diseases.

The Combined Use of Alphavirus Replicons and Pseudoinfectious Particles for the Discovery of Antivirals Derived from Natural Products

David J. Miller, D. Sherman, G. Tamayo-Castillo, 2015, Journal of biomolecular screening.

MScreen: an integrated compound management and high-throughput screening data storage and analysis system.

David H Sherman, Renju T. Jacob, Renju T Jacob, 2012, Journal of biomolecular screening.

From proteomics to discovery of first-in-class ST2 inhibitors active in vivo.

Greg L. Hura, J. Stuckey, Krishnapriya Chinnaswamy, 2018, JCI insight.

An inhibitor of the protein kinases TBK1/IKKε improves obesity-related metabolic dysfunctions

I. Hochberg, R. Evans, M. Downes, 2013, Nature Medicine.

High-Throughput Screening for Small-Molecule Inhibitors of LARG-Stimulated RhoA Nucleotide Binding via a Novel Fluorescence Polarization Assay

R. Neubig, J. Sondek, M. Larsen, 2009, Journal of biomolecular screening.

Effects of KHEYLRFamide and KNEFIRFamide on cyclic adenosine monophosphate levels in Ascaris suum somatic muscle.

T. Geary, N. Marks, M. Larsen, 2003, International journal for parasitology.

Development and Implementation of an HTS-Compatible Assay for the Discovery of Selective Small-Molecule Ligands for Pre-microRNAs

Daniel A. Lorenz, M. Larsen, A. Garner, 2018, SLAS discovery : advancing life sciences R & D.

Inhibitors of TonB Function Identified by a High-Throughput Screen for Inhibitors of Iron Acquisition in Uropathogenic Escherichia coli CFT073

H. Mobley, M. Larsen, P. Kirchhoff, 2014, mBio.

Genome-Wide Small Interfering RNA Screening Reveals a Role for Cullin3–Really Interesting New Gene Ligase Signaling in Heterologous Sensitization of Adenylyl Cyclase

V. Watts, M. Larsen, N. Santoro, 2019, The Journal of Pharmacology and Experimental Therapeutics.

High-Throughput Screen for Escherichia coli Heat Shock Protein 70 (Hsp70/DnaK)

J. Gestwicki, C. P. Walczak, M. Larsen, 2010, Journal of biomolecular screening.

Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice

J. Musser, I. Sitkiewicz, M. Larsen, 2012, Proceedings of the National Academy of Sciences.

Pharmacology of FMRFamide‐related Peptides in Helminths

D. P. Thompson, T. Geary, T. Day, 1999, Annals of the New York Academy of Sciences.

Reversible, Allosteric Small-Molecule Inhibitors of Regulator of G Protein Signaling Proteins

R. Neubig, Levi L. Blazer, S. Husbands, 2010, Molecular Pharmacology.

Inhibition of Furin/Proprotein Convertase-catalyzed Surface and Intracellular Processing by Small Molecules*

Alnawaz Rehemtulla, Robert Day, Brian D Ross, 2009, The Journal of Biological Chemistry.

AF2 interaction with Ascaris suum body wall muscle membranes involves G-protein activation.

T. Kubiak, M. Larsen, M. R. Zantello, 2003, Biochemical and biophysical research communications.

Cloning and functional expression of the first Drosophila melanogaster sulfakinin receptor DSK-R1.

C. Bannow, T. Kubiak, M. Larsen, 2002, Biochemical and biophysical research communications.

Functional expression and characterization of the C. elegans G-protein-coupled FLP-2 Receptor (T19F4.1) in mammalian cells and yeast.

T. Geary, T. Kubiak, M. Larsen, 2013, International journal for parasitology. Drugs and drug resistance.

Narrow-Spectrum Inhibitors of Campylobacter jejuni Flagellar Expression and Growth

V. DiRita, M. Larsen, Jeremiah G. Johnson, 2015, Antimicrobial Agents and Chemotherapy.

MScreen

Renju T. Jacob, R. Neubig, D. Sherman, 2012, Journal of biomolecular screening.