Chin-Ho Chen

发表

Inhibitory Effect of b-AP15 on the 20S Proteasome

Li Huang, Katherine Jung, Chin-Ho Chen, 2014, Biomolecules.

Synthesis of Lithocholic Acid Derivatives as Proteasome Regulators.

Li Huang, Katherine Jung, Chin-Ho Chen, 2012, ACS medicinal chemistry letters.

Activation and inhibition of the proteasome by betulinic acid and its derivatives

Li Huang, Chin-Ho Chen, P. Ho, 2007, FEBS letters.

Design, synthesis, and evaluation of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase.

E. De Clercq, Dongwei Kang, C. Pannecouque, 2020, European journal of medicinal chemistry.

Drug-like property-driven optimization of 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against rilpivirine-resistant mutant virus

Li Huang, Chin-Ho Chen, K. Lee, 2017, Bioorganic & medicinal chemistry letters.

Identification of highly potent and selective Cdc25 protein phosphatases inhibitors from miniaturization click-chemistry-based combinatorial libraries.

Dongwei Kang, P. Zhan, Xinyong Liu, 2019, European journal of medicinal chemistry.

In-Depth Analysis of the Interaction of HIV-1 with Cellular microRNA Biogenesis and Effector Mechanisms

B. Cullen, O. Flores, M. Stevenson, 2013, mBio.

Betulinic acid derivatives as HIV-1 antivirals.

C. Aiken, Chin-Ho Chen, 2005, Trends in molecular medicine.

Synthesis of betulinic acid derivatives as entry inhibitors against HIV-1 and bevirimat-resistant HIV-1 variants.

Li Huang, Chin-Ho Chen, Z. Dang, 2012, Bioorganic & medicinal chemistry letters.

The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3',3'-dimethylsuccinyl}-betulinic acid

C. Aiken, Chin-Ho Chen, Jing-jiao Zhou, 2004, Retrovirology.

Discovery of novel 5-fluoro-N2,N4-diphenylpyrimidine-2,4-diamines as potent inhibitors against CDK2 and CDK9.

Li Huang, Chin-Ho Chen, K. Lee, 2015, MedChemComm.

Induction of a nonproductive conformational change in gp120 by a small molecule HIV type 1 entry inhibitor.

Li Huang, Chin-Ho Chen, P. Ho, 2007, AIDS research and human retroviruses.

Neutralization epitopes of the HIV-1 primary isolate DH012.

T. Matthews, Chin-Ho Chen, Chongbin Zhu, 2003, Vaccine.

Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus.

E. De Clercq, Dongwei Kang, Boshi Huang, 2018, European journal of medicinal chemistry.

Optimization of 2,4-diarylanilines as non-nucleoside HIV-1 reverse transcriptase inhibitors.

Li Huang, Chin-Ho Chen, Keduo Qian, 2012, Bioorganic & medicinal chemistry letters.

Role of Porphyromonas gingivalis outer membrane vesicles in oral mucosal transmission of HIV

Chin-Ho Chen, C. Dash, J. S. Goodwin, 2018, Scientific Reports.

Synthesis and proteasome inhibition of lithocholic acid derivatives.

Dominique N. Soroka, Li Huang, Chin-Ho Chen, 2011, Bioorganic & medicinal chemistry letters.

Design and synthesis of naphthoquinone derivatives as antiproliferative agents and 20S proteasome inhibitors.

Li Huang, Chin-Ho Chen, K. Lee, 2012, Bioorganic & medicinal chemistry letters.

New betulinic acid derivatives as potent proteasome inhibitors.

Li Huang, Chin-Ho Chen, Keduo Qian, 2011, Bioorganic & medicinal chemistry letters.

Discovery of novel non-covalent inhibitors selective to the β5-subunit of the human 20S proteasome.

Li Huang, Chin-Ho Chen, Zhiyan Xiao, 2015, European journal of medicinal chemistry.

Structure Optimization of Aloperine Derivatives as HIV-1 Entry Inhibitors.

Zhijun Li, Li Huang, Chin-Ho Chen, 2017, ACS medicinal chemistry letters.

Proteasome regulators: activators and inhibitors.

Li Huang, Chin-Ho Chen, 2009, Current medicinal chemistry.

Oxathiazole-2-one derivative of bortezomib: Synthesis, stability and proteasome inhibition activity

B. Gryder, A. Oyelere, Chin-Ho Chen, 2011 .

Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors.

Hong Lu, Shibo Jiang, Li Huang, 2010, Journal of medicinal chemistry.

The role of dynamin in HIV type 1 Env-mediated cell-cell fusion.

D. Montefiori, Li Huang, Chin-Ho Chen, 2011, AIDS research and human retroviruses.

A N-propionylsulfonamide prodrug of K-5a2 provided improved aqueous solubility and hERG inhibition

Dongwei Kang, C. Pannecouque, P. Zhan, 2020 .

Discovery of diarylpyridine derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Hong Lu, Shibo Jiang, Chin-Ho Chen, 2009, Bioorganic & medicinal chemistry letters.

Role of Human Immunodeficiency Virus (HIV) Type 1 Envelope in the Anti-HIV Activity of the Betulinic Acid Derivative IC9564

Lei Jin, T. Matthews, Chin-Ho Chen, 2001, Antimicrobial Agents and Chemotherapy.

Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents.

Li Huang, Chin-Ho Chen, Keduo Qian, 2009, Journal of medicinal chemistry.

Phenolic diterpenoid derivatives as anti-influenza a virus agents.

Li Huang, Katherine Jung, Chin-Ho Chen, 2015, ACS medicinal chemistry letters.

Identification and synthesis of quinolizidines with anti-influenza a virus activity.

Li Huang, Katherine Jung, Chin-Ho Chen, 2014, ACS medicinal chemistry letters.

DNA Polymerases versus HIV Reverse Transcriptase in AIDS Therapy

Chin-Ho Chen, W. Gao, M. Vazquez-Padua, 1990, Annals of the New York Academy of Sciences.

Quinolizidines as Novel SARS-CoV-2 Entry Inhibitors

Li Huang, Chin-Ho Chen, Lan Xie, 2022, International journal of molecular sciences.

Bioactive ent-isopimarane diterpenoids from Euphorbia neriifolia.

Zhi‐Jun Zhang, Chin-Ho Chen, Rong-Tao Li, 2020, Phytochemistry.

Elimination of HIV-1 Latently Infected Cells by Gnidimacrin and a Selective HDAC Inhibitor.

Wei Li, Li Huang, Chin-Ho Chen, 2018, ACS medicinal chemistry letters.

Discovery of potential dual-target prodrugs of HIV-1 reverse transcriptase and nucleocapsid protein 7.

E. De Clercq, Dongwei Kang, Boshi Huang, 2020, Bioorganic & Medicinal Chemistry Letters.

Gnidimacrin, the Potent Anti-HIV Diterpene Can Eliminate Latent HIV-1 Ex Vivo by Activation of PKC Beta

G. Ferrari, Cliburn Chan, Li Huang, 2016 .

Design, Synthesis, and Mechanism Study of Benzenesulfonamide-containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities.

E. De Clercq, Dongwei Kang, C. Pannecouque, 2020, Journal of medicinal chemistry.

Iridoids and sesquiterpenoids from Valeriana jatamansi and their anti-influenza virus activities.

Chin-Ho Chen, Rong-Tao Li, Hong-mei Li, 2022, Bioorganic chemistry.

Anti-inflammatory and Anti-HIV Compounds from Swertia bimaculata

Chin-Ho Chen, M. Dong, Rong-Tao Li, 2017, Planta Medica.

Design, synthesis, and structure activity relationship analysis of new betulinic acid derivatives as potent HIV inhibitors.

Chin-Ho Chen, K. Lee, S. Morris-Natschke, 2021, European journal of medicinal chemistry.

Synthesis and Structure-Activity Relationship Correlations of Gnidimacrin Derivatives as Potent HIV-1 Inhibitors and HIV Latency Reversing Agents.

Wei Li, K. Koike, Li Huang, 2019, Journal of medicinal chemistry.

Incorporation of Privileged Structures into Bevirimat Can Improve Activity against Wild-Type and Bevirimat-Resistant HIV-1.

Qiong Gu, Chin-Ho Chen, K. Lee, 2016, Journal of medicinal chemistry.

Synthesis and biological evaluation of novel spin labeled 18β-glycyrrhetinic acid derivatives.

Chin-Ho Chen, Keduo Qian, K. Lee, 2012, Bioorganic & medicinal chemistry letters.

Anti-AIDS agents 82: synthesis of seco-(3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) derivatives as novel anti-HIV agents.

Yi Xia, Chin-Ho Chen, Keduo Qian, 2010, Bioorganic & medicinal chemistry.

Anti-AIDS agents 85. Design, synthesis, and evaluation of 1R,2R-dicamphanoyl-3,3-dimethyldihydropyrano-[2,3-c]xanthen-7(1H)-one (DCX) derivatives as novel anti-HIV agents.

Li Huang, Chin-Ho Chen, K. Lee, 2012, European journal of medicinal chemistry.

Anti-AIDS agents 79. Design, synthesis, molecular modeling and structure-activity relationships of novel dicamphanoyl-2',2'-dimethyldihydropyranochromone (DCP) analogs as potent anti-HIV agents.

Hao Zhu, Li Huang, Chin-Ho Chen, 2010, Bioorganic & medicinal chemistry.

Anti-AIDS agents 87. New bio-isosteric dicamphanoyl-dihydropyranochromone (DCP) and dicamphanoyl-khellactone (DCK) analogues with potent anti-HIV activity.

Yi Xia, Hong-shan Liu, Chin-Ho Chen, 2011, Bioorganic & medicinal chemistry letters.

Kleinhospitine E and Cycloartane Triterpenoids from Kleinhovia hospita.

Chin-Ho Chen, K. Lee, S. Morris-Natschke, 2018, Journal of natural products.

Mechanism of action and resistant profile of anti-HIV-1 coumarin derivatives.

Li Huang, Chin-Ho Chen, Donglei Yu, 2005, Virology.

Anti-AIDS agents. 60. Substituted 3'R,4'R-di-O-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP) analogues as potent anti-HIV agents.

A. Brossi, Chin-Ho Chen, K. Lee, 2004, Journal of medicinal chemistry.

Anti-AIDS agents 88. Anti-HIV conjugates of betulin and betulinic acid with AZT prepared via click chemistry.

Chin-Ho Chen, Keduo Qian, K. Lee, 2012, Tetrahedron letters.

Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor Agents: Optimization of Diarylanilines with High Potency against Wild-Type and Rilpivirine-Resistant E138K Mutant Virus.

Weifan Zheng, Shibo Jiang, Na Liu, 2016, Journal of medicinal chemistry.

LC-MS Identification, Isolation, and Structural Elucidation of Anti-HIV Tigliane Diterpenoids from Wikstroemia lamatsoensis.

Wei Li, K. Koike, Li Huang, 2021, Journal of natural products.

Aloperine and Its Derivatives as a New Class of HIV-1 Entry Inhibitors.

Li Huang, Chin-Ho Chen, Z. Dang, 2016, ACS medicinal chemistry letters.

Carbazole Alkaloids from Clausena anisum-olens: Isolation, Characterization, and Anti-HIV Evaluation

Chin-Ho Chen, K. Lee, S. Morris-Natschke, 2019, Molecules.

Hyperdioxanes, dibenzo-1,4-dioxane derivatives from the roots of Hypericum ascyron

D. Tsuji, Chin-Ho Chen, K. Lee, 2021, Journal of Natural Medicines.

Synthesis and proteasome inhibition of glycyrrhetinic acid derivatives.

Li Huang, Chin-Ho Chen, Keduo Qian, 2008, Bioorganic & Medicinal Chemistry.

The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV

David E. Martin, Chin-Ho Chen, K. Lee, 2005, Expert opinion on investigational drugs.

Rapid Recognition and Targeted Isolation of Anti-HIV Daphnane Diterpenes from Daphne genkwa Guided by UPLC-MSn.

Chin-Ho Chen, K. Lee, S. Morris-Natschke, 2019, Journal of natural products.

Anti-AIDS agents 81. Design, synthesis, and structure-activity relationship study of betulinic acid and moronic acid derivatives as potent HIV maturation inhibitors.

Li Huang, Chin-Ho Chen, Keduo Qian, 2010, Journal of medicinal chemistry.

The role of the third β strand in gp120 conformation and neutralization sensitivity of the HIV-1 primary isolate DH012

C. H. Chen, L. Zhu, T. Matthews, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Anti-AIDS agents 49. Synthesis, anti-HIV, and anti-fusion activities of IC9564 analogues based on betulinic acid.

Chin-Ho Chen, K. Lee, Y. Kashiwada, 2002, Journal of medicinal chemistry.

Daphneodorins A-C, Anti-HIV Gnidimacrin Related Macrocyclic Daphnane Orthoesters from Daphne odora.

Wei Li, K. Koike, Chin-Ho Chen, 2019, Organic letters.

Stelleralides A-C, novel potent anti-HIV daphnane-type diterpenoids from Stellera chamaejasme L.

Wei Li, K. Koike, Chin-Ho Chen, 2011, Organic letters.

Isolation, Structural Elucidation, and Anti-HIV Activity of Daphnane Diterpenoids from Daphne odora.

Wei Li, K. Koike, Li Huang, 2020, Journal of natural products.

Fluorinated betulinic acid derivatives and evaluation of their anti-HIV activity.

Li Huang, Chin-Ho Chen, K. Lee, 2016, Bioorganic & medicinal chemistry letters.

New betulinic acid derivatives for bevirimat-resistant human immunodeficiency virus type-1.

Li Huang, Chin-Ho Chen, Z. Dang, 2013, Journal of medicinal chemistry.

Moronic Acid and Other Triterpene Derivatives as Novel Potent Anti-HIV Agents 1

Yoshiki, F. Chang, Li Huang, 2008 .

Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents.

F. Chang, Li Huang, Chin-Ho Chen, 2006, Journal of medicinal chemistry.

Conformation of gp120 determines the sensitivity of HIV-1 DH012 to the entry inhibitor IC9564.

C. Labranche, Li Huang, Chin-Ho Chen, 2004, Virology.

Bifunctional Anti-Human Immunodeficiency Virus Type 1 Small Molecules with Two Novel Mechanisms of Action

C. Aiken, Li Huang, Chin-Ho Chen, 2004, Antimicrobial Agents and Chemotherapy.

Tigliane-Type Diterpene Esters from the Fruits of Shirakiopsis indica and Their Anti-HIV Activity.

Chin-Ho Chen, K. Lee, Y. Kashiwada, 2022, Journal of natural products.

Terpenes from Euphorbia antiquorum and Their in Vitro Anti‐HIV Activity

Chin-Ho Chen, M. Dong, Rong-Tao Li, 2018, Chemistry & biodiversity.

Design, synthesis, and biologic evaluation of novel galloyl derivatives as HIV‐1 RNase H inhibitors

Peng Zhan, Jacob Kongsted, Luis Menéndez-Arias, 2019, Chemical biology & drug design.

New Phorbol Ester Derivatives as Potent Anti-HIV Agents.

Chin-Ho Chen, K. Lee, Lei Zhao, 2021, Bioorganic & medicinal chemistry letters.

Synthesis and anti-HIV activity of bi-functional betulinic acid derivatives.

Li Huang, Chin-Ho Chen, K. Lee, 2006, Bioorganic & medicinal chemistry.

Two Small Molecules Block Oral Epithelial Cell Invasion by Porphyromons gingivalis

Li Huang, Chin-Ho Chen, J. S. Goodwin, 2016, PloS one.

Design and Synthesis of Quinolizidine Derivatives as Influenza Virus and HIV-1 Inhibitors.

Zhijun Li, Li Huang, Chin-Ho Chen, 2020, Current medicinal chemistry.

Synthesis of new 2'-deoxy-2'-fluoro-4'-azido nucleoside analogues as potent anti-HIV agents.

Weidong Hu, Chin-Ho Chen, Keduo Qian, 2011, European journal of medicinal chemistry.

Synthesis and anti-HIV activity of 2'-deoxy-2'-fluoro-4'-C-ethynyl nucleoside analogs.

Chin-Ho Chen, Keduo Qian, K. Lee, 2010, Bioorganic & medicinal chemistry letters.

Expression of Deoxynucleotide Carrier Is Not Associated with the Mitochondrial DNA Depletion Caused by Anti-HIV Dideoxynucleoside Analogs and Mitochondrial dNTP Uptake

C. Leung, Chin-Ho Chen, W. Lam, 2005, Molecular Pharmacology.

Novel Betulinic Acid-Nucleoside Hybrids with Potent Anti-HIV Activity.

Yanli Wang, Chin-Ho Chen, K. Lee, 2020, ACS medicinal chemistry letters.

Synthesis and anti‐HIV Activity of 2′‐Deoxy‐2′‐fluoro‐4′‐C‐ethynyl Nucleoside Analogues.

Chin-Ho Chen, Keduo Qian, K. Lee, 2010 .

Betulinic Acid Derivatives That Target gp120 and Inhibit Multiple Genetic Subtypes of Human Immunodeficiency Virus Type 1

D. Montefiori, Zhijun Li, Li Huang, 2007, Antimicrobial Agents and Chemotherapy.

Conjugates of betulin derivatives with AZT as potent anti-HIV agents.

Chin-Ho Chen, Keduo Qian, K. Lee, 2010, Bioorganic & medicinal chemistry.

Fimbriae-mediated outer membrane vesicle production and invasion of Porphyromonas gingivalis

S. Pratap, Chin-Ho Chen, J. S. Goodwin, 2014, MicrobiologyOpen.

Role of Porphyromonas gingivalis outer membrane vesicles in oral mucosal transmission of HIV

Chin-Ho Chen, C. Dash, J. S. Goodwin, 2018, Scientific Reports.

Discovery and synthesis of novel beesioside I derivatives with potent anti-HIV activity.

Li Huang, Chin-Ho Chen, K. Lee, 2019, European journal of medicinal chemistry.

Structural Rearrangements in the Transmembrane Glycoprotein after Receptor Binding

D. Bolognesi, T. Matthews, M. Greenberg, 1994, Immunological reviews.

Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities.

P. Zhan, Xinyong Liu, Chin-Ho Chen, 2020, European journal of medicinal chemistry.

Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties.

Peng Zhan, Jian Zhang, F. J. Luque, 2019, Journal of medicinal chemistry.

Functional Advantages of Porphyromonas gingivalis Vesicles

Chin-Ho Chen, J. S. Goodwin, Bing-yan Wang, 2015, PloS one.

Inhibition of Human Immunodeficiency Virus Type 1 Entry by a Binding Domain of Porphyromonas gingivalis Gingipain

Chin-Ho Chen, Jie Wu, W. Lai, 2006, Antimicrobial Agents and Chemotherapy.

Identification, structural modification, and dichotomous effects on human immunodeficiency virus type 1 (HIV-1) replication of ingenane esters from Euphorbia kansui.

Wei Li, K. Koike, Li Huang, 2018, European journal of medicinal chemistry.

Isolation, structure determination, and anti-HIV evaluation of tigliane-type diterpenes and biflavonoid from Stellera chamaejasme.

Wei Li, K. Koike, Chin-Ho Chen, 2013, Journal of natural products.

Picomolar Dichotomous Activity of Gnidimacrin Against HIV-1

Jie Yu, Li Huang, Chin-Ho Chen, 2011, PloS one.

Blocking HIV-1 entry by a gp120 surface binding inhibitor.

A. Hamilton, Chin-Ho Chen, L. Tsou, 2012, Bioorganic & medicinal chemistry letters.

Noncytolytic CD8 T cell-mediated suppression of HIV replication

D. Bolognesi, K. Weinhold, M. Greenberg, 2004, Springer Seminars in Immunopathology.

Gnidimacrin, a Potent Anti-HIV Diterpene, Can Eliminate Latent HIV-1 Ex Vivo by Activation of Protein Kinase C β.

Wei Li, G. Ferrari, Cliburn Chan, 2015, Journal of medicinal chemistry.

Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.

Bingjie Qin, Lan Xie, Li Huang, 2012, Journal of medicinal chemistry.

Carolignans from the Aerial Parts of Euphorbia sikkimensis and Their Anti-HIV Activity.

Qiong Gu, Jun Xu, Chin-Ho Chen, 2016, Journal of natural products.

Paliasanines A-E, 3,4-Methylenedioxyquinoline Alkaloids Fused with a Phenyl-14-oxabicyclo[3.2.1]octane Unit from Melochia umbellata var. deglabrata.

S. Fukuyoshi, Chin-Ho Chen, K. Lee, 2020, Journal of natural products.

Design, synthesis, and antiviral activity of phenylalanine derivatives as HIV-1 capsid inhibitors.

Dongwei Kang, P. Zhan, Xinyong Liu, 2021, Bioorganic & medicinal chemistry.

Anti-AIDS agents 90. novel C-28 modified bevirimat analogues as potent HIV maturation inhibitors.

Li Huang, Chin-Ho Chen, Keduo Qian, 2012, Journal of medicinal chemistry.

Betulinic acid derivatives as human immunodeficiency virus type 2 (HIV-2) inhibitors.

Li Huang, Chin-Ho Chen, Z. Dang, 2009, Journal of medicinal chemistry.

Human Immunodeficiency Virus Type 1 Resistance to the Small Molecule Maturation Inhibitor 3-O-(3′,3′-Dimethylsuccinyl)-Betulinic Acid Is Conferred by a Variety of Single Amino Acid Substitutions at the CA-SP1 Cleavage Site in Gag

C. Aiken, Chin-Ho Chen, Chin Ho Chen, 2006, Journal of Virology.

Inhibition of HIV-1 Maturation via Drug Association with the Viral Gag Protein in Immature HIV-1 Particles*

C. Aiken, Li Huang, Chin-Ho Chen, 2005, Journal of Biological Chemistry.

Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Replication by Specific Targeting of the Final Step of Virion Maturation

C. Aiken, C. Lundquist, B. Forshey, 2004, Journal of Virology.

Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors

Dongwei Kang, P. Zhan, Xinyong Liu, 2019, RSC advances.

Potent Anti-HIV Ingenane Diterpenoids from Euphorbia ebracteolata.

Chin-Ho Chen, K. Lee, Dao-feng Chen, 2019, Journal of natural products.

Flavonoids Isolated from Heat-Processed Epimedium koreanum and Their Anti-HIV-1 Activities

Chin-Ho Chen, K. Lee, Cheng Zhou, 2015 .

HIV-1 maturation inhibitors: An update

Li Huang, Chin-Ho Chen, Z. Dang, 2009, Drugs of the future.

Identification of anti-HIV macrocyclic daphnane orthoesters from Wikstroemia ligustrina by LC–MS analysis and phytochemical investigation

Wei Li, K. Koike, Minami Tsuji, 2021, Journal of natural medicines.

Anti-HIV Tigliane-Type Diterpenoids from the Aerial Parts of Wikstroemia lichiangensis.

Li Huang, Chin-Ho Chen, Gang Chen, 2022, Journal of natural products.

Anti-HIV tigliane diterpenoids from Reutealis trisperma.

Chin-Ho Chen, K. Lee, S. Morris-Natschke, 2020, Phytochemistry.

Anti-HIV Tigliane Diterpenoids from Wikstroemia scytophylla.

Wei Li, K. Koike, Minami Tsuji, 2020, Journal of natural products.

Daphnepedunins A-F, Anti-HIV Macrocyclic Daphnane Orthoester Diterpenoids from Daphne pedunculata.

Li Huang, Chin-Ho Chen, I. Azumaya, 2022, Journal of natural products.

Anti-HIV Macrocyclic Daphnane Orthoesters with an Unusual Macrocyclic Ring from Edgeworthia chrysantha.

Wei Li, K. Koike, Li Huang, 2022, Journal of natural products.

Stelleralides D-J and Anti-HIV Daphnane Diterpenes from Stellera chamaejasme.

Chin-Ho Chen, K. Lee, Dao-feng Chen, 2015, Journal of natural products.

Molecular targets of anti-HIV-1 triterpenes.

Li Huang, Chin-Ho Chen, 2002, Current drug targets. Infectious disorders.

Diterpenes from the stem bark of Euphorbia neriifolia and their in vitro anti-HIV activity.

Chin-Ho Chen, Rong-Tao Li, Dan Liu, 2018, Phytochemistry.

Identification of gp120 Regions Targeted by a Highly Potent Neutralizing Antiserum Elicited in a Chimpanzee Inoculated with a Primary Human Immunodeficiency Virus Type 1 Isolate

M. Cho, T. Matthews, Chin-Ho Chen, 2000, Journal of Virology.

Optimization of the Antiviral Potency and Lipophilicity of Halogenated 2,6‐Diarylpyridinamines as a Novel Class of HIV‐1 NNRTIS

Bingjie Qin, Lan Xie, Shibo Jiang, 2014, ChemMedChem.

Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Hong Lu, Shibo Jiang, Xiao‐Feng Wang, 2010, Journal of medicinal chemistry.

Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library.

Fangfang Zhang, Peng Zhan, Ye Tian, 2018, European journal of medicinal chemistry.

Potential drug targets on the HIV-1 envelope glycoproteins, gp120 and gp41.

Li Huang, Chin-Ho Chen, Linda Zhang, 2003, Current pharmaceutical design.

The role of cytoplasmic deoxycytidine kinase in the mitochondrial effects of the anti-human immunodeficiency virus compound, 2',3'-dideoxycytidine.

C. H. Chen, Y. Cheng, Chin-Ho Chen, 1992, The Journal of biological chemistry.

Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine.

C. H. Chen, Y. Cheng, Chin-Ho Chen, 1989, The Journal of biological chemistry.

Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.

C. H. Chen, Y. Cheng, Chin-Ho Chen, 1991, Molecular pharmacology.

A molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: implication for viral fusion

D. Bolognesi, T. Matthews, C. McDanal, 1995, Journal of virology.

Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri

Chin-Ho Chen, Rong-Tao Li, Xue-Wei Zhao, 2016, Archives of pharmacal research.

Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri

Chin-Ho Chen, Rong-Tao Li, Xue-Wei Zhao, 2016, Archives of Pharmacal Research.

Anti-AIDS agents. 15. Synthesis and anti-HIV activity of dihydroseselins and related analogs.

A. McPhail, K. Lee, Li Huang, 1994, Journal of medicinal chemistry.

Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors.

Hong Lu, Shibo Jiang, Li Huang, 2010, Journal of medicinal chemistry.

Optimization of 2,4-diarylanilines as non-nucleoside HIV-1 reverse transcriptase inhibitors.

Li Huang, Chin-Ho Chen, Keduo Qian, 2012, Bioorganic & medicinal chemistry letters.

Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Hong Lu, Shibo Jiang, Xiao‐Feng Wang, 2010, Journal of medicinal chemistry.

Induction and Characterization of Neutralizing Antibodies against a Human Immunodeficiency Virus Type 1 Primary Isolate

Lei Jin, T. Matthews, Chin-Ho Chen, 2001, Journal of Virology.

Anti-AIDS agents--XXVII. Synthesis and anti-HIV activity of betulinic acid and dihydrobetulinic acid derivatives.

K. Lee, Chin-Ho Chen, Y. Kashiwada, 1997, Bioorganic & medicinal chemistry.

Identification and synthesis of quinolizidines with anti-influenza a virus activity.

Li Huang, Katherine Jung, Chin-Ho Chen, 2014, ACS medicinal chemistry letters.

Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents.

K. Lee, Chin-Ho Chen, K. Lee, 1998, Journal of medicinal chemistry.

Discovery of novel diarypyrimidine derivatives bearing six-membered non-aromatic heterocycles as potent HIV-1 NNRTIs with improved anti-resistance and drug-like profiles.

E. De Clercq, Dongwei Kang, Boshi Huang, 2023, European journal of medicinal chemistry.