J. Vitorica

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Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

E. Gavilan, D. Ruano, C. Pintado, 2012, Journal of Neuroinflammation.

Neuroinflammation in Alzheimer's disease

O. Garaschuk, K. Herrup, D. Brooks, 2015, The Lancet Neurology.

Asp32 and Asp228 determine the selective inhibition of BACE1 as shown by docking and molecular dynamics simulations.

M. Rosales-Hernández, J. Correa-Basurto, A. Gutiérrez, 2016, European journal of medicinal chemistry.

Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum.

A. Gutiérrez, J. Vitorica, Javier Vitorica, 2014, Journal of Alzheimer's disease : JAD.

Absence of association between δ and γ2 subunits in native GABAA receptors from rat brain

D. Ruano, J. Vitorica, F. Araujo, 1998 .

Regional differences in the enhancement by GABA of [3H]zolpidem binding to ω1 sites in rat brain membranes and sections

J. Bénavidès, D. Ruano, J. Vitorica, 1993, Brain Research.

Heterogeneity in the Allosteric Interaction Between the γ‐Aminobutyric Acid (GABA) Binding Site and Three Different Benzodiazepine Binding Sites of the GABAA/Benzodiazepine Receptor Complex in the Rat Nervous System

J. Cano, D. Ruano, J. Vitorica, 1992, Journal of neurochemistry.

Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells’ degeneration induced by inflammatory processes after lipopolysaccharide injection

D. Ruano, C. Pintado, M. P. Gavilan, 2006, Neuroscience.

Increased levels of tumour necrosis factor alpha (TNFα) but not transforming growth factor‐beta 1 (TGFβ1) are associated with the severity of congenital hydrocephalus in the hyh mouse

M. Cifuentes, J. Pérez-Fígares, A. Jiménez, 2014, Neuropathology and applied neurobiology.

GABAA and α-Amino-3-hydroxy-5-methylsoxazole-4-propionate Receptors Are Differentially Affected by Aging in the Rat Hippocampus*

O. Bergis, D. Ruano, J. Vitorica, 2000, The Journal of Biological Chemistry.

Metabolomic screening of regional brain alterations in the APP/PS1 transgenic model of Alzheimer's disease by direct infusion mass spectrometry.

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2015, Journal of pharmaceutical and biomedical analysis.

Combined Reviewers ' comments : Compound Identification : 1

J. Ariza, J. Gómez-Ariza, T. García-Barrera, 2014 .

Galectin-3, A Novel Endogenous Trem2 Ligand, Regulates Inflammatory Response and Aβ Fibrilation in Alzheimer’s Disease

E. Englund, S. Linse, T. Deierborg, 2018 .

The pentose phosphate cycle is regulated by NADPH/NADP ratio in rat liver.

I. Fabregat, J. Vitorica, J. Satrústegui, 1985, Archives of biochemistry and biophysics.

Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis

A. Gutiérrez, J. Vitorica, Elisabeth Sánchez-Mejías, 2022, International journal of molecular sciences.

Elsevier Editorial System(tm) for Journal of Pharmaceutical and Biomedical Analysis Manuscript Draft Manuscript Number: JPBA-D-14-01586R1 Title: APPLICATION OF METABOLOMICS BASED ON DIRECT MASS SPECTROMETRY ANALYSIS FOR THE ELUCIDATION OF ALTERED METABOLIC PATHWAYS IN SERUM FROM THE APP/PS1 TRANSGEN

M. Eberlin, J. Ariza, J. Gómez-Ariza, 2015 .

Application of metabolomics based on direct mass spectrometry analysis for the elucidation of altered metabolic pathways in serum from the APP/PS1 transgenic model of Alzheimer's disease.

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2015, Journal of pharmaceutical and biomedical analysis.

J. Vitorica, J. Satrústegui, A. Machado, 1981, Neurochemical Research.

Impairment of glutamate uptake and absence of alterations in the energy-transducing ability of old rat brain mitochondria

J. Vitorica, J. Satrústegui, A. Machado, 1985, Mechanisms of Ageing and Development.

Membrane lipid modifications and therapeutic effects mediated by hydroxydocosahexaenoic acid on Alzheimer's disease.

P. Escribá, F. Goñi, X. Busquets, 2014, Biochimica et biophysica acta.

Implication of dopamine transporter system on 1-methyl-4-phenylpyridinium and rotenone effect in striatal synaptosomes.

J. Cano, J. Vitorica, A. Machado, 1995, European journal of pharmacology.

The influence of age on the calcium-efflux pathway and matrix calcium buffering power in brain mitochondria.

J. Vitorica, J. Satrústegui, 1986, Biochimica et biophysica acta.

Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases

J. M. Monje, M. Artal-Sanz, M. Muñoz, 2019, bioRxiv.

Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer’s disease

K. Blennow, R. Sánchez-Valle, U. Andréasson, 2022, Acta Neuropathologica.

Cytosolic free calcium levels increase with age in rat brain synaptosomes

J. Vitorica, J. Satrústegui, Alberto Martínez, 1988, Neuroscience Letters.

Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model*

D. Ruano, A. Gutiérrez, J. Vitorica, 2011, The Journal of Biological Chemistry.

Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer’s disease

K. Blennow, R. Sánchez-Valle, U. Andréasson, 2022, Acta Neuropathologica.

Comparison between developmental and senescent changes in enzyme activities linked to energy metabolism in rat heart

J. Cano, J. Vitorica, J. Satrústegui, 1981, Mechanisms of Ageing and Development.

Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease

E. Galea, J. Comella, A. Gutiérrez, 2017, Glia.

Pharmacological properties of the GABA(A) receptor complex from brain regions of (hypoemotional) Roman high- and (hyperemotional) low-avoidance rats.

A. Tobeña, R. M. Escorihuela, D. Ruano, 1998, European journal of pharmacology.

Activity-Dependent Neuroprotective Protein (ADNP) Expression in the Amyloid Precursor Protein/Presenilin 1 Mouse Model of Alzheimer’s Disease

D. Pozo, I. Gozes, A. Gutiérrez, 2010, Journal of Molecular Neuroscience.

Animal and Cellular Models of Alzheimer’s Disease: Progress, Promise, and Future Approaches

F. LaFerla, A. Gutiérrez, J. Vitorica, 2021, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Distribution of the γ-aminobutyric acidA receptor complex alpha 5 subunit in chick brain. An immunocytochemical and autoradiographic study

J. Vitorica, C. C. Gimenes, F. Araujo, 2000, Neuroscience Letters.

Native gamma-aminobutyric acid type A receptors from rat hippocampus, containing both alpha 1 and alpha 5 subunits, exhibit a single benzodiazepine binding site with alpha 5 pharmacological properties.

D. Ruano, J. Vitorica, F. Araujo, 1999, The Journal of pharmacology and experimental therapeutics.

Native g-Aminobutyric Acid Type A Receptors from Rat Hippocampus, Containing Both a1 and a5 Subunits, Exhibit a Single Benzodiazepine Binding Site with a5 Pharmacological

D. Ruano, J. Vitorica, F. Araujo, 1999 .

Molecular and Pharmacological Characterization of Native Cortical γ-Aminobutyric AcidA Receptors Containing Both α1 and α3 Subunits*

H. Schoemaker, J. Bénavidès, D. Ruano, 1996, The Journal of Biological Chemistry.

Comparative autoradiographic distribution of central ω (benzodiazepine) modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem

J. Bénavidès, B. Scatton, D. Ruano, 1993, Brain Research.

D. Ruano, J. Vitorica, F. Araujo, 1996, Brain Research.

Reactive astrocyte nomenclature, definitions, and future directions

Kira E. Poskanzer, B. Khakh, C. Rose, 2021, Nature Neuroscience.

The role of ADP in the modulation of the calcium-efflux pathway in rat brain mitochondria.

J. Vitorica, J. Satrústegui, 1985, The Biochemical journal.

Expression of α5 GABAA receptor subunit in developing rat hippocampus

J. F. López-Téllez, D. Ruano, A. Gutiérrez, 2004 .

Postnatal development of the alpha1 containing GABAA receptor subunit in rat hippocampus.

J. F. López-Téllez, D. Ruano, A. Gutiérrez, 2004, Brain research. Developmental brain research.

Research report Postnatal development of the a1 containing GABA A receptor subunit in rat hippocampus

J. F. López-Téllez, D. Ruano, A. Gutiérrez, 2004 .

Expression of alpha 5 GABAA receptor subunit in developing rat hippocampus.

J. F. López-Téllez, D. Ruano, A. Gutiérrez, 2004, Brain research. Developmental brain research.

Differential expression of the short and long forms of the gamma 2 subunit of the GABAA/benzodiazepine receptors.

A. Gutiérrez, Z. Khan, J. Vitorica, 1994, Brain research. Molecular brain research.

Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1×APP transgenic model of Alzheimer's disease

J. F. López-Téllez, Z. Khan, D. Ruano, 2006, Neurobiology of Aging.

The GABAA/benzodiazepine receptor complex in rat brain neuronal cultures. Characterization by immunoprecipitation

J. Vitorica, Dongeun Park, A. D. Blas, 1990, Brain Research.

Characterization with Antibodies of the γ‐Aminobutyric AcidA/Benzodiazepine Receptor Complex During Development of the Rat Brain

J. Vitorica, Dongeun Park, G. Chin, 1990, Journal of neurochemistry.

Distinct disease‐sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients

A. Gutiérrez, J. Vitorica, J. Davila, 2019, Brain pathology.

Should We Open Fire on Microglia? Depletion Models as Tools to Elucidate Microglial Role in Health and Alzheimer’s Disease

A. Gutiérrez, J. Vitorica, M. Vizuete, 2021, International journal of molecular sciences.

Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease

E. Galea, A. Gutiérrez, J. Vitorica, 2020, Glia.

Immunohistochemical localization of GABAA receptors in the retina of the new world primate Saimiri sciureus

H. Karten, T. Hughes, J. Vitorica, 1989, Visual Neuroscience.

Metabolic implications of ageing: changes in activities of key lipogenic and gluconeogenic enzymes in the aged rat liver.

J. Vitorica, J. Satrústegui, A. Machado, 1981, Enzyme.

Immunocytochemical localization of GABAA receptors in goldfish and chicken retinas

S. Yazulla, K. Studholme, J. Vitorica, 1989, The Journal of comparative neurology.

Involvement of mitochondria in the age-dependent decrease in calcium uptake of rat brain synaptosomes

J. Vitorica, Jorgina Satru´stegui, 1986, Brain Research.

Age‐Dependent Variations in Peroxide‐Utilizing Enzymes from Rat Brain Mitochondria and Cytoplasm

J. Vitorica, J. Satrústegui, A. Machado, 1984, Journal of neurochemistry.

Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-β-Induced Neuronal Death.

R. Hervás, J. Vitorica, I. Torres Alemán, 2016, Journal of Alzheimer's disease : JAD.

Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease

A. Gutiérrez, J. Vitorica, J. Davila, 2020, International journal of molecular sciences.

High throughput multiorgan metabolomics in the APP/PS1 mouse model of Alzheimer's disease

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2015, Electrophoresis.

Deciphering metabolic abnormalities associated with Alzheimer's disease in the APP/PS1 mouse model using integrated metabolomic approaches.

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2015, Biochimie.

Metabolomic research on the role of interleukin-4 in Alzheimer’s disease

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2015, Metabolomics.

Monoclonal antibodies and conventional antisera to the GABAA receptor/benzodiazepine receptor/Cl- channel complex

J. Vitorica, A. D. de Blas, A. D. De Blas, 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1

J. López-Barneo, Antonio Heras-Garvin, A. Serrano‐Pozo, 2021, Nature Aging.

Use of human pluripotent stem cell-derived cells for neurodegenerative disease modeling and drug screening platform.

A. Gutiérrez, J. Vitorica, J. García-León, 2019, Future medicinal chemistry.

Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

Sara Linse, Elisabet Englund, Antonia Gutierrez, 2019, Acta Neuropathologica.

Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells

M. Cifuentes, A. Jiménez, M. García-Martín, 2020, Stem Cell Research & Therapy.

Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology

I. Torres-Aleman, D. Dávila, C. Guaza, 2012, Molecular Psychiatry.

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

Antonia Gutierrez, Raquel Sanchez-Varo, J. García-Verdugo, 2011, Acta Neuropathologica.

Disruption of Amyloid Plaques Integrity Affects the Soluble Oligomers Content from Alzheimer Disease Brains

J. Moyano, A. Gutiérrez, J. Vitorica, 2014, PloS one.

Microglia in Alzheimer’s Disease: Activated, Dysfunctional or Degenerative

A. Gutiérrez, J. Vitorica, J. Davila, 2018, Front. Aging Neurosci..

Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration

A. Gutiérrez, J. Vitorica, J. Davila, 2016, Acta Neuropathologica.

Neuroinfl ammation in Alzheimer's disease

O. Garaschuk, K. Herrup, D. Brooks, 2015 .

Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology

A. Gutiérrez, J. Vitorica, Raquel Sánchez‐Varo, 2018, Front. Cell. Neurosci..

Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease

C. Soto, F. Court, A. Gutiérrez, 2021, bioRxiv.

Metabolomics reveals significant impairments in the immune system of the APP/PS1 transgenic mice of Alzheimer's disease

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2015, Electrophoresis.

In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology

A. Gutiérrez, J. Vitorica, J. Davila, 2013, Acta neuropathologica communications.

Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic

D. Ruano, A. Gutiérrez, J. Vitorica, 2008, The Journal of Neuroscience.

Rat hippocampal GABAergic molecular markers are differentially affected by ageing

D. Ruano, A. Gutiérrez, J. Vitorica, 2003, Journal of neurochemistry.

Purification of the γ‐Aminobutyric AcidA/Benzodiazepine Receptor Complex by Immunoaffinity Chromatography

J. Vitorica, Dongeun Park, G. Tous, 1991, Journal of neurochemistry.

Region-specific metabolic alterations in the brain of the APP/PS1 transgenic mice of Alzheimer's disease.

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2014, Biochimica et biophysica acta.

Metabolomic investigation of systemic manifestations associated with Alzheimer's disease in the APP/PS1 transgenic mouse model.

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2015, Molecular bioSystems.

Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis

A. Gutiérrez, J. Vitorica, J. Davila, 2021, Frontiers in Neuroscience.

Extracellular amyloid-beta and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1(M146L)/APP(751SL) mice.

M. Romero-Acebal, D. Ruano, A. Gutiérrez, 2009, Journal of Alzheimer's disease : JAD.

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

Antonia Gutierrez, Raquel Sanchez-Varo, A. Gutiérrez, 2012, Molecular Neurodegeneration.

Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model

A. Gutiérrez, J. Vitorica, J. Davila, 2020, Scientific Reports.

Cytotoxicity and Effects on the Synapsis Induced by Pure Cylindrospermopsin in an E17 Embryonic Murine Primary Neuronal Culture in a Concentration- and Time-Dependent Manner

M. Hinojosa, Á. Jos, A. Cameán, 2022, Toxins.

Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice

G. Perea, M. Vila, E. Galea, 2020, Molecular Neurodegeneration.

Molecular and cellular characterization of the age‐related neuroinflammatory processes occurring in normal rat hippocampus: potential relation with the loss of somatostatin GABAergic neurons

D. Ruano, C. Pintado, A. Gutiérrez, 2007, Journal of neurochemistry.

Title Neuroinflammation in Alzheimer ' s disease Permalink

K. Herrup, C. Holmes, T. Wyss-Coray, 2015 .

Cellular environment facilitates protein accumulation in aged rat hippocampus

D. Ruano, J. Vitorica, A. Castaño, 2006, Neurobiology of Aging.

Differential effects of age on the pathways of calcium influx into nerve terminals

J. Vitorica, J. Satrústegui, E. Bogónez, 1987, Brain Research.

Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases

Ana M. Brokate-Llanos, M. Muñoz, M. Venegas-Calerón, 2021, Nature Communications.

Expression of Gls and Gls2 glutaminase isoforms in astrocytes

M. Norenberg, A. Gutiérrez, J. Vitorica, 2015, Glia.

Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition

E. Gavilan, D. Ruano, C. Pintado, 2009, Aging cell.

Reduction of K+‐Stimulated 45Ca2+ Influx in Synaptosomes with Age Involves Inactivating and Noninactivating Calcium Channels and Is Correlated with Temporal Modifications in Protein Dephosphorylation

A. Martínez-Serrano, J. Vitorica, J. Satrústegui, 1989, Journal of neurochemistry.

Toward a New Concept of Alzheimer's Disease Models: A Perspective from Neuroinflammation.

A. Gutiérrez, J. Vitorica, 2018, Journal of Alzheimer's disease : JAD.

GABAA receptor subunit expression changes in the rat cerebellum and cerebral cortex during aging.

A. Gutiérrez, Z. Khan, D. Ruano, 1997, Brain research. Molecular brain research.

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

A. Gutiérrez, J. Vitorica, J. Davila, 2012, Molecular Neurodegeneration.

Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells

M. Cifuentes, A. Jiménez, M. García-Martín, 2020, Stem Cell Research & Therapy.

Calretinin interneurons are early targets of extracellular amyloid-beta pathology in PS1/AbetaPP Alzheimer mice hippocampus.

M. Romero-Acebal, D. Ruano, A. Gutiérrez, 2010, Journal of Alzheimer's disease : JAD.

Localization of the GABAA receptor in the rat brain with a monoclonal antibody to the 57,000 Mr peptide of the GABAA receptor/benzodiazepine receptor/Cl- channel complex

J. Vitorica, A. D. de Blas, P. Friedrich, 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death

J. Comella, A. Gutiérrez, J. Vitorica, 2015, Cell Death and Disease.

Generation of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated by Mesenchymal Stem Cell Therapy

D. Limbrick, T. Iglesias, R. Ramírez-Lorca, 2023, International journal of molecular sciences.

A. Gutiérrez, Z. Khan, D. Ruano, 1996, Neuroscience.

Non-productive angiogenesis disassembles Aß plaque-associated blood vessels

Luis M. Escudero, A. Pascual, F. de Castro, 2021, Nature Communications.

D. Ruano, J. Vitorica, A. Castaño, 2009, Journal of neurochemistry.

Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease

J. García-Verdugo, A. Gutiérrez, J. Vitorica, 2017, Scientific Reports.

Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo

J. López-Barneo, Antonio Heras-Garvin, A. Serrano‐Pozo, 2017, PloS one.

Regional difference in inflammatory response to LPS-injection in the brain: Role of microglia cell density

D. Ruano, C. Pintado, Luisa García-Cuervo, 2011, Journal of Neuroimmunology.

Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.

J. Cano, D. Ruano, J. Vitorica, 1991, The Journal of pharmacology and experimental therapeutics.

Aging‐Associated Changes in the Pharmacological Properties of the Benzodiazepine (ω) Receptor Isotypes in the Rat Hippocampus

D. Ruano, J. Vitorica, A. Machado, 1995, Journal of neurochemistry.

Absence of modifications of the pharmacological properties of the GABAA receptor complex during aging, as assessed in 3- and 24-month-old rat cerebral cortex.

D. Ruano, J. Vitorica, A. Machado, 1993, European journal of pharmacology.

Molecular heterogeneity of the type I GABAA/benzodiazepine receptor complex.

Z. Khan, D. Ruano, J. Vitorica, 1994, European Journal of Pharmacology.

Prevalence between different α subunits performing the benzodiazepine binding sites in native heterologous GABAA receptors containing the α2 subunit

D. Ruano, J. Vitorica, F. Araujo, 2001 .

Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer’s disease hippocampus

A. Gutiérrez, J. Vitorica, M. Vizuete, 2023, Acta Neuropathologica Communications.

Inter‐individual variability in the expression of the mutated form of hPS1M146L determined the production of Aβ peptides in the PS1xAPP transgenic mice

D. Ruano, A. Gutiérrez, J. Vitorica, 2007, Journal of neuroscience research.

Toward a New Concept of Alzheimer's Disease Models: A Perspective from Neuroinflammation.

A. Gutiérrez, J. Vitorica, 2018, Journal of Alzheimer's disease : JAD.

Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases

Ana M. Brokate-Llanos, M. Muñoz, M. Venegas-Calerón, 2021, Nature Communications.

Expression of Gls and Gls2 glutaminase isoforms in astrocytes

M. Norenberg, A. Gutiérrez, J. Vitorica, 2015, Glia.

Rapid postnatal developmental changes in the passive proton permeability of the inner membrane in rat liver mitochondria.

J. Vitorica, J. Satrústegui, J. Cuezva, 1990, Journal of biochemistry.

Neuroinflammation in Alzheimer's disease

O. Garaschuk, K. Herrup, D. Brooks, 2015, The Lancet Neurology.

Neuroinflammation in Alzheimer's disease

O. Garaschuk, K. Herrup, D. Brooks, 2015, The Lancet Neurology.

Metabolomic investigation of systemic manifestations associated with Alzheimer's disease in the APP/PS1 transgenic mouse model.

J. Gómez-Ariza, T. García-Barrera, J. Vitorica, 2015, Molecular bioSystems.

Inactivating and Noninactivating Components of K+‐Stimulated 45Ca2+ Uptake in Synaptosomes and Variations Due to Aging a

J. Vitorica, J. Satrústegui, E. Bogónez, 1989 .

Galectin‐3 is upregulated in frontotemporal dementia patients with subtype specificity

R. Sánchez-Valle, A. Lladó, A. Antonell, 2023, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Microglia mitochondrial complex I deficiency during development induces glial dysfunction and early lethality.

J. López-Barneo, J. Vitorica, J. Nieto-Gonzalez, 2024, Nature metabolism.