H. Vosberg

发表

Genetic polymorphisms in the renin-angiotensin-aldosterone system associated with expression of left ventricular hypertrophy in hypertrophic cardiomyopathy: a study of five polymorphic genes in a family with a disease causing mutation in the myosin binding protein C gene

F. Ohme, J. Ortlepp, P. Hanrath, 2002, Heart.

The complete sequence of the human beta-myosin heavy chain gene and a comparative analysis of its product.

J. Schleich, P. Lichter, H. Vosberg, 1990, Genomics.

Noncompaction of the Ventricular Myocardium Is Associated with a De Novo Mutation in the β-Myosin Heavy Chain Gene

R. Goody, P. Nürnberg, W. Blankenfeldt, 2007, PloS one.

Mutation and Polymorphism Report

H. Vosberg, C. Rajamanickam, S. Sakthivel, 1999 .

The Promoter of the Human Cardiac β-Myosin Heavy-Chain Gene Is Controlled by an Upstream Enhancer

H. Vosberg, A. Wettstein, 1993 .

The regulation of the human β myosin heavy-chain gene

H. Vosberg, A. Wettstein, U. Horstmann-Herold, 1992 .

Probing Myosin Head Structure with Monoclonal Antibodies and Recombinant Technology

J. Léger, H. Vosberg, D. Mornet, 1991 .

A molecular basis for familial hypertrophic cardiomyopathy: An α β cardiac myosin heavy chain hybrid gene

S. Solomon, J. Seidman, C. Seidman, 1990, Cell.

Enzymatic amplification of myosin heavy-chain mRNA sequences in vitro.

H. Vosberg, P. Harbarth, 1988, DNA.

Regulation of the Human ß-Myosin Heavy Chain Gene and an Approach to a Functional Analysis of Recombinant Protein Subregions of the ß-Chain

J. Léger, H. Vosberg, P. Eldin, 1990 .

The 2373insG mutation in the MYBPC3 gene is a founder mutation, which accounts for nearly one-fourth of the HCM cases in the Netherlands.

V. Regitz-Zagrosek, A. Wilde, F. T. ten Cate, 2003, European heart journal.

A molecular basis for familial hypertrophic cardiomyopathy: an alpha/beta cardiac myosin heavy chain hybrid gene.

S. Solomon, J. Seidman, C. Seidman, 1990, Cell.

Apical hypertrophic cardiomyopathy due to a de novo mutation Arg719Trp of the b-myosin heavy chain gene and cardiac arrest in childhood A case report and family study

T. Meitinger, H. Vosberg, C. Döhlemann, 2000, Zeitschrift für Kardiologie.

A locus for familial hypertrophic cardiomyopathy is closely linked to the cardiac myosin heavy chain genes, CRI-L436, and CRI-L329 on chromosome 14 at q11-q12.

S. Solomon, C. Morton, C. Seidman, 1990, American journal of human genetics.

Instability of short-sequence DNA repeats of pear pathogenic Erwinia strains from Japan and Erwinia amylovora fruit tree and raspberry strains

K. Geider, W.-S. Kim, S. Jock, 2003, Molecular Genetics and Genomics.

Isolation and characterization of the complete human β-myosin heavy chain gene

P. Lichter, T. Ried, H. Vosberg, 1989, Human Genetics.

Characterization of a human genomic DNA fragment coding for a myosin heavy chain

H. Vosberg, H. Appelhans, 2004, Human Genetics.

Expression of human β-myosin heavy chain fragments inEscherichia coli; localization of actin interfaces on cardiac myosin

J. Léger, H. Vosberg, D. Mornet, 1990, Journal of Muscle Research and Cell Motility.

DNA synthesis in nucleotide-permeable Escherichia coli cells. I. Preparation and properties of ether-treated cells.

H. Hoffmann-Berling, H. Vosberg, Hartmut Hoffmann-Berling, 1971, Journal of molecular biology.

Analysis of inherited causes of hypertrophic cardiomyopathy as part of clinical practice

H. Vosberg, P. McKeown, C. Döhlemann, 2000 .

Characterisation of size variants of type I DNA topoisomerase isolated from calf thymus.

H. Vosberg, B. Schmitt, U. Buhre, 1984, European journal of biochemistry.

Inhibition of calf thymus type II DNA topoisomerase by poly(ADP‐ribosylation).

J. Jongstra-Bilen, H. Vosberg, M. K. Darby, 1985, The EMBO journal.

DNA topoisomerase I from calf thymus is inhibited in vitro by poly(ADP-ribosylation).

P. Mandel, J. Jongstra-Bilen, H. Vosberg, 1983, European journal of biochemistry.

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family

D. Fürst, H. Vosberg, M. Wehnert, 2000, Human Genetics.

DNA topoisomerases: enzymes that control DNA conformation.

H. Vosberg, 1985, Current topics in microbiology and immunology.

Purification and demonstration of the enzymatic character of the nicking-closing protein from mouse L cells.

H. Vosberg, J. Vinograd, 1976, Biochemical and biophysical research communications.

Action of nicking-closing enzyme on supercoiled and nonsupercoiled closed circular DNA: formation of a Boltzmann distribution of topological isomers.

H. Vosberg, J. Vinograd, D. Pulleyblank, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Molecular cloning of DNA

H. Vosberg, 1977, Human Genetics.

Isolation and partial characterisation of the relaxation protein from nuclei of cultured mouse and human cells.

L. Grossman, H. Vosberg, J. Vinograd, 1975, European journal of biochemistry.

Carcinogen-induced DNA repair in nucleotide-permeable Escherichia coli cells. Induction of DNA repair by the carcinogens methyl and ethyl nitrosourea and methyl methanesulfonate.

H. Thielmann, H. Vosberg, U. Reygers, 1975, European journal of biochemistry.

Intracellular distribution of DNA topoisomerase I in fibroblasts from patients with Fanconi's anaemia

H. Klocker, M. Schweiger, H. Vosberg, 2004, Human Genetics.

Incorporation of phosphorothioate groups into fd and phi X174 DNA.

H. Vosberg, F. Eckstein, 1977, Biochemistry.

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

J. Seidman, C. Seidman, W. McKenna, 1990, Cell.

The polymerase chain reaction: an improved method for the analysis of nucleic acids

H. Vosberg, 1989, Human Genetics.

Analysis of a dystrophin gene deletion by amplification of mRNA isolated from DMD myotubes cultured in vitro.

E. Schwinger, H. Vosberg, M. Pfordt, 1991, Genomics.

The Use of PCR in the Diagnosis of Muscle Disease

H. Vosberg, M. Pfordt, J. Ehrenpreis, 1991 .

Mapping of the actomyosin interfaces.

M. Le Cunff, J. Léger, H. Vosberg, 1994, Proceedings of the National Academy of Sciences of the United States of America.

α-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere

Christine E. Seidman, Calum MacRae, Ludwig Thierfelder, 1994, Cell.

Cardiac myosin binding protein–C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy

J. Beckmann, J. Weissenbach, M. Komajda, 1995, Nature Genetics.

Genetic analysis in hypertrophic cardiomyopathy : missense mutations in the ventricular myosin regulatory light chain gene

H. Vosberg, A. Mügge, J. Dudenhausen, 2002 .

A newly created splice donor site in exon 25 of the MyBP-C gene is responsible for inherited hypertrophic cardiomyopathy with incomplete disease penetrance.

M. Gautel, W. McKenna, H. Vosberg, 2000, Circulation.

Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene.

J. Seidman, B. Maron, H. Watkins, 1997, Journal of the American College of Cardiology.

Novel deletions in MYH7 and MYBPC3 identified in Indian families with familial hypertrophic cardiomyopathy.

M. Golubenko, K. Schwartz, H. Vosberg, 2003, Journal of molecular and cellular cardiology.

A high risk phenotype of hypertrophic cardiomyopathy associated with a compound genotype of two mutated β-myosin heavy chain genes

T. Meitinger, H. Vosberg, D. Schröder, 1998, Human Genetics.

Partial characterization of the human beta-myosin heavy-chain gene which is expressed in heart and skeletal muscle.

P. Lichter, H. Vosberg, P. K. Umeda, 1986, European journal of biochemistry.

Exclusion of cardiac myosin heavy chain and actin gene involvement in hypertrophic cardiomyopathy of several French families.

J. Beckmann, C. Hengstenberg, F. Fougerousse, 1992, Circulation research.

Chromosomal localization of a human myosin heavy-chain gene by in situ hybridization

G. Rappold, H. Vosberg, 2004, Human Genetics.

Analysis of covalent complexes formed between calf thymus DNA topoisomerase and single-stranded DNA.

H. Vosberg, B. Prell, 1980, European journal of biochemistry.

Scl 70 autoantibodies from scleroderma patients recognize a 95 kDa protein identified as DNA topoisomerase I

E. Penner, H. Vosberg, H. Lakomek, 2004, Chromosoma.

DNA topoisomerase II cleaves at specific sites in the 5′ flanking region of c‐fos proto‐oncogenes in vitro.

A. Nordheim, R. Herrera, H. Vosberg, 1986, The EMBO journal.

Low‐density DNA microarrays are versatile tools to screen for known mutations in hypertrophic cardiomyopathy

H. Vosberg, S. Waldmüller, R. Toder, 2002, Human mutation.

Exclusion ofCardiac MyosinHeavyChainand Actin GeneInvolvement inHypertrophic Cardiomyopathy ofSeveral FrenchFamilies

J. Beckmann, C. Hengstenberg, M. Desnos, 2011 .

Replication of the Single-Stranded DNA of Bacteriophage ϕX174 in Nucleotide-Permeable Cells

H. Hoffmann-Berling, H. Vosberg, O. Schrecker, 1974 .

[Genetic causes of hypertrophic cardiomyopathy].

H. Vosberg, 1998, Medizinische Klinik.

Identification of a mutation near a functional site of the beta cardiac myosin heavy chain gene in a family with hypertrophic cardiomyopathy.

M. Komajda, L. Fetler, P. Guicheney, 1994, Journal of molecular and cellular cardiology.

Genetic counselling for hypertrophic cardiomyopathy: are we ready for it?

H. Vosberg, 2000, Current controlled trials in cardiovascular medicine.

A novel missense mutation (R712L) adjacent to the “active thiol” region of the cardiac β‐myosin heavy chain gene causing hypertrophic cardiomyopathy in an Indian family

H. Vosberg, S. Sakthivel, P. K. Joseph, 2000, Human mutation.

The ubiquitin-proteasome system may be involved in the pathogenesis of hypertrophic cardiomyopathy.

H. Vosberg, 2005, Cardiovascular research.

Relaxation of supercoiled phosphorothioate DNA by mammalian topoisomerases is inhibited in a base-specific manner.

H. Vosberg, M. K. Darby, 1985, The Journal of biological chemistry.

Effect of deoxynucleoside phosphorothioates incorporated in DNA on cleavage by restriction enzymes.

H. Vosberg, F. Eckstein, 1982, The Journal of biological chemistry.

A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.

J. Seidman, A. Bowcock, W. Mckenna, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Direct sequencing of polymerase chain reaction amplified DNA fragments through the incorporation of deoxynucleoside alpha-thiotriphosphates.

G. Gish, H. Vosberg, F. Eckstein, 1988, Nucleic acids research.

Exclusion of cardiac myosin heavy chain and actin gene involvement in hypertrophic cardiomyopathy of several French families.

J. Beckmann, C. Hengstenberg, F. Fougerousse, 1992, Circulation research.