Thomas O'Hara

Cardiac Electrophysiological Substrate Underlying the ECG Phenotype and Electrogram Abnormalities in Brugada Syndrome Patients

Kurt S. Hoffmayer, Y. Rudy, F. Sacher, 2015, Circulation.

Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones.

Thomas O'Hara, Natalia A Trayanova, Fijoy Vadakkumpadan, 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Arrhythmia formation in subclinical ("silent") long QT syndrome requires multiple insults: quantitative mechanistic study using the KCNQ1 mutation Q357R as example.

Thomas O'Hara, Yoram Rudy, Y. Rudy, 2012, Heart rhythm.

Quantitative comparison of cardiac ventricular myocyte electrophysiology and response to drugs in human and nonhuman species.

Thomas O'Hara, Yoram Rudy, Y. Rudy, 2012, American journal of physiology. Heart and circulatory physiology.

Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation.

Y. Rudy, P. Volders, R. Jongbloed, 2008, American journal of physiology. Heart and circulatory physiology.

Degradation of T-Tubular Microdomains and Altered cAMP Compartmentation Lead to Emergence of Arrhythmogenic Triggers in Heart Failure Myocytes: An in silico Study

N. Trayanova, Thomas O'Hara, A. Loucks, 2018, Front. Physiol..

Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure

N. Trayanova, Y. Korchev, J. Gorelik, 2016, Circulation research.

Physiological Properties of hERG 1a/1b Heteromeric Currents and a hERG 1b-Specific Mutation Associated With Long-QT Syndrome

Michael J. Ackerman, Yoram Rudy, Y. Rudy, 2008, Circulation research.

Early somatic mosaicism is a rare cause of long-QT syndrome

Euan A Ashley, Thomas O'Hara, Charles Gawad, 2016, Proceedings of the National Academy of Sciences.

Dysfunction of the Voltage‐Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome

R. Redon, C. Dina, Céline Marionneau, 2016, Journal of the American Heart Association.

Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation

Yoram Rudy, László Virág, Thomas O'Hara, 2011, PLoS Comput. Biol..

Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling.

Thomas O'Hara, Julia Gorelik, Natalia A Trayanova, 2014, Journal of molecular and cellular cardiology.

Complex Brugada syndrome inheritance in a family harbouring compound SCN5A and CACNA1C mutations

R. Redon, D. Pavin, V. Probst, 2014, Basic Research in Cardiology.

Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure

N. Trayanova, Y. Korchev, J. Gorelik, 2016, Circulation research.

Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones.

N. Trayanova, J. Constantino, P. Boyle, 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Physiological Properties of hERG 1a/1b Heteromeric Currents and a hERG 1b-Specific Mutation Associated With Long-QT Syndrome

Y. Rudy, D. Tester, Jiayue He, 2008, Circulation research.

Mutation Associated with Long-qt Syndrome Physiological Properties of Herg 1a/1b Heteromeric Currents and a Herg 1b-specific Physiological Properties of Herg 1a/1b Heteromeric Currents and a Herg 1b-specific Mutation Associated with Long-qt Syndrome Ultrarapid Communication Materials and Methods Cel

Y. Rudy, D. Tester, Jiayue He, 2008 .