Andrew Macdonald

发表

BK virus: Current understanding of pathogenicity and clinical disease in transplantation

M. Reeves, C. Magee, S. Chong, 2019, Reviews in medical virology.

Merkel Cell Polyomavirus Small T Antigen Targets the NEMO Adaptor Protein To Disrupt Inflammatory Signaling

G. Blair, Andrew Macdonald, D. Griffiths, 2013, Journal of Virology.

The cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motility

J. Mankouri, J. Lippiat, G. Blair, 2018, The Journal of Biological Chemistry.

The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors

N. Ranson, M. Frank, Andrew Macdonald, 2018, Structure.

IL-18 and skin inflammation.

M. Wittmann, Andrew Macdonald, J. Renne, 2009, Autoimmunity reviews.

The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-κB by merkel polyomavirus small tumour antigen

J. Arthur, R. Toth, Andrew Macdonald, 2017, Oncotarget.

The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation

J. Scarth, Andrew Macdonald, Ethan L. Morgan, 2021, The Journal of general virology.

MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer

G. Blair, Yigen Li, Andrew Macdonald, 2020, PLoS pathogens.

High-risk human papillomaviruses down-regulate expression of the Ste20 family kinase MST1 to inhibit the Hippo pathway and promote transformation

Andrew Macdonald, Ethan L. Morgan, C. Wasson, 2018, bioRxiv.

Expression of the NS3 protease of cytopathogenic bovine viral diarrhea virus results in the induction of apoptosis but does not block activation of the beta interferon promoter.

J. Mankouri, J. McCauley, Andrew Macdonald, 2010, The Journal of general virology.

Optineurin Negatively Regulates the Induction of IFNβ in Response to RNA Virus Infection

R. Elliott, A. Kohl, J. Mankouri, 2010, PLoS pathogens.

Probing Protein Surfaces: QSAR Analysis with Helix Mimetics

S. Warriner, Andrew J. Wilson, V. Azzarito, 2016, Chembiochem : a European journal of chemical biology.

Norovirus Regulation of the Innate Immune Response and Apoptosis Occurs via the Product of the Alternative Open Reading Frame 4

P. Simmonds, J. Heeney, D. Bailey, 2011, PLoS pathogens.

Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling

J. Mankouri, J. Scarth, Andrew Macdonald, 2022, bioRxiv.

University of Birmingham Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle

Andrew Macdonald, S. Roberts, Ethan L. Morgan, 2017 .

Manipulation of indoleamine 2,3-dioxygenase (IDO) for clinical transplantation: promises and challenges

P. Friend, P. Tan, Andrew Macdonald, 2008 .

Werner Syndrome Protein (WRN) Regulates Cell Proliferation and the Human Papillomavirus 16 Life Cycle during Epithelial Differentiation

D. Das, Andrew Macdonald, Ethan L. Morgan, 2020, mSphere.

Human Papillomavirus E7 Oncoprotein Increases Production of the Anti-Inflammatory Interleukin-18 Binding Protein in Keratinocytes

M. Wittmann, G. Blair, Andrew Macdonald, 2014, Journal of Virology.

Human Papillomavirus E 7 oncoprotein increases 2 production of the anti-inflammatory IL-18 binding 3 protein ( IL-18 BP ) in keratinocytes

Mohammed, M. Wittmann, G. Blair, 2014 .

Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interaction

J. Mankouri, Z. Iglói, A. Kazlauskas, 2015, The Journal of general virology.

Selective and Potent Proteomimetic Inhibitors of Intracellular Protein–Protein Interactions**

Andrew J. Wilson, Kérya Long, T. Edwards, 2015, Angewandte Chemie.

YIP1 family member 4 (YIPF4) is a novel cellular binding partner of the papillomavirus E5 proteins

J. Haas, N. Stonehouse, S. Boxall, 2015, Scientific Reports.

Human papillomavirus E5 oncoprotein: function and potential target for antiviral therapeutics

Andrew Macdonald, E. Prescott, C. Wasson, 2015 .

YIP 1 family member 4 ( YIPF 4 ) is a novel cellular binding partner of the papillomavirus E 5 proteins

J. Haas, N. Stonehouse, S. Boxall, 2015 .

New Structural Insights into the Genome and Minor Capsid Proteins of BK Polyomavirus using Cryo-Electron Microscopy

Andrew Macdonald, Neil A. Ranson, N. Ranson, 2016, Structure.

Alkyl-imino sugars inhibit the pro-oncogenic ion channel function of human papillomavirus (HPV) E5

Andrew Macdonald, D. Kealy, S. Griffin, 2018, Antiviral Research.

High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors

C. Fishwick, G. Blair, N. Stonehouse, 2012, Journal of Virology.

The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer

J. Scarth, Andrew Macdonald, Ethan L. Morgan, 2020, bioRxiv.

STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle

J. Arthur, Joanna L. Parish, N. Coleman, 2018, PLoS pathogens.

Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle

Andrew Macdonald, S. Roberts, Ethan L. Morgan, 2017, Oncotarget.

Human papillomavirus type 18 E 5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle

Andrew Macdonald, S. Roberts, Ethan L. Morgan, 2017 .

Emerging Roles of Viroporins Encoded by DNA Viruses: Novel Targets for Antivirals?

Luis Carrasco, J. L. Nieva, Andrew Macdonald, 2015, Viruses.

The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes

M. Wittmann, G. Blair, Andrew Macdonald, 2015, Scientific Reports.

HPV ) E 5

Andrew Macdonald, D. Kealy, S. Griffin, 2022 .

E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer

J. Scarth, Andrew Macdonald, Ethan L. Morgan, 2020, Cell Death & Differentiation.

Manipulation of JAK/STAT Signalling by High-Risk HPVs: Potential Therapeutic Targets for HPV-Associated Malignancies

Andrew Macdonald, Ethan L. Morgan, A. Macdonald, 2020, Viruses.

Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration

Griffiths Da, G. Blair, Andrew Macdonald, 2014, Journal of Virology.

Introduction of replication-competent hepatitis C virus transcripts using a tetracycline-regulable baculovirus delivery system.

D. Rowlands, Andrew Macdonald, C. McCormick, 2004, The Journal of general virology.

The Hepatitis C Virus NS5A Protein Activates a Phosphoinositide 3-Kinase-dependent Survival Signaling Cascade*

Andrew Macdonald, M. Harris, A. Street, 2004, Journal of Biological Chemistry.

Dysregulation of the miR‐30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication

D. Westhead, Andrew Macdonald, A. Whitehouse, 2022, EMBO reports.

miR-132/212 Knockout Mice Reveal Roles for These miRNAs in Regulating Cortical Synaptic Transmission and Plasticity

J. Reményi, B. Frenguelli, G. Hutvagner, 2013, PloS one.

Glibenclamide inhibits BK polyomavirus infection in kidney cells through CFTR blockade

J. Mankouri, M. Panou, Eleni-Anna Loundras, 2020, Antiviral research.

Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation

J. Mankouri, G. Blair, Andrew Macdonald, 2017, Journal of Virology.

Effect of the Large and Small T-Antigens of Human Polyomaviruses on Signaling Pathways

U. Moens, Andrew Macdonald, A. Macdonald, 2019, International journal of molecular sciences.

Merkel Cell Polyomavirus: Molecular Insights into the Most Recently Discovered Human Tumour Virus

Andrew Macdonald, Hussein K .Abdul-Sada, A. Whitehouse, 2014, Cancers.

JAK2 Inhibition Impairs Proliferation and Sensitises Cervical Cancer Cells to Cisplatin-Induced Cell Death

Andrew Macdonald, Ethan L. Morgan, A. Macdonald, 2019, Cancers.

Hepatitis C Virus NS5A-Mediated Activation of Phosphoinositide 3-Kinase Results in Stabilization of Cellular β-Catenin and Stimulation of β-Catenin-Responsive Transcription

Andrew Macdonald, C. McCormick, M. Harris, 2005, Journal of Virology.

m6A Regulates the Stability of Cellular Transcripts Required for Efficient KSHV Lytic Replication

Stuart A. Wilson, Andrew Macdonald, A. Whitehouse, 2023, bioRxiv.

Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis

Andrew Macdonald, Ethan L. Morgan, A. Macdonald, 2019, PLoS pathogens.

Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness

J. Mankouri, G. Blair, Andrew Macdonald, 2018, PLoS pathogens.

Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility

J. Mankouri, Andrew Macdonald, A. Whitehouse, 2020, The Biochemical journal.

Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence

M. Dallas, J. Mankouri, C. Peers, 2009, Proceedings of the National Academy of Sciences.

High-risk human papillomavirus E 5 oncoprotein displays channel-7 forming activity sensitive to small molecule inhibitors

C. Fishwick, G. Blair, N. Stonehouse, 2012 .

Putting the brakes on the anti-viral response: negative regulators of type I interferon (IFN) production.

Andrew Macdonald, Kathryn H. Richards, A. Macdonald, 2011, Microbes and infection.

The Hepatitis C Virus Non-structural NS5A Protein Inhibits Activating Protein–1 Function by Perturbing Ras-ERK Pathway Signaling*

K. Saksela, Andrew Macdonald, C. McCormick, 2003, The Journal of Biological Chemistry.

Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

J. Arthur, D. Campbell, R. Toth, 2006, BMC Cell Biology.

Quantitative Proteomics Using Stable Isotope Labeling with Amino Acids in Cell Culture Reveals Changes in the Cytoplasmic, Nuclear, and Nucleolar Proteomes in Vero Cells Infected with the Coronavirus Infectious Bronchitis Virus*

J. Hiscox, E. Emmott, Andrew Macdonald, 2010, Molecular & Cellular Proteomics.

Hepatitis C virus NS5A: tales of a promiscuous protein.

Mark Harris, Andrew Macdonald, Andrew Macdonald, 2004, The Journal of general virology.

Identification of TRIM23 as a Cofactor Involved in the Regulation of NF-κB by Human Cytomegalovirus

A. Alcamí, J. Sinclair, Andrew Macdonald, 2009, Journal of Virology.

MSK regulate TCR‐induced CREB phosphorylation but not immediate early gene transcription

J. Arthur, Andrew Macdonald, Giselle R. Wiggin, 2007, European journal of immunology.

Defining the frequency of human papillomavirus and polyomavirus infection in urothelial bladder tumours

M. Zeegers, N. James, D. Ward, 2018, Scientific Reports.

Characterization of the cellular action of the MSK inhibitor SB-747651A.

Andrew Macdonald, A. Reith, J. Arthur, 2012, The Biochemical journal.

Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection

N. Ranson, M. Hollinshead, M. Panou, 2018, International journal of molecular sciences.

CircHIPK3 dysregulation of the miR-30c/DLL4 axis is essential for KSHV lytic replication

D. Westhead, Andrew Macdonald, A. Whitehouse, 2021, bioRxiv.

Inhibitors of the Small Membrane (M) Protein Viroporin Prevent Zika Virus Infection

N. Ranson, A. Kohl, Rebecca F. Thompson, 2021, bioRxiv.

Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer

Simak Ali, M. Periyasamy, T. Fenton, 2022, Oncogene.

BK polyomavirus (BKPyV) is a risk factor for bladder cancer through induction of APOBEC3-mediated genomic damage

Simak Ali, M. Periyasamy, T. Fenton, 2021, bioRxiv.

Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Akt - NFκB - IL-6 signalling axis

Andrew Macdonald, Ethan L. Morgan, A. Macdonald, 2018 .

Selective and Potent Proteomimetic Inhibitors of Intracellular Protein–Protein Interactions†

Andrew J. Wilson, Kérya Long, T. Edwards, 2015, Angewandte Chemie.

Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS.

J. Arthur, D. Campbell, J. Simon, 2007, The Biochemical journal.

Defining the frequency of human papillomavirus and polyomavirus infection in urothelial bladder tumours

M. Zeegers, N. James, D. Ward, 2018, Scientific Reports.

ERK5 regulation in naïve T‐cell activation and survival

J. Arthur, C. Tournier, Andrew Macdonald, 2008, European Journal of Immunology.

Perturbation of epidermal growth factor receptor complex formation and Ras signalling in cells harbouring the hepatitis C virus subgenomic replicon.

Mark Harris, Andrew Macdonald, Andrew Macdonald, 2005, The Journal of general virology.

Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy

Monoj Mon Kalita, C. Scott, A. Tarr, 2018, bioRxiv.

Agnoprotein is an essential egress factor during BK 3 polyomavirus infection 4 5 6

Louisa, N. Ranson, M. Hollinshead, 2018 .

Different NF-κB activation characteristics of human respiratory syncytial virus subgroups A and B.

J. Barr, J. Hiscox, Andrew Macdonald, 2012, Microbial pathogenesis.

The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity.

Andrew Macdonald, C. McCormick, M. Harris, 2004, The Journal of general virology.