H. Voshol

发表

Evaluation of biomarker discovery approaches to detect protein biomarkers of acute renal allograft rejection.

R. Morris, G. Wieczorek, J. van Oostrum, 2005, Journal of proteome research.

The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity

W. Sellers, A. Bauer, Christopher J. Wilson, 2013, PloS one.

Identification of Apolipoprotein A-I as a “STOP” Signal for Myopia*

F. Schaeffel, K. Schmid, J. van Oostrum, 2006, Molecular & Cellular Proteomics.

Antibody‐based proteomics

Markus Ehrat, Hans Voshol, J. van Oostrum, 2009, The FEBS journal.

Proteomics in pharmaceutical research and development

P. Cutler, H. Voshol, 2015, Proteomics. Clinical applications.

Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

K. Cornille, D. Bonenfant, M. Bentires-Alj, 2016, Breast Cancer Research.

The structural basis of Indisulam-mediated recruitment of RBM39 to the DCAF15-DDB1-DDA1 E3 ligase complex

V. Hornak, D. Bussiere, C. Wiesmann, 2019, bioRxiv.

Scalable Production in Human Cells and Biochemical Characterization of Full-Length Normal and Mutant Huntingtin

B. Gerrits, S. Kochanek, J. Buchner, 2015, PLoS ONE.

3.02 – Proteomics

H. Voshol, 2007 .

Triggering the succinate receptor GPR91 on dendritic cells enhances immunity

T. Junt, A. Rot, Julian Kund, 2008, Nature Immunology.

Mammary tumor formation and metastasis evoked by a HER2 splice variant.

N. Aceto, D. Bonenfant, M. Bentires-Alj, 2013, Cancer research.

Cell surface glycoconjugates as possible target structures for human natural killer cells: evidence against the involvement of glycolipids and N-linked carbohydrate chains.

J. Vliegenthart, H. Voshol, H. Dullens, 1993, Glycobiology.

Fluoroaluminate stimulates phosphorylation of p130 Cas and Fak and increases attachment and spreading of preosteoblastic MC3T3-E1 cells.

M. Šuša, J. van Oostrum, H. Voshol, 2002, Bone.

HB4 antibody recognizes a carbohydrate structure on lymphocyte surface proteins related to HB6, CDw75, and CD76 antigens.

W. de Lau, H. Clevers, J. Kuipers, 1993, Journal of immunology.

Identification of the human melanoma-associated chondroitin sulfate proteoglycan antigen epitope recognized by the antitumor monoclonal antibody 763.74 from a peptide phage library.

M. Geiser, C. García-echeverría, H. Voshol, 1999, Cancer research.

Analysis of N-acetyl-4-O-acetylneuraminic-acid-containing N-linked carbohydrate chains released by peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase F. Application to the structure determination of the carbohydrate chains of equine fibrinogen.

K. Hård, J. Kamerling, J. Vliegenthart, 1989, European journal of biochemistry.

Evaluation of biomarker discovery approaches to detect protein biomarkers of acute renal allograft rejection.

R. Morris, G. Wieczorek, J. van Oostrum, 2005, Journal of proteome research.

Theβ-subunit of human chorionic gonadotropin containsN-glycosidic trisialo tri- and tri′-antennary carbohydrate chains

K. Hård, J. Kamerling, J. Vliegenthart, 1988, Glycoconjugate Journal.

Different isoforms of an apoprotein (apolipophorin III) associate with lipoproteins in Locusta migratoria.

M. Kanost, H. Voshol, D. J. Van der Horst, 1991, European journal of biochemistry.

Structure of the HNK-1 Carbohydrate Epitope on Bovine Peripheral Myelin Glycoprotein P0*

M. Schachner, J. Vliegenthart, H. Voshol, 1996, The Journal of Biological Chemistry.

Inhibition of Dengue Virus Polymerase by Blocking of the RNA Tunnel

P. Niyomrattanakit, Yen-Liang Chen, P. Shi, 2010, Journal of Virology.

Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex

V. Hornak, D. Bussiere, C. Wiesmann, 2019, Nature Chemical Biology.

Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent.

W. Sellers, R. Levine, F. Hofmann, 2012, Cancer discovery.

The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα

Michael B. Stadler, G. Bonamy, A. Orth, 2017, Nature.

Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition.

W. Sellers, E. Billy, C. Schnell, 2016, Cancer research.

Neuroproteomics: Expression Profiling of the Brain's Proteomes in Health and Disease

Michael Cascio, Hans Voshol, M. Cascio, 2004, Neurochemical Research.

Integrative Proteogenomics for Differential Expression and Splicing Variation in a DM1 Mouse Model

S. Hoersch, U. Naumann, J. Fessenden, 2021, bioRxiv.

Proteomics-based Target Identification

Sunkyu Kim, Hans Voshol, J. Decaprio, 2003, Journal of Biological Chemistry.

Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases

Michael B. Stadler, N. Aceto, J. Wyckoff, 2014, Oncogene.

Human natural killer cells: a convenient purification procedure and the influence of cryopreservation on cytotoxic activity.

J. Vliegenthart, H. Voshol, H. Dullens, 1993, Journal of immunological methods.

Identification of a peptide mimic of the L2/HNK‐1 carbohydrate epitope

M. Schachner, N. Mantei, H. Voshol, 2002, Journal of neurochemistry.

Antibody-based arrays in disease proteomics

H. Voshol, Daniel A Guthy, 2015 .

Towards high performance two‐dimensional gel electrophoresis using ultrazoom gels

S. Hoving, J. van Oostrum, H. Voshol, 2000, Electrophoresis.

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency

Jeffrey A. Porter, R. Dolmetsch, T. Bouwmeester, 2016, Science.

From proteomics to systems biology of bacterial pathogens: Approaches, tools, and applications

Manuel C Peitsch, Uwe Plikat, Jan van Oostrum, 2007, Proteomics.

N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase.

P. Niyomrattanakit, Yen-Liang Chen, P. Shi, 2009, Journal of medicinal chemistry.

ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer

D. Bonenfant, U. Duvvuri, Anke Bill, 2015, Oncotarget.

Epitope Diversity of N-Glycans from Bovine Peripheral Myelin Glycoprotein P0 Revealed by Mass Spectrometry and Nano Probe Magic Angle Spinning 1H NMR Spectroscopy*

M. Schachner, J. Blanco, J. Duus, 2001, The Journal of Biological Chemistry.

Reduced Susceptibility of Haemophilus influenzae to the Peptide Deformylase Inhibitor LBM415 Can Result from Target Protein Overexpression Due to Amplified Chromosomal def Gene Copy Number

D. Daigle, J. Leeds, J. Koehn, 2007, Antimicrobial Agents and Chemotherapy.

Isotope-tagged cross-linking reagents. A new tool in mass spectrometric protein interaction analysis.

M. Steinmetz, S. Hoving, H. Towbin, 2001, Analytical chemistry.

Preparative two‐dimensional gel electrophoresis at alkaline pH using narrow range immobilized pH gradients

B. Gerrits, R. Roberts, S. Hoving, 2002, Proteomics.

Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C

N. Ostermann, C. Schnell, Toshio Shimizu, 2022, Cancer discovery.

Tracing pathway activities with kinase inhibitors and reverse phase protein arrays

Doriano Fabbro, Markus Ehrat, Hans Voshol, 2009, Proteomics. Clinical applications.

Proteomics: From Protein Identification to Biological function

S. Hoving, H. Towbin, H. Voshol, 2001, CHIMIA.

CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

M. Mclaughlin, D. Bonenfant, M. Bentires-Alj, 2015, Oncogene.

The role of lysine palmitoylation/myristoylation in the function of the TEAD transcription factors

D. Erdmann, M. Affolter, P. Chène, 2022, Scientific Reports.

LC-MALDI MS and MS/MS--an efficient tool in proteome analysis.

Annick Waldt, J. van Oostrum, H. Voshol, 2007, Sub-cellular biochemistry.

Mass spectrometric characterization of stathmin isoforms separated by 2D PAGE.

J. van Oostrum, H. Voshol, P. Schindler, 1999, Journal of mass spectrometry : JMS.

Proteomics in the discovery of new therapeutic targets for psychiatric disease.

M. Glucksman, J. van Oostrum, H. Voshol, 2003, Current molecular medicine.

JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid Tumors.

N. Ostermann, R. Wilcken, S. Brachmann, 2022, Journal of medicinal chemistry.

Guidelines for reporting the use of gel electrophoresis in proteomics

Chris F. Taylor, Joachim Klose, Gyorgy Babnigg, 2008, Nature Biotechnology.

Phosphorylation disrupts the central helix in Op18/stathmin and suppresses binding to tubulin

W. Jahnke, M. Steinmetz, C. García-echeverría, 2001, EMBO reports.

Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases

Michael B. Stadler, N. Aceto, J. Wyckoff, 2014, Oncogene.

Mammary tumor formation and metastasis evoked by a HER2 splice variant.

N. Aceto, D. Bonenfant, M. Bentires-Alj, 2013, Cancer research.