D. Cohen

发表

Triglyceride Metabolism in the Liver.

M. Alves-Bezerra, D. Cohen, D. Cohen, 2017, Comprehensive Physiology.

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

Y. Kawano, D. Cohen, D. Cohen, 2013, Journal of Gastroenterology.

Structure of human phosphatidylcholine transfer protein in complex with its ligand

M. Vetting, K. Rajashankar, Diana S. Agate, 2002, Nature Structural Biology.

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

T. Shioda, R. Gerszten, A. Näär, 2010, Science.

Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice

Richard T. Lee, Katherine B. LeClair, Alexander S. Banks, 2020, Scientific Reports.

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

John M. Asara, Wolfram Goessling, David E. Cohen, 2016, Nature Cell Biology.

Knockout of the X‐linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity

D. Cohen, G. Pitt, Aravind R. Gade, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

CXCR3 Controls T-Cell Accumulation in Fat Inflammation

P. Libby, M. Bittencourt, T. Christen, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Submicellar bile salts stimulate phosphatidylcholine transfer activity of sterol carrier protein 2.

D. Cohen, A. Léonard, Andrew N. Leonard, 1998, Journal of lipid research.

Of TICE in Men.

D. Cohen, 2016, Cell metabolism.

Balancing cholesterol synthesis and absorption in the gastrointestinal tract.

D. Cohen, D. Cohen, 2008, Journal of clinical lipidology.

Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mices⃞s⃞ The online version of this article (available at http://www.jlr.org) contains an additional table. Published, JLR Papers in Press, December 1, 2004. DOI 10.1194/jlr.M400387-JL

P. Novikoff, S. Yadav, D. Cohen, 2005, Journal of Lipid Research.

Hepatic Overexpression of Murine Abcb11 Increases Hepatobiliary Lipid Secretion and Reduces Hepatic Steatosis*

F. Lammert, R. Korstanje, S. Matern, 2004, Journal of Biological Chemistry.

Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse.

S. Tazuma, D. Cohen, M. Carey, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Hepatic overexpression of sterol carrier protein-2 inhibits VLDL production and reciprocally enhances biliary lipid secretion Published, JLR Papers in Press, November 4, 2002. DOI 10.1194/jlr.M200306-JLR200

A. Rigotti, J. Miquel, F. Nervi, 2003, Journal of Lipid Research.

Thioesterase Superfamily Member 2 (Them2) and Phosphatidylcholine Transfer Protein (PC-TP) Interact To Promote Fatty Acid Oxidation and Control Glucose Utilization

Y. Kawano, S. Nishiumi, Masaru Yoshida, 2014, Molecular and Cellular Biology.

PC-TP/StARD2: Of membranes and metabolism

D. Cohen, H. Kang, Jie Wei, 2010, Trends in Endocrinology & Metabolism.

Thioesterase superfamily member 1 suppresses cold thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids in brown adipose tissue

Katherine B. LeClair, Alexander S. Banks, R. Betensky, 2016, Molecular metabolism.

Hepatocellular transport and secretion of biliary lipids.

D. Cohen, D. Cohen, David E. Cohen, 1999, Current opinion in lipidology.

ASMBS Guidelines/Statements, Part 2 Lipids and bariatric procedures Part 2 of 2: scientific statement from the American Society for Metabolic and Bariatric Surgery (ASMBS), the National Lipid Association (NLA), and Obesity Medicine Association (OMA) 1

D. Azagury, N. Nguyen, S. Kothari, 2016 .

Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins.

Y. Marcel, M. Lisanti, F. Galbiati, 2001, American journal of physiology. Cell physiology.

Allosteric regulation of Thioesterase Superfamily Member 1 by free fatty acids and lysophosphatidylcholine

E. Ortlund, C. Okafor, Puneet Juneja, 2020, bioRxiv.

Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress

D. Cohen, Yingxia Li, Baran A Ersoy, 2017, The Journal of clinical investigation.

Bile acid regulation of hepatic physiology: I. Hepatocyte transport of bile acids.

A. Wolkoff, D. Cohen, D. Cohen, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Microvascular Hyperpermeability in Caveolin-1 (−/−) Knock-out Mice

S. Woodman, M. Lisanti, C. Chow, 2002, The Journal of Biological Chemistry.

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes.

L. Zon, W. Goessling, Y. Houvras, 2019, Gastroenterology.

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins.

C. Kahn, B. Gibson, J. Meyer, 2019, Cell metabolism.

Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice

M. Pittman, C. Rice, H. Suemizu, 2020, bioRxiv.

Suppression of Fatty Acid Oxidation by Thioesterase Superfamily Member 2 in Skeletal Muscle Promotes Hepatic Steatosis and Insulin Resistance

E. Ortlund, M. Alves-Bezerra, D. Cohen, 2021, bioRxiv.

An assessment of statin safety by hepatologists.

N. Chalasani, F. Anania, D. Cohen, 2006, The American journal of cardiology.

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.

C. Kahn, T. N. Rao, O. Ilkayeva, 2018, The Journal of clinical investigation.

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

C. Kahn, T. N. Rao, O. Ilkayeva, 2017, The Journal of clinical investigation.

Structural alterations in lecithin-cholesterol vesicles following interactions with monomeric and micellar bile salts: physical-chemical basis for subselection of biliary lecithin species and aggregative states of biliary lipids during bile formation.

D. Cohen, M. Carey, M. Angelico, 1990, Journal of lipid research.

In vitro evidence that phospholipid secretion into bile may be coordinated intracellularly by the combined actions of bile salts and the specific phosphatidylcholine transfer protein of liver.

D. Cohen, M. Carey, M. R. Leonard, 1994, Biochemistry.

Thioesterase Superfamily Member 2/Acyl-CoA Thioesterase 13 (Them2/Acot13) Regulates Adaptive Thermogenesis in Mice*

Katherine B. LeClair, C. Kahn, Y. Kawano, 2013, The Journal of Biological Chemistry.

Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance

P. Larsen, Y. Kawano, D. Cohen, 2012, Proceedings of the National Academy of Sciences.

Regulation of Lipid and Glucose Metabolism by Phosphatidylcholine Transfer Protein

D. Cohen, H. Kang, J. Wei, 2010 .

Up‐regulation of thioesterase superfamily member 2 in skeletal muscle promotes hepatic steatosis and insulin resistance in mice

E. Ortlund, M. Alves-Bezerra, D. Cohen, 2021, Hepatology.

Restoration of gallstone susceptibility by leptin in C57BL/6J ob/ob mice Published, JLR Papers in Press, April 1, 2003. DOI 10.1194/jlr.M300029-JLR200

Suheeta Roy, D. Cohen, H. Hyogo, 2003, Journal of Lipid Research.

Cholesterol gallstones

S. Tazuma, D. Cohen, H. Hyogo, 2002, Current opinion in gastroenterology.

Targeted Deletion of Fibrinogen Like Protein 1 Reveals a Novel Role in Energy Substrate Utilization

C. Ukomadu, D. Cohen, Yingxia Li, 2013, PloS one.

A human liver chimeric mouse model for non-alcoholic fatty liver disease

Pavel Sumazin, N. McKenna, D. Moore, 2021, JHEP reports : innovation in hepatology.

From NAFLD to MAFLD: Implications of a Premature Change in Terminology

Z. Goodman, A. Sanyal, Z. Younossi, 2020, Hepatology.

Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet‐induced hepatic glucose production

M. Glicksman, G. Cuny, D. Cohen, 2011, Hepatology.

Trimming the Fat: Acetyl‐CoA Carboxylase Inhibition for the Management of NAFLD

D. Cohen, Norihiro Imai, D. Cohen, 2018, Hepatology.

Blocking ActRIIB signaling and restoring appetite reverses cachexia and improves survival in mice with lung cancer

Marcus D. Goncalves, L. Cantley, J. Kirwan, 2021 .

Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice

S. Kersten, Ann-Hwee Lee, D. Cohen, 2021, The Journal of biological chemistry.

iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy.

Katherine B. LeClair, Alexander S. Banks, D. Drucker, 2016, Cell metabolism.

iNKT Cells Induce FGF 21 f or Thermogenesis and Are Required for Maximal Weight Loss in GLP 1 Therapy Graphical

Katherine B. LeClair, Alexander S. Banks, D. Drucker, 2016 .

Phosphatidylcholine Transfer Protein Interacts with Thioesterase Superfamily Member 2 to Attenuate Insulin Signaling

M. White, B. Manning, C. Ukomadu, 2013, Science Signaling.

Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice Published, JLR Papers in Press, February 16, 2003. DOI 10.1194/jlr.M200489-JLR200

M. Ananthanarayanan, D. Cohen, N. Balasubramaniyan, 2003, Journal of Lipid Research.

Decreased lipid efflux and increased susceptibility to cholesterol-induced apoptosis in macrophages lacking phosphatidylcholine transfer protein.

I. Tabas, D. Cohen, J. M. Báez, 2005, The Biochemical journal.

Phosphatidylcholine Transfer Protein Promotes Apolipoprotein A-I-mediated Lipid Efflux in Chinese Hamster Ovary Cells*

D. Cohen, S. Barbour, J. M. Báez, 2002, The Journal of Biological Chemistry.

Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPARα-mediated redistribution of ABCB4 Published, JLR Papers in Press, July 16, 2004. DOI 10.1194/jlr.M400132-JLR200

Y. Sugiyama, N. Tanaka, Hiroshi Suzuki, 2004, Journal of Lipid Research.

Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPARalpha-mediated redistribution of ABCB4.

Y. Sugiyama, N. Tanaka, Hiroshi Suzuki, 2004, Journal of lipid research.

Filamentous Crystallization of Cholesterol and Its Dependence on Lecithin Species in Bile

D. Cohen, M. Carey, F. Konikoff, 1994 .

Acyl chain unsaturation modulates distribution of lecithin molecular species between mixed micelles and vesicles in model bile. Implications for particle structure and metastable cholesterol solubilities.

D. Cohen, M. Carey, D. Cohen, 1991, Journal of lipid research.

Cloning and gene structure of rat phosphatidylcholine transfer protein, Pctp.

D. Cohen, Michele K. Wu, M. Wu, 1999, Gene.

The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis

Feng Li, Hongliang Li, P. Zhang, 2018, Nature Medicine.

Preemptive Activation of the Integrated Stress Response Protects Mice From Diet‐Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction

J. Gromada, Ann-Hwee Lee, D. Cohen, 2018, Hepatology.

Decreased Expression of ARV1 Results in Cholesterol Retention in the Endoplasmic Reticulum and Abnormal Bile Acid Metabolism*

Y. Liu, D. Rader, M. Graham, 2010, The Journal of Biological Chemistry.

STARTing to understand MLN64 function in cholesterol transport1

A. Rigotti, D. Cohen, S. Zanlungo, 2010, Journal of Lipid Research.

Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway.

R. H. Costa-e-Sousa, A. Hollenberg, D. Cohen, 2014, The Journal of clinical investigation.

Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse.

A. Rigotti, F. Nervi, D. Cohen, 2007, Biochimica et biophysica acta.

Hepatocellular Transport and Secretion of Biliary Phospholipids

D. Cohen, David E. Cohen, 1996, Seminars in liver disease.

Bile salt hydrophobicity controls vesicle secretion rates and transformations in native bile.

D. Cohen, M. Carey, L. S. Leighton, 1992, The American journal of physiology.

Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis.

F. Lammert, B. Paigen, D. Cohen, 1999, The American journal of physiology.

Immobilized artificial membrane chromatography: a rapid and accurate HPLC method for predicting bile salt-membrane interactions.

D. Cohen, M. Leonard, M. R. Leonard, 1995, Journal of lipid research.

Homozygous disruption of Pctp modulates atherosclerosis in apolipoprotein E-deficient mice Published, JLR Papers in Press, August 28, 2006.

D. Cohen, R. Maurer, H. Dansky, 2006, Journal of Lipid Research.

Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis.

F. Lammert, B. Paigen, D. Cohen, 1999, American journal of physiology. Gastrointestinal and liver physiology.

Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis

Pardis C Sabeti, N. Shah, E. Schadt, 2015, Nature Medicine.

Disruption of Thyroid Hormone Activation in Type 2 Deiodinase Knockout Mice Causes Obesity With Glucose Intolerance and Liver Steatosis Only at Thermoneutrality

J. Hall, A. Bianco, D. Cohen, 2011, Diabetes.

Lipoprotein Metabolism, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

E. Fisher, D. Cohen, D. Cohen, 2013, Seminars in Liver Disease.

Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer

L. Cantley, J. Kirwan, Zhidan Wu, 2022, Nature Communications.

Association between liver fibrosis and cognition in a nationally representative sample of older adults

H. Kamel, C. Iadecola, D. Cohen, 2020, European journal of neurology.

Lipoprotein Metabolism and Cholesterol Balance

D. Cohen, D. Cohen, 2009, The Liver.

Etiologic significance of defects in cholesterol, phospholipid, and bile acid metabolism in the liver of patients with intrahepatic calculi

Y. Sugiyama, Y. Nimura, N. Tanaka, 2001, Hepatology.

Phosphatidylcholine transfer protein/StarD2 promotes microvesicular steatosis and liver injury in murine experimental steatohepatitis.

J. Hornick, D. Cohen, H. T. Nicholls, 2017, American journal of physiology. Gastrointestinal and liver physiology.

Thioesterase superfamily member 2/acyl‐CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism

Y. Kawano, D. Cohen, Shuxin Han, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

High incidence of cholesterol gallstone disease in type 1 Gaucher disease: characterizing the biliary phenotype of type 1 Gaucher disease

J. Dziura, Shu Chen, T. Taddei, 2010, Journal of Inherited Metabolic Disease.

Leptin Promotes Biliary Cholesterol Elimination during Weight Loss in ob/ob Mice by Regulating the Enterohepatic Circulation of Bile Salts*

B. Paigen, Suheeta Roy, D. Cohen, 2002, The Journal of Biological Chemistry.

Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice.

Amanda J. Pickard, E. Pamer, R. Jenq, 2018, Cell host & microbe.

Regulation of fatty acid trafficking in liver by thioesterase superfamily member 1[S]

M. Alves-Bezerra, D. Cohen, Yingxia Li, 2017, Journal of Lipid Research.

Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis

E. Ortlund, M. Alves-Bezerra, D. Cohen, 2018, Hepatology.

Genetic ablation of phosphatidylcholine transfer protein/StarD2 in ob/ob mice improves glucose tolerance without increasing energy expenditure.

Katherine B. LeClair, T. Krisko, D. Cohen, 2017, Metabolism: clinical and experimental.

Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine

E. Ortlund, C. Okafor, Puneet Juneja, 2020, Proceedings of the National Academy of Sciences.

Biochemical characterization of L-DOPA 2,3-dioxygenase, a single-domain type I extradiol dioxygenase from lincomycin biosynthesis.

Jennifer Rosenberg, K. Colabroy, D. Cohen, 2008, Archives of biochemistry and biophysics.

Intracerebroventricular leptin regulates hepatic cholesterol metabolism.

L. Rossetti, G. Karkanias, D. Cohen, 2004, The Biochemical journal.

Mice overexpressing hepatic Abcb11 rapidly develop cholesterol gallstones

R. Green, D. Cohen, A. Henkel, 2005, Mammalian Genome.

Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: FULL REPORT.

D. Azagury, N. Nguyen, S. Kothari, 2016, Journal of clinical lipidology.

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

C. Kahn, S. Softic, D. Cohen, 2016, Digestive Diseases and Sciences.

The 2020 Nobel Prize for Medicine or Physiology for the Discovery of Hepatitis C Virus: A Triumph of Curiosity and Persistence

A. Lok, J. Hoofnagle, T. Liang, 2021, Hepatology.

Liver histology during Mipomersen therapy for severe hypercholesterolemia.

R. Odze, R. Santos, E. Stroes, 2014, Journal of clinical lipidology.

No pathophysiologic relationship of soluble biliary proteins to cholesterol crystallization in human bile.

F. Lammert, D. Cohen, M. Carey, 1999, Journal of lipid research.

Phosphatidylcholine transfer protein regulates size and hepatic uptake of high-density lipoproteins.

D. Cohen, Michele K. Wu, D. Cohen, 2005, American journal of physiology. Gastrointestinal and liver physiology.

Phospholipid molecular species influence crystal habits and transition sequences of metastable intermediates during cholesterol crystallization from bile salt-rich model bile.

D. Cohen, M. Carey, F. Konikoff, 1994, Journal of lipid research.

Laser light scattering evidence for a common wormlike growth structure of mixed micelles in bile salt- and straight-chain detergent-phosphatidylcholine aqueous systems: relevance to the micellar structure of bile.

G. Benedek, D. Cohen, M. Carey, 1998, Biochemistry.

Human phosphatidylcholine transfer protein: purification, crystallization and preliminary X-ray diffraction data.

D. Cohen, S. Roderick, W. W. Chan, 2002, Biochimica et biophysica acta.

Rapid (1 hour) high performance gel filtration chromatography resolves coexisting simple micelles, mixed micelles, and vesicles in bile.

D. Cohen, M. Carey, M C Carey, 1990, Journal of lipid research.

Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID‐19 Pandemic: AASLD Expert Panel Consensus Statement

R. Fontana, K. Reddy, R. Chung, 2020, Hepatology.

Evidence for an ATP-independent long-chain phosphatidylcholine translocator in hepatocyte membranes.

D. Cohen, M. Carey, M. Fuchs, 1997, American journal of physiology. Gastrointestinal and liver physiology.

Evidence for an ATP-independent long-chain phosphatidylcholine translocator in hepatocyte membranes.

D. Cohen, M. Carey, M. Fuchs, 1997, The American journal of physiology.

Functional characterization of thioesterase superfamily member 1/Acyl-CoA thioesterase 11: implications for metabolic regulation[S]

D. Cohen, Shuxin Han, 2012, Journal of Lipid Research.

Structure and Function of Phosphatidylcholine Transfer Protein (pc-tp)/stard2

D. Cohen, S. Roderick, Michele K. Wu, 2022 .

Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein.

D. Beier, R. Green, D. Cohen, 1999, Biochimica et biophysica acta.

Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice.

A. Rigotti, M. Krieger, J. Miquel, 2001, Journal of lipid research.

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling

Richard T. Lee, Katherine B. LeClair, P. Patwari, 2017, PloS one.

Interacting Proteins Dictate Function of the Minimal START Domain Phosphatidylcholine Transfer Protein/StarD2*

C. Ukomadu, N. Wagle, Diana S. Agate, 2007, Journal of Biological Chemistry.

Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice.

Alexander S. Banks, T. Krisko, G. Putzel, 2020, Cell metabolism.

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

C. Kahn, J. Plutzky, D. Cohen, 2012, Nature Medicine.

The arrestin domain-containing 3 protein regulates body mass and energy expenditure.

Richard T. Lee, Radu Dobrin, E. Schadt, 2011, Cell metabolism.

Sensitivity of Lipid Metabolism and Insulin Signaling to Genetic Alterations in Hepatic Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Expression

B. Spiegelman, G. Shulman, D. Cohen, 2009, Diabetes.

Sensitivity of Lipid Metabolism and Insulin Signaling to Genetic Alterations in Hepatic Peroxisome Proliferator–Activated Receptor-\(\gamma\) Coactivator-1\(\alpha\) Expression

B. Spiegelman, G. Shulman, D. Cohen, 2009 .

Rationale and design of a prospective clinical trial program to evaluate the glucose-lowering effects of colesevelam HCl in patients with type 2 diabetes mellitus

H. Bays, D. Cohen, D. Cohen, 2007, Current medical research and opinion.

CalR: A Web-based Analysis Tool for Indirect Calorimetry Experiments

Amir I Mina, Raymond A LeClair, Katherine B LeClair, 2017, bioRxiv.

Deactivating Fatty Acids: Acyl-CoA Thioesterase-Mediated Control of Lipid Metabolism

D. Cohen, S. Alexson, Veronika Tillander, 2017, Trends in Endocrinology & Metabolism.

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

L. Glimcher, Ann-Hwee Lee, D. Cohen, 2008, Science.

Maternal Programming of Social Dominance via Milk Cytokines

M. Toth, M. V. D. van den Brink, M. Alves-Bezerra, 2020, iScience.

Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue

Amir I. Mina, Katherine B. LeClair, Alexander S. Banks, 2017, Molecular metabolism.

The gene encoding the multispecific organic anion transporter (Cmoat) of the hepatocyte canalicular membrane maps to mouse Chromosome 19

F. Lammert, D. Beier, B. Paigen, 2009, Mammalian Genome.

An assessment by the Statin Liver Safety Task Force: 2014 update.

N. Chalasani, H. Bays, D. Cohen, 2014, Journal of clinical lipidology.

CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients

E. Schiff, D. Shapiro, L. Macconell, 2019, Liver international : official journal of the International Association for the Study of the Liver.

Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance.

L. Rossetti, D. Cohen, S. VanPatten, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Physical chemistry of biliary lipids during bile formation.

D. Cohen, M. Carey, 1990, Hepatology.

Brain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma.

S. Waisbren, A. O’Donnell-Luria, B. Levy, 2017, Molecular genetics and metabolism.

Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2

A. Pocai, L. Rossetti, S. Biddinger, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.

G. Stephanopoulos, C. Kahn, G. King, 2008, Cell metabolism.

Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat.

D. Cohen, M. Vore, C. R. Wooton-Kee, 2008, American journal of physiology. Gastrointestinal and liver physiology.

of the bile acid pool in the lactating rat-hydroxylase expression and size α Increased cholesterol 7

D. Cohen, M. Vore, R. Wooton-Kee, 2008 .

Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice

Richard T. Lee, Katherine B. LeClair, Alexander S. Banks, 2020, Scientific Reports.

Attenuated Effects of Bile Acids on Glucose Metabolism and Insulin Sensitivity in a Male Mouse Model of Prenatal Undernutrition

M. Patti, J. Gordon, W. Gall, 2017, Endocrinology.

D. Azagury, N. Nguyen, S. Kothari, 2016, Journal of clinical lipidology.

Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs.

D. Cohen, H. Kang, Jie Wei, 2009, The Biochemical journal.

Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity.

A. Choi, M. Plataki, D. Cohen, 2019, JCI insight.

High-level expression and mutagenesis of recombinant human phosphatidylcholine transfer protein using a synthetic gene: evidence for a C-terminal membrane binding domain.

D. Cohen, S. Roderick, W. W. Chan, 2000, Biochemistry.

Food-associated stimuli enhance barrier properties of gastrointestinal mucus.

Lauren Speciner, R. Carrier, D. Cohen, 2015, Biomaterials.

Quasielastic light scattering evidence for vesicular secretion of biliary lipids.

D. Cohen, M. Carey, M. Angelico, 1989, The American journal of physiology.

Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARalpha).

D. Cohen, H. Kang, E. Scapa, 2010, Biochimica et biophysica acta.

Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP

D. Forrest, A. Lyubetskaya, D. Tenen, 2021, Science Signaling.

Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1–induced steatosis

R. Coleman, M. Alves-Bezerra, D. Cohen, 2018, The Journal of Biological Chemistry.

New players on the metabolic stage

D. Cohen, D. Cohen, 2013, Adipocyte.

CalR: A Web-based Analysis Tool for Indirect Calorimetry Experiments

Louise Lantier, David E. Cohen, Amir I. Mina, 2017, bioRxiv.

Role of CYP27A in cholesterol and bile acid metabolism Published, JLR Papers in Press, November 1, 2004. DOI 10.1194/jlr.M400219-JLR200

R. Krauss, F. Suchy, N. Maeda, 2005, Journal of Lipid Research.

Altered hepatic cholesterol metabolism compensates for disruption of phosphatidylcholine transfer protein in mice.

D. Cohen, Michele K. Wu, D. Cohen, 2005, American journal of physiology. Gastrointestinal and liver physiology.

A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse

M. Lisanti, S. Yadav, P. G. Frank, 2005, Hepatology.

Lipid and Lipoprotein Metabolism in Liver Disease

D. Cohen, K. Corey, D. Cohen, 2015 .

Sterol carrier protein 2 participates in hypersecretion of biliary cholesterol during gallstone formation in genetically gallstone-susceptible mice.

F. Lammert, B. Paigen, D. Cohen, 1998, The Biochemical journal.

Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons.

R. Shivdasani, A. Roebroek, W. V. D. Van de Ven, 2007, Cell metabolism.

Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice

Blaine R. Roberts, E. Ortlund, T. Krisko, 2021, Nature Communications.

Transmembrane translocation of phosphatidylcholines and biliary lipid secretion: Evidence for “flippases” in the canalicular plasma membrane

D. Cohen, M. Fuchs, 1996, Hepatology.

Baculovirus-mediated expression of recombinant rat phosphatidylcholine transfer protein.

D. Cohen, L. Feng, L. Feng, 1998, Journal of lipid research.

Small-molecule inhibitors of phosphatidylcholine transfer protein/StarD2 identified by high-throughput screening.

M. Glicksman, N. Wagle, Jun Xian, 2008, Analytical biochemistry.

Mice lacking Pctp /StarD2 exhibit increased adaptive thermogenesis and enlarged mitochondria in brown adipose tissue[S]

A. Bianco, D. Cohen, Brian W Kim, 2009, Journal of Lipid Research.

Cloning and characterization of a cDNA encoding the specific phosphatidylcholine transfer protein from bovine liver.

R. Green, D. Cohen, D. Cohen, 1995, Gene.

Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels.

M. Lisanti, P. G. Frank, D. Cohen, 2001, Biochemistry.