C. Mcqueen

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Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis.

M. Angrish, B. Chorley, J. P. Kaiser, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Cell culture systems andin vitro toxicity testing

D. Acosta, O. Flint, J. Resau, 1992, Cytotechnology.

The effects of genetic variation in N-acetyltransferases on 4-aminobiphenyl genotoxicity in mouse liver.

R. Erickson, M. Philbert, C. Mcqueen, 2003, Chemico-biological interactions.

Pharmacogenetics of the arylamine N-acetyltransferases: a symposium in honor of Wendell W. Weber.

D. Grant, F. Kadlubar, C. Mcqueen, 2000, Drug metabolism and disposition: the biological fate of chemicals.

The hepatocyte primary culture/DNA repair assay using mouse or hamster hepatocytes.

G. Williams, C. Mcqueen, G M Williams, 1983, Environmental mutagenesis.

The hepatocyte primary culture/DNA repair test using hepatocytes from several species

Gary M Williams, C. Mcqueen, G. Williams, 1987, Cell Biology and Toxicology.

Sex and strain differences in the hepatocyte primary culture/DNA repair test

D. Casciano, C. Mcqueen, B. M. Way, 1991, Environmental and molecular mutagenesis.

3 – Toxicology Studies in Cultured Hepatocytes from Various Species

Gary M Williams, C. Mcqueen, G. Williams, 1987 .

THE USE OF CELLS FROM RAT, MOUSE, HAMSTER, AND RABBIT IN THE HEPATOCYTE PRIMARY CULTURE/DNA‐REPAIR TEST *

Gary M Williams, C. Mcqueen, G. Williams, 1983, Annals of the New York Academy of Sciences.

The genotoxicity of 4,4'-methylenebis-2-chloroaniline in rat, mouse, and hamster hepatocytes.

G. Williams, C. Mcqueen, C. J. Maslansky, 1981, Toxicology and applied pharmacology.

Relationship between the genetically determined acetylator phenotype and DNA damage induced by hydralazine and 2-aminofluorene in cultured rabbit hepatocytes.

G. Williams, C. Mcqueen, W. Weber, 1982, Proceedings of the National Academy of Sciences of the United States of America.

An N-ethyl-N-nitrosourea-induced mutation in N-acetyltransferase 1 in mice.

Y. Sakaki, A. Toyoda, Y. Gondo, 2008, Biochemical and biophysical research communications.

From the Cover: Genomic Effects of Androstenedione and Sex-Specific Liver Cancer Susceptibility in Mice

J. Corton, S. Hester, J. E. Simmons, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Hepatic gene expression and lipid homeostasis in C57BL/6 mice exposed to hydrazine or acetylhydrazine.

Victoria E. Richards, M. White, C. Mcqueen, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Recommendations for the performance of UDS tests in vitro and in vivo.

H. Mori, C. Mcqueen, G. Brambilla, 1994, Mutation research.

The role of acetylation in the mutagenicity of the antitumor agent, batracylin.

E. LaVoie, C. Mcqueen, G. Stevens, 1996, Carcinogenesis.

Characterization of human lymphocyte N-acetyltransferase and its relationship to the isoniazid acetylator polymorphism

C. Mcqueen, W. Weber, 1980, Biochemical Genetics.

Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.

L. Deangelis, J. Bertino, C. Mcqueen, 1976, Cancer research.

Genotoxicity of the antihypertensive drugs hydralazine and dihydralazine.

G. Williams, C. Mcqueen, G. Mazué, 1980, Science.

Toxicity of the heterocyclic amine batracylin: investigation of rodent N-acetyltransferase activity and potential contribution of cytochrome P450 3A

C. Mcqueen, J. Burkey, G. Stevens, 2004, Cell Biology and Toxicology.

Mutagenicity of 4-aminobiphenyl and 4-acetylaminobiphenyl in Salmonella typhimurium strains expressing different levels of N-acetyltransferase.

C. Mcqueen, L. N. Dang, 1999, Toxicology and applied pharmacology.

Tyrosine Hydroxylase: Subcellular Distribution and Molecular and Kinetic Characteristics of the Different Enzyme Forms

G. L. Craviso, J. Musacchio, C. Mcqueen, 1973 .

Cytotoxicity and genotoxicity of methyleugenol and related congeners-- a mechanism of activation for methyleugenol.

I. Sipes, J. Sauer, C. Mcqueen, 2000, Mutation research.

Bioassay of quinoline, 5-fluoroquinoline, carbazole, 9-methylcarbazole and 9-ethylcarbazole in newborn mice.

S. Meegalla, E. LaVoie, C. Mcqueen, 1993, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Measuring the Activity of Arylamine N‐Acetyltransferase (NAT)

C. Mcqueen, 2001, Current protocols in toxicology.

In memoriam: Wendell W. Weber, PhD, MD (1925-2018).

C. Mcqueen, P. Hollenberg, D. Hein, 2018, Pharmacogenetics and genomics.

Prenatal expression of N-acetyltransferases in C57Bl/6 mice.

M. Philbert, C. Mcqueen, R. Tjalkens, 2003, Chemico-biological interactions.

Extracellular metabolites of 2-aminofluorene in cultures of rapid and slow acetylator rabbit hepatocytes as a model for urinary and biliary metabolism.

G. Williams, M. Miller, C. Mcqueen, 1988, Chemico-biological interactions.

Confirmation of the role of N‐acetyltransferase 2 in teratogen‐induced cleft palate using transgenics and knockouts

R. Erickson, C. Mcqueen, E. Sim, 2008, Molecular reproduction and development.

Review of the genotoxicity and carcinogenicity of 4,4'-methylene-dianiline and 4,4'-methylene-bis-2-chloroaniline.

G. Williams, C. Mcqueen, Charlene A. McQueen, 1990, Mutation research.

Synthesis and pharmacological evaluation of isoindolo[1,2-b]quinazolinone and isoindolo[2,1-a]benzimidazole derivatives related to the antitumor agent batracylin.

S. Meegalla, C. Yu, L. Liu, 1994, Journal of medicinal chemistry.

The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events

Alan R. Boobis, Ted W. Simon, S. Stoney Simons, 2014, Critical reviews in toxicology.

Study of potential in vitro and in vivo genotoxicity in hepatocytes of quinolone antibiotics.

G. Williams, G. Schlüter, C. Mcqueen, 1991, Toxicology and applied pharmacology.

Cell culture systems and in vitro toxicity testing. Technical report no. 4 of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT): technical workshop of June 13-15, 1990.

Robert J. Hay, John Harbell, John M. Frazier, 1992, Cytotechnology.

Dihydropteridine reductase: implication on the regulation of catecholamine biosynthesis.

J. Musacchio, C. Mcqueen, G. D'Angelo, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Cytotoxicity of xenobiotics in adult rat hepatocytes in primary culture.

G. Williams, C. Mcqueen, 1982, Fundamental and applied toxicology : official journal of the Society of Toxicology.

The lack of genotoxicity of sodium fluoride in a battery of cellular tests

Gary M Williams, C. Mcqueen, C. Tong, 1988, Cell Biology and Toxicology.

Sex differences in the biotransformation of 2-acetylaminofluorene in cultured rat hepatocytes

Gary M Williams, C. Mcqueen, M. Miller, 1986, Cell Biology and Toxicology.

Suppression of Kupffer cell function prevents cadmium induced hepatocellular necrosis in the male Sprague-Dawley rat.

I. Sipes, M. Waalkes, J. Sauer, 1997, Toxicology.

The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps.

D. Tweedie, A. Alekseyenko, D. Mendrick, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

DNA constructs designed to produce short hairpin, interfering RNAs in transgenic mice sometimes show early lethality and an interferon response.

R. Erickson, C. Mcqueen, R. Hunter, 2005, Journal of applied genetics.

Neonatal ontogeny of murine arylamine N-acetyltransferases: implications for arylamine genotoxicity.

C. Mcqueen, B. Chau, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Genotoxicity of carcinogens in human hepatocytes: application in hazard assessment.

G. Williams, C. Mcqueen, B. M. Way, 1988, Toxicology and applied pharmacology.

Structure-activity relationships in the rat hepatocyte DNA-repair test for 300 chemicals.

G. Williams, H. Mori, C. Mcqueen, 1989, Mutation research.

Effect of nalidixic acid on DNA repair in rat hepatocytes

C. Mcqueen, G. Williams, Roxanne R. Rosado, 1989, Cell Biology and Toxicology.

Developmental expression of N-acetyltransferases in C57BI/6 mice.

B. Futscher, C. Mcqueen, M. K. Mitchell, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Biotransformation of aromatic amines to DNA-damaging products by urinary bladder organ cultures.

G. Williams, C. Mcqueen, B. M. Way, 1987, Carcinogenesis.

Characterization of DNA repair elicited by carcinogens and drugs in the hepatocyte primary culture/DNA repair test.

G. Williams, C. Mcqueen, 1981, Journal of toxicology and environmental health.

Genotoxicity of fluoroquinolines and methylquinolines.

E. LaVoie, C. Mcqueen, B. M. Way, 1991, Carcinogenesis.

The effect of acrylamide on hepatocellular DNA repair.

M. Miller, C. Mcqueen, M. Miller, 1986, Environmental mutagenesis.

Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice

R. Erickson, C. Mcqueen, R. Hunter, 2005, The Pharmacogenomics Journal.

Comparative effects of folate antagonists versus enzymatic folate depletion on folate and thymidine enzymes in cultured mammalian cells.

L. Deangelis, J. Bertino, C. Mcqueen, 1977, Cancer treatment reports.

Role of the acetylation polymorphism in determining susceptibility of cultured rabbit hepatocytes to DNA damage by aromatic amines.

G. Williams, C. Mcqueen, C. J. Maslansky, 1983, Cancer research.

New Methods and Models for the Isoniazid Acetylation Polymorphism

R. Tannen, C. Mcqueen, W. Weber, 1979 .

N-Acetylation of drugs. A genetically controlled reciprocal relationship between drug N-acetylating enzymes of rabbit liver and peripheral blood cells.

C. Mcqueen, W. Weber, G. Drummond, 1978, Drug metabolism and disposition: the biological fate of chemicals.

N-acetylation of the heterocyclic amine batracylin by human liver.

C. Mcqueen, E. Sim, G. Stevens, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Adverse Outcome Pathways—Organizing Toxicological Information to Improve Decision Making

Yu-Mei Tan, Stephen W. Edwards, Daniel L Villeneuve, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Toxicity studies of butylated hydroxyanisole and butylated hydroxytoluene. I. Genetic and cellular effects.

G. Williams, C. Mcqueen, C. Tong, 1990, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Triclosan-selected host-associated microbiota perform xenobiotic biotransformations in larval zebrafish.

Todd J. Zurlinden, S. Keely, A. Swank, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

Editor’s Highlight: Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis

Elaine Cohen-Hubal, Brian N. Chorley, Charlene A. McQueen, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Acetylation and its role in the mutagenicity of the antihypertensive agent hydralazine.

C. Mcqueen, L. Lemke, 1995, Drug metabolism and disposition: the biological fate of chemicals.

High-performance liquid chromatographic analysis of 2-aminofluorene and its metabolites in monolayer cultures of rat hepatocytes.

C. Mcqueen, M. Miller, 1986, Analytical biochemistry.

Dose and Effect Thresholds for Early Key Events in a PPARα-Mediated Mode of Action.

Elaina M Kenyon, Charlene A McQueen, Virunya S Bhat, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

N-acetyltransferase 2 activity and folate levels.

R. Erickson, C. Mcqueen, R. Hunter, 2010, Life sciences.

Isolation and Culture of Hepatocytes from Different Laboratory Species

C. Mcqueen, 1993 .