A. Perl

发表

Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis.

B. Stripp, M. Guo, J. Whitsett, 2016, JCI insight.

Temporal, spatial, and phenotypical changes of PDGFRα expressing fibroblasts during late lung development.

M. Weirauch, Erik L. Bao, Yan Xu, 2017, Developmental biology.

A "GLI-tch" in Alveolar Myofibroblast Differentiation.

A. Perl, S. Ahlfeld, 2017, American journal of respiratory cell and molecular biology.

Dataset on transcriptional profiles and the developmental characteristics of PDGFRα expressing lung fibroblasts☆

M. Weirauch, Erik L. Bao, Yan Xu, 2017, Data in brief.

Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development

Ravi S. Misra, S. Bhattacharya, T. Mariani, 2017, Thorax.

Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth

Samriddha Ray, S. Potter, H. Deshmukh, 2019, Nature Communications.

Signaling pathways in the epithelial origins of pulmonary fibrosis

J. Whitsett, V. Davé, J. Hagood, 2010, Cell cycle.

Neural Cell Adhesion Molecule (N-CAM) Is Required for Cell Type Segregation and Normal Ultrastructure in Pancreatic Islets

G. Christofori, A. Perl, H. Semb, 1999, The Journal of cell biology.

Single Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell.

D. Kwiatkowski, S. Potter, M. Guo, 2020, American journal of respiratory and critical care medicine.

Identification of the lymphangioleiomyomatosis cell and its uterine origin

D. Kwiatkowski, S. Potter, M. Guo, 2019, bioRxiv.

Diversity of Interstitial Lung Fibroblasts Is Regulated by Platelet-Derived Growth Factor Receptor α Kinase Activity.

H. Auer, A. Perl, M. Endale, 2016, American journal of respiratory cell and molecular biology.

Erm/Thyroid Transcription Factor 1 Interactions Modulate Surfactant Protein C Transcription*

A. Perl, J. Shannon, Sui Lin, 2006, Journal of Biological Chemistry.

β‐catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis

J. Whitsett, T. Kalin, V. Kalinichenko, 2016, Developmental dynamics : an official publication of the American Association of Anatomists.

Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung.

B. Stripp, J. Whitsett, Yan Xu, 2015, Journal of molecular cell biology.

Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli.

J. Whitsett, A. Perl, S. Wert, 2005, American journal of respiratory cell and molecular biology.

Conditional expression of genes in the respiratory epithelium in transgenic mice: cautionary notes and toward building a better mouse trap.

J. Whitsett, A. Perl, Liqian Zhang, 2009, American journal of respiratory cell and molecular biology.

FGF signaling is required for pulmonary homeostasis following hyperoxia.

J. Whitsett, A. Perl, I. Hokuto, 2004, American journal of physiology. Lung cellular and molecular physiology.

Prenatal, but Not Postnatal, Inhibition of Fibroblast Growth Factor Receptor Signaling Causes Emphysema*

J. Whitsett, A. Perl, I. Hokuto, 2003, The Journal of Biological Chemistry.

Diversity of Interstitial Lung Fibroblasts is Regulated by PDGFRα Kinase Activity

H. Auer, A. Perl, M. Endale, 2015 .

FGF signaling is required for myofibroblast differentiation during alveolar regeneration.

A. Perl, E. Gale, 2009, American journal of physiology. Lung cellular and molecular physiology.

Modulation of Endocrine Pancreas Development but not β-Cell Carcinogenesis by Sprouty4

G. Christofori, M. A. Cabrita, A. Perl, 2008, Molecular Cancer Research.

Role of Sonic hedgehog in patterning of tracheal–bronchial cartilage and the peripheral lung

J. Whitsett, Yan Xu, A. Perl, 2004, Developmental dynamics : an official publication of the American Association of Anatomists.

Temporal effects of Sprouty on lung morphogenesis.

G. Christofori, J. Whitsett, A. Perl, 2003, Developmental biology.

Pretreatment of aged mice with retinoic acid supports alveolar regeneration via upregulation of reciprocal PDGFA signalling

Yan Xu, L. Hariri, A. Perl, 2020, Thorax.

Matrix fibroblast function during alveolarization is dependent on GATA6

M. Guo, A. Perl, J. Green, 2022, bioRxiv.

C/EBP (cid:3) is required for lung maturation at birth

Yan Xu, J. Whitsett, H. Wan, 2006 .

MEG3 is increased in idiopathic pulmonary fibrosis and regulates epithelial cell differentiation.

J. Whitsett, Yan Xu, L. Hariri, 2018, JCI insight.

Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic β tumor cells

G. Christofori, P. Wilgenbus, A. Perl, 1999, Nature Medicine.

The Elephant in the Lung: Integrating lineage-tracing, molecular markers, and single cell sequencing data to identify distinct fibroblast populations during lung development and regeneration.

B. Aronow, A. Perl, M. Riccetti, 2020, Matrix biology : journal of the International Society for Matrix Biology.

A census of the lung: CellCards from LungMAP.

Eric E. Bardes, Jamie M. Verheyden, Ravi S. Misra, 2021, Developmental cell.

Active epithelial Hippo signaling in idiopathic pulmonary fibrosis.

B. Stripp, J. Whitsett, Yan Xu, 2018, JCI insight.

A causal role for E-cadherin in the transition from adenoma to carcinoma

Gerhard Christofori, Henrik Semb, G. Christofori, 1998, Nature.

Early restriction of peripheral and proximal cell lineages during formation of the lung

Susan E. Wert, Andras Nagy, Jeffrey A. Whitsett, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Molecular mechanisms controlling lung morphogenesis

J. Whitsett, A. Perl, 1999, Clinical genetics.

Molecular mechanisms controlling lung morphogenesis

J. Whitsett, A. Perl, 1999 .

The a"MAZE"ing world of lung-specific transgenic mice.

E. Rawlins, A. Perl, 2012, American journal of respiratory cell and molecular biology.

FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo.

J. Tichelaar, J. Whitsett, J. C. Clark, 2001, American journal of physiology. Lung cellular and molecular physiology.

C/EBPα is required for lung maturation at birth

J. Whitsett, Yan Xu, H. Wan, 2006 .

The Promise of Lung Organoids for Growth and Investigation of Pneumocystis Species

M. Cushion, A. Perl, T. Patterson, 2021, Frontiers in Fungal Biology.

Conditional depletion of airway progenitor cells induces peribronchiolar fibrosis.

D. Riethmacher, J. Whitsett, A. Perl, 2011, American journal of respiratory and critical care medicine.

Conditional control of gene expression in the respiratory epithelium: A cautionary note.

J. Whitsett, A. Perl, 2006, American journal of respiratory cell and molecular biology.

Conditional gene expression in the respiratory epithelium of the mouse

Jeffrey A. Whitsett, Anne-Karina T. Perl, J. Tichelaar, 2002, Transgenic Research.

Fibroblast Growth Factor 18 Influences Proximal Programming during Lung Morphogenesis*

J. Tichelaar, J. Whitsett, N. Itoh, 2002, The Journal of Biological Chemistry.

Stat-3 is required for pulmonary homeostasis during hyperoxia.

S. Akira, K. Takeda, J. Whitsett, 2004, The Journal of clinical investigation.

Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth

Samriddha Ray, S. Potter, H. Deshmukh, 2019, Nature Communications.

Dynamic regulation of platelet-derived growth factor receptor α expression in alveolar fibroblasts during realveolarization.

C. Lutzko, T. L. Le Cras, A. Perl, 2012, American journal of respiratory cell and molecular biology.

Normal lung development and function after Sox9 inactivation in the respiratory epithelium

R. Kist, J. Whitsett, A. Perl, 2005, Genesis.

C/EBPalpha is required for lung maturation at birth.

J. Whitsett, Yan Xu, H. Wan, 2006, Development.

Surfactant protein C mutation links postnatal type 2 cell dysfunction to adult disease

H. Deshmukh, Yan Xu, Sneha Sitaraman, 2021, JCI insight.

Transgenic models for study of lung morphogenesis and repair: Parker B. Francis lecture.

J. Tichelaar, J. Whitsett, J. C. Clark, 2001, Chest.

Lymphangioleiomyomatosis (LAM) Cell Atlas

D. Kwiatkowski, E. Henske, M. Guo, 2022, Thorax.

Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung.

B. Stripp, J. Whitsett, Yan Xu, 2015, Journal of molecular cell biology.

Modulation of Endocrine Pancreas Development but not β-Cell Carcinogenesis by Sprouty4

G. Christofori, M. A. Cabrita, A. Perl, 2008, Molecular Cancer Research.

Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lung

L. Deterding, S. Garantziotis, A. Perl, 2022 .