D. Sommermeyer

发表

Accepted Article Preview : Published ahead of advance online publication

D. Maloney, C. Turtle, S. Riddell, 2016 .

Dual T Cell Receptor Expressing CD8+ T Cells with Tumor- and Self-Specificity Can Inhibit Tumor Growth without Causing Severe Autoimmunity1

T. Blankenstein, W. Uckert, D. Sommermeyer, 2007, The Journal of Immunology.

Severe Autoimmunity Inhibit Tumor Growth without Causing Cells with Tumor-and Self-Specificity Can T + Dual T Cell Receptor Expressing CD 8 and Thomas Blankenstein

T. Blankenstein, W. Uckert, D. Sommermeyer, 2007 .

T-Cells Expressing a Highly Potent PRAME-Specific T-Cell Receptor in Combination with a Chimeric PD1-41BB Co-Stimulatory Receptor Show a Favorable Preclinical Safety Profile and Strong Anti-Tumor Reactivity

E. Noessner, D. Sommermeyer, M. Salvermoser, 2022, Cancers.

Safety of Targeting ROR1 in Primates with Chimeric Antigen Receptor–Modified T Cells

S. Riddell, D. Sommermeyer, M. Hudecek, 2014, Cancer Immunology Research.

Safety of Targeting ROR 1 in Primates with Chimeric Antigen Receptor – Modi fi ed T Cells

S. Riddell, D. Sommermeyer, M. Hudecek, 2015 .

Immunotherapy with CD19-specific chimeric antigen receptor (CAR)-modified T cells of defined subset composition.

S. Heimfeld, B. Wood, D. Maloney, 2015 .

Anti-CD19 Chimeric Antigen Receptor-Modified T Cell Therapy for B Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia: Fludarabine and Cyclophosphamide Lymphodepletion Improves In Vivo Expansion and Persistence of CAR-T Cells and Clinical Outcomes

S. Heimfeld, B. Wood, D. Maloney, 2015 .

Development of T-cell immunotherapy for hematopoietic stem cell transplantation recipients at risk of leukemia relapse.

D. Sommermeyer, M. Biernacki, Kimberly A. Foster, 2018, Blood.

Human Antitumor CD8+ T Cells Producing Th1 Polycytokines Show Superior Antigen Sensitivity and Tumor Recognition

W. Uckert, M. Leisegang, D. Sommermeyer, 2012, The Journal of Immunology.

Sensitivity and Tumor Recognition Th1 Polycytokines Show Superior Antigen T Cells Producing + Human Antitumor CD8

W. Uckert, M. Leisegang, D. Sommermeyer, 2012 .

Development of a CD8 co-receptor independent T-cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T-cell-based immunotherapy

P. Nambiar, I. Diaconu, Tristan Holland, 2021, Journal for ImmunoTherapy of Cancer.

A Single TCRa-Chain with Dominant Peptide Recognition in the Allorestricted HER2/neu-Specific T Cell Repertoire

A. Schub, Ingrid G. Schuster, A. Moosmann, 2009 .

NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability

W. Uckert, D. Sommermeyer, H. Bernhard, 2012, International journal of cancer.

CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.

Daniel Li, Jianhong Cao, Xueyan Chen, 2016, The Journal of clinical investigation.

Fully human CD19-specific chimeric antigen receptors for T-cell therapy

S. Riddell, S. Shamah, K. Mohler, 2017, Leukemia.

Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function

Jeffrey R. Whiteaker, Jacob J. Kennedy, A. Paulovich, 2021, Science Signaling.

Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function

Jeffrey R. Whiteaker, Uliana J. Voytovich, Jacob J. Kennedy, 2018, Science Signaling.

Role of memory T cell subsets for adoptive immunotherapy.

V. Buchholz, D. Busch, S. Riddell, 2016, Seminars in immunology.

Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo

D. Maloney, C. Turtle, S. Riddell, 2015, Leukemia.

Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells

S. Riddell, M. Jensen, D. Sommermeyer, 2013, Clinical Cancer Research.

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

R. Weichselbaum, Hua Yu, N. Hübner, 2017, Nature.

Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia.

D. Busch, M. Sadelain, S. Riddell, 2016, The Journal of clinical investigation.

Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues

P. Porter, S. Riddell, Anusha Rajan, 2016, Clinical Cancer Research.

Abstract 1520: Targetable immunogenic tumor specific antigens can be identified in non-coding regions of the genome

C. Perreault, Qingchuan Zhao, D. Sommermeyer, 2021, Immunology.

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis

C. Loddenkemper, T. Blankenstein, W. Uckert, 2011, International journal of cancer.

The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for In Vivo Antitumor Activity

S. Riddell, M. Jensen, D. Sommermeyer, 2014, Cancer Immunology Research.

Generation of dual T cell receptor (TCR) T cells by TCR gene transfer for adoptive T cell therapy

D. Sommermeyer, 2010 .

Designer T cells by T cell receptor replacement

M. Heemskerk, T. Blankenstein, B. Engels, 2006, European journal of immunology.

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer

T. Blankenstein, W. Uckert, J. Charo, 2008, Proceedings of the National Academy of Sciences.

Inclusion of Strep-Tag II in design of antigen receptors for T cell immunotherapy

Tyler Hill, S. Riddell, D. Sommermeyer, 2016, Nature Biotechnology.

Misinitiation of intrathymic MART‐1 transcription and biased TCR usage explain the high frequency of MART‐1‐specific T cells

B. Kyewski, T. Blankenstein, W. Uckert, 2014, European journal of immunology.

Adoptive therapy with chimeric antigen receptor-modified T cells of defined subset composition.

D. Maloney, C. Turtle, S. Riddell, 2014, Cancer journal.

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity.

D. Busch, W. Uckert, M. Schiemann, 2009, Blood.

Minimal Amino Acid Exchange in Human TCR Constant Regions Fosters Improved Function of TCR Gene-Modified T Cells

W. Uckert, D. Sommermeyer, 2010, The Journal of Immunology.

Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette

B. Engels, W. Uckert, M. Leisegang, 2008, Journal of Molecular Medicine.

A Single TCRα-Chain with Dominant Peptide Recognition in the Allorestricted HER2/neu-Specific T Cell Repertoire

D. Busch, A. Schub, Ingrid G. Schuster, 2009, The Journal of Immunology.

avidity functional induce T cells with superior antitumor activity and higher TCR Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen

D. Busch, M. Schiemann, D. Sommermeyer, 2013 .

Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette

B. Engels, W. Uckert, M. Leisegang, 2008, Journal of Molecular Medicine.

in adult B cell ALL patients

S. Heimfeld, B. Wood, D. Maloney, 2016 .

Function of TCR Gene-Modified T Cells TCR Constant Regions Fosters Improved Minimal Amino Acid Exchange in Human

W. Uckert, D. Sommermeyer, 2010 .

Tumor recognition by ROR 1-specific CARs 1 Receptor affinity and extracellular domain modifications affect tumor recognition by ROR 1-specific chimeric antigen receptor T-cells

S. Riddell, M. Jensen, D. Sommermeyer, 2013 .

Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes.

B. Baker, D. Kranz, W. Uckert, 2013, Journal of molecular biology.

Rate of durable complete response in ALL, NHL, and CLL after immunotherapy with optimized lymphodepletion and defined composition CD19 CAR-T cells.

K. Loeb, S. Heimfeld, B. Wood, 2016 .

Therapy of B Cell Malignancies with CD19-Specific Chimeric Antigen Receptor-Modified T Cells of Defined Subset Composition

S. Heimfeld, D. Maloney, C. Turtle, 2014 .