Xiaohua Wu

发表

CtIP Protein Dimerization Is Critical for Its Recruitment to Chromosomal DNA Double-stranded Breaks*

Linda Z. Shi, David J. Chen, M. Berns, 2012, The Journal of Biological Chemistry.

Cell Cycle-dependent Complex Formation of BRCA1·CtIP·MRN Is Important for DNA Double-strand Break Repair*

Xiaohua Wu, Longchuan Chen, Christian J Nievera, 2008, Journal of Biological Chemistry.

The SCFSkp2 Ubiquitin Ligase Complex Interacts with the Human Replication Licensing Factor Cdt1 and Regulates Cdt1 Degradation*

Xiaohua Wu, Xianghong Li, Qi-Peng Zhao, 2003, Journal of Biological Chemistry.

Rad50 Zinc Hook Is Important for the Mre11 Complex to Bind Chromosomal DNA Double-stranded Breaks and Initiate Various DNA Damage Responses*

Linda Z. Shi, J. Shiloach, M. Berns, 2012, The Journal of Biological Chemistry.

The RING Finger Protein RNF8 Ubiquitinates Nbs1 to Promote DNA Double-strand Break Repair by Homologous Recombination*

Linda Z. Shi, J. Yates, T. Hunter, 2012, The Journal of Biological Chemistry.

The Interaction of CtIP and Nbs1 Connects CDK and ATM to Regulate HR–Mediated Double-Strand Break Repair

Linda Z. Shi, David J. Chen, J. Yates, 2013, PLoS genetics.

Dbf4 Is Direct Downstream Target of Ataxia Telangiectasia Mutated (ATM) and Ataxia Telangiectasia and Rad3-related (ATR) Protein to Regulate Intra-S-phase Checkpoint*

L. Truong, T. Chiba, Xiaohua Wu, 2011, The Journal of Biological Chemistry.

The Mre11-Rad50-Nbs1 Complex Acts Both Upstream and Downstream of Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR) to Regulate the S-phase Checkpoint following UV Treatment*

Xiaohua Wu, E. Olson, Longchuan Chen, 2007, Journal of Biological Chemistry.

RPA2 Is a Direct Downstream Target for ATR to Regulate the S-phase Checkpoint*

E. Fanning, Xiaohua Wu, E. Olson, 2006, Journal of Biological Chemistry.

Protein Phosphatase 2A-Dependent Dephosphorylation of Replication Protein A Is Required for the Repair of DNA Breaks Induced by Replication Stress

Xiao-Fan Wang, S. Kornbluth, Xiaohua Wu, 2009, Molecular and Cellular Biology.

p38γ regulates UV-induced checkpoint signaling and repair of UV-induced DNA damage

Jiahuai Han, Xiaohua Wu, P. Sun, 2010, Protein & Cell.

SV40 T antigen interacts with Nbs1 to disrupt DNA replication control.

H. Heng, D. Livingston, T. Chiba, 2004, Genes & development.

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

R. DePinho, D. Livingston, K. Rudolph, 2001, Current Biology.

CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity.

Jing He, Linda Z Shi, Michael W Berns, 2014, Molecular cell.

Cyclin E Deregulation Promotes Loss of Specific Genomic Regions

Pei Wang, S. Reed, L. K. Teixeira, 2015, Current Biology.

The role of RPA2 phosphorylation in homologous recombination in response to replication arrest.

S. Gonzalo, S. Powell, Zhihui Feng, 2010, Carcinogenesis.

The concerted roles of FANCM and Rad52 in the protection of common fragile sites

Lei Li, Shibo Li, Lei Li, 2018, Nature Communications.

ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures

T. Chiba, Shibo Li, R. Xiang, 2019, iScience.

Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

Linda Z. Shi, Michael W. Berns, Hailong Wang, 2013, Proceedings of the National Academy of Sciences.

Replication Stress Response Links RAD52 to Protecting Common Fragile Sites

Xiaohua Wu, 2019, Cancers.

BLM prevents instability of structure-forming DNA sequences at common fragile sites

Shibo Li, Xiaohua Wu, Hailong Wang, 2018, PLoS genetics.

Break‐induced replication plays a prominent role in long‐range repeat‐mediated deletion

L. Truong, Shibo Li, R. Xiang, 2019, The EMBO journal.

DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse

T. Chiba, Shibo Li, R. Xiang, 2019, The Journal of Biological Chemistry.

DNA repair protein RAD52 is required for protecting G-quadruplexes in mammalian cells

Sameer B. Shah, Shuo Liu, Xiaohua Wu, 2022, The Journal of biological chemistry.

Break-induced replication mechanisms in yeast and mammals.

A. Malkova, Xiaohua Wu, 2021, Current opinion in genetics & development.

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

D. Livingston, William Arbuthnot Sir Lane, D. Weaver, 2000, Nature.

MADM, a Novel Adaptor Protein That Mediates Phosphorylation of the 14-3-3 Binding Site of Myeloid Leukemia Factor 1*

Louise N. Winteringham, Yi Sun, S. Klinken, 2002, The Journal of Biological Chemistry.

The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair.

S. Elledge, A. D’Andrea, N. Willis, 2021, Molecular cell.

Common fragile sites: protection and repair

Shibo Li, Xiaohua Wu, 2020, Cell & Bioscience.

PIF1 helicase promotes break‐induced replication in mammalian cells

L. Truong, T. Chiba, Shibo Li, 2021, The EMBO journal.

Homologous Recombination Is a Primary Pathway to Repair DNA Double-Strand Breaks Generated during DNA Rereplication*

L. Truong, Patty Yi-Hwa Hwang, Xiaohua Wu, 2014, The Journal of Biological Chemistry.

Cyclin-dependent Kinases Phosphorylate Human Cdt1 and Induce Its Degradation*

Xiaohua Wu, Xianghong Li, Qi-Peng Zhao, 2004, Journal of Biological Chemistry.

The Mre11 Complex Mediates the S-Phase Checkpoint through an Interaction with Replication Protein A

Xiaohua Wu, E. Olson, Longchuan Chen, 2007, Molecular and Cellular Biology.

Independence of R/M/N Focus Formation and the Presence of Intact BRCA1

D. Livingston, Junjie Chen, D. Weaver, 2000, Science.

The Mre11/Rad50/Nbs1 Complex Plays an Important Role in the Prevention of DNA Rereplication in Mammalian Cells*

Xiaohua Wu, A. Lee, E. Liu, 2007, Journal of Biological Chemistry.

Prevention of DNA re-replication in eukaryotic cells.

L. Truong, Xiaohua Wu, 2011, Journal of molecular cell biology.

The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted

T. Chiba, Xiaohua Wu, E. Olson, 2007, The Journal of cell biology.

Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection.

Hailong Wang, Ji-Hoon Lee, Yi Zhou, 2014, Molecular cell.

Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage.

A. Su, L. Truong, Tao Xu, 2014, Molecular cell.

The concerted roles of FANCM and Rad52 in the protection of common fragile sites

Lei Li, Shibo Li, Hailong Wang, 2018, Nature Communications.

Jcb: Article

G. C. Rogers, Erin L. Barnhart, Natalie A. Dye, 2022 .

DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse

T. Chiba, Shibo Li, R. Xiang, 2019, Journal of Biological Chemistry.

Common fragile sites: protection and repair

Shibo Li, Xiaohua Wu, 2020, Cell & Bioscience.

The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted

T. Chiba, Xiaohua Wu, E. Olson, 2007, The Journal of cell biology.

CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity.

J. Shiloach, M. Berns, L. Truong, 2014, Molecular cell.

Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forks

Xiaohua Wu, Hailong Wang, Shuailin Hao, 2023, Nucleic acids research.

MutSβ protects common fragile sites by facilitating homology-directed repair at DNA double-strand breaks with secondary structures

Hailong Wang, Xiaohua Wu, Youhang Li, 2023, Nucleic acids research.