S. Pyronnet

发表

Restoration of Functional Gap Junctions through Internal Ribosome Entry Site-Dependent Synthesis of Endogenous Connexins in Density-Inhibited Cancer Cells

L. Pradayrol, C. Susini, H. Lahlou, 2005, Molecular and Cellular Biology.

Suppression of cap-dependent translation in mitosis.

N. Sonenberg, J. Dostie, S. Pyronnet, 2001, Genes & development.

A cell cycle-dependent internal ribosome entry site.

N. Sonenberg, L. Pradayrol, S. Pyronnet, 2000, Molecular cell.

Somatostatin analogs: does pharmacology impact antitumor efficacy?

P. Caron, C. Bousquet, S. Pyronnet, 2014, Trends in Endocrinology & Metabolism.

Clinical review: Current scientific rationale for the use of somatostatin analogs and mTOR inhibitors in neuroendocrine tumor therapy.

P. Caron, C. Bousquet, C. Susini, 2012, The Journal of clinical endocrinology and metabolism.

Essential role for SphK1/S1P signaling to regulate hypoxia-inducible factor 2α expression and activity in cancer

O. Cuvillier, L. Brizuela, Y. Martineau, 2016, Oncogenesis.

Key contribution of eIF4H-mediated translational control in tumor promotion

Thomas Filleron, Robert C. Rintoul, Marie Bernadette Delisle, 2015, Oncotarget.

The PERK Branch of the Unfolded Protein Response Promotes DLL4 Expression by Activating an Alternative Translation Mechanism

C. Touriol, L. Mazzolini, S. Pyronnet, 2019, Cancers.

PERK mediates the IRES-dependent translational activation of mRNAs encoding angiogenic growth factors after ischemic stress

P. Brousset, H. Prats, C. Touriol, 2016, Science Signaling.

Nucleolin Promotes Heat Shock-Associated Translation of VEGF-D to Promote Tumor Lymphangiogenesis.

S. Marzi, A. Prats, L. Ligat, 2016, Cancer research.

Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism.

P. Carmeliet, S. Marzi, A. Prats, 2014, Cell reports.

Anti-oncogenic potential of the eIF4E-binding proteins

Y. Martineau, C. Bousquet, S. Pyronnet, 2013, Oncogene.

A cell cycle-dependent internal ribosome entry site

N. Sonenberg, L. Pradayrol, S. Pyronnet, 2000 .

Antitumor effects of somatostatin

S. Najib, C. Bousquet, C. Susini, 2008, Molecular and Cellular Endocrinology.

Endocrine tumours of the gastrointestinal tract. Somatostatin receptors as tools for diagnosis and therapy: molecular aspects.

C. Bousquet, C. Susini, H. Lahlou, 2005, Best practice & research. Clinical gastroenterology.

sst2 Somatostatin Receptor Inhibits Cell Proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 Activation*

A. Eychène, L. Pradayrol, N. Saint-Laurent, 2003, Journal of Biological Chemistry.

Pharmacological targeting of protein synthesis in cancer-associated fibroblasts abrogates pancreatic tumor chemoresistance

Y. Martineau, C. Bousquet, S. Pyronnet, 2014 .

S6K1 Is Required for Increasing Skeletal Muscle Force during Hypertrophy.

M. Pende, S. Pyronnet, B. Blaauw, 2016, Cell reports.

S 6 K 1 Is Required for Incre asing Skeletal Muscle Force during Hypertrophy Graphical Abstract Highlights

M. Pende, S. Pyronnet, B. Blaauw, 2022 .

Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA

A. Gingras, N. Sonenberg, A. Kowalski-Chauvel, 1998, Oncogene.

Pancreatic tumours escape from translational control through 4E-BP1 loss

J. Pelletier, Y. Martineau, C. Bousquet, 2014, Oncogene.

Increase in PI3K signalling mimics mutated-Kras induction of pancreatic cancer.

S. Pyronnet, J. Guillermet-Guibert, R. Baer, 2013, Clinics and research in hepatology and gastroenterology.

Changes in Translational Control after Pro-Apoptotic Stress

Y. Martineau, C. Bousquet, S. Pyronnet, 2012, International journal of molecular sciences.

Assessment of alternatives to environmental toxic formalin for DNA conservation in biological specimens

E. Sarot, S. Pyronnet, Amandine Péquignot, 2017, Environmental Science and Pollution Research.

Focal Adhesion Kinase: A promising therapeutic target in pancreatic adenocarcinoma.

C. Jean, C. Bousquet, S. Pyronnet, 2017, Clinics and research in hepatology and gastroenterology.

Phosphorylation of the cap-binding protein eIF4E by the MAPK-activated protein kinase Mnk1.

S. Pyronnet, Stéphane Pyronnet, 2000, Biochemical pharmacology.

Imbalanced splicing in MAPK signaling sustains Ras-induced transformation.

Y. Martineau, C. Bousquet, S. Pyronnet, 2015, Clinics and research in hepatology and gastroenterology.

Gene therapy based on gemcitabine chemosensitization suppresses pancreatic tumor growth.

L. Pradayrol, L. Buscail, G. Tiraby, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Implication of 4E-BP1 protein dephosphorylation and accumulation in pancreatic cancer cell death induced by combined gemcitabine and TRAIL

M. Clemens, S. Pyronnet, S. Mudan, 2017, Cell Death & Disease.

Translatome-based classification reveals a dual metabolic dependency of a new tumor subtype of pancreatic cancer

J. Iovanna, N. Dusetti, O. Larsson, 2020, bioRxiv.

4E-BP restrains eIF4E phosphorylation

R. Schneider, Y. Martineau, C. Bousquet, 2013, Translation.

Pharmacological targeting of the protein synthesis mTOR/4E-BP1 pathway in cancer-associated fibroblasts abrogates pancreatic tumour chemoresistance

R. Tomasini, Y. Martineau, C. Bousquet, 2015, EMBO molecular medicine.

Human eukaryotic translation initiation factor 4 G ( eIF 4 G ) recruits Mnk 1 to phosphorylate eIF 4 E

A. Gingras, N. Sonenberg, T. Hunter, 2013 .

eIF4E association with 4E-BP decreases rapidly following fertilization in sea urchin.

N. Sonenberg, J. Morales, P. Cormier, 2001, Developmental biology.

Arachidonic‐acid‐selective cytosolic phospholipase A2 is involved in gastrin‐induced AR4‐2J‐cell proliferation

L. Pradayrol, N. Vaysse, S. Pyronnet, 1998, International journal of cancer.

Contribution of HIF-1α in 4E-BP1 Gene Expression

C. Bousquet, S. Pyronnet, C. Lasfargues, 2012, Molecular Cancer Research.

Contribution of HIF-1 α in 4 EBP 1 gene expression

C. Bousquet, S. Pyronnet, C. Lasfargues, 2012 .

Phosphatidylinositol 3-kinase-dependent transcriptional silencing of the translational repressor 4E-BP1

S. Najib, C. Susini, H. Lahlou, 2008, Cellular and Molecular Life Sciences.

Control of contact-inhibition by 4E-BP1 upregulation

C. Bousquet, C. Susini, S. Pyronnet, 2010, Cell cycle.

NAD(P)H Quinone-Oxydoreductase 1 Protects Eukaryotic Translation Initiation Factor 4GI from Degradation by the Proteasome (cid:1)

C. Bousquet, C. Susini, S. Pyronnet, 2010 .

NAD(P)H Quinone-Oxydoreductase 1 Protects Eukaryotic Translation Initiation Factor 4GI from Degradation by the Proteasome

C. Bousquet, C. Susini, S. Pyronnet, 2009, Molecular and Cellular Biology.

Translational alterations in pancreatic cancer: a central role for the integrated stress response

Y. Martineau, C. Bousquet, S. Pyronnet, 2022, NAR cancer.

Challenging the Roles of NSP3 and Untranslated Regions in Rotavirus mRNA Translation

E. Sarot, S. Pyronnet, P. Vende, 2016, PloS one.

High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor

L. Pradayrol, L. Buscail, M. Poirot, 2003, Oncogene.

Differential Regulation of the Three Eukaryotic mRNA Translation Initiation Factor (eIF) 4Gs by the Proteasome

C. Jean, R. Schneider, Y. Martineau, 2019, Front. Genet..

EZH2 links pancreatitis to tissue regeneration and pancreatic cancer.

S. Pyronnet, C. Lasfargues, 2012, Clinics and research in hepatology and gastroenterology.

The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

N. Sonenberg, A. Pause, Y. Svitkin, 2001, RNA.

Translational Homeostasis: Eukaryotic Translation Initiation Factor 4E Control of 4E-Binding Protein 1 and p70 S6 Kinase Activities

A. Gingras, N. Sonenberg, S. Pyronnet, 1999, Molecular and Cellular Biology.

Cap-dependent translation and control of the cell cycle.

N. Sonenberg, P. Cormier, O. Mulner-lorillon, 2003, Progress in cell cycle research.

Cell cycle-dependent translational control

N. Sonenberg, S. Pyronnet, 2000 .

Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts

C. Jean, Y. Martineau, C. Bousquet, 2016, Oncotarget.

- Claude Activities 4 E-Binding Protein 1 and p 70 S 6 Kinase Translation Initiation Factor 4 E Control of Translational Homeostasis : Eukaryotic

A. Gingras, N. Sonenberg, S. Pyronnet, 1999 .

Gene Expression Signature Associated with Clinical Outcome in ALK-Positive Anaplastic Large Cell Lymphoma

P. Brousset, S. Pyronnet, L. Lamant, 2021, Cancers.

ER Stress and Unfolded Protein Response in Leukemia: Friend, Foe, or Both?

C. Touriol, L. Mazzolini, S. Pyronnet, 2021, Biomolecules.

Overexpression of high molecular weight FGF-2 forms inhibits glioma growth by acting on cell-cycle progression and protein translation.

A. Bikfalvi, S. Pyronnet, F. Belloc, 2008, Experimental cell research.

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

D. Saur, B. Vanhaesebroeck, C. Bousquet, 2014, Genes & development.

Implication of 4 EBP 1 protein dephosphorylation and accumulation in 1 pancreatic cancer cell death induced by combined gemcitabine and 2 TRAIL 3 4

M. Clemens, S. Pyronnet, S. Mudan, 2017 .

4E‐BP1 is a target of Smad4 essential for TGFβ‐mediated inhibition of cell proliferation

C. Bousquet, C. Susini, S. Pyronnet, 2009, The EMBO journal.

Molecular Signaling of Somatostatin Receptors

C. Bousquet, C. Susini, H. Lahlou, 2004, Annals of the New York Academy of Sciences.

Somatostatin Receptor Signaling via Protein Tyrosine Phosphatases

C. Bousquet, L. Buscail, C. Susini, 2004 .

A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes.

N. Sonenberg, A. Krensky, T. Nikolcheva, 2002, The Journal of clinical investigation.

From circRNAs to fusion circRNAs in hematological malignancies

S. Pyronnet, F. Meggetto, E. Brunet, 2021, JCI insight.

A novel leukemic route of mutant NPM1 through nuclear import of the overexpressed long noncoding RNA LONA

P. Brousset, C. Touriol, H. de Thé, 2021, Leukemia.

Pharmacological study of gastrin-mediated amylase release in pancreatic acinar cells (AR4-2J)

L. Pradayrol, N. Vaysse, S. Pyronnet, 1994, Regulatory Peptides.

Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.

S. Yonehara, C. Bousquet, M. Fanjul, 2015, Gastroenterology.

Fibroblast growth factor 1 induced during myogenesis by a transcription–translation coupling mechanism

M. Khoury, A. Prats, Y. Martineau, 2009, Nucleic acids research.

A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway

S. Schulz, S. Najib, C. Bousquet, 2011, Molecular and Cellular Biology.

Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers

C. Touriol, L. Mazzolini, S. Pyronnet, 2020, Cells.

Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E

A. Gingras, N. Sonenberg, T. Hunter, 1999, The EMBO journal.

Netrin-1 mediates early events in pancreatic adenocarcinoma progression, acting on tumor and endothelial cells.

V. Castronovo, A. Bikfalvi, C. Bousquet, 2010, Gastroenterology.

eIF4E/4E-BP dissociation and 4E-BP degradation in the first mitotic division of the sea urchin embryo.

N. Sonenberg, J. Morales, P. Cormier, 2003, Developmental biology.

Rotavirus NSP3 Is a Translational Surrogate of the Poly(A) Binding Protein-Poly(A) Complex

E. Sarot, S. Pyronnet, P. Vende, 2015, Journal of Virology.

Dual roles of hemidesmosomal proteins in the pancreatic epithelium: the phosphoinositide 3-kinase decides

A. Sonnenberg, C. Bousquet, C. Susini, 2014, Oncogene.

Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer

P. Rochaix, A. Bikfalvi, A. Schally, 2009, Proceedings of the National Academy of Sciences.

Regulation of SOCS-1 Expression by Translational Repression*

N. Sonenberg, A. Gregorieff, S. Pyronnet, 2000, The Journal of Biological Chemistry.

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

P. Lambin, N. Sonenberg, J. Voncken, 2006, The EMBO journal.

eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer.

N. Sonenberg, O. Larsson, C. Jean, 2019, JCI insight.

FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer

D. Schlaepfer, R. Tomasini, C. Jean, 2020, EMBO molecular medicine.

Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages

I. Bièche, R. Tomasini, C. Jean, 2021, Cellular and molecular gastroenterology and hepatology.

Alternative splicing facilitates internal ribosome entry on the ornithine decarboxylase mRNA

N. Sonenberg, L. Pradayrol, S. Pyronnet, 2005, Cellular and Molecular Life Sciences CMLS.

CXCL4L1-fibstatin cooperation inhibits tumor angiogenesis, lymphangiogenesis and metastasis.

A. Prats, H. Prats, A. Bikfalvi, 2013, Microvascular research.

Relief of ornithine decarboxylase messenger RNA translational repression induced by alternative splicing of its 5' untranslated region.

A. Prats, L. Pradayrol, N. Vaysse, 1996, Cancer research.

Physiology of somatostatin receptors.

C. Bousquet, C. Susini, P. Cordelier, 2005, Journal of endocrinological investigation.

Phosphorylation of the MNK1 substrate eIF4E is not required for response to acute pancreatitis.

C. Jean, Y. Martineau, C. Bousquet, 2021, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E

J. Morales, M. Czjzek, P. Cormier, 2013, Nucleic acids research.

Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E

Gildas Le Corguillé, J. Morales, M. Czjzek, 2013, Nucleic acids research.

Control of Paip1-Eukayrotic Translation Initiation Factor 3 Interaction by Amino Acids through S6 Kinase

N. Sonenberg, T. Alain, B. Monsarrat, 2014, Molecular and Cellular Biology.

Cell-cycle-dependent translational control.

N. Sonenberg, S. Pyronnet, Nahum Sonenberg, 2001, Current opinion in genetics & development.