J. Bokar

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The biosynthesis and functional roles of methylated nucleosides in eukaryotic mRNA

J. Bokar, 2005 .

Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase.

F. Rottman, A. Matera, J. Bokar, 1997, RNA.

Characterization and partial purification of mRNA N6-adenosine methyltransferase from HeLa cell nuclei. Internal mRNA methylation requires a multisubunit complex.

F. Rottman, J. Bokar, P. Narayan, 1994, The Journal of biological chemistry.

Phase I clinical trial of temozolomide and methoxyamine (TRC-102), an inhibitor of base excision repair, in patients with advanced solid tumors

N. Sharma, J. Pink, P. Fu, 2020, Investigational new drugs.

Phase I trial of pomalidomide given for patients with advanced solid tumors

M. Cooney, R. Dreicer, A. Dowlati, 2012, Cancer Chemotherapy and Pharmacology.

Toxicity of sunitinib plus bevacizumab in renal cell carcinoma.

Helen X. Chen, B. Rini, M. Cooney, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A Phase I Study of the combination of oxaliplatin/docetaxel and vandetanib for the treatment of advanced gastroesophageal cancer

B. Halmos, P. Fu, A. Dowlati, 2013, Investigational New Drugs.

Advances in Oncology CareTargeted Therapies

C. Winkelman, J. Bokar, P. Mazanec, 2011 .

Advances in oncology care: targeted therapies.

C. Winkelman, J. Bokar, P. Mazanec, 2011, AACN advanced critical care.

Different combinations of regulatory elements may explain why placenta-specific expression of the glycoprotein hormone alpha-subunit gene occurs only in primates and horses.

R. Keri, C. Clay, D. Hamernik, 1991, Biology of reproduction.

Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

E. Vallen, J. Bokar, A. Milsted, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the cAMP responsive elements from the genes for the alpha-subunit of glycoprotein hormones and phosphoenolpyruvate carboxykinase (GTP). Conserved features of nuclear protein binding between tissues and species.

W. Roesler, R. Hanson, D. Kaetzel, 1988, The Journal of biological chemistry.

A phase II trial of fosbretabulin in advanced anaplastic thyroid carcinoma and correlation of baseline serum-soluble intracellular adhesion molecule-1 with outcome.

P. Fu, M. Cooney, A. Dowlati, 2009, Thyroid : official journal of the American Thyroid Association.

SR proteins Asf/SF2 and 9G8 interact to activate enhancer-dependent intron D splicing of bovine growth hormone pre-mRNA in vitro.

F. Rottman, J. Bokar, X. Li, 2000, RNA.

Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene.

C. Timpte, J. Bokar, Mary J Clancy, 2002, Nucleic acids research.

Phase II study of dasatinib (BMS-354825) in patients with metastatic adenocarcinoma of the pancreas.

J. Wright, P. Fu, A. Dowlati, 2013, The oncologist.

Phase I trial of daily lenalidomide and docetaxel given every three weeks in patients with advanced solid tumors

M. Cooney, S. Remick, S. Krishnamurthi, 2007 .

A Phase I Study of Sunitinib plus Bevacizumab in Advanced Solid Tumors

Helen X. Chen, B. Rini, E. Borden, 2009, Clinical Cancer Research.

Biosynthesis and Functions of Modified Nucleosides in Eukaryotic mRNA

F. Rottman, J. Bokar, 1998 .

Amplification of the transcriptional signal mediated by the tandem cAMP response elements of the glycoprotein hormone alpha-subunit gene occurs through several distinct mechanisms.

D. Hamernik, J. Bokar, R. Bohinski, 1990, Molecular endocrinology.

Expression of the glycoprotein hormone alpha-subunit gene in the placenta requires a functional cyclic AMP response element, whereas a different cis-acting element mediates pituitary-specific expression

R. Keri, T. Wagner, D. Hamernik, 1989, Molecular and cellular biology.

CRE‐Binding Proteins Interact Cooperatively to Enhance Placental‐Specific Expression of the Glycoprotein Hormone Alpha‐Subunit Gene a

R. Keri, R. Fenstermaker, J. Bokar, 1989, Annals of the New York Academy of Sciences.

N6-adenosine methylation in mRNA: substrate specificity and enzyme complexity.

F. Rottman, J. Bokar, P. Narayan, 1994, Biochimie.

Accurate and efficient N-6-adenosine methylation in spliceosomal U6 small nuclear RNA by HeLa cell extract in vitro

Ram Reddy, Shigeki Shimba, Joseph A. Bokar, 1995, Nucleic Acids Res..

Sunitinib and bevacizumab in advanced solid tumors: A phase I trial

B. Rini, T. Mekhail, R. Bukowski, 2008 .

A phase I study of rebeccamycin analog in combination with oxaliplatin in patients with refractory solid tumors

M. Cooney, A. Dowlati, S. Remick, 2011, Investigational New Drugs.

Pharmacokinetic profile of the base-excision repair inhibitor methoxyamine-HCl (TRC102; MX) given as an one-hour intravenous infusion with temozolomide (TMZ) in the first-in-human phase I clinical trial.

Lili Liu, A. Dowlati, S. Gerson, 2010 .

Phase I trial of docetaxel given every 3 weeks and daily lenalidomide in patients with advanced solid tumors

M. Cooney, A. Dowlati, S. Remick, 2009, Investigational New Drugs.

Phase I trial of sunitinib and gemcitabine in patients with advanced solid tumors

M. Cooney, A. Dowlati, N. Meropol, 2012, Cancer Chemotherapy and Pharmacology.

Phase II trial of sorafenib (bay 43-9006) in patients with advanced anaplastic carcinoma of the thyroid (ATC).

P. Fu, M. Cooney, S. Remick, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase II trial of sorafenib (bay 43-9006) in patients with advanced anaplastic carcinoma of the thyroid (ATC).

M. Cooney, S. Remick, J. Bokar, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I study of the EGFR tyrosine kinase inhibitor erlotinib in combination with docetaxel and radiation in locally advanced squamous cell cancer of the head and neck (SCCHN).

A. Argiris, C. Hoppel, M. Cooney, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I trial of daily pomalidomide in patients with advanced solid tumors.

M. Cooney, R. Dreicer, A. Dowlati, 2010 .