R. Isbrucker

发表

Alternative methods and strategies to reduce, refine, and replace animal use for human vaccine post-licensing safety testing: state of the science and future directions

Robert H Levis, W. Casey, T. Finn, 2011 .

Report on the international workshop on alternatives to the murine histamine sensitization test (HIST) for acellular pertussis vaccines: state of the science and the path forward.

W. Stokes, W. Casey, L. Rinckel, 2014, Biologicals : journal of the International Association of Biological Standardization.

Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals.

R. Isbrucker, I. Ragan, Elliot Lilley, 2021, Biologicals : journal of the International Association of Biological Standardization.

Improving animal welfare and reducing animal use for human vaccine potency testing: state of the science and future directions

Robert H Levis, W. Casey, T. Finn, 2011 .

Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin.

G. Burdock, R. Isbrucker, RA Isbrucker, 2006, Regulatory toxicology and pharmacology : RTP.

In vitro effect of platelet-derived growth factor on fibroproliferation and effect of cytokine antagonists.

R. Isbrucker, M. L. Hooper, T. C. Peterson, 1994, Immunopharmacology.

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies.

R. Isbrucker, J. Bausch, A. Davidovich, 2006, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Pivotal Shigella Vaccine Efficacy Trials—Study Design Considerations from a Shigella Vaccine Trial Design Working Group

G. Kang, C. Deal, J. Platts-Mills, 2022, Vaccines.

Non-animal replacement methods for human vaccine potency testing: state of the science and future directions

W. Casey, T. Finn, R. Mcfarland, 2011, Procedia in Vaccinology.

Fibroproliferation in liver disease: Role of monocyte factors

R. Isbrucker, T. C. Peterson, 1992, Hepatology.

Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin.

S. Pomponi, R. Isbrucker, A. Wright, 2003, Biochemical pharmacology.

Structure-activity relationship studies of discodermolide and its semisynthetic acetylated analogs on microtubule function and cytotoxicity

R. Isbrucker, S. Gunasekera, R. Longley, 2001, Cancer Chemotherapy and Pharmacology.

Alternative Safety Testing Strategies for Acellular Pertussis Vaccines

R. Isbrucker, 2012 .

The inhibitory effect of ursodeoxycholic acid and pentoxifylline on platelet derived growth factor-stimulated proliferation is distinct from an effect by cyclic AMP.

R. Isbrucker, T. C. Peterson, G. Slysz, 1998, Immunopharmacology.

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: genotoxicity.

R. Isbrucker, J. Bausch, E. Wolz, 2006, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Adenosine mediates calcium-induced antinociception and potentiation of noradrenergic antinociception in the spinal cord

R. Isbrucker, J. Sawynok, A. Reid, 1990, Brain Research.

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 3: teratogenicity and reproductive toxicity studies in rats.

R. Isbrucker, J. Bausch, A. Davidovich, 2006, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Five new discodermolide analogues from the marine sponge Discodermia species.

G. K. Paul, S. Pomponi, R. Isbrucker, 2002, Journal of natural products.

Early Effects of Lasonolide A on Pancreatic Cancer Cells

R. Isbrucker, A. Wright, E. Guzmán, 2009, Journal of Pharmacology and Experimental Therapeutics.

Acetylator phenotyping: the urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity.

R. Isbrucker, K. Renton, C. T. Gillespie, 1994, Pharmacogenetics.

Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.

R. Isbrucker, D. Divlianska, A. Wright, 2011, Angewandte Chemie.

Assessment of arylamine N-acetyltransferase (NAT1) activity in mononuclear leukocytes of cystic fibrosis patients.

R. Isbrucker, K. Renton, C. T. Gillespie, 1995, British journal of clinical pharmacology.

Alternatives to HIST for acellular pertussis vaccines: progress and challenges in replacement.

J Arciniega, L Wagner, R Prymula, 2016, Pharmeuropa bio & scientific notes.