H. Grunert

发表

Internalization of human rhinovirus 14 into HeLa and ICAM-1-transfected BHK cells

H. Zeichhardt, H. Grunert, Kai-Uwe Wolf, 1997, Medical Microbiology and Immunology.

An assessment of the reproducibility of reverse transcription digital PCR quantification of HIV-1.

H. Zeichhardt, J. Huggett, A. Kummrow, 2021, Methods.

Replacement of a cis proline simplifies the mechanism of ribonuclease T1 folding.

U. Hahn, T. Kiefhaber, F. Schmid, 1990, Biochemistry.

The dangers of using Cq to quantify nucleic acid in biological samples; a lesson from COVID-19.

J. Vandesompele, H. Zeichhardt, C. Foy, 2021, Clinical chemistry.

His92Ala mutation in ribonuclease T1 induces segmental flexibility. An X-ray study.

U. Hahn, U. Heinemann, W. Saenger, 1992, Journal of molecular biology.

Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2'-adenylic acid.

W. Saenger, O. Landt, H. Grunert, 1991, European journal of biochemistry.

Studies on RNase T1 mutants affecting enzyme catalysis.

U. Hahn, W. Saenger, A. Zouni, 1991, European journal of biochemistry.

Rapid construction of adeno-associated virus vectors expressing multiple short hairpin RNAs with high antiviral activity against echovirus 30.

H. Zeichhardt, H. Fechner, J. Kurreck, 2010, Oligonucleotides.

Maintaining inhibition: siRNA double expression vectors against coxsackieviral RNAs.

V. Erdmann, H. Zeichhardt, S. Schubert, 2005, Journal of molecular biology.

Performance evaluation of 70 hepatitis B virus (HBV) surface antigen (HBsAg) assays from around the world by a geographically diverse panel with an array of HBV genotypes and HBsAg subtypes

H. Zeichhardt, S. Nick, H. Scheiblauer, 2010, Vox sanguinis.

Combination of soluble coxsackievirus-adenovirus receptor and anti-coxsackievirus siRNAs exerts synergistic antiviral activity against coxsackievirus B3.

V. Erdmann, H. Zeichhardt, S. Pinkert, 2009, Antiviral research.

Developing an effective RNA interference strategy against a plus-strand RNA virus: silencing of coxsackievirus B3 and its cognate coxsackievirus-adenovirus receptor

V. Erdmann, H. Zeichhardt, V. Lindig, 2005, Biological chemistry.

A general method for rapid site-directed mutagenesis using the polymerase chain reaction.

U. Hahn, O. Landt, H. Grunert, 1990, Gene.

RNA reference materials with defined viral RNA loads of SARS-CoV-2—A useful tool towards a better PCR assay harmonization

A. Berger, H. Zeichhardt, S. Ciesek, 2022, PloS one.

RNA cleaving '10-23' DNAzymes with enhanced stability and activity.

V. Erdmann, H. Zeichhardt, S. Schubert, 2003, Nucleic acids research.

Antiviral activity of highly potent siRNAs against echovirus 30 and its receptor.

V. Erdmann, H. Zeichhardt, D. Horbelt, 2009, Journal of virological methods.

The performance of human cytomegalovirus digital PCR Reference Measurement Procedure in seven External Quality Assessment schemes over four years.

H. Zeichhardt, Fran Van Heuverswyn, P. Corbisier, 2021, Methods.

Does proficiency testing improve the quality of hantavirus serodiagnostics? Experiences with INSTAND EQA schemes.

H. Zeichhardt, J. Hofmann, H. Grunert, 2015, International journal of medical microbiology : IJMM.

Gaining target access for deoxyribozymes.

V. Erdmann, H. Zeichhardt, S. Schubert, 2004, Journal of molecular biology.

Strand-specific silencing of a picornavirus by RNA interference: evidence for the superiority of plus-strand specific siRNAs.

V. Erdmann, H. Zeichhardt, S. Schubert, 2007, Antiviral research.

Folding of RNase T1 is decelerated by a specific tertiary contact in a folding intermediate

U. Hahn, T. Kiefhaber, F. Schmid, 1992, Proteins.

Indicator plates for rapid detection of ribonuclease T1 secreting Escherichia coli clones.

U. Hahn, O. Landt, H. Grunert, 1989, Nucleic acids research.

Expression of Ribonuclease T1 in Escherichia Coli and Rapid Purification of the Enzyme

M. Kimura, U. Hahn, H. Grunert, 1988 .

Drug-antibody conjugates with anti-HIV activity.

H. Zeichhardt, H. Grunert, M. Paulik, 1999, Biochemical pharmacology.

Crystal structure of ribonuclease T1 complexed with adenosine 2'-monophosphate at 1.8-A resolution.

W. Saenger, J. Ding, H. Grunert, 1993, The Journal of biological chemistry.

RNase T1 mutant Glu46Gln binds the inhibitors 2'GMP and 2'AMP at the 3' subsite.

U Heinemann, U. Hahn, U. Heinemann, 1992, Journal of molecular biology.

Ribonuclease T1 Is Active when Both Catalytic Histidines Are Replaced by Aspartate

U. Hahn, W. Saenger, O. Landt, 1997, Biological chemistry.

Application of small interfering RNAs modified by unlocked nucleic acid (UNA) to inhibit the heart‐pathogenic coxsackievirus B3

H. Zeichhardt, J. Wengel, J. Kurreck, 2010, FEBS letters.

Design of LNA‐modified siRNAs against the highly structured 5′ UTR of coxsackievirus B3

H. Zeichhardt, J. Wengel, J. Kurreck, 2008, FEBS letters.

Results of the first German external quality assessment scheme for the detection of monkeypox virus DNA

H. Zeichhardt, H. Rabenau, A. Nitsche, 2023, PloS one.

Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor

H. Zeichhardt, S. Pinkert, A. Dörner, 2007, Gene Therapy.

Digital PCR Method for Detection and Quantification of Specific Antimicrobial Drug-Resistance Mutations in Human Cytomegalovirus.

Alexandra Bogožalec Košir, H. Zeichhardt, M. Kammel, 2020, Journal of virological methods.

Treatment of coxsackievirus-B3-infected BALB/c mice with the soluble coxsackie adenovirus receptor CAR4/7 aggravates cardiac injury

H. Zeichhardt, V. Lindig, A. Dörner, 2006, Journal of Molecular Medicine.