I. Vliegen

发表

Selective inhibitors of picornavirus replication

E. De Clercq, J. Neyts, A. D. De Palma, 2008, Medicinal research reviews.

Hepatitis C virus-specific directly acting antiviral drugs.

R. De Francesco, L. Delang, J. Neyts, 2013, Current topics in microbiology and immunology.

Substituted imidazopyridines as potent inhibitors of HCV replication

William A. Lee, I. Shih, E. De Clercq, 2009, Journal of Hepatology.

Debio 025, a Cyclophilin Binding Molecule, Is Highly Efficient in Clearing Hepatitis C Virus (HCV) Replicon-Containing Cells When Used Alone or in Combination with Specifically Targeted Antiviral Therapy for HCV (STAT-C) Inhibitors

Jan Paeshuyse, Johan Neyts, J. Neyts, 2008, Antimicrobial Agents and Chemotherapy.

Mouse cytomegalovirus antigenic immune stimulation is sufficient to aggravate atherosclerosis in hypercholesterolemic mice.

I. Vliegen, C. Bruggeman, G. Grauls, 2005, Atherosclerosis.

Cytomegalovirus infection aggravates atherogenesis in apoE knockout mice by both local and systemic immune activation.

I. Vliegen, C. Bruggeman, G. Grauls, 2004, Microbes and infection.

CMV and Atherosclerosis

I. Vliegen, C. Bruggeman, F. Stassen, 2003 .

MCMV infection increases early T-lymphocyte influx in atherosclerotic lesions in apoE knockout mice.

I. Vliegen, Rien Blok, G. Grauls, 2002, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Chlamydophila pneumoniae (Chlamydia pneumoniae) accelerates the formation of complex atherosclerotic lesions in Apo E3-Leiden mice.

I. Vliegen, P. Kitslaar, C. Bruggeman, 2002, Cardiovascular research.

Hemin potentiates the anti-hepatitis C virus activity of the antimalarial drug artemisinin.

E. De Clercq, J. Neyts, I. Vliegen, 2006, Biochemical and biophysical research communications.

In vitro selection and characterization of HCV replicons resistant to multiple non-nucleoside polymerase inhibitors.

L. Delang, J. Neyts, I. Vliegen, 2012, Journal of hepatology.

Improved detection and quantification of mouse cytomegalovirus by real-time PCR.

I. Vliegen, C. Bruggeman, G. Grauls, 2003, Virus research.

Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase

William A. Lee, I. Shih, W. Zhong, 2011, Antimicrobial Agents and Chemotherapy.

Statins potentiate the in vitro anti‐hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development

F. Zoulim, L. Delang, J. Neyts, 2009, Hepatology.

Synthesis of new benzimidazole-coumarin conjugates as anti-hepatitis C virus agents.

E. De Clercq, J. Neyts, Asish R. Das, 2008, Antiviral research.

Coumarins hinged directly on benzimidazoles and their ribofuranosides to inhibit hepatitis C virus.

E. De Clercq, J. Neyts, F. Shieh, 2013, European journal of medicinal chemistry.

Cytomegalovirus as a possible risk factor for atherosclerosis : a study in the mouse

I. Vliegen, 2003 .

DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A

G. Lippens, R. Bartenschlager, A. Vandamme, 2010, PloS one.

In vitro Anti-hepatitis C Virus (HCV) Activities and Resistance Profile of Debio 025, A Non-immunosuppressive Cyclophilin Binding Molecule

J. Neyts, P. Gallay, I. Vliegen, 2009 .

88 PARTICULAR IN VITRO ANTI-HCV ACTIVITIES AND RESISTANCE PROFILE OF THE CYCLOPHILIN INHIBITOR DEBIO 025

J. Neyts, P. Gallay, I. Vliegen, 2009 .

Mechanistic characterization of GS-9190, a novel non-nucleoside inhibitor of HCV NS5B polymerase with potent antiviral activity and a unique mechanism of action

I. Shih, W. Zhong, W. Tse, 2007 .

GS-9190, a novel substituted imidazo-pyridine analogue, is a potent inhibitor of hepatitis C virus replication in vitro and remains active against known drug-resistant mutants

William A. Lee, I. Shih, W. Zhong, 2007 .

Comparative Study of the Genetic Barriers and Pathways towards Resistance of Selective Inhibitors of Hepatitis C Virus Replication

L. Delang, M. Froeyen, J. Neyts, 2011, Antimicrobial Agents and Chemotherapy.

Comparative In Vitro Anti-Hepatitis C Virus Activities of a Selected Series of Polymerase, Protease, and Helicase Inhibitors

P. Herdewijn, R. Bartenschlager, J. Neyts, 2008, Antimicrobial Agents and Chemotherapy.

In vitro combinations containing Tegobuvir are highly efficient in curing cells from HCV replicon and in delaying/preventing the development of drug resistance.

W. Zhong, J. Neyts, I. Vliegen, 2015, Antiviral research.

Selecting and characterizing drug-resistant hepatitis C virus replicon.

L. Delang, J. Neyts, I. Vliegen, 2013, Methods in molecular biology.

Rapid identification of bacteria by real-time amplification and sequencing of the 16S rRNA gene.

I. Vliegen, C. Bruggeman, C. Vink, 2006, Journal of microbiological methods.

Murine cytomegalovirus infection directs macrophage differentiation into a pro-inflammatory immune phenotype: implications for atherogenesis.

I. Vliegen, C. Bruggeman, F. Stassen, 2004, Microbes and infection.

Deletion of the vaccinia virus F13L gene results in a highly attenuated virus that mounts a protective immune response against subsequent vaccinia virus challenge.

R. Jordan, J. Neyts, I. Vliegen, 2012, Antiviral research.

Rational design of antiviral drug combinations based on equipotency using HCV subgenomic replicon as an in vitro model.

J. Neyts, I. Vliegen, J. Paeshuyse, 2018, Antiviral research.

Immune activation following cytomegalovirus infection: more important than direct viral effects in cardiovascular disease?

I. Vliegen, C. Bruggeman, F. Stassen, 2006, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Substituted Imidazopyridines as Potent Inhibitors of Hepatitis C Virus Replication that Target the Viral Polymerase

William A. Lee, W. Zhong, J. Neyts, 2007 .

The cyclophilin inhibitor Debio-025 is a potent inhibitor of hepatitis C virus replication in vitro with a unique resistance profile

R. Bartenschlager, R. Crabbé, B. Rosenwirth, 2006 .

The Twentieth International Conference on Antiviral Research

Debasish, Pierre, P. Herdewijn, 2007, Antiviral Research.