J. Irvin

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EFFECT OF POKEWEED ANTIVIRAL PROTEIN IN COMBINATION WITH GUANIDINE ON POLIOVIRUS MACROMOLECULAR SYNTHESIS

J. Irvin, 2006 .

Effective immunochemotherapy of CALLA+C mu+ human pre-B acute lymphoblastic leukemia in mice with severe combined immunodeficiency using B43 (anti-CD19) pokeweed antiviral protein immunotoxin plus cyclophosphamide.

Dorothea, F. Uckun, J. Irvin, 1992, Blood.

Production of a pokeweed antiviral protein (PAP)-containing immunotoxin, B43-PAP, directed against the CD19 human B lineage lymphoid differentiation antigen in highly purified form for human clinical trials.

J. Irvin, D. E. Myers, F. Uckun, 1991, Journal of immunological methods.

Purification and partial characterization of the antiviral protein from Phytolacca americana which inhibits eukaryotic protein synthesis.

J. Irvin, 1975, Archives of biochemistry and biophysics.

Pharmacokinetic features, immunogenicity, and toxicity of B43(anti-CD19)-pokeweed antiviral protein immunotoxin in cynomolgus monkeys.

W. Evans, N. Tumer, J. Irvin, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

In vivo toxicity, pharmacokinetics, and antileukemic activity of TXU (anti-CD7)-pokeweed antiviral protein immunotoxin.

W. Evans, W. Evans, F. Uckun, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

In vivo efficacy of B43 (anti-CD19)-pokeweed antiviral protein immunotoxin against BCL-1 murine B-cell leukemia

J. Irvin, L. Chelstrom, D. Finnegan, 1992 .

In vivo efficacy of B43 (anti-CD19)-pokeweed antiviral protein immunotoxin against BCL-1 murine B-cell leukemia.

F. Uckun, J. Irvin, L. Chelstrom, 1992, Blood.

Pokeweed antiviral protein: ribosome inactivation and therapeutic applications.

F. Uckun, J. Irvin, 1992, Pharmacology & therapeutics.

X‐ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs

I. Kurinov, F. Uckun, J. Irvin, 1999, Protein science : a publication of the Protein Society.

X-ray crystallographic analysis of pokeweed antiviral protein-II after reductive methylation of lysine residues.

I. Kurinov, F. Uckun, J. Irvin, 2000, Biochemical and biophysical research communications.

Treatment of human B-cell precursor leukemia in SCID mice using a combination of the investigational biotherapeutic agent B43-PAP with cytosine arabinoside.

W. Evans, J. Irvin, V. Avramis, 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

The distribution of 14C‐proline peptides synthesized in vitro directed by polycytidylic acid; the effect of chloramphenicol

J. Irvin, G. Julian, G. R. Julian, 1970, FEBS letters.

Anti-human immunodeficiency virus type 1 activity of an anti-CD4 immunoconjugate containing pokeweed antiviral protein

H. Balfour, J. Irvin, A. Erice, 1993, Antimicrobial Agents and Chemotherapy.

Binding of aminoacyl transfer ribonucleic acid synthetases to ribosomes from rabbit reticulocytes.

B. Hardesty, J. Irvin, 1972, Biochemistry.

Preliminary x-ray diffraction studies on an anti-viral protein.

A. Monzingo, J. Robertus, J. Irvin, 1977, Biochemical and biophysical research communications.

Purification and properties of a second antiviral protein from Phytolacca americana which inactivates eukaryotic ribosomes.

J. Robertus, J. Irvin, T. Kelly, 1980, Archives of biochemistry and biophysics.

Pokeweed antiviral protein isoforms PAP-I, PAP-II, and PAP-III depurinate RNA of human immunodeficiency virus (HIV)-1.

F. Uckun, J. Irvin, T. Venkatachalam, 1999, Biochemical and biophysical research communications.

Pokeweed antiviral protein inactivates pokeweed ribosomes; implications for the antiviral mechanism.

J. Irvin, T. Mabry, M. Ready, 1994, The Plant journal : for cell and molecular biology.

Purification and partial characterization of another form of the antiviral protein from the seeds of Phytolacca americana L. (pokeweed).

L. Barbieri, F. Stirpe, J. Irvin, 1982, The Biochemical journal.

Inhibition of herpes simplex virus DNA synthesis by pokeweed antiviral protein

J. Irvin, G. M. Aron, G. Teltow, 1983, Antimicrobial Agents and Chemotherapy.

The effect of an antiviral peptide on the ribosomal reactions of the peptide elongation enzymes, EF-I and EF-II.

B. Hardesty, T. Obrig, J. Irvin, 1973, Archives of biochemistry and biophysics.

TXU (Anti-CD7)-Pokeweed Antiviral Protein as a Potent Inhibitor of Human Immunodeficiency Virus

F. Uckun, J. Irvin, L. Chelstrom, 1998, Antimicrobial Agents and Chemotherapy.

Inhibition of herpes simplex virus multiplication by the pokeweed antiviral protein

J. Irvin, G. M. Aron, 1980, Antimicrobial Agents and Chemotherapy.

In vitro and in vivo antileukemic activity of B43-pokeweed antiviral protein against radiation-resistant human B-cell precursor leukemia cells.

N. Tumer, J. Irvin, L. Chelstrom, 1995, Blood.

MONOCLONAL ANTIBODY TO TUMOR SPECIFIC EPITOPE OF MURINE LYMPHOMA CELLS: USE IN CHARACTERIZATION OF ANTIGEN AND IN IMMUNOTHERAPY

J. Allison, J. Irvin, B. McIntyre, 1983 .

Inhibition of peptide initiation on reticulocyte ribosomes by edeine.

B. Hardesty, T. Obrig, W. Culp, 1971, European journal of biochemistry.

Reversal of the inhibitory effects of the pokeweed antiviral protein upon protein synthesis.

J. Irvin, T. L. Rodes, Thomas L. Rodes, 1981, Biochimica et biophysica acta.

Depurination of plant ribosomes by pokeweed antiviral protein

J. Irvin, B. E. Taylor, 1990, FEBS letters.

Pokeweed antiviral protein.

J. Irvin, 1983, Pharmacology & therapeutics.

INHIBITION OF POLIOVIRUS REPLICATION BY A PLANT ANTIVIRAL PEPTIDE *

B. Hardesty, J. Irvin, M. Ussery, 1977, Annals of the New York Academy of Sciences.

Enzymatic inactivation of eukaryotic ribosomes by the pokeweed antiviral protein

J. Irvin, J. Dallal, 1978, FEBS letters.

The 2.5 A structure of pokeweed antiviral protein.

A. Monzingo, J. Robertus, J. Irvin, 1993, Journal of molecular biology.

Inhibition of elongation factor 2-dependent translocation by the pokeweed antiviral protein and ricin.

J. Irvin, S. Gessner, 1980, The Journal of biological chemistry.

Effects of the intermolecular toxin-monoclonal antibody linkage on the in vivo stability, immunogenicity and anti-leukemic activity of B43 (anti-CD19) pokeweed antiviral protein immunotoxin.

F. Uckun, J. Irvin, L. Chelstrom, 1993, Leukemia & lymphoma.

Chemical modifications of Pokeweed antiviral protein: effects upon ribosome inactivation, antiviral activity and cytotoxicity

J. Irvin, Gary M. Aron, 1982, FEBS letters.

Poliovirus-mediated entry of pokeweed antiviral protein

J. Irvin, M. Shearer, G. M. Aron, 1990, Antimicrobial Agents and Chemotherapy.

In vivo efficacy of B43 (anti-CD19)-pokeweed antiviral protein immunotoxin against human pre-B cell acute lymphoblastic leukemia in mice with severe combined immunodeficiency.

D. Arthur, F. Uckun, J. Irvin, 1992, Blood.

The effect of sodium fluoride, edeine, and cycloheximide on peptide synthesis with reticulocyte ribosomes.

B. Hardesty, T. Obrig, W. Culp, 1973, Basic life sciences.

Purification and characterization of three elongation factors, EF-1 alpha, EF-1 beta gamma, and EF-2, from wheat germ.

J. Irvin, J. Ravel, E. Burks, 1984, The Journal of biological chemistry.

In vivo anti-leukemic efficacy of anti-CD7-pokeweed antiviral protein immunotoxin against human T-lineage acute lymphoblastic leukemia/lymphoma in mice with severe combined immunodeficiency.

J. Irvin, L. Chelstrom, D. Finnegan, 1993, Leukemia.

The nature of the differential inhibition of polyphenylalanine synthesis in extracts from Artemia salina and rabbit reticulocytes by the Phytolacca americana protein

J. P. Suits, J. Irvin, 1976, Molecular Biology Reports.

Favorable pharmacodynamic features and superior anti-leukemic activity of B43 (anti-CD19) immunotoxins containing two pokeweed antiviral protein molecules covalently linked to each monoclonal antibody molecule.

W. Evans, J. Irvin, D. E. Myers, 1995, Leukemia & lymphoma.