T. Peters

发表

Hepatitis A virus proteinase 3C binding to viral RNA: correlation with substrate binding and enzyme dimerization.

C. Rademacher, Y. Kusov, V. Gauss-Müller, 2005, The Biochemical journal.

Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase

Karina Persson, W. Wakarchuk, G. Widmalm, 2012, Glycoconjugate Journal.

Glycan-Induced Protein Dynamics in Human Norovirus P Dimers Depend on Virus Strain and Deamidation Status

E. Marklund, C. Caleman, C. Uetrecht, 2020, bioRxiv.

NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors.

Thomas Peters, Bernd Meyer, B. Meyer, 2003, Angewandte Chemie.

A Matter of Order: How E‐Selectin Makes Sweet Contacts

T. Peters, 2012, Chembiochem : a European journal of chemical biology.

Characterization of Ligand Binding to the Bifunctional Key Enzyme in the Sialic Acid Biosynthesis by NMR

W. Reutter, A. J. Benie, T. Peters, 2004, Journal of Biological Chemistry.

A rigid lanthanide binding tag to aid NMR studies of a 70 kDa homodimeric coat protein of human norovirus.

G. Domínguez, Alvaro Mallagaray, T. Peters, 2016, Chemical communications.

Attachment of norovirus to histo blood group antigens: a cooperative multistep process.

C. Uetrecht, Alvaro Mallagaray, T. Peters, 2015, Angewandte Chemie.

Targeting norovirus infection-multivalent entry inhibitor design based on NMR experiments.

C. Rademacher, T. Peters, P. Kitov, 2011, Chemistry.

NMR-based exploration of the acceptor binding site of human blood group B galactosyltransferase with molecular fragments

M. Palcic, G. Widmalm, C. Rademacher, 2010, Glycoconjugate Journal.

Application of 3D‐TOCSY‐trNOESY for the Assignment of Bioactive Ligands from Mixtures

T. Peters, L. Herfurth, T. Weimar, 2000 .

Assignment of Ala, Ile, LeuproS, Met, and ValproS methyl groups of the protruding domain of murine norovirus capsid protein VP1 using methyl–methyl NOEs, site directed mutagenesis, and pseudocontact shifts

C. Uetrecht, Alvaro Mallagaray, T. Peters, 2022, Biomolecular NMR Assignments.

Norovirus, glycans and attachment.

Alvaro Mallagaray, T. Peters, S. Taube, 2018, Current opinion in virology.

Human norovirus GII.4(MI001) P dimer binds fucosylated and sialylated carbohydrates

C. Uetrecht, Alvaro Mallagaray, T. Peters, 2017, Glycobiology.

Epitope mapping of histo blood group antigens bound to norovirus VLPs using STD NMR experiments reveals fine details of molecular recognition

T. Lowary, T. Peters, M. Leuthold, 2017, Glycoconjugate Journal.

"Double-click" protocol for synthesis of heterobifunctional multivalent ligands: toward a focused library of specific norovirus inhibitors.

T. Peters, P. Kitov, D. Bundle, 2011, Chemistry.

Chemical‐Shift Perturbations Reflect Bile Acid Binding to Norovirus Coat Protein: Recognition Comes in Different Flavors

Alvaro Mallagaray, M. Stein, T. Peters, 2019, Chembiochem : a European journal of chemical biology.

Donor substrate binding to trans-sialidase of Trypanosoma cruzi as studied by STD NMR.

T. Peters, J. Thiem, A. Blume, 2007, Carbohydrate research.

Assessing glycosidic linkage flexibility: Conformational analysis of the repeating trisaccharide unit of Aeromonas salmonicida

T. Peters, T. Weimar, 1994, Journal of biomolecular NMR.

Mapping the binding of synthetic disaccharides representing epitopes of chlamydial lipopolysaccharide to antibodies with NMR.

H. Brade, L. Brade, T. Peters, 2000, Biochemistry.

Combined NMR, grid search/MM3 and Metropolis Monte Carlo/GEGOP studies of two l-fucose containing disaccharides: α-l-Fuc-(1,4)-β-d-GlcNAc-OMe and α-l-Fuc-(1,6)-β-d-GlcNAc-OMe

A. Imberty, S. Pérez, T. Peters, 1997 .

Conformational analysis of key disaccharide components of Brucella A and M antigens

J. Brisson, T. Peters, D. Bundle, 1990 .

Conformational analysis of a disaccharide fragment of the polysaccharide antigen of Streptococcus pneumoniae type 1 using n.m.r. spectroscopy and HSEA calculations.

T. Peters, K. Bock, H. Lönn, 1990, Carbohydrate research.

Assaying Sialyltransferase Activity with Surface Plasmon Resonance

Thomas Peters, Hannelore Peters, T. Peters, 2006, Chembiochem : a European journal of chemical biology.

Conformational analysis of α-d-Fuc-(1→4)-β-d-GlcNAc-OMe. One-dimensional transient NOE experiments and metropolis Monte Carlo simulations

B. Meyer, T. Peters, T. Weimar, 1993 .

Specificity of ligand binding to yeast hexokinase PII studied by STD-NMR.

A. J. Benie, T. Peters, Michael Fitzen, 2009, Carbohydrate research.

Saturation transfer difference NMR and computational modeling of a sialoadhesin-sialyl lactose complex.

S. Kelm, A. Bhunia, V. Jayalakshmi, 2004, Carbohydrate research.

Protein NMR Studies of Substrate Binding to Human Blood Group A and B Glycosyltransferases

M. Palcic, T. Peters, L. L. Grimm, 2017, Chembiochem : a European journal of chemical biology.

Thermodynamic signature of substrates and substrate analogs binding to human blood group B galactosyltransferase from isothermal titration calorimetry experiments.

M. Palcic, T. Peters, E. Muñoz, 2013, Biopolymers.

A nonionic inhibitor with high specificity for the UDP-Gal donor binding site of human blood group B galactosyltransferase: design, synthesis, and characterization.

B. Meyer, T. Hackl, M. Palcic, 2013, Journal of medicinal chemistry.

A New Concept for Glycosyltransferase Inhibitors: Nonionic Mimics of the Nucleotide Donor of the Human Blood Group B Galactosyltransferase

B. Meyer, T. Peters, K. Schaefer, 2012, Chembiochem : a European journal of chemical biology.

A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus

T. Stehle, W. Atwood, U. Neu, 2013, PLoS pathogens.

Insights into neuronal cell metabolism using NMR spectroscopy: uridyl diphosphate N-acetyl-glucosamine as a unique metabolic marker.

L. Pellerin, T. Peters, A. Gallinger, 2011, Angewandte Chemie.

Aleuria aurantia Agglutinin Recognizes Multiple Conformations of α‐L‐Fuc‐(1→6)‐β‐D‐GlcNAc‐OMe

T. Peters, T. Weimar, 1994 .

NMR Experiments Shed New Light on Glycan Recognition by Human and Murine Norovirus Capsid Proteins

Alvaro Mallagaray, Hannelore Peters, T. Peters, 2021, Viruses.

Conformational analysis of synthetic heparin-like oligosaccharides containing α-L-idopyranosyluronic acid†

T. Peters, A. Pollex, C. V. Boeckel, 1987 .

NMR Experiments Provide Insights into Ligand-Binding to the SARS-CoV-2 Spike Protein Receptor-Binding Domain.

C. Uetrecht, T. Peters, N. Tautz, 2022, Journal of the American Chemical Society.

Protein Secondary Structure Affects Glycan Clustering in Native Mass Spectrometry

K. Pagel, C. Uetrecht, Alvaro Mallagaray, 2021, bioRxiv.

Application of homonuclear 3D NMR experiments and 1D analogs to study the conformation of sialyl Lewisx bound to E-selectin

J. Brisson, B. Ernst, R. Weisemann, 1997, Journal of biomolecular NMR.

Improved synthesis of α‐L‐Fuc(1→4)‐β‐D‐GlcNAc and α‐L‐Fuc(1→6)‐β‐D‐GlcNAc building blocks: A convergent strategy employing 4‐O→6‐O acetyl migration; NOE data of the protected α‐1,4‐linked disaccharide

T. Peters, T. Weimar, 1991 .

Fucose-Functionalized Precision Glycomacromolecules Targeting Human Norovirus Capsid Protein.

C. Uetrecht, S. Schmidt, L. Hartmann, 2018, Biomacromolecules.

Conformational analysis of a Chlamydia-specific disaccharide α-Kdo-(2→8)-α-Kdo-(2→O)-allyl in aqueous solution and bound to a monoclonal antibody: Observation of intermolecular transfer NOEs

H. Brade, L. Brade, T. Haselhorst, 1998 .

Conformational analysis of a Chlamydia-specific disaccharide alpha-Kdo-(2-->8)-alpha-Kdo-(2-->O)-allyl in aqueous solution and bound to a monoclonal antibody: observation of intermolecular transfer NOEs.

H. Brade, L. Brade, T. Haselhorst, 1998, Journal of biomolecular NMR.

Definition of Brucella A and M epitopes by monoclonal typing reagents and synthetic oligosaccharides

P. Meikle, M. Perry, T. Peters, 1989, Infection and immunity.

Attachment of norovirus to histo blood group antigens: a cooperative multistep process.

C. Uetrecht, Alvaro Mallagaray, T. Peters, 2015, Angewandte Chemie.

The αGal Epitope of the Histo-Blood Group Antigen Family Is a Ligand for Bovine Norovirus Newbury2 Expected to Prevent Cross-Species Transmission

N. Bovin, J. Le Pendu, A. Charpilienne, 2009, PLoS pathogens.

Neutralization of a common cold virus by concatemers of the third ligand binding module of the VLDL-receptor strongly depends on the number of modules.

J. Angulo, D. Blaas, Hannelore Peters, 2005, Virology.

Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions

T. Smith, C. Uetrecht, C. Waudby, 2022, Communications Biology.

Epitope mapping of sialyl Lewis(x) bound to E-selectin using saturation transfer difference NMR experiments.

B. Ernst, A. J. Benie, T. Peters, 2003, Glycobiology.

Conformational analysis of biantennary glycans and molecular modeling of their complexes with lentil lectin.

A. Imberty, S. Pérez, A. Imberty, 1997, Journal of molecular graphics & modelling.

Conformational Analysis of Synthetic Heparin-like Oligosaccharides Containing α-L-Idopyranosyluronic Acid.

T. Peters, A. Pollex, C. V. Boeckel, 1987 .

Conformational analysis of a complex between Dolichos biflorus lectin and the Forssman pentasaccharide using transferred NOE build-up curves

E. Mikros, T. Peters, M. Rinnbauer, 1998 .

Synthesis and conformational analysis of methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside

T. Peters, 1991 .

Glycans Controlling Virus Infections: Meeting Report on the 1st International Symposium on Glycovirology Schöntal, Germany, 02⁻04 May 2018.

Mario Schelhaas, T. Stehle, T. Peters, 2018 .

Glycans Controlling Virus Infections: Meeting Report on the 1st International Symposium on Glycovirology Schöntal, Germany, 02–04 May 2018

Mario Schelhaas, T. Stehle, T. Peters, 2018, Viruses.

Fragment Growing to Design Optimized Inhibitors for Human Blood Group B Galactosyltransferase (GTB)

Thomas Hackl, Thomas Peters, Bernd Meyer, 2019, ChemMedChem.

Transferred nuclear Overhauser enhancement (NOE) and rotating-frame NOE experiments reflect the size of the bound segment of the Forssman pentasaccharide in the binding site of Dolichos biflorus lectin.

M. Etzler, S. Pérez, F. Casset, 1997, European journal of biochemistry.

Determination of the Bioactive Conformation of the Carbohydrate Ligand in the E‐Selectin/Sialyl LewisX Complex

Thomas Peters, Beat Ernst, B. Ernst, 1995 .

Murine norovirus capsid plasticity – Glycochenodeoxycholic acid stabilizes P-domain dimers and triggers escape from antibody recognition

T. Smith, C. Uetrecht, Alvaro Mallagaray, 2021, bioRxiv.

Structure and dynamics of oligosaccharides: NMR and modeling studies.

B. M. Pinto, T. Peters, T Peters, 1996, Current opinion in structural biology.

Synthesis of antigenic determinants of the Brucella A antigen, utilizing methyl 4-azido-4,6-dideoxy-alpha-D-mannopyranoside efficiently derived from D-mannose.

T. Peters, D. Bundle, M. Gerken, 1988, Carbohydrate research.

High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release

M. Palcic, T. Peters, S. V. Evans, 2017, Glycobiology.

Binding of an acceptor substrate analog enhances the enzymatic activity of human blood group B galactosyltransferase.

M. Palcic, Hannelore Peters, T. Peters, 2010, Glycobiology.

Synthetic antigenic determinants of the Brucella A polysaccharide: A disaccharide thioglycoside for block synthesis of pentasaccharide and lower homologues of α1,2-linked 4,6-dideoxy-4-formamido-α-D-mannose

T. Peters, D. Bundle, 1989 .

Block synthesis of two pentasaccharide determinants of the Brucella M antigen using thioglycoside methodologies

T. Peters, D. Bundle, 1989 .

Synthesis of 4,6-dideoxy-4-formamido-α-D-mannose containing tri-, tetra-, and penta-saccharides, antigenic determinants of the Brucella A and M antigens

T. Peters, D. Bundle, 1987 .

Insights into Allosteric Control of Human Blood Group A and B Glycosyltransferases from Dynamic NMR

T. Peters, Friedemann Flügge, 2019, ChemistryOpen.

Substrate Binding Drives Active‐Site Closing of Human Blood Group B Galactosyltransferase as Revealed by Hot‐Spot Labeling and NMR Spectroscopy Experiments

T. Peters, S. Weissbach, Friedemann Flügge, 2018, Chembiochem : a European journal of chemical biology.

Complete assignment of Ala, Ile, Leu, Met and Val methyl groups of human blood group A and B glycosyltransferases using lanthanide-induced pseudocontact shifts and methyl–methyl NOESY

T. Peters, Friedemann Flügge, 2018, Journal of biomolecular NMR.

Complete assignment of Ala, Ile, Leu, Met and Val methyl groups of human blood group A and B glycosyltransferases using lanthanide-induced pseudocontact shifts and methyl–methyl NOESY

T. Peters, Friedemann Flügge, 2018, Journal of Biomolecular NMR.

NMR spectroscopy of glycoconjugates

Jesús Jiménez-Barbero, Thomas Peters, T. Peters, 2002 .

Block Synthesis of Two Pentasaccharide Determinants of the Brucella M Antigen Using Thioglycoside Methodologies.

T. Peters, D. Bundle, 1989 .

Conformational analysis of blood group A trisaccharide in solution and in the binding site of Dolichos biflorus lectin using transient and transferred nuclear Overhauser enhancement (NOE) and rotating-frame NOE experiments.

M. Etzler, S. Pérez, E. Korchagina, 1996, European journal of biochemistry.

Epitope mapping of the O-chain polysaccharide of Legionella pneumophila serogroup 1 lipopolysaccharide by saturation-transfer-difference NMR spectroscopy.

Thomas Peters, Matthias Frosch, U. Zähringer, 2002, European journal of biochemistry.

Synthesis and conformational and NMR studies of α-d-mannopyranosyl and α-d-mannopyranosyl-(1 → 2)-α-d-mannopyranosyl linked to l-serine and l-threonine

J. Brisson, L. Kenne, T. Peters, 1992 .

Synthesis and conformational and NMR studies of α-D-mannopyranosyl-(1→2)-α-D-mannopyranosyl linked to L-serine and L-threonine

J. Brisson, L. Kenne, T. Peters, 1992 .

Molecular Recognition of UDP-Gal by β-1,4-Galactosyltransferase T1.

T. Peters, Thorsten Biet, 2001, Angewandte Chemie.

Ligand specificity of CS-35, a monoclonal antibody that recognizes mycobacterial lipoarabinomannan: a model system for oligofuranoside-protein recognition.

D. Schriemer, C. Rademacher, Hashem A. Taha, 2007, Journal of the American Chemical Society.

Blood group B galactosyltransferase: insights into substrate binding from NMR experiments.

B. Meyer, J. Angulo, N. Krishna, 2006, Journal of the American Chemical Society.

3.35 – The Use of NMR Spectroscopy in Carbohydrate–Protein Molecular Interactions

T. Peters, 2007 .

Fragment-based Screening of the Donor Substrate Specificity of Human Blood Group B Galactosyltransferase Using Saturation Transfer Difference NMR*

J. Angulo, M. Palcic, Hannelore Peters, 2006, Journal of Biological Chemistry.

Virus-ligand interactions: identification and characterization of ligand binding by NMR spectroscopy.

D. Blaas, A. J. Benie, Englbert Bäuml, 2003, Journal of the American Chemical Society.

Molecular recognition of ligands by native viruses and virus-like particles as studied by NMR experiments.

C. Rademacher, T. Peters, 2008, Topics in current chemistry.

Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection

R. Garcea, T. Stehle, M. Gilbert, 2012, PLoS pathogens.

Molecular recognition of sialyl Lewis(x) and related saccharides by two lectins.

T. Haselhorst, T. Peters, T Weimar, 2001, Journal of the American Chemical Society.

A glycosyltransferase inhibitor from a molecular fragment library simultaneously interferes with metal ion and substrate binding.

M. Palcic, T. Peters, R. Jørgensen, 2012, Angewandte Chemie.

Spin ballet for sweet encounters: saturation-transfer difference NMR and X-ray crystallography complement each other in the elucidation of protein–glycan interactions

T. Stehle, U. Neu, T. Peters, 2018, Acta crystallographica. Section F, Structural biology communications.

Molecular details of the recognition of blood group antigens by a human norovirus as determined by STD NMR spectroscopy.

C. Rademacher, T. Peters, P. Kitov, 2012, Angewandte Chemie.

Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide

Shibo Jiang, Thomas Peters, Bernd Meyer, 2007, Cell.

Consistent Bioactive Conformation of the Neu5Acα(2→3)Gal Epitope Upon Lectin Binding

O. Schwardt, B. Ernst, A. Bhunia, 2008, Chembiochem : a European journal of chemical biology.

NMR analysis of carbohydrate-protein interactions.

Thomas Peters, Francisco Parra, J. Angulo, 2006, Methods in enzymology.

NMR experiments reveal the molecular basis of receptor recognition by a calicivirus.

N. Krishna, M. Palcic, C. Rademacher, 2008, Journal of the American Chemical Society.

A Monte Carlo method for conformational analysis of saccharides.

J. Brisson, B. Meyer, R. Somorjai, 1993, Carbohydrate research.

NMR experiments reveal distinct antibody-bound conformations of a synthetic disaccharide representing a general structural element of bacterial lipopolysaccharide epitopes.

H. Brade, L. Brade, T. Haselhorst, 1999, Biochemistry.

TR‐NOE Experiments to Study Carbohydrate‐Protein Interactions

T. Peters, J. Jiménez‐Barbero, 2003 .

Functional binding of hexanucleotides to 3C protease of hepatitis A virus

G. Sczakiel, W. Wünsche, Y. Kusov, 2011, Nucleic acids research.

Epitope mapping of histo blood group antigens bound to norovirus VLPs using STD NMR experiments reveals fine details of molecular recognition

T. Lowary, T. Peters, M. Leuthold, 2017, Glycoconjugate Journal.

Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase

Karina Persson, W. Wakarchuk, G. Widmalm, 2012, Glycoconjugate Journal.

STD‐NMR experiments identify a structural motif with novel second‐site activity against West Nile virus NS2B‐NS3 protease

R. Hilgenfeld, Linlin Zhang, T. Peters, 2017, Antiviral research.

Saturation transfer difference nuclear magnetic resonance titrations reveal complex multistep-binding of L-fucose to norovirus particles

C. Rademacher, Alvaro Mallagaray, T. Peters, 2016, Glycobiology.

Norovirus–glycan interactions — how strong are they really?

C. Uetrecht, Alvaro Mallagaray, T. Peters, 2021, Biochemical Society transactions.

A post-translational modification of human Norovirus capsid protein attenuates glycan binding

T. Stehle, C. Uetrecht, K. Rand, 2019, Nature Communications.

Bioaffinity NMR Spectroscopy: Identification of an E‐Selectin Antagonist in a Substance Mixture by Transfer NOE

Thomas Peters, Beat Ernst, Bernd Meyer, 1999 .

Characterization of ligand binding to N-acetylglucosamine kinase studied by STD NMR.

A. J. Benie, T. Peters, M. Berger, 2008, Biochemistry.

Bioactive Conformation I

T. Peters, 2008 .

Screening mixtures for biological activity by NMR.

B. Meyer, T. Peters, B Meyer, 1997, European journal of biochemistry.

NMR Methods for Screening the Binding of Ligands to Proteins — Identification and Characterization of Bioactive Ligands

T. Peters, L. Herfurth, Thorsten Biet, 2002 .

Consistent Bioactive Conformation of the Neu5Acα(2→3)Gal Epitope Upon Lectin Binding

O. Schwardt, B. Ernst, A. Bhunia, 2008, Chembiochem : a European journal of chemical biology.

A Monte Carlo method for conformational analysis of saccharides.

J. Brisson, B. Meyer, R. Somorjai, 1993, Carbohydrate Research.

Improved Synthesis of α‐L‐Fuc(1 → 4)‐β‐D‐GlcNAc (‐)‐( III) and α‐L‐Fuc(1 → 6)‐β‐D‐GlcNAc (‐)‐(I) Building Blocks: A Convergent Strategy Employing 4‐O → 6‐O Acetyl Migration. NOE Data of the Protected α‐1,4‐Linked Disaccharide.

T. Peters, T. Weimar, 1991 .