H. Levy

发表

Use of the Guthrie bacterial inhibition assay to monitor blood phenylalanine for dietary treatment of phenylketonuria

E. Allred, F. Rohr, Melissa Turner, 1996 .

The BabySeq project: implementing genomic sequencing in newborns

R. Green, H. Rehm, S. Waisbren, 2018, BMC Pediatrics.

Methionine adenosyltransferase I/III deficiency: novel mutations and clinical variations.

J. Chou, H. Levy, M. Chamberlin, 2000, American journal of human genetics.

A psychosocial model of a medical problem: Maternal phenylketonuria

S. Waisbren, S. Shiloh, H. Levy, 1989, Journal of Primary Prevention.

Newborn screening of lysosomal storage disorders.

H. Levy, D. Marsden, 2010, Clinical chemistry.

Expansion and Implications of Newborn Screening

H. Levy, F. Rajabi, Farrah Rajabi, 2015, Current Genetic Medicine Reports.

Galactose-1-phosphate uridyl transferase deficiency due to Duarte/galactosemia combined variation: clinical and biochemical studies.

D. Walton, E. Beutler, H. Levy, 1978, The Journal of pediatrics.

Histidase and histidinemia. Clinical and molecular considerations.

R. Mcinnes, R. Taylor, H. Levy, 1991, Molecular biology & medicine.

Sepsis due to Escherichia coli in neonates with galactosemia.

G. Vawter, J. Klein, H. Levy, 1977, The New England journal of medicine.

Phenotypic variability in deficiency of the α subunit of succinate‐CoA ligase

S. Waisbren, D. Harris, P. Arn, 2019, JIMD reports.

Phenotyping and treatment of phenylketonuria – Authors' reply

N. Blau, H. Levy, F. Spronsen, 2011, The Lancet.

Mutations in the phenylalanine hydroxylase gene identified in 95 patients with phenylketonuria using novel systems of mutation scanning and specific genotyping based upon thermal melt profiles.

S. Dobrowolski, R. Martin, R. Koch, 2007, Molecular genetics and metabolism.

Efficacy of sapropterin dihydrochloride (tetrahydrobiopterin, 6R-BH4) for reduction of phenylalanine concentration in patients with phenylketonuria: a phase III randomised placebo-controlled study

A. Chakrapani, H. Levy, C. Whitley, 2007, The Lancet.

Phenylketonuria

N. Blau, H. Levy, F. Spronsen, 1961, The Lancet.

Phenylalanine hydroxylase gene mutations in the United States: report from the Maternal PKU Collaborative Study.

R. Matalon, P. Guldberg, R. Koch, 1996, American journal of human genetics.

Discontinuation of Pegvaliase therapy during maternal PKU pregnancy and postnatal breastfeeding: A case report

C. Harding, F. Rohr, H. Levy, 2020, Molecular genetics and metabolism reports.

U.S. newborn screening system guidelines: Statement of the council of regional networks for genetic services

E. McCabe, W. H. Hannon, A. Davidson, 1992 .

Prevalence of comorbid conditions among adult patients diagnosed with phenylketonuria.

S. Waisbren, S. Cederbaum, B. Burton, 2018, Molecular genetics and metabolism.

A study of cardiovascular risk in heterozygotes for homocystinuria.

R. Havlik, M. Feinleib, V. McKusick, 1981, American journal of human genetics.

Expanded screening of newborns for genetic disorders.

S. Waisbren, H. Levy, 2004, JAMA.

Genomics in newborn screening.

H. Levy, U. Lichter-Konecki, Y. Landau, 2014, The Journal of pediatrics.

Intelligence and personality characteristics in adults with untreated atypical phenylketonuria and mild hyperphenylalaninemia.

S. Waisbren, H. Levy, R. Schnell, 1984, The Journal of pediatrics.

Effects of Untreated Maternal Phenylketonuria and Hyperphenylalaninemia on the Fetus

S. Waisbren, H. Levy, 1983 .

Phenylalanine hydroxylase genotype-phenotype associations in the United States: A single center study.

P. Guldberg, S. Dobrowolski, F. Güttler, 2019, Molecular genetics and metabolism.

Newborn screening for metabolic disorders.

H. Levy, D. Marsden, C. Larson, 2006, The Journal of pediatrics.

Chapter 27 – Newborn Screening

H. Levy, S. Albers, 2005 .

Psychosocial factors in maternal phenylketonuria: women's adherence to medical recommendations.

S. Waisbren, S. Shiloh, H. Levy, 1995, American journal of public health.

Confounding factors in identification of disease-resilient individuals

H. Levy, D. Watkins, D. Rosenblatt, 2016, Nature Biotechnology.

Lessons from the past--looking to the future. Newborn screening.

H. Levy, 2003, Pediatric annals.

Fetal Fatty Acid Oxidation Defects and Maternal Liver Disease in Pregnancy

L. Wilkins-Haug, H. Levy, C. Larson, 2006, Obstetrics and gynecology.

Amino Acids and Inherited Amino Acid-Related Disorders

F. Rohr, H. Levy, D. Ney, 2018 .

Characterization of a novel biochemical abnormality in galactosemia: deficiency of glycolipids containing galactose or N-acetylgalactosamine and accumulation of precursors in brain and lymphocytes.

S. Hakomori, J. Reichardt, H. Eisen, 1991, Biochemical medicine and metabolic biology.

The adult galactosemic phenotype

R. Green, S. Waisbren, C. Gordon, 2012, Journal of Inherited Metabolic Disease.

The ability of an LC-MS/MS-based erythrocyte GALT enzyme assay to predict the phenotype in subjects with GALT deficiency.

S. Waisbren, G. Berry, H. Levy, 2019, Molecular genetics and metabolism.

Speech and language deficits in early-treated children with galactosemia.

S. Waisbren, H. Levy, R. Schnell, 1983, The Journal of pediatrics.

Late onset of distinct neurologic syndromes in galactosemic siblings

J. Friedman, H. Levy, R. Boustany, 1989, Neurology.

Methionine transamination in patients with homocystinuria due to cystathionine beta-synthase deficiency.

G. Boers, H. Levy, A. Tangerman, 2000, Metabolism: clinical and experimental.

Maternal histidinaemia: Pregnancies and offspring outcomes

S. Waisbren, H. Levy, J. J. Yu, 2004, Journal of Inherited Metabolic Disease.

CURRENT CONCEPTS OF TREATMENT IN PHENYLKETONURIA

H. Levy, E. Naughten, 1982 .

Free Amino Acids in Human Amniotic Fluid. A Quantitative Study by Ion-Exchange Chromatography

H. Levy, Paul P Montag, 1969, Pediatric Research.

Long-term outcome of expanded newborn screening at Boston children’s hospital: benefits and challenges in defining true disease

S. Waisbren, H. Levy, Y. Landau, 2017, Journal of Inherited Metabolic Disease.

The clinical aspects of newborn screening: importance of newborn screening follow-up.

H. Levy, P. James, 2006, Mental retardation and developmental disabilities research reviews.

Advances in newborn screening for biochemical genetic disorders

H. Levy, I. Sahai, 2005 .

Effect of expanded newborn screening for biochemical genetic disorders on child outcomes and parental stress.

M. Seashore, S. Waisbren, M. Msall, 2004, JAMA.

One More Thought on Sudden Infant Death Syndrome

H. Levy, S. Albers, 2001, Pediatrics.

Reduction of false negative results in screening of newborns for homocystinuria.

J. R. Simmons, H. Levy, M. Peterschmitt, 1999, The New England journal of medicine.

Detection of neonatal carnitine palmitoyltransferase II deficiency by expanded newborn screening with tandem mass spectrometry.

A. Stark, H. Levy, D. Marsden, 2001, Pediatrics.

Results of a screening method for free amino acids II. Urine

H. Levy, V. Shih, R. A. MacCready, 1967 .

Evidence for liver disease preceding amino acid abnormalities in hereditary tyrosinemia.

J. Haddow, G. Knight, H. Levy, 1983, The New England journal of medicine.

A defect in intestinal amino acid transport in Lowe's syndrome.

H. Levy, J. Crawford, C. Bartsocas, 1969, American journal of diseases of children.

Evidence for Central Nervous System Glial Cell Plasticity in Phenylketonuria

A. Kendler, H. Levy, Jonathan C. Cruz, 1996, Journal of neuropathology and experimental neurology.

Phenylalanine ammonia lyase (PAL): From discovery to enzyme substitution therapy for phenylketonuria.

H. Levy, C. Scriver, C. Sarkissian, 2018, Molecular genetics and metabolism.

Effi cacy of sapropterin dihydrochloride ( tetrahydrobiopterin , 6 RBH 4 ) for reduction of phenylalanine concentration in patients with phenylketonuria : a phase III randomised placebo-controlled study

A. Chakrapani, H. Levy, M. Cleary, 2007 .

Relationship Among Genotype, Biochemical Phenotype, and Cognitive Performance in Females With Phenylalanine Hydroxylase Deficiency: Report From the Maternal Phenylketonuria Collaborative Study

R. Matalon, P. Guldberg, R. Koch, 1999, Pediatrics.

Phenylketonuria: old disease, new approach to treatment.

H. Levy, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Arginase Deficiency in Macaca fascicularis. I. Arginase Activity and Arginine Concentration in Erythrocytes and in Liver

H. Levy, V. Shih, P. Madigan, 1972, Pediatric Research.

Maternal phenylketonuria syndrome: congenital heart defects, microcephaly, and developmental outcomes.

R. Koch, C. Azen, H. Levy, 2000, The Journal of pediatrics.

Dietary cholesterol, serum cholesterol, and risks of cardiovascular and noncardiovascular diseases

H. Levy, 1998 .

Maternal phenylketonuria: a metabolic teratogen.

H. Levy, M. Ghavami, 1996, Teratology.

Hypermethioninemia with other hyperaminoacidemias. Studies in infants on high-protein diets.

H. Levy, J. Crawford, V. Shih, 1969, American journal of diseases of children.

The Natural History of Homocystinura Due to Cystathionine jP-Synthase Deficiency

K. Pettigrew, G. Boers, G. Andria, 2006 .

Histidinaemia. Part III: Impact; a prospective study

H. Levy, C. Scriver, B. Kammerer, 1983, Journal of Inherited Metabolic Disease.

Pericardial fluid analysis in scleroderma (systemic sclerosis).

D. Gladman, M. Urowitz, H. Levy, 1976, The American journal of medicine.

Maternal non-phenylketonuric mild hyperphenylalaninemia

S. Waisbren, A. Leviton, R. Koch, 2009, European Journal of Pediatrics.

Maternal mild hyperphenylalaninaemia: an international survey of offspring outcome

S. Waisbren, Á. Schuler, E. Allred, 1994, The Lancet.

The current status of newborn screening.

M. Mitchell, H. Levy, Harvey L. Levy, 1982, Hospital practice.

Maternal phenylketonuria and hyperphenylalaninemia. An international survey of the outcome of untreated and treated pregnancies.

H. Levy, R. Lenke, 1980, The New England journal of medicine.

Massachusetts metabolic disorders screening program. I. Technics and results of urine screening.

H. Levy, V. Shih, P. Madigan, 1972, Pediatrics.

Effects of untreated maternal phenylketonuria and hyperphenylalaninemia on the fetus.

S. Waisbren, H. Levy, 1983, The New England journal of medicine.

Newborn Urine Screening

H. Levy, V. Shih, J. Coulombe, 1980 .

A germline or de novo mutation in two families with Gaucher disease: implications for recessive disorders

E. Sidransky, H. Baris, H. Levy, 2012, European Journal of Human Genetics.

Nonenzymatically galactosylated serum albumin in a galactosemic infant.

H. Levy, J. Crawford, M. Cohenford, 1982, The New England journal of medicine.

Hypoglycinaemia and psychomotor delay in a child with xeroderma pigmentosum

K. Kraemer, D. Whiteman, H. Levy, 1999, Journal of Inherited Metabolic Disease.

Methionine Adenosyltransferase Deficiency

J. Chou, H. Levy, K. Lei, 2020, Definitions.

Mudd’s disease (MAT I/III deficiency): a survey of data for MAT1A homozygotes and compound heterozygotes

H. Blom, Y. Chien, W. Hwu, 2015, Orphanet Journal of Rare Diseases.

Isolated hypermethioninemia: measurements of S-adenosylmethionine and choline.

D. Jenden, H. Levy, C. Wagner, 2000, Metabolism: clinical and experimental.

Isolated persistent hypermethioninemia.

H. Levy, A. Tangerman, S. Mudd, 1995, American journal of human genetics.

Molecular mechanisms of an inborn error of methionine pathway. Methionine adenosyltransferase deficiency.

J. Chou, H. Levy, K. Lei, 1995, The Journal of clinical investigation.

New Developments in Hyperphenylalaninemia

E. McCabe, G. Donnell, D. O'brien, 1980, Pediatrics.

Predictors of intelligence quotient and intelligence quotient change in persons treated for phenylketonuria early in life.

S. Waisbren, B. Mahon, H. Levy, 1987, Pediatrics.

The Genetic Landscape and Epidemiology of Phenylketonuria.

V. Stoppioni, J. Vockley, B. Burton, 2020, American journal of human genetics.

First 1.5 years of pegvaliase clinic: Experiences and outcomes

H. Levy, Benjamin D. Goodlett, A. Kritzer, 2020, Molecular genetics and metabolism reports.

Nutritional therapy for selected inborn errors of metabolism.

H. Levy, 1989, Journal of the American College of Nutrition.

Prenatal diagnosis of glycine encephalopathy.

B. Wolf, H. Levy, V. Shih, 1982, The New England journal of medicine.

Phenylketonuria and Its Implications

H. Levy, 2006 .

The Hartnup phenotype: Mendelian transport disorder, multifactorial disease.

C. Laberge, B. Mahon, B. Lemieux, 1987, American journal of human genetics.

Plasma homocyst(e)ine or homocysteine?

H. Levy, S. Mudd, 1995, The New England journal of medicine.

Novel mutations in the GALK1 gene in patients with galactokinase deficiency

L. Kalaydjieva, H. Levy, D. Angelicheva, 2001, Human mutation.

Galactosemia: the uridine diphosphate galactose deficiency-uridine treatment controversy.

H. Levy, J. Holton, F. de la Cruz, 1993, The Journal of pediatrics.

The international collaborative study of maternal phenylketonuria: status report 1998

S. Waisbren, R. Koch, L. Platt, 2000, European Journal of Pediatrics.

The international study of pregnancy outcome in women with maternal phenylketonuria: report of a 12-year study.

R. Koch, F. Güttler, L. Platt, 2000, American journal of obstetrics and gynecology.

Pegvaliase for the treatment of phenylketonuria: Results of a long-term phase 3 clinical trial program (PRISM).

K. Larimore, J. Vockley, D. Dimmock, 2018, Molecular genetics and metabolism.

Present newborn screening for phenylketonuria

H. Levy, F. Dougherty, 1999 .

A Life in Newborn Screening

H. Levy, 2016 .

Sudden death in medium chain acyl-coenzyme a dehydrogenase deficiency (MCADD) despite newborn screening.

S. Waisbren, D. Finegold, E. Naylor, 2010, Molecular genetics and metabolism.

Glycomacropeptide for nutritional management of phenylketonuria: a randomized, controlled, crossover trial12

F. Rohr, H. Levy, G. Rice, 2016, The American journal of clinical nutrition.

Metabolomic changes demonstrate reduced bioavailability of tyrosine and altered metabolism of tryptophan via the kynurenine pathway with ingestion of medical foods in phenylketonuria.

F. Rohr, H. Levy, D. Ney, 2017, Molecular genetics and metabolism.

Molecular analysis of the inheritance of phenylketonuria and mild hyperphenylalaninemia in families with both disorders.

F. Ledley, H. Levy, S. Woo, 1986, The New England journal of medicine.

Effect of mutation on maternal–fetal metabolic homeostasis: maternal aminoacidopathies

H. Levy, 1985 .

Histidinaemia. Part I: Reconciling retrospective and prospective findings

H. Levy, C. Scriver, 1983, Journal of Inherited Metabolic Disease.

Necessity of complete intake of phenylalanine-free amino acid mixture for metabolic control of phenylketonuria.

F. Rohr, H. Levy, A. Slonim, 1999, Journal of the American Dietetic Association.

Recommendations for evaluation of responsiveness to tetrahydrobiopterin (BH(4)) in phenylketonuria and its use in treatment.

S. Cederbaum, B. Burton, H. Levy, 2007, Molecular genetics and metabolism.

Newborn screening conditions: What we know, what we do not know, and how we will know it

H. Levy, 2010, Genetics in Medicine.

Mutation analysis in families with discordant phenotypes of phenylalanine hydroxylase deficiency. Inheritance and expression of the hyperphenylalaninaemias

P. Guldberg, R. Koch, F. Güttler, 1994, Journal of Inherited Metabolic Disease.

Three prevalent mutations in a patient with phenylalanine hydroxylase deficiency: implications for diagnosis and genetic counselling.

P. Guldberg, F. Guttler, H. Levy, 1996, Journal of medical genetics.

Persistent mild hyperphenylalaninemia in the untreated state. A prospective study.

J. Kennedy, H. Levy, V. Shih, 1971, The New England journal of medicine.

Impact of the phenylalanine hydroxylase gene on maternal phenylketonuria outcome.

P. Guldberg, R. Koch, A. Romstad, 2003, Pediatrics.

Parental response to repeat testing of infants with 'false-positive' results in a newborn screening program.

J. Sorenson, H. Levy, S. Sepe, 1984, Pediatrics.

Molecular genetics of phenylketonuria and its implications.

H. Levy, 1989, American journal of human genetics.

Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency

H. Levy, J. Picker, 2014 .

Routine newborn screening for histidinemia. Clinical and biochemical results.

H. Levy, V. Shih, P. Madigan, 1974, The New England journal of medicine.

Thiamine-responsive intermittent branched-chain ketoaciduria.

H. Levy, S. Pueschel, V. Shih, 1979 .

Partial biotinidase deficiency: clinical and biochemical features.

M. Blitzer, B. Wolf, H. Levy, 1990, The Journal of pediatrics.

The North American Collaborative Study of Maternal Phenylketonuria. Status report 1993.

R. Matalon, R. Koch, C. Azen, 1993, American journal of diseases of children.

A derangement in B 12 metabolism leading to homocystinemia, cystathioninemia and methylmalonic aciduria.

H. Levy, S. Mudd, R. Abeles, 1969, Biochemical and biophysical research communications.

Pulmonary hypertension associated with nonketotic hyperglycinaemia

D. Wessel, H. Levy, H. Kozakewich, 2000, Journal of Inherited Metabolic Disease.

Comparison of erythrocyte uridine sugar nucleotide levels in normals, classic galactosemics, and patients with other metabolic disorders.

L. Elsas, G. Berry, H. Levy, 1995, Metabolism: clinical and experimental.

Early Development of Newborn Screening for HCU and Current Challenges

H. Levy, 2021, International journal of neonatal screening.

A rapid procedure for the determination of phenylalanine and tyrosine from blood filter paper specimens.

H. Levy, P. Madigan, P. C. Baullinger, 1971, Clinica chimica acta; international journal of clinical chemistry.

Lysinuric protein intolerance presenting as childhood osteoporosis. Clinical and skeletal response to citrulline therapy.

H. Levy, V. Shih, C. Anast, 1985, The New England journal of medicine.

Metabolic disorders in the center of genetic medicine.

H. Levy, 2005, The New England journal of medicine.

Vitreous hemorrhage as an ophthalmic complication of galactosemia.

E. de Juan, H. Levy, A. E. Brown, 1996, The Journal of pediatrics.

Cardiovascular risk in heterozygotes for homocystinuria.

R. Havlik, M. Feinleib, V. McKusick, 1982, American journal of human genetics.

Maternal phenylketonuria: magnetic resonance imaging of the brain in offspring.

P. Barnes, H. Levy, T. Poussaint, 1996, The Journal of pediatrics.

Outcome in offspring of women with mild hyperphenylalaninaemia

S. Waisbren, A. Leviton, H. Levy, 1995, The Lancet.

Hyperphenylalaninemia and the genomic revolution.

H. Levy, F. Rajabi, 2015, Molecular genetics and metabolism.

Cerebrospinal fluid neurotransmitter metabolites in neurologically normal infants and children.

E. Bird, P. Langlais, H. Levy, 1985, Pediatrics.

Rapid diagnosis of homocystinuria and other hypermethioninemias from newborns' blood spots by tandem mass spectrometry.

Millington, D. Millington, B. Adam, 1996, Clinical chemistry.

Phenylketonuria Scientific Review Conference: state of the science and future research needs.

Melissa L McPheeters, Mary Lou Lindegren, Anita MacDonald, 2014, Molecular genetics and metabolism.

Subacute combined degeneration of the spinal cord in cblC disorder despite treatment with B12.

H. Kinney, K. Swoboda, H. Levy, 2006, Molecular genetics and metabolism.

Expanded newborn screening using tandem mass spectrometry.

H. Levy, Marsha K Fearing, Harvey L Levy, 2003, Advances in pediatrics.

Bilateral lucency of the globus pallidus complicating methylmalonic acidemia

B. Korf, H. Levy, J. Wallman, 1986, Annals of neurology.

Intentional infantile ethylene glycol poisoning presenting as an inherited metabolic disorder.

A. Woolf, A. Wynshaw-Boris, P. Rinaldo, 1992, The Journal of pediatrics.

Canine cystinuria: its urinary amino acid pattern and genetic analysis.

T. C. Jones, M. Tsan, H. Levy, 1972, American journal of veterinary research.

A simple indirect method of detecting the enzyme defect in histidinemia.

H. Levy, V. Shih, H. Baden, 1969, The Journal of pediatrics.

Epidermis in histidinemia.

M. Pathak, H. Levy, H. Baden, 1969, Archives of dermatology.

Newborn screening by tandem mass spectrometry: a new era.

H. Levy, 1998, Clinical chemistry.

Newborn Screening for Glutaric Aciduria-II: The New England Experience.

C. Phornphutkul, E. Neilan, H. Levy, 2013, JIMD reports.

Ketoacidotic crisis as a presentation of mild ("benign") methylmalonic acidemia.

F. Ledley, H. Levy, D. Rosenblatt, 1991, The Journal of pediatrics.

Benign methylmalonic aciduria.

F. Ledley, H. Levy, V. Shih, 1984, The New England journal of medicine.

Massachusetts Metabolic Disorders Screening Program. II. Methylmalonic aciduria.

H. Levy, V. Shih, J. Coulombe, 1981, Pediatrics.

A new method of screening for inherited disorders of galactose metabolism.

K. Paigen, H. Levy, F. Pacholec, 1982, The Journal of laboratory and clinical medicine.

Diet termination in children with phenylketonuria: a review of psychological assessments used to determine outcome

S. Waisbren, H. Levy, R. Schnell, 1980, Journal of Inherited Metabolic Disease.

Measurement of methylmalonic acid in urine filter paper specimens by gas chromatography.

J. Evans, H. Levy, V. Shih, 1981, Clinica chimica acta; international journal of clinical chemistry.

Metabolic syndromes with dermatologic manifestations

H. Levy, M. Irons, 1986, Clinical reviews in allergy.

Abnormal cobalamin metabolism in a megaloblastic child with homocystinuria, cystathioninuria and methylmalonic aciduria

H. Levy, J. Linnell, S. Dowton, 1983, Journal of Inherited Metabolic Disease.

A derangement in B12 metabolism associated with homocystinemia, cystathioninemia, hypomethioninemia and methylmalonic aciduria.

J. Schulman, H. Levy, S. Mudd, 1970, The American journal of medicine.

Evidence- and consensus-based recommendations for the use of pegvaliase in adults with phenylketonuria

J. Vockley, B. Burton, N. Longo, 2018, Genetics in Medicine.

Cognitive function in early treated biotinidase deficiency: Follow-up of children detected by newborn screening

S. Waisbren, H. Levy, J. Warner-Rogers, 1995 .

Newborn screening for biotinidase deficiency: pilot study and follow-up of identified cases

B. Wolf, H. Levy, M. Lawler, 1992 .

Genetic screening of newborns.

H. Levy, S. Albers, Harvey L. Levy, 2003, Annual review of genomics and human genetics.

Partial biotinidase deficiency' and biochemical features Clinical

M. Blitzer, B. Wolf, H. Levy, 1990 .

Effect of Expanded Newborn Screening for Biochemical Genetic Disorders on Child Outcomes and Parental Stress

Edwin W. Naylor, Michael E. Msall, M. Seashore, 2003 .

Maternal gamma-cystathionase deficiency: absence of both teratogenic effects and pregnancy complications.

S. Waisbren, H. Levy, S. Mudd, 1999, American journal of obstetrics and gynecology.

The International Collaborative Study of Maternal Phenylketonuria Status Report 1998

S. Waisbren, R. Koch, K. Michals‐Matalon, 1999 .

Maternal Hartnup disorder.

B. Mahon, H. Levy, 1986, American journal of medical genetics.

Tyrosine supplementation in the treatment of maternal phenylketonuria.

F. Rohr, H. Levy, D. Lobbregt, 1998, The American journal of clinical nutrition.

Clinical and therapeutic observations in aromatic l-amino acid decarboxylase deficiency

D. Goldstein, K. Swoboda, H. Levy, 1999, Neurology.

The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

K. Pettigrew, G. Boers, R. Pyeritz, 1985, American journal of human genetics.

New galactose metabolic abnormality

H. Levy, S. Sepe, 1976 .

Atypical Nonketotic Hyperglycinemia With Normal Cerebrospinal Fluid to Plasma Glycine Ratio

S. Kure, H. Levy, D. Applegarth, 1999, Journal of child neurology.

Prenatal diagnosis of non‐ketotic hyperglycinemia

H. Levy, V. Shih, L. Kirby, 1986, Prenatal diagnosis.

Robert Guthrie and the Trials and Tribulations of Newborn Screening

H. Levy, 2021, International journal of neonatal screening.

Deranged B12 metabolism: Effects on sulfur amino acid metabolism

H. Levy, S. Mudd, G. Morrow, 1970 .

Infantile hypermethioninemia and hyperhomocysteinemia due to high methionine intake: a diagnostic trap.

M. Pomper, P. Jayakar, N. Braverman, 2003, Molecular genetics and metabolism.

Speech and Histidinemia: Methodology and Evaluation of Four Cases

H. Levy, I. Lott, Ira T. Lott, 1970, Developmental medicine and child neurology.

Comparison of amino acid concentrations between plasma and erythrocytes. Studies in normal human subjects and those with metabolic disorders.

H. Levy, E. Barkin, 1971, The Journal of laboratory and clinical medicine.

Agoraphobia in phenylketonuria

S. Waisbren, H. Levy, 1991, Journal of Inherited Metabolic Disease.

Phenylalanine blood levels and clinical outcomes in phenylketonuria: a systematic literature review and meta-analysis.

S. Waisbren, K. Fahrbach, H. Levy, 2007, Molecular genetics and metabolism.

Tyrosine supplementation in phenylketonuria: diurnal blood tyrosine levels and presumptive brain influx of tyrosine and other large neutral amino acids.

K. Strauss, F. Rohr, H. Levy, 2001, The Journal of pediatrics.

Maternal phenylketonuria collaborative study, obstetric aspects and outcome: the first 6 years.

R. Koch, L. Platt, C. Azen, 1992 .

Pancreatic involvement in patients with inborn errors of metabolism

J. Y. Kim, H. Levy, Y. Kim, 2021, Orphanet Journal of Rare Diseases.

Hydroxyprolinemia: comparison of a patient and her unaffected twin sister.

S. Waisbren, L. Varvogli, H. Levy, 1997, The Journal of pediatrics.

Rennes-like variant of galactosemia: clinical and biochemical studies.

H. Levy, G. Hammersen, S. Houghton, 1975, The Journal of pediatrics.

Comparison of galactose-1-phosphate uridyl transferase in fetal and adult tissues.

H. Levy, F. Frigoletto, G. Hammersen, 1975, Clinica chimica acta; international journal of clinical chemistry.

The hypergonadotropic hypogonadism conundrum of classic galactosemia

L. Wilkins-Haug, G. Berry, H. Levy, 2022, Human reproduction update.

Starch gel electrophoresis for galactose-1-phosphate uridylyl-transferase applied to dried filter paper blood specimens.

H. Levy, G. Hammersen, 1977, Clinica chimica acta; international journal of clinical chemistry.

Retinal degeneration in vitamin B12 disorder associated with methylmalonic aciduria and sulfur amino acid abnormalities.

A. Fulton, H. Levy, R. Robb, 1984, American journal of ophthalmology-glaucoma.

Screening for congenital hypothyroidism. Results in the newborn population of New England.

M. Mitchell, P. Larsen, H. Levy, 1978, JAMA.

Screening for galactosaemia

H. Levy, 1980 .

Characterization of two missense mutations in human galactose-1-phosphate uridyltransferase: different molecular mechanisms for galactosemia.

J. Belmont, J. Reichardt, H. Levy, 1992, Genomics.

Newborn screening for galactosemia and other galactose metabolic defects.

H. Levy, G. Hammersen, 1978, The Journal of pediatrics.

Molecular characterization of two galactosemia mutations and one polymorphism: implications for structure-function analysis of human galactose-1-phosphate uridyltransferase.

J. Reichardt, H. Levy, S. Woo, 1992, Biochemistry.

Ovarian failure in galactosemia.

H. Levy, S. Driscoll, R. Porensky, 1984, The New England journal of medicine.

Erythrocyte uridine diphosphate galactose-4- epimerase deficiency identified by newborn screening for galactosemia in the United States

T. Cowan, H. Bock, M. Blitzer, 1993 .

Prevention of Fetal Damage Through Dietary Control of Maternal Hyperphenylalaninemia

H. Levy, R. Erbe, M. Ghavami, 1986, Clinical obstetrics and gynecology.

Outcome at age 4 years in offspring of women with maternal phenylketonuria: the Maternal PKU Collaborative Study.

S. Waisbren, R. Matalon, R. Koch, 2000, JAMA.

A missense mutation (I278T) in the cystathionine beta-synthase gene prevalent in pyridoxine-responsive homocystinuria and associated with mild clinical phenotype.

V. Ramesh, J. Fringer, G. Berry, 1995, American journal of human genetics.

Folinic acid therapy in treatment of dihydropteridine reductase deficiency.

S. Milstien, S. Kaufman, P. Langlais, 1987, The Journal of pediatrics.

Short-chain acyl-CoA dehydrogenase (SCAD) deficiency: an examination of the medical and neurodevelopmental characteristics of 14 cases identified through newborn screening or clinical symptoms.

S. Waisbren, N. Gregersen, D. Matern, 2008, Molecular genetics and metabolism.

Laboratory diagnosis of 1,4-BD and GHB overdose by routine urine organic acid analysis.

A. Woolf, E. Boyer, H. Levy, 2005, Clinical toxicology.

Neonatal hemochromatosis: diagnosis with MR imaging.

H. Levy, D. Jaramillo, A. Knisely, 1992, AJR. American journal of roentgenology.

Isovaleric acidemia: results of family study and dietary treatment.

I. Lott, H. Levy, A. M. Erickson, 1973, Pediatrics.

Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia.

H L Levy, T D Schneider, Sikandar G. Khan, 1998, The Journal of investigative dermatology.

Neonatal screening for medium-chain acyl-CoA dehydrogenase deficiency

S. Waisbren, H. Levy, J. Picker, 2002, The Lancet.

Massachusetts metabolic disorders screening program

H. Levy, P. Madigan, V. Sinn, 1973 .

A VARIANT OF CARNOSINEMIA WITH NORMAL SERUM CARNOSINASE ACTIVITY IN AN INFANT

H. Levy, S. Sepe, J. Coulombe, 1977, Pediatric Research.

10 Neonatal screening for inborn errors of amino acid metabolism

H. Levy, 1974 .

Can Newborn Screening for Vitamin B12 Deficiency be Incorporated into All Newborn Screening Programs?

H. Levy, S. Hawthorne, 2019, The Journal of pediatrics.

Plasma amino acid levels after single-dose aspartame consumption in phenylketonuria, mild hyperphenylalaninemia, and heterozygous state for phenylketonuria.

R. Wurtman, B. Mahon, F. Rohr, 1986, The Journal of pediatrics.

Genetic biochemical disorders: by P. F. Benson and A. H. Fensom, Oxford University Press, 1985. £55.00 (xx + 692 pages) ISBN 0 19 261193 3)

H. Levy, M. Irons, 1986 .

The use of betaine in the treatment of elevated homocysteine.

H. Levy, A. Lawson-Yuen, 2006, Molecular genetics and metabolism.

Results of a screening method for free amino acids

H. Levy, V. Shih, R. A. MacCready, 1967 .

Problems in Genetic Screening which Confront the Law

H. Levy, 1976 .

Asymptomatic type II hyperprolinaemia associated with hyperglycinaemia in three sibs.

H. Levy, L. Pavone, F. Mollica, 1975, Archives of disease in childhood.

Deranged B12 metabolism: Studies of fibroblasts grown in tissue culture

H. Levy, S. Mudd, B. Uhlendorf, 1970 .

Revising the Psychiatric Phenotype of Homocystinuria

S. Waisbren, H. Levy, J. Picker, 2019, Genetics in Medicine.

The problem of maternal phenylketonuria.

H. Levy, R. A. MacCready, R. MacCready, 1972, American journal of obstetrics and gynecology.

Screening the "normal" population in Massachusetts for phenylketonuria.

H. Levy, S. Houghton, R. A. MacCready, 1970, The New England journal of medicine.

Transient tyrosinemia in full-term infants.

H. Levy, V. Shih, R. A. MacCready, 1969, JAMA.

Histidinaemia. Part II: Impact; a retrospective study

H. Levy, C. Scriver, A. Rosenmann, 1983, Journal of Inherited Metabolic Disease.

Early newborn specimen: Survey of practices among newborn screening programs in the United States

H. Levy, G. Grady, C. Walraven, 1995 .

Severe folate deficiency and pancytopenia in a nutritionally deprived infant and homocystinuria caused by cystathionine beta-synthase deficiency.

J. Wagstaff, J. Kraus, H. Levy, 1991, The Journal of pediatrics.

Detection of phenylketonuria in the very early newborn blood specimen.

F. Rohr, H. Levy, L. Doherty, 1991, Pediatrics.

Cystathioninuria and homocystinuria.

H. Levy, S. Mudd, B. Uhlendorf, 1975, Clinica chimica acta; international journal of clinical chemistry.

Historical background for the maternal PKU syndrome.

H. Levy, 2003, Pediatrics.

Comparison of phenylketonuric and nonphenylketonuric sibs from untreated pregnancies in a mother with phenylketonuria.

H. Levy, C. Sansaricq, S. Snyderman, 1992, American journal of medical genetics.

Postnatal clearance of maternally derived phenylalanine in offspring of maternal phenylketonuria: implications for newborn screening

H. Levy, D. Lobbregt, 1995 .

Maternal phenylketonuria--results of dietary therapy.

H. Levy, R. Lenke, 1982, American journal of obstetrics and gynecology.

Comparison of treated and untreated pregnancies in a mother with phenylketonuria.

H. Levy, A. M. Erickson, G. N. Kaplan, 1982, The Journal of pediatrics.

Congenital heart disease in maternal PKU.

H. Levy, 2012, Molecular genetics and metabolism.

Comparison in a mother of treated and untreated pregnancies with phenylketonuria

H. Levy, A. M. Erickson, G. N. Kaplan, 1982 .

Dominant inheritance of isolated hypermethioninemia is associated with a mutation in the human methionine adenosyltransferase 1A gene.

J. Chou, H. Levy, M. Chamberlin, 1997, American journal of human genetics.

Congenital Heart Disease in Maternal Phenylketonuria: Report from the Maternal PKU Collaborative Study

P. Guldberg, R. Koch, F. Güttler, 2001, Pediatric Research.

New England Maternal PKU Project: prospective study of untreated and treated pregnancies and their outcomes.

S. Waisbren, F. Rohr, H. Levy, 1987, The Journal of pediatrics.

The North American collaborative study of maternal phenylketonuria (PKU)

R. Koch, C. Azen, H. Levy, 1993 .

The New England Maternal PKU Project: identification of at-risk women.

S. Waisbren, F. Rohr, H. Levy, 1988, American journal of public health.

Maternal PKU: control of an emerging problem.

H. Levy, 1982, American journal of public health.

Comments on final intelligence in late treated patients with phenylketonuria

H. Levy, 2000, European Journal of Pediatrics.

Genetic screening for inborn errors of metabolism

J. Kennedy, H. Levy, 1975 .

Tyrosinosis: a patient without liver or renal disease.

H. Levy, R. Atkins, T. S. Hosty, 1971, Pediatrics.

Methionine adenosyltransferase I/III deficiency: two Korean compound heterozygous siblings with a novel mutation

F. Corrales, E. Santamaría, J. Mato, 2003, Journal of Inherited Metabolic Disease.

Maternal methionine adenosyltransferase I/III deficiency: Reproductive outcomes in a woman with four pregnancies

S. Zeisel, H. Levy, A. Tangerman, 2003, Journal of Inherited Metabolic Disease.

Asymptomatic Type II Hyperprolinemia Associated with Hyperglycinemia in Three Siblings

H. Levy, L. Pavone, F. Mollica, 1974 .

Prospective study of early neonatal screening for phenylketonuria.

D. Meryash, H. Levy, R. Guthrie, 1981, The New England journal of medicine.

838 MATERNAL HISTIDINEMIA: STUDY OF FAMILIES IDENTIFIED BY ROUTINE CORD BLOOD SCREENING

H. Levy, R. Benjamin, 1985, Pediatric Research.

The use of gelatin capsules for ingestion of formula in dietary treatment of maternal phenylketonuria

H. Levy, H. Kecskemethy, D. Lobbregt, 1993, Journal of Inherited Metabolic Disease.

Pregnancy experiences in the woman with mild hyperphenylalaninemia.

S. Waisbren, R. Koch, F. Güttler, 2003, Pediatrics.

Maternal mild hyperphenylalaninemia: results of treated and untreated pregnancies in two sisters.

P. Guldberg, F. Güttler, H. Levy, 1994, The Journal of pediatrics.

Cross-cultural perspectives on coping with the risks of maternal phenylketonuria

S. Waisbren, S. Shiloh, H. Levy, 1993 .

Psychosocial factors in maternal phenylketonuria: prevention of unplanned pregnancies.

S. Waisbren, S. Shiloh, H. Levy, 1991, American journal of public health.

Effects of untreated maternal hyperphenylalaninemia on the fetus: further study of families identified by routine cord blood screening.

S. Waisbren, H. Levy, 1990, The Journal of pediatrics.

Prenatal diagnosis of Non-ketotic hyperglycinaemia

H. Levy, D. Applegarth, J. Toone, 1992, Journal of Inherited Metabolic Disease.

Molecular genetic and potential biochemical characteristics of patients with T-protein deficiency as a cause of glycine encephalopathy (NKH).

M. Coulter-Mackie, H. Levy, Gary Lee, 2003, Molecular genetics and metabolism.

Prenatal diagnosis of nonketotic hyperglycinemia.

H. Levy, V. Shih, J. M. García-Castro, 1982, The New England journal of medicine.

Prenatal diagnosis of non-ketotic hyperglycinaemia: Experience in 50 at-risk pregnancies

H. Levy, D. Applegarth, J. Toone, 1994, Journal of Inherited Metabolic Disease.

Hepatocellular carcinoma despite long-term survival in chronic tyrosinaemia I

E. Holme, H. Levy, R. Tanguay, 2000, Journal of Inherited Metabolic Disease.

Clinical and biochemical characteristics of prolidase deficiency in siblings.

V. D. Der Kaloustian, H. Levy, M. Deeb, 1984, American journal of medical genetics.

The Maternal Phenylketonuria International Study: 1984-2002.

S. Waisbren, K. Widaman, R. Koch, 2003, Pediatrics.

The North American Maternal Phenylketonuria Collaborative Study, developmental assessment of the offspring: preliminary report

R. Koch, C. Azen, H. Levy, 2009, European Journal of Pediatrics.

Maternal Phenylketonuria: Long-term Outcomes in Offspring and Post-pregnancy Maternal Characteristics.

S. Waisbren, A. Ozonoff, F. Rohr, 2015, JIMD reports.

FETAL ULTRASONOGRAPHY IN MATERNAL PKU

L. Platt, H. Levy, B. Benacerraf, 1996, Prenatal diagnosis.

Neonatal neurological assessment of offspring in maternal phenylketonuria

S. Waisbren, R. Koch, E. Allred, 1998, Journal of Inherited Metabolic Disease.

Delayed increase in blood phenylalanine concentration in phenylketonuric children initially classified as mild hyperphenylalaninemia

H. Levy, W. Hanley, C. Berlin, 1995 .

Cord-blood tyrosine levels in the full-term phenylketonuric fetus and the "justification hypothesis".

C. Laberge, D. Cole, H. Levy, 1980, Proceedings of the National Academy of Sciences of the United States of America.

An evaluation of routine follow-up blood screening of infants for phenylketonuria.

H. Levy, S. Sepe, F. Mount, 1979, The New England journal of medicine.

TheNewEngland Maternal PKU Project: Identification ofAt-Risk Women

F. Rohr, H. Levy, I. Bailey, 1988 .

A missense mutation (Q279R) in the Fumarylacetoacetate Hydrolase gene, responsible for hereditary tyrosinemia, acts as a splicing mutation

H. Levy, R. Tanguay, A. Bergeron, 2001, BMC Genetics.

Newborn Metabolic Screening: Past and Prospect

H. Levy, 1975 .

Metabolomic Markers of Essential Fatty Acids, Carnitine, and Cholesterol Metabolism in Adults and Adolescents with Phenylketonuria.

Katarzyna A. Broniowska, F. Rohr, H. Levy, 2018, The Journal of nutrition.

Metabolomic Insights into the Nutritional Status of Adults and Adolescents with Phenylketonuria Consuming a Low-Phenylalanine Diet in Combination with Amino Acid and Glycomacropeptide Medical Foods

F. Rohr, H. Levy, D. Ney, 2017, Journal of nutrition and metabolism.

Dietary amino acid intakes associated with a low-phenylalanine diet combined with amino acid medical foods and glycomacropeptide medical foods and neuropsychological outcomes in subjects with phenylketonuria

F. Rohr, H. Levy, D. Ney, 2017, Data in brief.

Brief report: Predictors of parenting stress among parents of children with biochemical genetic disorders.

S. Waisbren, H. Levy, D. Marsden, 2004, Journal of pediatric psychology.

Free amino acids in extracts of cultured skin fibroblasts from patients with various amino acid metabolic disorders

J. Littlefield, H. Levy, V. Shih, 1975, Clinical genetics.

The Safety of Aspartame

S. Waisbren, H. Levy, 1987 .

Krabbe Disease: Severe Neonatal Presentation With a Family History of Multiple Sclerosis

V. Kimonis, H. Baris, H. Levy, 2005, Journal of child neurology.

Pericardial effusion in primary systemic carnitine deficiency

D. Wattanasirichaigoon, H. Levy, V. Shih, 2006, Journal of Inherited Metabolic Disease.

Accumulation of galactose-1-phosphate in the galactosemic fetus despite maternal milk avoidance.

H. Levy, S. Pueschel, M. Irons, 1985, The Journal of pediatrics.

Acute Illness Protocol for Maple Syrup Urine Disease

G. Berry, H. Levy, S. AlDubayan, 2018, Pediatric emergency care.

5-year retrospective analysis of patients with phenylketonuria (PKU) and hyperphenylalaninemia treated at two specialized clinics.

A. Seymour, J. Vockley, D. Lamppu, 2019, Molecular genetics and metabolism.

Ethical and Psychosocial Implications of Genomic Newborn Screening

H. Levy, 2021, International journal of neonatal screening.

High cognitive outcome in an adolescent with mut- methylmalonic acidemia.

S. Waisbren, G. Repetto, L. Varvogli, 2000, American journal of medical genetics.

Arginase deficiency with lethal neonatal expression: evidence for the glutamine hypothesis of cerebral edema.

K. Ligon, S. Cederbaum, H. Levy, 2003, The Journal of pediatrics.

Dietary treatment of an infant with isovaleric acidemia.

I. Lott, H. Levy, A. M. Erickson, 1972, Pediatrics.

Newborn screening: the genomic challenge

H. Levy, 2014, Molecular genetics & genomic medicine.

Elevated galactose in newborn screening due to congenital absence of the portal vein

M. Jonas, T. Laor, H. Levy, 1998, European Journal of Pediatrics.

Newborn screening compared to clinical identification of biochemical genetic disorders

M. Seashore, S. Waisbren, M. Msall, 2002, Journal of Inherited Metabolic Disease.

Newborn Screening: Toward a Uniform Screening Panel and System—Executive Summary

Michael S. Watson, Piero Rinaldo, B. Yawn, 2006, Pediatrics.

Longitudinal Studies on Metabolic Rate, Heat Loss, and Energy Cost of Growth in Low Birth Weight Infants

H. J. Dane, S. Proctor, P. Sauer, 1984, Pediatric Research.

Acceptability of a new modular protein substitute for the dietary treatment of phenylketonuria

F. Rohr, H. Levy, A. Munier, 2001, Journal of Inherited Metabolic Disease.

Maternal phenylketonuria: an international study.

R. Matalon, R. Koch, F. Guttler, 2000, Molecular genetics and metabolism.

MATERNAL PHENYLKETONURIA AND HYPERPHENYLALANINEMIA. A PROSPECTIVE STUDY

H. Levy, V. Shih, 1974, Pediatric Research.

Congenital Expression of Prolidase Defect in Prolidase Deficiency

H. Levy, M. Ampola, Naughten Er, 1984, Pediatric Research.

Stability of amino acids and galactose in the newborn screening filter paper blood specimen.

J. R. Simmons, H. Levy, R. A. MacCready, 1985, The Journal of pediatrics.

Research design, organization, and sample characteristics of the Maternal PKU Collaborative Study.

R. Koch, C. Azen, H. Levy, 2003, Pediatrics.

Adherence to tetrahydrobiopterin therapy in patients with phenylketonuria.

F. Rohr, H. Levy, Matthew Brown, 2015, Molecular genetics and metabolism.

Amoxycillin: A new Semi-synthetic Penicillin

M. J. Griffiths, G. Rolinson, H. Levy, 1972, British medical journal.

New England Consortium: A model for medical evaluation of expanded newborn screening with tandem mass spectrometry

M. Seashore, S. Waisbren, L. Demmer, 2001, Journal of Inherited Metabolic Disease.

Retinal degeneration in vitamin B12 disorder associated with methylmalonic aciduria and sulfur amino acid abnormalities.

A. Fulton, H. Levy, R. Robb, 1984, American journal of ophthalmology.

Folic acid deficiency secondary to a diet for maple syrup urine disease.

J. Littlefield, H. Levy, J. Truman, 1970, The Journal of pediatrics.

Increasing brain tyrosine in treated phenylketonuria

H. Levy, 1998, Journal of Inherited Metabolic Disease.

Genomics in newborn screening.

H. Levy, U. Lichter-Konecki, Y. Landau, 2014, The Journal of pediatrics.

Classical phenylketonuria presenting as maternal PKU syndrome in the offspring of an intellectually normal woman

A. O’Donnell-Luria, H. Levy, Naif A. M. Almontashiri, 2023, JIMD reports.

Current approaches to genetic metabolic screening in newborns.

H. Levy, A. Cornier, 1994, Current opinion in pediatrics.

Massachusetts Metabolic Disorders Screening Program: III. Sarcosinemia.

H. Levy, J. Coulombe, R. Benjamin, 1984, Pediatrics.

Reproductive fitness in maternal homocystinuria due to cystathionine β-synthase deficiency

S. Rosengren, E. Roeder, S. Waisbren, 2002, Journal of Inherited Metabolic Disease.

Untargeted metabolomics identifies unique though benign biochemical changes in patients with pathogenic variants in UROC1

K. Pappan, A. Kennedy, H. Levy, 2018, Molecular genetics and metabolism reports.

Relationship Among Genotype, Biochemical Phenotype, and Cognitive Performance in Females With Phenylalanine Hydroxylase Deficiency: Report From the Maternal Phenylketonuria Collaborative Study

R. Matalon, P. Guldberg, R. Koch, 1999, Pediatrics.

Acute Illness Protocol for Organic Acidemias: Methylmalonic Acidemia and Propionic Acidemia

G. Berry, H. Levy, S. AlDubayan, 2017, Pediatric emergency care.

Acute Illness Protocol for Fatty Acid Oxidation and Carnitine Disorders

G. Berry, H. Levy, S. AlDubayan, 2017, Pediatric emergency care.

Is More Effective Newborn Screening for Homocystinuria on the Horizon?

H. Levy, I. Sahai, 2023, Clinical chemistry.

Sudden death in medium chain acyl-coenzyme a dehydrogenase deficiency (MCADD) despite newborn screening.

S. Waisbren, D. Finegold, E. Naylor, 2010, Molecular genetics and metabolism.

Management of a Woman With Maple Syrup Urine Disease During Pregnancy, Delivery, and Lactation.

L. Wilkins-Haug, G. Berry, E. Neilan, 2015, JPEN. Journal of parenteral and enteral nutrition.

Acute Illness Protocol for Urea Cycle Disorders

G. Berry, H. Levy, S. AlDubayan, 2017, Pediatric emergency care.