J. Debernardis

发表

MRI and CSF studies in the early diagnosis of Alzheimer's disease

B. Reisberg, M. J. Leon, H. Rusinek, 2004, Journal of internal medicine.

CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease.

H. Soininen, H. Hampel, M. Ewers, 2006, Brain : a journal of neurology.

Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study.

Katharina Buerger, Harald Hampel, Kaj Blennow, 2004, Archives of general psychiatry.

A-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype.

J. Debernardis, A. Hancock, M. Brune, 1995, The Journal of pharmacology and experimental therapeutics.

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.

G. Perry, Xiongwei Zhu, A. Nunomura, 2005, Free radical biology & medicine.

Efficient peripheral functionalization of porphyrins

M. Crossley, J. Debernardis, J. Baldwin, 1982 .

Naturally occurring halogenated organic compounds.

J. Debernardis, J. Siuda, 1973, Lloydia.

Increased levels of CSF phosphorylated tau in apolipoprotein E ɛ4 carriers with mild cognitive impairment

K. Blennow, H. Hampel, M. Ewers, 2005, Neuroscience Letters.

Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment.

K. Blennow, H. Hampel, M. Ewers, 2005, Neuroscience letters.

A perspective on pharmaceutical industrial research on antihypertensive drugs

J. Debernardis, Jang Yun Lee, 1987 .

[3H]A-81988, a potent, selective, competitive antagonist radioligand for angiotensin AT1 receptors.

D. Kerkman, A. Tasker, J. Debernardis, 1994, European journal of pharmacology.

E. Bush, J. Debernardis, D. Walker, 1987, Journal of receptor research.

Differentiation of alpha-adrenergic receptors using pharmacological evaluation and molecular modeling of selective adrenergic agents.

Y. Martin, J. Debernardis, A. Hancock, 1988, Journal of receptor research.

A‐75169 HCI: Pharmacological profile and ocular pharmacology studies of a new α‐2 antagonist

J. Debernardis, A. Hancock, S. Buckner, 1993 .

Effects of the putative antidepressant, ABT 200, on the clearance of exogenous norepinephrine in rat cerebellum

G. Gerhardt, D. Kerkman, J. Debernardis, 1995, Synapse.

Photoaffinity labeling of mammalian alpha 1-adrenergic receptors. Identification of the ligand binding subunit with a high affinity radioiodinated probe.

M. Caron, J. Wikberg, R. Lefkowitz, 1984, Journal of Biological Chemistry.

Covalent labeling of the cerebral cortex alpha 1-adrenergic receptor with a new high affinity radioiodinated photoaffinity probe.

M. Caron, J. Wikberg, R. Lefkowitz, 1983, Biochemical and biophysical research communications.

Conformationally defined adrenergic agents. 1. Design and synthesis of novel alpha 2 selective adrenergic agents: electrostatic repulsion based conformational prototypes.

D. Kerkman, E. Bush, J. Debernardis, 1985, Journal of medicinal chemistry.

Orthostatic hypotension occurs following alpha 2-adrenoceptor blockade in chronic prazosin-pretreated conscious spontaneously hypertensive rats.

J. Debernardis, M. Brune, R. Warner, 1992, Journal of autonomic pharmacology.

Characterization of antihypertensive activity of ABBOTT-81988, a nonpeptide angiotensin II antagonist in the renal hypertensive rat.

D. Kerkman, J. Debernardis, M. Winn, 1994, The Journal of pharmacology and experimental therapeutics.

A novel three carbon-amino grignard reagent: its use in an efficient pyrrolidine synthesis

J. Debernardis, F. Basha, 1984 .

Synthesis and structure activity relationships of cis- and trans-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridines for 5-HT receptor subtypes.

J. Debernardis, A. Hancock, M. Meyer, 1994, Journal of Medicinal Chemistry.

Synthesis and Structure Activity Relationships of cis‐ and trans‐2,3,4, 4a,9,9a‐Hexahydro‐1H‐indeno(2,1‐c)pyridines for 5‐HT Receptor Subtypes.

J. Debernardis, A. Hancock, M. Meyer, 1994 .

Diastereoselection in the intramolecular diels-alder reaction of o-quinodimethanes.

J. Debernardis, F. Basha, W. Mcclellan, 1991 .

Conformationally defined adrenergic agents. 4. 1-(aminomethyl)phthalans: synthesis and pharmacological consequences of the phthalan ring oxygen atom.

D. Kerkman, J. Debernardis, J. Kyncl, 1987, Journal of medicinal chemistry.

Conformationally defined adrenergic agents. 3. Modifications to the carbocyclic ring of 5,6-dihydroxy-1-(2-imidazolinyl)tetralin: improved separation of alpha 1 and alpha 2 adrenergic activities.

D. Kerkman, J. Debernardis, J. Kyncl, 1986, Journal of medicinal chemistry.

Anion rearrangements: duality of mechanism in the decomposition of allylic ether anions and synthetic applications

J. Debernardis, J. Baldwin, J. Patrick, 1970 .

Evaluation of the side arm of (naphthylvinyl)pyridinium inhibitors of choline acetyltransferase.

D. Abraham, P. Gifford, J. Debernardis, 1988, Journal of medicinal chemistry.

Conformationally defined adrenergic agents. 5. Resolution, absolute configuration, and pharmacological characterization of the enantiomers of 2-(5,6-dihydroxy-1,2,3,4-tetrahydro-1-naphthyl)imidazoline: a potent agonist at alpha-adrenoceptors.

D. Kerkman, J. Debernardis, J. Kyncl, 1987, Journal of medicinal chemistry.

Synthesis of “capped porphyrins”

J. Almog, J. Huff, M. Crossley, 1981 .

The oxidation of tetraphenylporphyrinatoiron(III)hexafluoroantimonate with peroxylauric acid and t-butyl hydroperoxide

J. Debernardis, J. Baldwin, G. Haraldsson, 1993 .

Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.

M. Caron, R. Lefkowitz, J. Lomasney, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Calcium-induced vasocontractions after alpha-2 adrenergic receptor activation in the dog saphenous vein: comparison to calcium-induced contractions after potassium-depolarization.

J. Debernardis, M. Brune, J Y Lee, 1990, General pharmacology.

Cardiovascular Activity of A-74283, a 5-Hydroxytryptamine1A Agent, in the Spontaneously Hypertensive Rat

J. Debernardis, A. Hancock, M. Brune, 1998, Pharmacology.

Molecular design of novel ligands for 5-HT1A receptors.

J. Debernardis, A. Hancock, M. Meyer, 1991, Journal of receptor research.

Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease.

Alan C. Evans, Alan C Evans, Harald Hampel, 2005, Archives of neurology.

Detection of tau phosphorylated at threonine 231 in cerebrospinal fluid of Alzheimer's disease patients

H. Hampel, R. Zinkowski, D. Kerkman, 2000, Neuroscience Letters.

Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt–Jakob disease

K. Blennow, H. Hampel, J. Wiltfang, 2006, Neurobiology of Aging.

Synthesis and pharmacological characterization of ABT-200 : a putative novel antidepressant combining potent α-2 antagonism with moderate NE uptake inhibition

J. Debernardis, A. Hancock, M. Meyer, 1994 .

Actions of A-75200, a novel catecholamine uptake inhibitor, on norepinephrine uptake and release from bovine adrenal chromaffin cells.

G. Gerhardt, J. McKelvy, J. Debernardis, 1993, The Journal of pharmacology and experimental therapeutics.

Mammalian alpha 1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit.

M. Caron, R. Lefkowitz, J. Regan, 1986, The Journal of biological chemistry.

Multicenter assessment of CSF-phosphorylated tau for the prediction of conversion of MCI

K. Blennow, P. Scheltens, H. Hampel, 2007, Neurology.

Abbott-57219[SCH-40054]: A Novel Nasal Decongestant

J. Debernardis, R. Dudley, S. Buckner, 2007 .

A new nasal decongestant, A‐57219: a comparison with oxymetazoline

D. Kerkman, J. Debernardis, J. Kyncl, 1987, The Journal of pharmacy and pharmacology.

A simple and inexpensive method for the visual detection of sub-microgram amounts of halogenated substances present in gas chromatographic effluents.

J. Debernardis, J. Siuda, R. Cavestri, 1973, Journal of Chromatography A.

Synthesis of hexahydro‐5H‐benz[g]imidazo[2,1‐a]‐ isoindole 2 via an intramolecular diels‐alder reaction and a novel lawesson's reagent mediated cyclization

J. Debernardis, F. Basha, 1987 .

CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects

H. Arai, K. Blennow, H. Hampel, 2002, Neurology.

Longitudinal cerebrospinal fluid tau load increases in mild cognitive impairment

A. Convit, M. J. Leon, C. Tarshish, 2002, Neuroscience Letters.

Photoaffinity cross-linking of a radioiodinated probe, 125I-A55453, into alpha 1-adrenergic receptors.

M. Caron, J. Wikberg, R. Lefkowitz, 1984, Molecular pharmacology.

A FACILE SYNTHESIS OF DOPAMINE-4-SULFATE

D. Kerkman, J. Debernardis, S. Harbeson, 1983 .

Differentiation of geriatric major depression from Alzheimer's disease with CSF tau protein phosphorylated at threonine 231.

H. Möller, S. Rapoport, H. Hampel, 2003, The American journal of psychiatry.

Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231.

Katharina Buerger, Frank Padberg, Harald Hampel, 2002, Archives of neurology.

Alpha 2-adrenergic receptors and calcium: alpha 2-receptor blockade in vascular smooth muscle as an approach to the treatment of hypertension.

J. Debernardis, J. Y. Lee, 1990, Methods and Findings in Experimental and Clinical Pharmacology.

Discovery of a novel class of orally active, non-peptide angiotensin II antagonists.

D. Kerkman, J. Debernardis, A. Hancock, 1992, Journal of medicinal chemistry.

Adrenergic and Dopaminergic Properties of Dopamine Sulfoconjugates

D. Kerkman, E. Bush, J. Debernardis, 1985, Journal of cardiovascular pharmacology.

Conformationally defined adrenergic agents. 2. Catechol imidazoline derivatives: biological effects at alpha 1 and alpha 2 adrenergic receptors.

Y. Martin, D. Kerkman, J. Debernardis, 1986, Journal of Medicinal Chemistry.

Selective Alpha Adrenergic Agents – Differentiation of Receptor Subtypes

D. Kerkman, J. Debernardis, 1992 .

1,4-Addition of certain 2-lithio-1,3-dithianes to .alpha.,.beta.-unsaturated nitriles

S. Spanton, J. Debernardis, F. Basha, 1985 .

The structure of N-alkylidine-N-phenylnitrones

J. Debernardis, J. Baldwin, D. P. Kelly, 1969 .