K. Kosaka

K. Kosaka, K. Hasegawa, M. Murata, 2021, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

TAU-IMMUNOHISTOCHEMICAL AND -IMMUNOELECTRON MICROSCOPICAL INVESTIGATION OF ASTROCYTIC PLAQUES IN PROGRESSIVE SUPRANUCLEAR PALSY

Masanori Kato, H. Akiyama, K. Kosaka, 1997 .

IMMUNOHISTOCHEMICAL AND IMMUNOELECTRON MICROSCOPICAL INVESTIGATION OF TAU-POSITIVE NEURONS LACKING TANGLE-FORMATION IN PROGRESSIVE SUPRANUCLEAR PALSY

K. Kosaka, K. Ikeda, E. Iseki, 1998 .

Progressive supranuclear palsy with fronto-temporal atrophy and various tau-positive abnormal structures.

H. Akiyama, K. Kosaka, E. Iseki, 1996, Clinical neuropathology.

A novel missense mutation (G209R) in exon 8 of the presenilin 1 gene in a Japanese family with presenile familial Alzheimer's disease

Kyoko Suzuki, K. Kosaka, C. Kawanishi, 1999, Human mutation.

The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patients

K. Kosaka, K. Kobayashi, N. Iwamoto, 1989, Journal of Neurology.

Immunohistochemical localization of plasminogen activator inhibitor-1 in rat and human brain tissues

Masanori Kato, H. Akiyama, K. Kosaka, 2001, Neuroscience Letters.

A preliminary study of free amino acids in the postmorten temporal cortex from Alzheimer-type dementia patients

H. Arai, K. Kosaka, Y. Ichimiya, 1984, Neurobiology of Aging.

Ethnicity‐dependent genetic association of ABCA2 with sporadic Alzheimer's disease

M. Hersberger, M. Tsolaki, R. Nitsch, 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

6‐Pyruvoyl‐tetrahydropterin synthase deficiency with generalized dystonia and diurnal fluctuation of symptoms: A clinical and molecular study

T. Hanihara, H. Osaka, K. Kosaka, 1997, Movement disorders : official journal of the Movement Disorder Society.

Immunohistochemical study of tau accumulation in early stages of Alzheimer-type neurofibrillary lesions

A. Lees, R. Silva, H. Akiyama, 2004, Acta Neuropathologica.

Longitudinal study on MRI intensity changes of Machado–Joseph disease: correlation between MRI findings and neuropathological changes

Mari Yoshida, K. Kosaka, Y. Hashizume, 2011, Journal of Neurology.

[Some problems on the clinical phenotype of Machado-Joseph disease in relation between their ages at onset].

K. Kosaka, S. Yagishita, K. Ohtani, 1993, No to shinkei = Brain and nerve.

[Familial early onset cerebellar ataxia with hypoalbuminemia].

K. Kosaka, N. Sunohara, K. Iwabuchi, 1995, No to shinkei = Brain and nerve.

A patient with treatment‐resistant schizophrenia and cytochrome P4502D6 gene duplication

K. Kosaka, C. Kawanishi, T. Furuno, 2002, Clinical genetics.

Pelizaeus‐Merzbacher disease: Three novel mutations and implication for locus heterogeneity

I. Kanazawa, K. Fujii, S. Murayama, 1999, Annals of neurology.

H. Akiyama, K. Kosaka, K. Ikeda, 1996, Journal of the Neurological Sciences.

Ubiquitin-immunohistochemical investigation of atypical Pick's disease without Pick bodies

Masanori Kato, H. Akiyama, Kyoko Suzuki, 1998, Journal of the Neurological Sciences.

[A comparative study of Alzheimer's disease and Pick's disease by CT].

H. Arai, K. Kosaka, K. Kobayashi, 1984, Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.

Recent advances in dementia research in Japan: Non‐Alzheimer‐type degenerative dementias

K. Kosaka, E. Iseki, 1998, Psychiatry and clinical neurosciences.

Promoter polymorphism in fibroblast growth factor 1 gene increases risk of definite Alzheimer's disease.

T. Miki, S. Yokoyama, I. Kondo, 2004, Biochemical and biophysical research communications.

Cerebrospinal fluid manganese concentrations in patients with symmetric pallidal hyperintensities on T1 weighted MRI

K. Kosaka, S. Koyano, E. Iseki, 1999, Journal of neurology, neurosurgery, and psychiatry.

Transient lesion in the splenium of the corpus callosum, possibly due to carbamazepine

K. Kosaka, C. Kawanishi, T. Odawara, 2003, Psychiatry and clinical neurosciences.

Diffuse neurofibrillary tangles with calcification: a new presenile dementia.

K. Kosaka, 1994, Journal of neurology, neurosurgery, and psychiatry.

Occurrence of human alpha-synuclein immunoreactive neurons with neurofibrillary tangle formation in the limbic areas of patients with Alzheimer's disease.

K. Kosaka, E. Iseki, W. Marui, 2000, Journal of the neurological sciences.

Mutations in the Proteolipid Protein Gene in Japanese Families with Pelizaeus-Merzbacher Disease

H. Osaka, K. Kosaka, C. Kawanishi, 1997, Neurology.

Increasing in situ nick end labeling of oligodendrocytes in white matter of patients with Binswanger's disease.

Y. Nagai, R. Hata, K. Kosaka, 2001, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Serum ghrelin concentrations in patients receiving olanzapine or risperidone

K. Kosaka, E. Iseki, H. Uchikado, 2004, Psychopharmacology.

Morphometrical reappraisal of motor neuron system of Pick's disease and amyotrophic lateral sclerosis with dementia

H. Akiyama, K. Kosaka, K. Ikeda, 2002, Acta Neuropathologica.

A duplicated PLP gene causing Pelizaeus-Merzbacher disease detected by comparative multiplex PCR.

H. Osaka, K. Kosaka, C. Kawanishi, 1996, American journal of human genetics.

New point mutation (R301X) of the α‐galactosidase a gene causing fabry disease

T. Hanihara, H. Osaka, S. Kawamoto, 1995 .

Morphological and biochemical changes in the cholinergic and monoaminergic systems in Alzheimer-type dementia

H. Arai, K. Kosaka, Y. Ichimiya, 2004, Acta Neuropathologica.

Novel acceptor splice site mutation in the invariant AG of intron 6 of α‐galactosidase A gene, causing Fabry disease

H. Osaka, Kyoko Suzuki, K. Kosaka, 1998 .

Novel acceptor splice site mutation in the invariant AG of intron 6 of alpha-galactosidase A gene, causing Fabry disease. Mutations in brief no. 146. Online.

H. Osaka, K. Kosaka, C. Kawanishi, 1998, Human mutation.

Normal sequences of muscarinic acetylcholine receptors (m1 and m2) in patients with Alzheimer's disease and vascular dementia

K. Ohara, K. Kosaka, K. Ohara, 1994, Neuroscience Letters.

An immunohistochemical study of β-protein in Alzheimer-type dementia brains

H. Arai, K. Kosaka, S. Haga, 1989, Journal of Neurology.

Variations in the BDNF Gene in Autopsy-Confirmed Alzheimer’s Disease and Dementia with Lewy Bodies in Japan

S. Shimohama, I. Tooyama, M. Takeda, 2006, Dementia and Geriatric Cognitive Disorders.

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop.

K. Jellinger, D. Salmon, E. Perry, 1996, Neurology.

Clinicopathological multiplicity of dementia with Lewy bodies

Masanori Kato, K. Kosaka, Takayuki Yamamoto, 1999 .

Cerebral type of Lewy body disease

K. Kosaka, Takayuki Yamamoto, T. Odawara, 1996 .

Ultrastructural and immunohistochemical study of degenerate neurite-bearing ghost tangles

K. Ikeda, K. Kosaka, S. Oyanagi, 1992, Journal of Neurology.

An autopsied case of juvenile parkinsonism and dementia, with a widespread occurrence of Lewy bodies and spheroids.

K. Kosaka, K. Hasegawa, S. Yagishita, 1992, Clinical neuropathology.

A neuropathologic study of long‐term, Economo‐type postencephalitic parkinsonism with a prolonged clinical course

K. Mizukami, K. Kosaka, H. Shiraishi, 1996, Psychiatry and clinical neurosciences.

Expression of CD40 in the brain of Alzheimer’s disease and other neurological diseases

Masanori Kato, H. Akiyama, K. Kosaka, 2000, Brain Research.

Hereditary multisystemic degeneration with unusual combination of cerebellipetal, dentato-rubral, and nigro-subthalamo-pallidal degenerations.

T. Mizutani, M. Oda, K. Kosaka, 1983, Clinical neuropathology.

DLB and PDD boundary issues

D J Brooks, J Q Trojanowski, S Fahn, 2007, Neurology.

A non-alcoholic Japanese patient with Wernicke's encephalopathy and Marchiafava-Bignami disease.

K. Kosaka, Y. Adachi, R. Iizuka, 1984, Clinical neuropathology.

Neuronal accumulation of alpha- and beta-synucleins in the brain of a GM2 gangliosidosis mouse model.

I. Aoki, Kyoko Suzuki, A. Yamaguchi, 2003, Neuroreport.

Staining senile plaques using Bodian's method modified with methenamine.

K. Kosaka, M. Matsushita, N. Miyazaki, 1993, Biotechnic & histochemistry : official publication of the Biological Stain Commission.

Dementia with Lewy Bodies: Diffuse Lewy body disease within the spectrum of Lewy body disease

K. Kosaka, E. Iseki, 1996 .

Pallido-nigro-luysial atrophy with massive appearance of corpora amylacea in the CNS

S. Uchiyama, K. Kosaka, M. Matsushita, 2004, Acta Neuropathologica.

Japanese Creutzfeldt-Jakob disease patients exhibiting high incidence of the E200K PRNP mutation and located in the basin of a river.

K. Kosaka, C. Kawanishi, E. Iseki, 1998, Neurological research.

Dementia and neuropathology in Lewy body disease.

K. Kosaka, 1993, Advances in neurology.

[A computed tomography study of Pick's disease].

H. Arai, K. Kosaka, K. Kobayashi, 1984, Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.

Extrahypophyseal distribution of α-melanocyte stimulating hormone (α-MSH)-like immunoreactivity in postmortem brains from normal subjects and Alzheimer-type dementia patients

H. Arai, K. Kosaka, T. Moroji, 1986, Brain Research.

Depletion of cholinergic neurons in the nucleus of the medial septum and the vertical limb of the diagonal band in dementia with Lewy bodies

A. Iguchi, H. Umegaki, H. Fujishiro, 2006, Acta Neuropathologica.

Extrahypophyseal distribution of alpha-melanocyte stimulating hormone (alpha-MSH)-like immunoreactivity in postmortem brains from normal subjects and Alzheimer-type dementia patients.

H. Arai, K. Kosaka, T. Moroji, 1986, Brain research.

Methamphetamine in Japan: the consequences of methamphetamine abuse as a function of route of administration.

K. Kosaka, E. Iseki, Keiko Endo, 2002, Addiction.

Anti-ganglioside GD1a monoclonal antibody recognizes senile plaques in the brains of patients with Alzheimer-type dementia

Yasuo Suzuki, K. Kosaka, S. Shimada, 1993, Neuroscience Research.

Nasu-Hakola's disease (membranous lipodystrophy)

K. Kosaka, M. Matsushita, S. Oyanagi, 1981, Acta Neuropathologica.

THE SELECTION OF TEST MATERIALS AND THE REVISION OF THE COLLECTION'S METHOD OF MURINE LEPROSY BACILLUS FOR ITS METABOLIC INVESTIGATIONS: For Basic Studies on Cultivation of the Human and Murine Leprosy Bacilli (1)@@@癩菌,鼠癩菌の培養に関連した基礎的研究(1)

K. Kosaka, Tatsuo Mori, S. Nishimura, 1961 .

Alterations of muscarinic acetylcholine receptor subtypes in diffuse Lewy body disease: relation to Alzheimer’s disease

K. Kameyama, T. Haga, K. Kosaka, 1999, Journal of neurology, neurosurgery, and psychiatry.

Membrane Topology of Alzheimer’s Disease-related Presenilin 1

Toshiki Nakai, Masao Sakaguchi, Kenji Kosaka, 1999, The Journal of Biological Chemistry.

Concurrence of TDP-43, tau and α-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies

H. Arai, K. Kosaka, R. Yamamoto, 2007, Brain Research.

Autopsy case of concurrent Huntington's disease and neurofibromatosis type 1

Y. Hirayasu, H. Akiyama, Kyoko Suzuki, 2014, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

Diagnosis and management of dementia with Lewy bodies

S Minoshima, J Q Trojanowski, J Hardy, 2005, Neurology.

Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases

Masanori Kato, H. Akiyama, K. Kosaka, 2002, Journal of Neuroimmunology.

Abnormal Localization of Leucine-Rich Repeat Kinase 2 to the Endosomal-Lysosomal Compartment in Lewy Body Disease

P. Emson, K. Wada, T. Dawson, 2009, Journal of neuropathology and experimental neurology.

A novel mutation found in an adrenoleukodystrophy patient who underwent bone marrow transplantation

Y. Sakakihara, A. Oka, H. Osaka, 1998, Journal of Inherited Metabolic Disease.

Activation of vascular endothelial cells and perivascular cells by systemic inflammation—an immunohistochemical study of postmortem human brain tissues

Masanori Kato, H. Akiyama, K. Kosaka, 2004, Acta Neuropathologica.

Endoscopic Findings of the Upper Digestive Tract in Patients with Pancreatic Cancer

K. Fujimori, K. Kosaka, K. Fujiwara, 1995 .

123I-MIBG myocardial scintigraphy for the diagnosis of DLB: a multicentre 3-year follow-up study

T. Asada, T. Tokuda, K. Nakashima, 2018, Journal of Neurology, Neurosurgery, and Psychiatry.

[A new type of complicated form of hereditary spastic paraplegia showing mental deterioration, quadriplegia with muscular atrophy, sensory disturbance, extrapyramidal disorders, and epilepsy].

K. Kosaka, S. Yagishita, K. Iwabuchi, 1991, Rinsho shinkeigaku = Clinical neurology.

[An autopsy case of complicated form of spastic paraplegia with amyotrophy, mental deficiency, sensory impairment, and parkinsonism].

K. Kosaka, S. Yagishita, K. Iwabuchi, 1990, No to shinkei = Brain and nerve.

Intraneuronal Polyglucosan Bodies and Peculiar Inclusions in the Midbrain‐Tegmentum of the Aged

K. Kosaka, K. Ikeda, A. Hori, 1987, The Japanese journal of psychiatry and neurology.

Novel nonsense proteolipid protein gene mutation as a cause of X-linked spastic paraplegia in twin males.

H. Osaka, K. Kosaka, C. Kawanishi, 1995, Biochemical and biophysical research communications.

A new restriction-site polymorphism in the human proteolipid protein gene.

H. Osaka, K. Kosaka, C. Kawanishi, 2008, Clinical genetics.

Pelizaeus‐Merzbacher disease: A novel mutation in the 5′‐untranslated region of the proteolipid protein gene

H. Osaka, Kyoko Suzuki, K. Kosaka, 1996, Human mutation.

Regional distribution of amino acid transmitters in postmortem brains of presenile and senile dementia of Alzheimer type

I. Kanazawa, H. Arai, H. Sasaki, 1986, Annals of neurology.

Progressive myoclonus epilepsy with unusual neuropathologic features

K. Mizukami, K. Kosaka, H. Shiraishi, 1995 .

Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies

A. Nunomura, A. Takeda, R. Castellani, 2002, Neuroreport.

A novel membrane protein, encoded by the gene covering KIAA0233, is transcriptionally induced in senile plaque-associated astrocytes

K. Kosaka, H. Yokota, Tatsuo Yamada, 2006, Brain Research.

Frequency and distribution of TUNEL‐positive neurons in brains of dementia with Lewy bodies: Comparison with those in brains of Alzheimer's disease

Kyoko Suzuki, K. Kosaka, E. Iseki, 2001, Neuropathology : official journal of the Japanese Society of Neuropathology.

Progression and staging of Lewy pathology in brains from patients with dementia with Lewy bodies

Toshiki Nakai, Kenji Kosaka, Masanori Kato, 2002, Journal of the Neurological Sciences.

System degeneration of the thalamus

K. Kosaka, K. Ikeda, A. Hori, 2004, Archiv für Psychiatrie und Nervenkrankheiten.

Clinical Aspects of ‘Senile Dementia of the Tangle Type’ – A Subset of Dementia in the Senium Separable from Late-Onset Alzheimer’s Disease

Masanori Kato, H. Akiyama, Hitoshi Takahashi, 1998, Dementia and Geriatric Cognitive Disorders.

Combined Supranuclear Horizontal and Vertical Gaze Palsy in a Bilateral Thalamic Infarction

J. Yokota, K. Kosaka, T. Amakusa, 1999 .

Clinical profiles of autopsy‐confirmed dementia with Lewy bodies at institutionalization: Comparison with Alzheimer’s disease

A. Iguchi, H. Umegaki, H. Fujishiro, 2007 .

Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ1–42) to Aβ1–40, and Its Inhibition Enhances Brain Aβ Deposition

K. Zou, M. Michikawa, H. Yamaguchi, 2007, The Journal of Neuroscience.

Changes of Biogenic Amines and Their Metabolites in Postmortem Brains from Patients with Alzheimer‐Type Dementia

K. Kosaka, R. Iizuka, H. Aral, 1984, Journal of neurochemistry.

SORL1 is genetically associated with neuropathologically characterized late-onset Alzheimer's disease.

N. Kitamura, A. Kakita, A. Miyashita, 2013, Journal of Alzheimer's disease : JAD.

Increased incidence of dementia with Lewy bodies in patients carrying the ɛ4‐allele of apolipoprotein E

M. Takeda, T. Miki, I. Kondo, 2004 .

Brain site‐specific gene expression analysis in Alzheimer's disease patients

K Kosaka, Y. Nagai, K. Kosaka, 2006, European journal of clinical investigation.

Dementia with Lewy bodies showing advanced Lewy pathology but minimal Alzheimer pathology--Lewy pathology causes neuronal loss inducing progressive dementia.

K. Kosaka, E. Iseki, H. Uchikado, 2002, Clinical neuropathology.

Mitsugumin 29 is transcriptionally induced in senile plaque-associated astrocytes

K. Kosaka, H. Yokota, Tatsuo Yamada, 2012, Brain Research.

Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix.

K. Kosaka, H. Yokota, Tatsuo Yamada, 2005, Biochemical and biophysical research communications.

Immunohistochemical study of the expression of cytokines and nitric oxide synthases in brains of patients with dementia with Lewy bodies

K. Kosaka, E. Iseki, O. Katsuse, 2003, Neuropathology : official journal of the Japanese Society of Neuropathology.

Degeneration of Pick bodies visualized by methenamine‐silver staining and immunohistochemistry

Kyoko Suzuki, K. Kosaka, T. Odawara, 2002, Neuropathology : official journal of the Japanese Society of Neuropathology.

Diffuse Lewy body disease.

K. Kosaka, Kenji Kosaka, 1998, Internal medicine.

Prolactin levels in schizophrenic patients receiving perospirone in comparison to risperidone.

K. Kosaka, E. Iseki, H. Uchikado, 2003, Journal of pharmacological sciences.

Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) and diabetes mellitus: molecular genetic analysis and family study

T. Hanihara, H. Osaka, S. Kawamoto, 1993, Journal of the Neurological Sciences.

The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.

T. Uema, T. Kudo, H. Kazui, 2007, Human molecular genetics.

Immunohistochemical investigation of neurofibrillary tangles and their tau isoforms in brains of limbic neurofibrillary tangle dementia

H. Akiyama, H. Arai, K. Kosaka, 2006, Neuroscience Letters.

Relationship in the formation process between neurofibrillary tangles and Lewy bodies in the hippocampus of dementia with Lewy bodies brains

K. Kosaka, E. Iseki, W. Marui, 2002, Journal of the Neurological Sciences.

Dementia with Lewy bodies.

K. Kosaka, E. Iseki, 1996, Current opinion in neurology.

Cognitive conditions of pathologically confirmed dementia with Lewy bodies and Parkinson's disease with dementia

K. Kosaka, H. Akatsu, Takayuki Yamamoto, 2003, Journal of the Neurological Sciences.

Central nervous system changes in mitochondrial encephalomyopathy: light and electron microscopic study

K. Mizukami, K. Kosaka, Toshihito Suzuki, 2004, Acta Neuropathologica.

Long-term donepezil use for dementia with Lewy bodies: results from an open-label extension of Phase III trial

E. Mori, M. Ikeda, K. Kosaka, 2015, Alzheimer's Research & Therapy.

Long-Term Safety and Efficacy of Donepezil in Patients with Dementia with Lewy Bodies: Results from a 52-Week, Open-Label, Multicenter Extension Study

E. Mori, M. Hashimoto, M. Ikeda, 2013, Dementia and Geriatric Cognitive Disorders.

Donepezil for Dementia with Lewy Bodies: A Randomized, Placebo-Controlled Trial

E. Mori, M. Ikeda, K. Kosaka, 2012, Annals of neurology.

Localization of serotonin immunoreactivity in cephalopod visual system

K. Kosaka, C. Haga, H. Kondo, 1990, Brain Research.

No evidence of an association between CYP2D6 polymorphisms among Japanese and dementia with Lewy bodies

Kyoko Suzuki, K. Kosaka, C. Kawanishi, 2001, Psychiatry and clinical neurosciences.

Diagnostic Accuracy of 123I-Meta-Iodobenzylguanidine Myocardial Scintigraphy in Dementia with Lewy Bodies: A Multicenter Study

T. Asada, E. Mori, T. Tokuda, 2015, PloS one.

When does cerebral β‐amyloid deposition begin in Lewy body dementia?

H. Fujishiro, K. Kosaka, 2020 .

Regional quantitative analysis of NFT in brains of non‐demented elderly persons: Comparisons with findings in brains of late‐onset Alzheimer’s disease and limbic NFT dementia

Kyoko Suzuki, K. Kosaka, H. Akatsu, 2002, Neuropathology : official journal of the Japanese Society of Neuropathology.

Diffuse neurofibrillary tangles with calcification (Kosaka–Shibayama disease) in Japan

K. Kosaka, K. Ukai, 2016, Psychiatry and clinical neurosciences.

Response to ‘Challenging the concept of diffuse neurofibrillary tangles with calcification (Kosaka–Shibayama disease)’

K. Kosaka, 2017, Psychiatry and clinical neurosciences.

Diffuse neurofibrillary tangles with calcification in a non-demented woman.

K. Kosaka, K. Ikeda, 1996, Journal of neurology, neurosurgery, and psychiatry.

Distribution and morphology of brain stem plaques in Alzheimer's disease

K. Kosaka, K. Kosaka, H. Kondo, 2004, Acta Neuropathologica.

Latest concept of Lewy body disease

K. Kosaka, 2014, Psychiatry and clinical neurosciences.

Neuropathological study of the amygdala in presenile Alzheimer's disease

K. Kosaka, K. Tsuchiya, 1990, Journal of the Neurological Sciences.

Striatopallidonigral degeneration in Pick's disease: a clinicopathological study of 41 cases

K. Kosaka, K. Kobayashi, K. Ikeda, 1991, Journal of Neurology.

Neuropathological investigation of hypocretin expression in brains of dementia with Lewy bodies

H. Arai, H. Fujishiro, K. Kosaka, 2014, Neuroscience Letters.

Localization of MAP1-LC3 in Vulnerable Neurons and Lewy Bodies in Brains of Patients With Dementia With Lewy Bodies

K. Wada, H. Arai, Tomohiro Kabuta, 2011, Journal of neuropathology and experimental neurology.

Clinical features of argyrophilic grain disease: a retrospective survey of cases with neuropsychiatric symptoms.

Y. Hirayasu, Kyoko Suzuki, K. Kosaka, 2005, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Appearance pattern of TDP-43 in Japanese frontotemporal lobar degeneration with ubiquitin-positive inclusions

H. Arai, K. Kosaka, R. Yamamoto, 2007, Neuroscience Letters.

Neuropathological Investigation of Regions Responsible for Semantic Aphasia in Frontotemporal Lobar Degeneration

Mari Yoshida, Shinji Higashi, Kenji Kosaka, 2009, Dementia and Geriatric Cognitive Disorders.

Donepezil for dementia with Lewy bodies: a randomized, placebo-controlled, confirmatory phase III trial

E. Mori, M. Ikeda, K. Kosaka, 2015, Alzheimer's Research & Therapy.

Peculiar axonal debris with subsequent astrocytic response (foamy spheroid body)

T. Mizutani, M. Oda, K. Kosaka, 1992, Virchows Archiv A.

Occurrence of human α-synuclein immunoreactive neurons with neurofibrillary tangle formation in the limbic areas of patients with Alzheimer’s disease

K. Kosaka, E. Iseki, W. Marui, 2000, Journal of the Neurological Sciences.

Alterations of muscarinic acetylcholine receptors in atypical Pick’s disease without Pick bodies

K. Kosaka, T. Odawara, E. Iseki, 2003, Journal of neurology, neurosurgery, and psychiatry.

[A clinicopathological study of Pick's disease--our sixty autopsied cases (author's transl)].

K. Kosaka, P. Mehraein, M. Matsushita, 1982, Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.

Clinicopathological Study of Two Subtypes of Pick’s Disease in Japan

Masanori Kato, K. Kosaka, Takayuki Yamamoto, 2002, Dementia and Geriatric Cognitive Disorders.

Decreased ventilatory response to hypercapnia in dementia with Lewy bodies

T. Asada, K. Aonuma, T. Kinoshita, 2009, Annals of neurology.

Pathological entity of dementia with Lewy bodies and its differentiation from Alzheimer’s disease

Masanori Kato, K. Kosaka, H. Akatsu, 2004, Acta Neuropathologica.

Distribution of m1 muscarinic acetylcholine receptors in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies—an immunohistochemical study

K. Kosaka, E. Iseki, K. Shiozaki, 2001, Journal of the Neurological Sciences.

Detection of Neurofibrillary Tangles by the Methenamine‐Silver Method: Comparison with Other Silver Stains and with Immunostaining Methods

H. Akiyama, K. Kosaka, K. Ikeda, 1993 .

Methenamine-silver staining: a simple and sensitive staining method for senile plaques and neurofibrillary tangles.

H. Akiyama, K. Kosaka, K. Ikeda, 1994, Biotechnic & histochemistry : official publication of the Biological Stain Commission.

Incidence and Distribution of Senile Plaques and Neurofibrillary Tangles in Late‐onset Diffuse Lewy Body Disease

K. Kosaka, K. Ikeda, T. Odawara, 1994 .

A computed tomography study of Alzheimer's disease by regional volumetric and parenchymal density measurements

H. Arai, K. Kosaka, K. Kobayashi, 1986, Journal of Neurology.

A computed tomography study of Alzheimer's disease

K. Kosaka, H. Arai, K. Kosaka, 2004, Journal of Neurology.

Masako Watanabe, N. Ozaki, H. Fujishiro, 2017, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

Quantitative EEG in patients with presenile and senile dementia of the Alzheimer type

K Kosaka, K. Kosaka, T Miyauchi, 1994, Acta neurologica Scandinavica.

Parvalbumin-immunoreactive neurons in the cortex in Pick's disease

C. Heizmann, H. Arai, K. Kosaka, 1991, Journal of Neurology.

Reduction of telencephalin immunoreactivity in the brain of patients with Alzheimer's disease

K. Mori, Y. Yoshihara, H. Akiyama, 1997, Brain Research.

[Distribution of Pick bodies in the central nervous system of Pick's disease with special reference to their association with neuronal loss].

K. Arima, K. Kosaka, M. Matsushita, 1987, Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.

Neuropathological investigation of the hypometabolic regions on positron emission tomography with ( 18 F) fluorodeoxyglucose in patients with dementia

H. Arai, H. Fujishiro, K. Kosaka, 2012 .

Adequacy of Using Consensus Guidelines for Diagnosis of Dementia with Lewy Bodies in Clinical Trials for Drug Development

E. Mori, M. Hashimoto, M. Ikeda, 2015, Dementia and Geriatric Cognitive Disorders.

Correlation in Lewy pathology between the claustrum and visual areas in brains of dementia with Lewy bodies

Masanori Kato, T. Iwatsubo, H. Arai, 2007, Neuroscience Letters.

Investigation of Lewy pathology in the visual pathway of brains of dementia with Lewy bodies

Masanori Kato, T. Iwatsubo, H. Arai, 2006, Journal of the Neurological Sciences.

[Kosaka's disease].

K. Kosaka, 2008, Brain and nerve = Shinkei kenkyu no shinpo.

A manic episode associated with bereavement in a patient with lung cancer

K. Kosaka, A. Miyashita, H. Onishi, 2000, Supportive Care in Cancer.

Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia

H. Arai, H. Fujishiro, K. Kosaka, 2010, Neuroscience Letters.

Efficacy and safety of donepezil in patients with dementia with Lewy bodies: Preliminary findings from an open‐label study

E. Mori, K. Kosaka, E. Iseki, 2006, Psychiatry and clinical neurosciences.

A novel alternative splice variant of nicastrin and its implication in Alzheimer disease.

M. Takeda, T. Miki, I. Kondo, 2006, Life sciences.

Selective loss of nigral neurons in Alzheimer's disease: a morphometric study

K. Kosaka, T. Uchihara, H. Tsukagoshi, 2004, Acta Neuropathologica.

Mval polymorphism in the proteolipid protein (PLP) gene

H. Osaka, Kyoko Suzuki, K. Kosaka, 1995, Human Genetics.

A neuropathological study of the disturbance of the nigro-amygdaloid connections in brains from patients with dementia with Lewy bodies

Kenji Kosaka, Masanori Kato, K. Kosaka, 2001, Journal of the Neurological Sciences.

Hippocampal pathology in diffuse Lewy body disease using ubiquitin immunohistochemistry

K. Kosaka, T. Odawara, E. Iseki, 1997, Journal of the Neurological Sciences.

Evaluation of Neuropathological Stages Based on Quantification of Senile Changes in Non‐Demented Elderly Individuals and Alzheimer‐Type Dementia

K. Kosaka, K. Ikeda, T. Odawara, 1993 .

TAFI polymorphisms at amino acids 147 and 325 are not risk factors for cerebral infarction

M. Takeda, T. Miki, I. Kondo, 2004, British journal of haematology.

Effects of Donepezil on Extrapyramidal Symptoms in Patients with Dementia with Lewy Bodies: A Secondary Pooled Analysis of Two Randomized-Controlled and Two Open-Label Long-Term Extension Studies

E. Mori, M. Ikeda, K. Kosaka, 2015, Dementia and Geriatric Cognitive Disorders.

Selective loss of nigral neurons in Pick's disease: a morphometric study

T. Uchihara, K. Kosaka, K. Tsuchiya, 2004, Acta Neuropathologica.

Alzheimer-type pathology in melanin-bleached sections of substantia nigra

T. Uchihara, K. Kosaka, K. Ikeda, 1995, Journal of Neurology.

Distinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain

S. Hirai, H. Yamaguchi, K. Kosaka, 2004, Acta Neuropathologica.

Subtype analysis of neuropathologically diagnosed patients in a Japanese geriatric hospital

H. Okada, N. Matsukawa, K. Kosaka, 2002, Journal of the Neurological Sciences.

Lewy bodies in cerebral cortex. Report of three cases

Kenji Kosaka, K. Kosaka, 1978, Acta Neuropathologica.

Immunohistochemical study of synphilin-1 in brains of patients with dementia with Lewy bodies – synphilin-1 is non-specifically implicated in the formation of different neuronal cytoskeletal inclusions

K. Kosaka, E. Iseki, W. Marui, 2002, Neuroscience Letters.

Diffuse Lewy body disease

K. Kosaka, Kenji Kosaka, 2000, Neuropathology : official journal of the Japanese Society of Neuropathology.

Diffuse Lewy body disease.

K. Kosaka, 1995, Internal medicine.

[Amyotrophic lateral sclerosis with degeneration of thalamus and substantia nigra (author's transl)].

K. Kosaka, P. Mehraein, 1978, Acta neuropathologica.

Lewy body disease and dementia with Lewy bodies

K. Kosaka, 2014, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

Non‐uniformity in the regional pattern of Lewy pathology in brains of dementia with Lewy bodies

Masanori Kato, H. Arai, K. Kosaka, 2005, Neuropathology : official journal of the Japanese Society of Neuropathology.

Dementia-parkinsonism syndrome with numerous lewy bodies and senile plaques in cerebral cortex

K. Kosaka, P. Mehraein, 1979, Archiv für Psychiatrie und Nervenkrankheiten.

History and Latest Concepts of Lewy Body Disease and Dementia with Lewy Bodies

K. Kosaka, 2017 .

FROM THE PROPOSAL OF LEWY BODY DISEASE TO THE PROPOSAL OF DIFFUSE LEWY BODY DISEASE

K. Kosaka, 2014 .

Dementia with Lewy Bodies and Parkinson Disease with Dementia Within the Spectrum of Lewy Body Disease

K. Kosaka, 2010 .

[Dementia with Lewy bodies--from its finding to the present, including the CDLB guideline-revised].

K. Kosaka, 2007, Rinsho shinkeigaku = Clinical neurology.

Behavioral and Psychological Symptoms of Dementia

K. Kosaka, Y. Manabe, 2017 .

Iodobenzylguanidine Myocardial Scintigraphy in Dementia with Lewy Bodies

T. Asada, E. Mori, T. Tokuda, 2015 .

Effect of zonisamide on parkinsonism in patients with dementia with Lewy bodies: A phase 3 randomized clinical trial.

K. Kosaka, K. Hasegawa, M. Murata, 2019, Parkinsonism & related disorders.

Multiple system degeneration involving thalamus, reticular formation, pallido-nigral, pallido-Luysian and dentato-rubral systems

K. Kosaka, A. Hori, M. Matsushita, 1977, Acta Neuropathologica.

Evaluation of Probable or Possible Dementia with Lewy Bodies Using 123 I-IMP Brain Perfusion SPECT, 123 I-MIBG, and 99m Tc-MIBI

K. Katada, H. Toyama, M. Sarai, 2007 .

Dynamin 2 gene is a novel susceptibility gene for late-onset Alzheimer disease in non-APOE-ε4 carriers

T. Uema, T. Kudo, H. Kazui, 2008, Journal of Human Genetics.

Psychiatric symptoms typical of patients with dementia with Lewy bodies – similarity to those of levodopa-induced psychosis

K. Kosaka, E. Iseki, W. Marui, 2002, Acta Neuropsychiatrica.

Vascular complications in dementia with Lewy bodies: A postmortem study

Y. Hirayasu, H. Fujishiro, K. Kosaka, 2006, Neuropathology : official journal of the Japanese Society of Neuropathology.

Pretreatment Cognitive Profile Likely to Benefit from Donepezil Treatment in Dementia with Lewy Bodies: Pooled Analyses of Two Randomized Controlled Trials

E. Mori, M. Ikeda, K. Kosaka, 2016, Dementia and Geriatric Cognitive Disorders.

[Pick's disease with concomitant traumatic brain damage--five autopsied cases and a critical review of literatures (author's transl)].

K. Kosaka, P. Mehraein, M. Matsushita, 1980, Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.

Psychomotor retardation correlates with frontal hypoperfusion and the Modified Stroop Test in patients with major depression under 60‐years‐old

Hiroyuki Narita, Yoshio Hirayasu, Kenji Kosaka, 2004 .

Psychomotor retardation correlates with frontal hypoperfusion and the Modified Stroop Test in patients under 60-years-old with major depression.

Y. Hirayasu, K. Kosaka, T. Odawara, 2004, Psychiatry and clinical neurosciences.

Senile plaque-like structures: observation of a probably unknown type of senile plaque by periodic-acid methenamine silver (PAM) electron microscopy

K. Kosaka, K. Ikeda, S. Oyanagi, 2004, Acta Neuropathologica.

Light and Electron Microscopic Observations of Diffuse Plaque and Its Related Conditions

K. Kosaka, K. Ikeda, C. Haga, 1990 .

Light and electron microscopic examination of amyloid-rich primitive plaques: comparison with diffuse plaques

K. Kosaka, K. Ikeda, C. Haga, 1990, Journal of Neurology.

A Clinicopathological Study of Idiopathic Normal Pressure Hydrocephalus

N. Matsukawa, K. Kosaka, K. Ojika, 2002 .

Depressive disorder due to mitochondrial transfer RNALeu(UUR) mutation

T. Hanihara, H. Osaka, K. Kosaka, 1997, Biological Psychiatry.

Neuroleptic malignant syndrome and hydroxylase gene mutations: no association with CYP2D6A or CYP2D6B

T. Hanihara, K. Kosaka, C. Kawanishi, 1997, Psychiatric genetics.

Adult type of neuronal ceroid-lipofuscinosis with retinal involvement.

K. Kosaka, K. Ikeda, S. Oyanagi, 1984, Clinical neuropathology.

Characterizing CGI‐94 (comparative gene identification‐94) which is down‐regulated in the hippocampus of early stage Alzheimer's disease brain

Y. Nagai, R. Hata, K. Kosaka, 2002, The European journal of neuroscience.

Neuropathological evaluation and apolipoprotein E gene polymorphism analysis in diffuse Lewy body disease

Kyoko Suzuki, K. Kosaka, Takayuki Yamamoto, 1996, Journal of the Neurological Sciences.

A Combination of Alzheimer's and Binswanger's Diseases —A Clinicopathological Study of Four Cases—

K. Kosaka, K. Ikeda, M. Matsushita, 1986, The Japanese journal of psychiatry and neurology.

Regional quantitative study of formation process of neurofibrillary tangles in the hippocampus of non‐demented elderly brains: Comparison with late‐onset Alzheimer's disease brains

K. Kosaka, Takayuki Yamamoto, E. Iseki, 2002, Neuropathology : official journal of the Japanese Society of Neuropathology.

Post-traumatic stress disorder associated with suspected lung cancer and bereavement: 4-year follow-up and review of the literature

K. Kosaka, Tomoki Yamada, Hideki Onishi, 2003, Supportive Care in Cancer.

[A biochemical study of cholinergic neurons of the post-mortem brains from the patients with Alzheimer-type dementia].

K Kosaka, H. Arai, K. Kosaka, 1984, Rinsho shinkeigaku = Clinical neurology.

Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

J. Haines, M. Pericak-Vance, G. Schellenberg, 2013, PLoS ONE.

Characterizing the new transcription regulator protein p60TRP

Y. Nagai, K. Kosaka, K. Heese, 2004, Journal of cellular biochemistry.

Clinical and genetic evaluation of Japanese autosomal dominant cerebellar ataxias; is Machado-Joseph disease common in the Japanese?

T. Hanihara, K. Kosaka, K. Iwabuchi, 1996, Journal of neurology, neurosurgery, and psychiatry.

Gray matter lesions in Nasu‐Hakola disease: A report on three autopsy cases

Y. Hirayasu, H. Akiyama, Kyoko Suzuki, 2011, Neuropathology : official journal of the Japanese Society of Neuropathology.

Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia

H. Arai, H. Fujishiro, K. Kosaka, 2010, Neuroscience Letters.

[A Japanese family with familial Alzheimer's disease associated with presenilin 1 mutation: relationship between younger age of onset and ApoE gene polymorphism].

Kyoko Suzuki, K. Kosaka, T. Odawara, 2003, No to shinkei = Brain and nerve.

Lymphocyte-specific protein tyrosine kinase is a novel risk gene for Alzheimer disease

M. Takeda, T. Miki, I. Kondo, 2005, Journal of the Neurological Sciences.

Psychiatric symptoms typical of patients with dementia with Lewy bodies – similarity to those of levodopa-induced psychosis

K. Kosaka, E. Iseki, W. Marui, 2002, Acta Neuropsychiatrica.

Pick's Disease and Head Trauma

K. Kosaka, P. Mehraein, M. Matsushita, 1982, Folia psychiatrica et neurologica japonica.

An Autopsied Case of Dentatorubropallidoluysian Atrophy with Atypical Pathological Features

K. Mizukami, K. Kosaka, J. Koizumi, 1992, The Japanese journal of psychiatry and neurology.

Mitsugumin 29 is transcriptionally induced in senile plaque-associated astrocytes

K. Kosaka, H. Yokota, Tatsuo Yamada, 2012, Brain Research.