R. Dolle

发表

A statistical-based approach to assessing the fidelity of combinatorial libraries encoded with electrophoric molecular tags. Development and application of tag decode-assisted single bead LC/MS analysis.

W. Egan, J. Reader, M. Orlowski, 2000, Journal of combinatorial chemistry.

Comprehensive survey of combinatorial library synthesis: 2000.

R. Dolle, 2001, Journal of combinatorial chemistry.

Comprehensive survey of combinatorial library synthesis: 2005.

J. Salvino, R. Dolle, B. Le Bourdonnec, 2006, Journal of combinatorial chemistry.

Arylacetamide κ opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity

R. Dolle, J. Cassel, R. Susnow, 2005 .

Discovery of enzyme inhibitors through combinatorial chemistry

R. Dolle, 2005, Molecular Diversity.

Solid-phase synthesis of α-hydroxy phosphonates and hydroxystatine amides. Transition-state isosteres derived from resin-bound amino acid aldehydes

R. Dolle, T. Herpin, Y. Shimshock, 2001 .

Comprehensive survey of combinatorial library synthesis: 1998.

R. Dolle, R E Dolle, K. Nelson, 1999, Journal of combinatorial chemistry.

Comprehensive Survey of Combinatorial Library Synthesis: 1998

R. Dolle, K. Nelson, 2010 .

Small molecule biaryl FSH receptor agonists. Part 1: Lead discovery via encoded combinatorial synthesis.

M. Webb, R. Dolle, T. Guo, 2004, Bioorganic & medicinal chemistry letters.

Comprehensive survey of combinatorial library synthesis: 2004.

R. Dolle, 2005, Journal of combinatorial chemistry.

Comprehensive Survey of Combinatorial Library Synthesis: 2004

R. Dolle, 2006 .

Role of Chemistry in Lead Discovery

R. Dolle, Karin Worm, 2010 .

Discovery of a series of aminopiperidines as novel iNOS inhibitors.

R. Dolle, L. Leister, J. Cassel, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of diacylhydrazines as inhibitors of the interleukin-1β converting enzyme (ICE)

T. Graybill, R. Dolle, M. Ator, 1995 .

Structural and stereochemical requirements of time-dependent inactivators of the interleukin-1β converting enzyme

Robert E. Miller, T. Graybill, C. Prouty, 1995 .

Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor.

D. Hoyer, T. Graybill, C. Prouty, 1997, Journal of medicinal chemistry.

Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.

S. Bevan, H. Gstach, Viral Patel, 2009, Bioorganic & medicinal chemistry letters.

Comprehensive survey of combinatorial library synthesis: 2001.

R. Dolle, 2002, Journal of combinatorial chemistry.

The selective mu‐opioid receptor antagonist adl5510 reduces levodopa‐induced dyskinesia without affecting antiparkinsonian action in mptp‐lesioned macaque model of Parkinson's disease

J. Brotchie, S. Fox, T. H. Johnston, 2011, Movement disorders : official journal of the Movement Disorder Society.

Solid/solution-phase annulation reagents: single-step synthesis of cyclic amine derivatives.

T. Herbertz, C. Macleod, R. Dolle, 2005, Angewandte Chemie.

α-((Tetronoyl)oxy)- and α-((tetramoyl)oxy)methyl ketone inhibitors of the interleukin-1β converting enzyme (ICE)

T. Graybill, C. Prouty, R. Dolle, 1997 .

Preparation and evaluation of peptidic aspartyl hemiacetals as reversible inhibitors of interleukin-1 beta converting enzyme (ICE).

T. Graybill, R. Dolle, M. Ator, 2009, International journal of peptide and protein research.

P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme.

D. Hoyer, R. Dolle, M. Ator, 1994, Journal of medicinal chemistry.

Aspartyl alpha-((diphenylphosphinyl)oxy)methyl ketones as novel inhibitors of interleukin-1 beta converting enzyme. Utility of the diphenylphosphinic acid leaving group for the inhibition of cysteine proteases.

T. Graybill, R. Dolle, D. Whipple, 1995, Journal of medicinal chemistry.

Aspartyl alpha-((1-phenyl-3-(trifluoromethyl)-pyrazol-5-yl)oxy)methyl ketones as interleukin-1 beta converting enzyme inhibitors. Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding.

D. Hoyer, T. Graybill, J. Salvino, 1994, Journal of medicinal chemistry.

Opioid Receptor Antagonists for Gastrointestinal Dysfunction

R. Dolle, R. W. Hipkin, R. Hipkin, 2010 .

The Discovery and Development of the N‐Substituted trans‐3,4‐Dimethyl‐4‐(3′‐hydroxyphenyl)piperidine Class of Pure Opioid Receptor Antagonists

F. Carroll, R. Dolle, 2014, ChemMedChem.

Pharmacology and structure--activity relationships of the nonpeptide bradykinin receptor antagonist WIN 64338.

J. Salvino, R. Dolle, D. Sawutz, 1995, Canadian journal of physiology and pharmacology.

Synthesis, characterization, and conformational analysis of the D/L-Tic7 stereoisomers of the bradykinin receptor antagonist D-Arg0[Hyp3,Thi5,D-Tic7,Oic8]bradykinin.

J. Salvino, R. Dolle, B. Douty, 1994, Biochemistry.

Structure activity relationships of non-peptide bradykinin B2 receptor antagonists

J. Salvino, R. Dolle, D. Hoyer, 1995 .

Ace inhibitors as a template for the design of bradykinin B2 receptor antagonists

R. Dolle, D. Sawutz, W. T. Houck, 1995 .

5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase.

R. Dolle, M. Bobko, D. Sawutz, 1994, Journal of medicinal chemistry.

Novel sulfamoyl benzamides as selective CB(2) agonists with improved in vitro metabolic stability.

Michael Koblish, R. Dolle, L. Leister, 2010, Bioorganic & medicinal chemistry letters.

Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists.

Michael Koblish, R. Dolle, Christopher T Saeui, 2009, Bioorganic & medicinal chemistry letters.

CB2 selective sulfamoyl benzamides: optimization of the amide functionality.

Michael Koblish, R. Dolle, Markku A. Savolainen, 2009, Bioorganic & medicinal chemistry letters.

Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands.

Michael Koblish, R. Dolle, Christopher T Saeui, 2008, Bioorganic & medicinal chemistry letters.

Biaryl cannabinoid mimetics--synthesis and structure-activity relationship.

R. Dolle, R. Dehaven, Karin Worm, 2007, Bioorganic & medicinal chemistry letters.

Design of potent non-peptide competitive antagonists of the human bradykinin B2 receptor.

J. Salvino, R. Dolle, B. Douty, 1993, Journal of medicinal chemistry.

Studies on the acid-catalyzed homonuclear steroidal diene isomerization

R. Dolle, D. Eggleston, L. Kruse, 1988 .

Improved preparation of (3.beta.,5.alpha.,14.alpha.)-3-hydroxy-14-methylcholest-7-en-15-one. Synthesis of ergostenone and 20.alpha.-(hydroxymethyl)pregnenone analogs

R. Dolle, L. Kruse, 1986 .

Comprehensive survey of combinatorial library synthesis: 2000.

R. Dolle, 2001, Journal of combinatorial chemistry.

Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.

R. Dolle, Qingyi Yang, T. Moy, 2015, ACS medicinal chemistry letters.

Palladium catalysed alkoxycarbonylation of phenols to benzoate esters

R. Dolle, L. Kruse, S. Schmidt, 1987 .

Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.

R. Cheng, C. Scheich, M. Mesleh, 2016, Bioorganic & medicinal chemistry letters.

CD45 protein tyrosine phosphatase: Determination of minimal peptide length for substrate recognition and synthesis of some tyrosine-based electrophiles as potential active-site directed irreversible inhibitors

A. Saha, R. Dolle, M. Bobko, 1995 .

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.

Roland E. Dolle, R. Dolle, Craig J. Thomas, 2010, Journal of combinatorial chemistry.

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2008.

Wei Zhang, Guillermo A Morales, Roland E Dolle, 2009, Journal of combinatorial chemistry.

Additions and Corrections - Total Synthesis of Elfamycins: Aurodox and Efrotomycin. 1. Strategy and Construction of Key Intermediates

K. Nicolaou, R. Dolle, 1985 .

Further studies of tyrosine surrogates in opioid receptor peptide ligands.

T. Graczyk, R. Dolle, R. Dehaven, 2007, Bioorganic & medicinal chemistry letters.

Enantioselective synthesis of (+)-pinidine

R. Dolle, Chunju Li, K. I. Osifo, 1991 .

Allylindium and allylboronic acid pinacolate: Mild reagents for the allylation of resin-bound aldehydes. Application to the solid-phase synthesis of hydroxypropylamines

C. Cavallaro, R. Dolle, T. Herpin, 1999 .

The copper sites of dopamine beta-hydroxylase: an X-ray absorption spectroscopic study.

R. A. Scott, R. Dolle, L I Kruse, 1988, Biochemistry.

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2007.

Wei Zhang, Guillermo A Morales, Roland E Dolle, 2008, Journal of combinatorial chemistry.

Comprehensive survey of combinatorial libraries with undisclosed biological activity: 1992–1997

Roland E. Dolle, R. Dolle, 2004, Molecular Diversity.

Comprehensive survey of combinatorial library synthesis: 2002.

Roland E Dolle, R. Dolle, 2003, Journal of combinatorial chemistry.

Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-3-hydroxy-4-(spiro[chromene-2,4'-piperidine]-4-yl) benzamide (ADL5747).

T. Graczyk, Michael Koblish, R. Dolle, 2009, Journal of medicinal chemistry.

Annulation of Primary Amines to Piperazines and Diazaspirocycles Utilizing α-Methyl Benzyl Resin

C. Macleod, R. Dolle, B. Martínez-Teipel, 2006 .

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2006.

Wei Zhang, J. Salvino, R. Dolle, 2007, Journal of combinatorial chemistry.

Reactions of glycosyl fluorides. Synthesis of C-glycosides

K. Nicolaou, R. Dolle, J. Randall, 1984 .

Comprehensive survey of combinatorial library synthesis: 2003.

Roland E Dolle, R. Dolle, 2004, Journal of combinatorial chemistry.

Application of the intramolecular azomethine imine cycloaddition to the construction of a novel, orthogonally protected spirodiamino acid scaffold

P. Brennan, R. Dolle, D. Ho, 1999 .

Mechanism and inhibition of delta 24-sterol methyltransferase from Candida albicans and Candida tropicalis.

J. Adams, R. Dolle, M. Ator, 1989, Biochemistry.

Total synthesis of ionophore antibiotic X-14547A

K. Nicolaou, R. Magolda, R. Dolle, 1985 .

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2007.

Roland E. Dolle, Wei Zhang, Wei Zhang, 2008, Journal of combinatorial chemistry.

Solid‐Phase Synthesis of Heterocyclic Systems (Heterocycles Containing One Heteroatom)

R. Dolle, 2005 .

Total synthesis of ionophore antibiotic X-14547A

K. Nicolaou, R. Magolda, R. Dolle, 1985 .

Design and synthesis of 14 alpha-methyl-15-aza-D-homosterols as novel antimycotics.

R. Dolle, L. Kruse, H. S. Allaudeen, 1990, Journal of medicinal chemistry.

Enantioselective Synthesis of (+)-Pinidine (I).

R. Dolle, Chunju Li, K. I. Osifo, 1992 .

Novel malonamide derivatives as potent κ opioid receptor agonists

T. Graczyk, Michael Koblish, R. Dolle, 2007 .

Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library.

I. Gluzman, D. Goldberg, M. Orlowski, 1998, Bioorganic & medicinal chemistry letters.

Intramolecular [4+2] cycloaddition of α,β-unsaturated hydrazones as a route to annelated pyridines

A. Shaw, R. Dolle, R. Novelli, 1988 .

Azepinone as a conformational constraint in the design of κ-opioid receptor agonists

Michael Koblish, R. Dolle, J. Cassel, 2004 .

Synthesis and evaluation of (+) and (-)-2,2-difluorocitrate as inhibitors of rat-liver ATP-citrate lyase and porcine-heart aconitase.

D G Reid, P. Camilleri, R. Dolle, 1991, European journal of biochemistry.

Total synthesis of elfamycins: aurodox and efrotomycin. 2. Coupling of key intermediates and completion of the synthesis

K. Nicolaou, R. Dolle, 1985 .

Synthesis of zymosterol, fecosterol, and related biosynthetic sterol intermediates

K. Erhard, R. Dolle, L. Kruse, 1989 .

First Examples of Peptidomimetic Inhibitors of Interleukin-1β Converting Enzyme

A. Saha, C. Prouty, J. Salvino, 1996 .

Synthesis and evaluation of azapeptide-derived inhibitors of serine and cysteine proteases☆

M. Ross, T. Graybill, R. Dolle, 1992 .

Inactivation of dopamine beta-hydroxylase by p-cresol: isolation and characterization of covalently modified active site peptides.

C. Southan, S. Carr, R. Dolle, 1988, Biochemistry.

Comprehensive survey of combinatorial library synthesis: 1999.

R. Dolle, R E Dolle, 2000, Journal of combinatorial chemistry.

Comprehensive survey of chemical libraries yielding enzyme inhibitors, receptor agonists and antagonists, and other biologically active agents: 1992 through 1997

Roland E. Dolle, R. Dolle, 2004, Molecular Diversity.

Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase.

J. Adams, R. Dolle, M. Ator, 1992, Journal of medicinal chemistry.

Total synthesis of ionophore antibiotic X-14547A. 1. Enantioselective synthesis of the tetrahydropyran and tetrahydroindan building blocks

K. Nicolaou, R. Dolle, D. Claremon, 1981 .

Synthesis of novel thiol-containing citric acid analogues. Kinetic evaluation of these and other potential active-site-directed and mechanism-based inhibitors of ATP citrate lyase.

P. Groot, R. Dolle, T. Wells, 1995, Journal of medicinal chemistry.

A GENERAL AND STEREOCONTROLLED TOTAL SYNTHESIS OF LEUKOTRIENE B4 AND ANALOGS

B. D. Harris, K. Nicolaou, R. Dolle, 1984 .

9-(Sulfoximinoalkyl)guanine nucleosides as potential antiherpetic agents

R. Dolle, D. McNair, 1993 .

10-hydroxy-10,9-boroxarophenanthrenes: versatile synthetic intermediates to 3,4-benzocoumarins and triaryls.

R. Dolle, Karin Worm, Q. J. Zhou, 2004, The Journal of organic chemistry.

Carbohydrate-based syntheses of the goldinonolactone and the tetrahydrofuran fragments of aurodox and efrotomycin

K. Nicolaou, R. Dolle, 1985 .

Experiences in Academic and Industry Partnerships – Forging a Path to Translational Drug Discovery

Vadim J. Gurvich, N. Carragher, S. Frye, 2021 .

Design and Synthesis of Imidazopyrimidine Derivatives as Potent iNOS Dimerization Inhibitors

R. Dolle, L. Leister, J. Cassel, 2009, The open medicinal chemistry journal.

Novel phenylamino acetamide derivatives as potent and selective κ opioid receptor agonists

Michael Koblish, R. Dolle, J. Cassel, 2006 .

Novel phenylamino acetamide derivatives as potent and selective kappa opioid receptor agonists.

Michael Koblish, R. Dolle, J. Cassel, 2006, Bioorganic & medicinal chemistry letters.

Mu Opioid Receptor Antagonists: Recent Developments

R. Dolle, Allan J. Goodman, Bertrand Le Bourdonnec, 2007, ChemMedChem.

δ-Opioid Mechanisms for ADL5747 and ADL5859 Effects in Mice: Analgesia, Locomotion, and Receptor Internalization

Roland E Dolle, C. Gaveriaux-Ruff, B. Kieffer, 2012, Journal of Pharmacology and Experimental Therapeutics.

Reducing Auditory Nerve Excitability by Acute Antagonism of Ca2+-Permeable AMPA Receptors

A. Salt, S. Goodman, Choongheon Lee, 2021, Frontiers in Synaptic Neuroscience.

The development and application of tetrafluorophenol-activated resins for rapid amine derivatization.

J. Salvino, R. Dolle, 2003, Methods in enzymology.

Microwave-assisted Synthesis of Di- and trisubstituted Ureas from Thiophenoxy Carbamate Resins

R. Dolle, B. Martínez-Teipel, R. Green, 2004 .

Combined solution-phase and solid-phase synthesis of 2-amino-7,8-dihydropteridin-6(5H)-ones

H. Gstach, J. Baldwin, A. Metzger, 2009 .

Synthesis of (±)-3-amino-2-(4-chlorophenyl)propanesulfonic acid (Saclofen)

R. Dolle, W. Howson, Chun-Sing Li, 1991 .

Peripherally restricted opioid agonists as novel analgesic agents.

R. Dolle, R E Dolle, D. DeHaven-Hudkins, 2004, Current pharmaceutical design.

Inhibition of Human Erythrocyte Calpain I by Novel Quinolinecarboxamides.

T. Graybill, R. Dolle, Matthew S. Miller, 1995 .

Characterization of a continuous fluorogenic assay for calpain I. Kinetic evaluation of peptide aldehydes, halomethyl ketones and (acyloxy)methyl ketones as inhibitors of the enzyme

T. Graybill, R. Dolle, A. Maycock, 1995 .

Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design.

M. Mesleh, J. Barker, R. Dolle, 2016, ACS medicinal chemistry letters.

Development of Polyperfluoroalkylethers as High Temperature Lubricants and Hydraulic Fluids

R. Dolle, C. Snyder, 1976 .

ATP-Citrate lyase as a target for hypolipidemic intervention. 2. Synthesis and evaluation of (3R,5S)-omega-substituted-3-carboxy-3, 5-dihydroxyalkanoic acids and their gamma-lactone prodrugs as inhibitors of the enzyme in vitro and in vivo.

D. Tew, H. Boyd, A. Shaw, 1998, Journal of medicinal chemistry.

ATP-citrate lyase as a target for hypolipidemic intervention. Design and synthesis of 2-substituted butanedioic acids as novel, potent inhibitors of the enzyme.

D. Tew, A. Shaw, P. Groot, 1996, Journal of medicinal chemistry.

Discovery of 6-Phenylhexanamide Derivatives as Potent Stereoselective Mitofusin Activators for the Treatment of Mitochondrial Diseases.

G. Dorn, P. Bernstein, Lihong Zhang, 2020, Journal of medicinal chemistry.

The nonpeptide WIN 64338 is a bradykinin B2 receptor antagonist.

J. Salvino, R. Dolle, B. Douty, 1994, Proceedings of the National Academy of Sciences of the United States of America.

(4-Carboxamido)phenylalanine is a surrogate for tyrosine in opioid receptor peptide ligands.

T. Graczyk, R. Dolle, J. Cassel, 2004, Bioorganic & medicinal chemistry letters.

Potent, orally bioavailable delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide (ADL5859).

T. Graczyk, Michael Koblish, R. Dolle, 2008, Journal of medicinal chemistry.

Sphingolipid Biosynthesis Inhibition As A Host Strategy Against Diverse Pathogens

J. Carette, T. Brummelkamp, A. Pendergrass, 2020, bioRxiv.

Simultaneous optimization of potency, selectivity and physicochemical properties for cannabinoid CB(2) ligands.

R. Dolle, Karin Worm, 2009, Current pharmaceutical design.

Preparation of (±)-(erythro)-and (±)-(threo)-2-vinyl citric acids as potential mechanism-based inhibitors of ATP-citrate lyase

P. Camilleri, R. Dolle, T. Wells, 1991 .

Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles.

R. Dolle, J. Cassel, B. Le Bourdonnec, 2008, Bioorganic & medicinal chemistry letters.

Design and Synthesis of 14α-Methyl-15-aza-D-homosterols as Novel Antimycotics.

R. Dolle, L. Kruse, H. S. Allaudeen, 1990 .

Antinociceptive activity of the selective iNOS inhibitor AR‐C102222 in rodent models of inflammatory, neuropathic and post‐operative pain

Michael Koblish, R. Dolle, P. Tuthill, 2006, European journal of pain.

Delta opioid mechanisms for ADL 5747 and ADL 5859 effects in mice : analgesia , locomotion and receptor internalization

C. Gaveriaux-Ruff, B. Kieffer, R. Dolle, 2012 .

Nascent structure-activity relationship study of a diastereomeric series of kappa opioid receptor antagonists derived from CJ-15,208.

P. Carroll, R. Dolle, R. Dehaven, 2009, Bioorganic & medicinal chemistry letters.

1 – High Throughput Analysis of Combinatorial Libraries Encoded with Electrophoric Molecular Tags

Ian Henderson, Joan Guo, Lawrence W. Dillard, 2004 .

Deconvolution methods in solid-phase synthesis

J. Baldwin, R. Dolle, 1997 .

Evaluation of a structure-based statine cyclic diamino amide encoded combinatorial library against plasmepsin II and cathepsin D.

I. Gluzman, D. Goldberg, M. Orlowski, 1998, Bioorganic & medicinal chemistry letters.

Design and synthesis of a series of glycerol-derived receptor mediated calcium entry (RMCE) blockers

T. Rink, K. Cassidy, R. Dolle, 1990 .

Confronting the COVID ‐19 Pandemic: December 2019–May 2020

M. Kinch, R. Dolle, D. J. Abraham, 2021 .

Synthesis and structure-activity relationships of a new series of 2alpha-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as mu-selective opioid antagonists.

T. Graczyk, R. Dolle, B. Le Bourdonnec, 2006, Bioorganic & medicinal chemistry letters.

trans-3,4-dimethyl-4-(3-carboxamidophenyl)piperidines: a novel class of micro-selective opioid antagonists.

R. Dolle, J. Cassel, B. Le Bourdonnec, 2003, Bioorganic & medicinal chemistry letters.

Historical overview of chemical library design.

Roland E Dolle, R. Dolle, 2011, Methods in molecular biology.

Synthesis of (±)-3-Amino-2-(4-chlorophenyl)propanesulfonic acid (Saclofen)

R. Dolle, W. Howson, C. Li, 1991 .

Conformational analysis of bradykinin by annealed molecular dynamics and comparison to NMR‐derived conformations

Roland E. Dolle, Joseph M. Salvino, Peter R. Seoane, 1993, J. Comput. Chem..

Elucidation of the bioactive conformation of the N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine class of mu-opioid receptor antagonists.

T. Graczyk, T. Herbertz, R. Dolle, 2006, Journal of medicinal chemistry.

Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands.

Michael Koblish, R. Dolle, Christopher T Saeui, 2008, Bioorganic & medicinal chemistry letters.

Biaryl cannabinoid mimetics--synthesis and structure-activity relationship.

R. Dolle, R. Dehaven, Karin Worm, 2007, Bioorganic & medicinal chemistry letters.

The Discovery and Development of the N‐Substituted trans‐3,4‐Dimethyl‐4‐(3′‐hydroxyphenyl)piperidine Class of Pure Opioid Receptor Antagonists

F. Carroll, R. Dolle, 2014, ChemMedChem.

Potent and highly selective kappa opioid receptor agonists incorporating chroman- and 2,3-dihydrobenzofuran-based constraints.

T. Graczyk, Michael Koblish, R. Dolle, 2005, Bioorganic & medicinal chemistry letters.