K. Bowman

发表

A statistical-based approach to assessing the fidelity of combinatorial libraries encoded with electrophoric molecular tags. Development and application of tag decode-assisted single bead LC/MS analysis.

W. Egan, J. Reader, M. Orlowski, 2000, Journal of combinatorial chemistry.

DNA damage of macrophages at an air-tissue interface induced by metal nanoparticles

Jennifer A. Higgins, S. Rhead, J. Grigg, 2009 .

Carbonic anhydrase IX expression and outcome after radiotherapy for muscle-invasive bladder cancer.

K. O'Byrne, J. Mellon, R. Kockelbergh, 2007, Clinical oncology (Royal College of Radiologists (Great Britain)).

Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro

N. Curtin, D. Newell, A. Calvert, 2001, British Journal of Cancer.

Measurements using the alkaline comet assay predict bladder cancer cell radiosensitivity

J. Mellon, R. Kockelbergh, W. Steward, 2003, British Journal of Cancer.

Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells

S. Cowley, J. Schwabe, K. Bowman, 2022, Journal of medicinal chemistry.

DNA strand breaks and hypoxia response inhibition mediate the radiosensitisation effect of nitric oxide donors on prostate cancer under varying oxygen conditions.

J. Ross, F. Habib, D. McLaren, 2011, Biochemical pharmacology.

Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP).

N. Curtin, L. Pemberton, R. Griffin, 1998, Journal of medicinal chemistry.

Evaluation of phosphodiesterase I-based protocols for the detection of multiply damaged sites in DNA: the detection of abasic, oxidative and alkylative tandem damage in DNA oligonucleotides.

P. Farmer, K. Bowman, Y. Guichard, 2001, Nucleic acids research.

Comet assay measures of DNA damage are predictive of bladder cancer cell treatment sensitivity in vitro and outcome in vivo

S. McKeown, V. McKelvey-Martin, J. Mellon, 2014, International journal of cancer.

Fractionated radiation exposure amplifies the radioresistant nature of prostate cancer cells

N. Lynam‐Lennon, B. Marples, K. Bowman, 2016, Scientific Reports.

Novel potent inhibitors of the DNA repair enzyme poly(ADP-ribose)polymerase (PARP).

N. Curtin, J. K. Porteous, L. Pemberton, 1995, Anti-cancer drug design.

Potentiation of anti-cancer agent cytotoxicity by the potent poly(ADP-ribose) polymerase inhibitors NU1025 and NU1064.

N. Curtin, R. Griffin, B. Golding, 1998, British Journal of Cancer.

Novel Benzimidazole and Quinazolinone Inhibitors of the DNA Repair Enzyme Poly(ADP‐ribose)polymerase*

N. Curtin, R. Griffin, B. Golding, 1996 .

DNA damage in earthworms from highly contaminated soils: assessing resistance to arsenic toxicity by use of the Comet assay.

M. Button, K. Bowman, M. Watts, 2010, Mutation research.

Introducing a true internal standard for the Comet assay to minimize intra- and inter-experiment variability in measures of DNA damage and repair

Alexander Rapp, Gabriela M. Almeida, A. Rapp, 2009, Nucleic acids research.

Resistance-modifying agents. 11.(1) Pyrimido[5,4-d]pyrimidine modulators of antitumor drug activity. Synthesis and structure-activity relationships for nucleoside transport inhibition and binding to alpha1-acid glycoprotein.

N. Curtin, Peter G. Smith, R. Griffin, 2004, Journal of medicinal chemistry.

Further development of 32P-postlabeling for the detection of alkylphosphotriesters: evidence for the long-term nonrandom persistence of ethyl-phosphotriester adducts in vivo.

P. Farmer, K. Bowman, M. Gaskell, 2004, Chemical research in toxicology.

Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion

J. Lowe, D. Hussein, R. Grundy, 2010, Neuro-oncology.

SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer

Marina Kriajevska, Thomas R. Griffiths, Andrew Ruddick, 2009, Proceedings of the National Academy of Sciences.

Protection of Cells in Physiological Oxygen Tensions against DNA Damage-induced Apoptosis*

Sam W. Lee, S. Aaronson, S. Macip, 2010, The Journal of Biological Chemistry.

Comet assay measures of DNA damage as biomarkers of irinotecan response in colorectal cancer in vitro and in vivo

K. Bowman, Andrew J. Smith, George D.D. Jones, 2015, Cancer medicine.

Simplified method for the collection, storage, and comet assay analysis of DNA damage in whole blood.

Mahsa Karbaschi, Marcus S Cooke, Mark D Evans, 2011, Free radical biology & medicine.

Improving and predicting radiosensitivity in muscle invasive bladder cancer.

J. Mellon, R. Kockelbergh, A. Colquhoun, 2003, The Journal of urology.

Phosphate alkylation in different DNA substrates: the role of local DNA sequence and electrophile character in determining the nonrandom nature of phosphotriester adduct formation.

P. Farmer, K. Bowman, George D.D. Jones, 2006, Chemical research in toxicology.

Potentiation of the cytotoxicity of thymidylate synthase (TS) inhibitors by dipyridamole analogues with reduced α1-acid glycoprotein binding

N. Curtin, R. Griffin, B. Golding, 1999, British Journal of Cancer.

DNA damage in earthworms from highly contaminated soils: assessing resistance to arsenic toxicity by use of the Comet assay.

M. Button, K. Bowman, M. Watts, 2010, Mutation research.