K. Lind

发表

Design, synthesis and selection of DNA-encoded small-molecule libraries.

Baoguang Zhao, Cecil E. Rise, M. Gefter, 2009, Nature chemical biology.

Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists.

Zhengrong Zhu, M. Shimaoka, T. Springer, 2014, Bioorganic & medicinal chemistry.

Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.

Daniel A Erlanson, D. M. Penny, Lihong Sun, 2011, Bioorganic & medicinal chemistry letters.

Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).

Hongfeng Deng, G Joseph Franklin, Kenneth E Lind, 2012, Journal of medicinal chemistry.

Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening.

Zhihua Du, Kenneth E Lind, Z. Du, 2002, Chemistry & biology.

Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA.

Zhihua Du, Kenneth E Lind, B. Peterlin, 2002, Chemistry & biology.

Erratum: Design, synthesis and selection of DNA-encoded small-molecule libraries

Baoguang Zhao, Cecil E. Rise, M. Gefter, 2009 .

DNA-Encoded Macrocyclic Peptide Library.

Zhengrong Zhu, A. Shaginian, C. Davie, 2019, Methods in molecular biology.

Development of a Selection Method for Discovering Irreversible (Covalent) Binders from a DNA-Encoded Library

Zhengrong Zhu, C. Davie, Yun Ding, 2018, SLAS discovery : advancing life sciences R & D.

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

David M. Wilson, G. Drewes, D. Eberhard, 2015, Nature chemical biology.

Structural characteristics of 2'-O-(2-methoxyethyl)-modified nucleic acids from molecular dynamics simulations.

M. Manoharan, D. Ferguson, V. Mohan, 1998, Nucleic acids research.

The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding.

J. Irving, Zhengrong Zhu, D. Lomas, 2021, Bioorganic & medicinal chemistry letters.

Dihydropteridine reductase. A method for the measurement of activity, and investigations of the specificity for NADH and NADPH.

K. Lind, K. H. Nielsen, V. Simonsen, 1969, European journal of biochemistry.

Enzymatically active Ca2+ ATPase from sarcoplasmic reticulum membranes, solubilized by nonionic detergents. Role of lipid for aggregation of the protein.

J. Møller, M. Maire, K. Lind, 1978, The Journal of biological chemistry.

Effect of some psychotropic drugs and a barbiturate on mycoplasmas.

K. Lind, J. Kristiansen, 2000, International journal of antimicrobial agents.

Structural properties of DNA:RNA duplexes containing 2'-O-methyl and 2'-S-methyl substitutions: a molecular dynamics investigation.

M. Manoharan, D. Ferguson, K. Lind, 1999, Nucleic acids research.

Fragment-based discovery of nonpeptidic BACE-1 inhibitors using tethering.

Jian Sun, D. M. Penny, Wanli Lu, 2009, Biochemistry.

Pyridinonyl-pdk1-hemmer

K. Guckian, N. Pathan, D. Erlanson, 2007 .

Dihydropteridine reductase. Investigation of the specificity for quinoid dihydropteridine and the inhibition by 2,4-diaminopteridines.

K. Lind, 1972, European journal of biochemistry.

Protein binding of small molecules. V. Binding of bromphenol blue by chemical modifications of human serum albumin.

J. Møller, K. Lind, U. Kragh-Hansen, 1974, Biochimica et biophysica acta.

Dihydropteridine reductase. Measurement of dissociation constants for binary complexes of enzyme and ligands.

K. Lind, 1973, European Journal of Biochemistry.

Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT)

J. Cuozzo, M. Clark, Paolo A. Centrella, 2015, ACS medicinal chemistry letters.

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

Gang Yao, Bing Xia, Jing Chai, 2017, Nature Communications.

Enzyme kinetics and substrate stabilization of detergent-solubilized and membraneous (Ca2+ + Mg2+)-activated ATPase from sarcoplasmic reticulum. Effect of protein-protein interactions.

J. Møller, K. Lind, J. Andersen, 1980, The Journal of biological chemistry.

Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3.

Siva Lavu, Lei Jin, T. Graybill, 2013, Journal of medicinal chemistry.

Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2.

C. D. Thompson, G. Hannig, C. Arico-Muendel, 2009, Journal of medicinal chemistry.

Encoded Library Technology Screening of Hepatitis C Virus NS4B Yields a Small-Molecule Compound Series with In Vitro Replicon Activity

Zhengrong Zhu, T. Graybill, M. Thomson, 2015, Antimicrobial Agents and Chemotherapy.

Parameterization and Simulation of the Physical Properties of Phosphorothioate Nucleic Acids

R. Griffey, D. Ferguson, V. Mohan, 1998 .

Protein binding of small molecules: IV. Relation between binding of phenolsulfophthalein dyes and other ligands with a high affinity for human serum albumin

J. Møller, K. Lind, U. Kragh-Hansen, 1974 .

Development of a small molecule that corrects misfolding and increases secretion of Z α1-antitrypsin

J. Irving, Zhengrong Zhu, D. Lomas, 2020, bioRxiv.

Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).

J. Cuozzo, M. Clark, Raksha A. Acharya, 2012, Journal of medicinal chemistry.

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

Robert H Bates, G. Besra, J. Lelièvre, 2017, Nature Communications.