B. Morgan

发表

Design, synthesis and selection of DNA-encoded small-molecule libraries.

Baoguang Zhao, Cecil E. Rise, M. Gefter, 2009, Nature chemical biology.

Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists.

Zhengrong Zhu, M. Shimaoka, T. Springer, 2014, Bioorganic & medicinal chemistry.

Somatostatin receptor subtype specificity in human fetal pituitary cultures. Differential role of SSTR2 and SSTR5 for growth hormone, thyroid-stimulating hormone, and prolactin regulation.

S. Melmed, I. Shimon, J. Taylor, 1997, The Journal of clinical investigation.

Identification of two related pentapeptides from the brain with potent opiate agonist activity

H. Morris, L. Fothergill, B. Morgan, 1975, Nature.

Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).

Hongfeng Deng, G Joseph Franklin, Kenneth E Lind, 2012, Journal of medicinal chemistry.

Side reactions and cadmium catalysed removal of the trichloro-ethoxycarbonyl (troc) protecting group.

B. Morgan, G. Hancock, I. Galpin, 1982 .

Erratum: Design, synthesis and selection of DNA-encoded small-molecule libraries

Baoguang Zhao, Cecil E. Rise, M. Gefter, 2009 .

In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor.

R. Mayer, D. Behm, S. Sweitzer, 2013, Prostaglandins & other lipid mediators.

Antiparasitic activities of novel, orally available fumagillin analogs.

Anjan Debnath, Joseph L DeRisi, Jiri Gut, 2009, Bioorganic & medicinal chemistry letters.

Chapter 4 Analgetics, Endorphins and the Opioid Receptor

B. Morgan, R. Kobylecki, 1979 .

Pseudopeptide farnesyl-protein transferase inhibitors containing 5,5-dimethylthiazolidine-4-carboxylic acid

B. Morgan, P. Kasprzyk, G. Prévost, 2002 .

Structure‐activity relationships of methionine‐enkephalin

B. Morgan, J. Hughes, H. Kosterlitz, 1976, The Journal of pharmacy and pharmacology.

Analogues of β-LPH61–64 posessing selective agonist activity at μ-opiate receptors

B. Morgan, COLIN F. C. Smith, B. Handa, 1981 .

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library.

C. Chung, A. Satz, M. Clark, 2015, ACS medicinal chemistry letters.

Immobilized peptide arrays: A new technology for the characterization of protease function

B. Morgan, D. Whipple, T. Siahaan, 1994 .

Peptide azoles: A new class of biologically-active dipeptide mmetics.

B. Morgan, Jasbir Singh, T. Gordon, 1993 .

Chemical synthesis and receptor binding of catfish somatostatin: a disulfide‐bridged β‐d‐Galp‐(1→3)‐α‐d‐GalpNAc O‐glycopeptide*

B. Morgan, John E. Taylor, G. Bárány, 2000 .

Orally active fumagillin analogues: transformations of a reactive warhead in the gastric environment.

C. D. Thompson, Amy A Sarjeant, C. Arico-Muendel, 2013, ACS medicinal chemistry letters.

Chapter 19. Biochemistry and Inhibition of Collagenase and Stromelysin

R. Wahl, B. Morgan, R. P. Dunlap, 1990 .

Exploring amino acids derivatives as potent, selective, and direct agonists of sphingosine-1-phosphate receptor subtype-1.

B. Morgan, G. Evindar, H. Deng, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists.

A. Saha, G. Hannig, M. Kavarana, 2009, Bioorganic & medicinal chemistry letters.

Synthesis of substituted imidazopyrazines as ligands for the human somatostatin receptor subtype 5.

B. Morgan, T. Gordon, C. Thurieau, 2001, Bioorganic & medicinal chemistry letters.

Potent antagonists of somatostatin: synthesis and biology.

J. Taylor, D. Coy, S. Hocart, 1998, Journal of medicinal chemistry.

Novel non-peptide ligands for the somatostatin sst3 receptor.

B. Morgan, T. Gordon, M. Contour-Galcéra, 2001, Bioorganic & medicinal chemistry letters.

Pharmacology identification of two related pentapeptides from the brain with potent opiate agonist activity Nature (Lond.), 258 (1975) 577–579

H. Morris, L. Fothergill, B. Morgan, 1976, Pain.

Synthesis and binding potencies of cyclohexapeptide somatostatin analogs containing naphthylalanine and arylalkyl peptoid residues

J. Taylor, B. Morgan, John E. Taylor, 1999, Journal of peptide science : an official publication of the European Peptide Society.

Chapter 4. Analgesics, Endorphins, and the Opiate Receptor

B. Morgan, R. Kobylecki, 1980 .

Modification of the proline residue of TRH enhances biological activity and inhibits degradation.

G. Metcalf, B. Morgan, P. Dettmar, 1980, European journal of pharmacology.

Chapter 26. Approaches to the Discovery of Non-Peptide Ligands for Peptide Receptors and Peptidases

B. Morgan, J. Gainor, 1989 .

An efficient synthesis and acylation of α-amino-β-keto-esters: Versatile intermediates in the synthesis of peptide mimetics.

B. Morgan, Jasbir Singh, T. Gordon, 1993 .

Mode of deactivation of the enkephalins by rat and human plasma and rat brain homogenates

B. Morgan, COLIN F. C. Smith, M. J. Rance, 1976, Nature.

The synthesis of an insulin active site analogue

B. Morgan, G. Hancock, I. Galpin, 1983 .

Synthetic approaches to the ‘Azole’ peptide mimetics

B. Morgan, Jasbir Singh, T. Gordon, 1993 .

A novel approach to the synthesis of thiazole amino acids

B. Morgan, T. Gordon, 1992 .

Enkephalin. Synthesis of two pentapeptides isolated from porcine brain with receptor-mediated opiate agonist activity.

B. Morgan, J. Bower, K. P. Guest, 1976, Journal of the Chemical Society. Perkin transactions 1.

Rapid, continuous solution-phase peptide synthesis: Application to peptides of pharmaceutical interest

B. Morgan, M. Ismail, L. A. Carpino, 2003 .

Metabolites of PPI-2458, a Selective, Irreversible Inhibitor of Methionine Aminopeptidase-2: Structure Determination and In Vivo Activity

C. D. Thompson, C. Arico-Muendel, D. Benjamin, 2013, Drug Metabolism and Disposition.

DMD048355 814..826

C. D. Thompson, C. Arico-Muendel, D. Benjamin, 2013 .

Purification and properties of enkephalin - the possible endogenous ligand for the morphine receptor.

L. Fothergill, B. Morgan, T. Smith, 1975, Life sciences.

Tetracycline studies. Part IV. Some novel cyclisations through benzophenone carbanions, including a new synthesis of anthraquinones

B. Morgan, C. Hassall, 1973 .

Discovery of Clinical Candidate GSK1842799 As a Selective S1P1 Receptor Agonist (Prodrug) for Multiple Sclerosis.

B. Morgan, G. Evindar, H. Deng, 2013, ACS medicinal chemistry letters.

Analogues of beta-LPH61-64 possessing selective agonist activity at mu-opiate receptors.

B. Morgan, C. Smith, B. Handa, 1981, European journal of pharmacology.

Effect of synthetic thyrotrophin-releasing hormone and its analogues on growth hormone secretion in the domestic fowl (Gallus domesticus).

C. Scanes, B. Morgan, S. Harvey, 1981, Acta endocrinologica.

Structure – Activity Relationships in Enkephalin Peptides

B. Morgan, P. Hansen, 1984 .

Determination of the chirality of cysteines in somatostatin analogs

B. Morgan, T. Sambandan, P. Jacobson, 1998 .

Synthesis and binding potencies of cyclic hexapeptide analogs of somatostatin incorporating acidic and basic peptoid residues.

J. Taylor, B. Morgan, M. Goodman, 1999, The journal of peptide research : official journal of the American Peptide Society.

Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.

W. K. Sonnenburg, P. Kung, Sergei L Timofeevski, 2020, ACS medicinal chemistry letters.

Relationship between structure and bioavailability in a series of hydroxamate based metalloprotease inhibitors

R. Wahl, B. Morgan, D. Whipple, 1995 .

Improved analogs and novel delivery systems for somatostatin octapeptides.

J. Taylor, F. Ignatious, B. Morgan, 1996, Metabolism: clinical and experimental.

Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists.

A. Saha, G. Hannig, A. Satz, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists.

A. Saha, G. Hannig, A. Satz, 2009, Bioorganic & medicinal chemistry letters.

PAC-FragmentDEL – photoactivated covalent capture of DNA-encoded fragments for hit discovery

W. Finnie, J. Murray, R. Hubbard, 2022, RSC medicinal chemistry.

STRUCTURE-FUNCTION STUDIES IN PEPTIDES RELATED TO THE β-LPH61-64 SEQUENCE

G. Metcalfe, B. Morgan, J. Bower, 1980 .

Rapid Determination of Substrate Specificity of Clostridium histolyticum β-Collagenase Using an Immobilized Peptide Library*

B. Morgan, Yongbo Hu, T. Siahaan, 2002, The Journal of Biological Chemistry.

Syntheses and biological activities of sandostatin analogs containing stereochemical changes in positions 6 or 8.

D. Hoyer, J. Taylor, B. Morgan, 2000, Biopolymers.

Crystal structure of [Leu5]enkephalin.

T. Blundell, G. D. Smith, B. Morgan, 1979, Science.

Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT).

Yun Ding, J. Cuozzo, D. Israel, 2015, ACS medicinal chemistry letters.

Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2.

C. D. Thompson, G. Hannig, C. Arico-Muendel, 2009, Journal of medicinal chemistry.

Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT).

D. Israel, J. Marino, M. Clark, 2021, Bioorganic & medicinal chemistry.

Employing Photocatalysis for the Design and Preparation of DNA‐Encoded Libraries: A Case Study

B. Morgan, M. Flanagan, Dominik K. Kölmel, 2021, The chemical record.

Validation of screening immobilized peptide libraries for discovery of protease substrates.

A. Treasurywala, B. Morgan, J. Solowiej, 1995, Journal of Medicinal Chemistry.

Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).

J. Cuozzo, M. Clark, Raksha A. Acharya, 2012, Journal of medicinal chemistry.

Biological evaluation of a TRH analogue with a modified proline residue

G. Metcalf, B. Morgan, P. Dettmar, 1980, Neuropharmacology.

Design, synthesis, and biological activities of potent and selective somatostatin analogues incorporating novel peptoid residues.

O. Ziv, D. Hoyer, J. Taylor, 1998, Journal of medicinal chemistry.

Brain TRH receptors are the same as pituitary TRH receptors

G. Metcalf, B. Morgan, P. Dettmar, 1983, The Journal of pharmacy and pharmacology.

Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.

W. K. Sonnenburg, P. Kung, M. Gehring, 2020, ACS medicinal chemistry letters.