O. Nemirovskiy

发表

A Novel Autotaxin Inhibitor Reduces Lysophosphatidic Acid Levels in Plasma and the Site of Inflammation

J. Gierse, J. Masferrer, A. Wittwer, 2010, Journal of Pharmacology and Experimental Therapeutics.

Design and validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide in human urine: application as a biomarker of osteoarthritis.

O. Nemirovskiy, W. Li, Gabriella Szekely‐Klepser, 2010, Methods in molecular biology.

Clinical validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide: A biomarker of matrix metalloproteinase activity and osteoarthritis in human urine.

O. Nemirovskiy, W. Li, Gabriella Szekely‐Klepser, 2007, Analytical biochemistry.

ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271).

D. Griggs, T. Hall, O. Nemirovskiy, 2009, Arthritis and rheumatism.

High-Throughput Screening Assay for Sphingosine Kinase Inhibitors in Whole Blood Using RapidFire® Mass Spectrometry

J. Masferrer, O. Nemirovskiy, W. Lamarr, 2011, Journal of biomolecular screening.

Biochemical, Cellular, and Anti-Inflammatory Properties of a Potent, Selective, Orally Bioavailable Benzamide Inhibitor of Rho Kinase Activity

J. Masferrer, M. B. Norton, M. Payne, 2010, Journal of Pharmacology and Experimental Therapeutics.

Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.

T. Kasten, J. Chrencik, A. Wittwer, 2012, The Biochemical journal.

An immunoaffinity liquid chromatography-tandem mass spectrometry assay for detection of endogenous aggrecan fragments in biological fluids: Use as a biomarker for aggrecanase activity and cartilage degradation.

O. Nemirovskiy, M. Tortorella, A. Malfait, 2010, Analytical biochemistry.

Plasma 3-nitrotyrosine is a biomarker in animal models of arthritis: Pharmacological dissection of iNOS' role in disease.

O. Nemirovskiy, T. Sunyer, T. P. Misko, 2009, Nitric oxide : biology and chemistry.

Cartilage degradation biomarkers predict efficacy of a novel, highly selective matrix metalloproteinase 13 inhibitor in a dog model of osteoarthritis: confirmation by multivariate analysis that modulation of type II collagen and aggrecan degradation peptides parallels pathologic changes.

Dean M. Messing, A. Bendele, O. Nemirovskiy, 2010, Arthritis and rheumatism.

Discovery and development of the N-terminal procollagen type II (NPII) biomarker: a tool for measuring collagen type II synthesis.

M. Hellio le Graverand, O. Nemirovskiy, T. Sunyer, 2008, Osteoarthritis and cartilage.

Complexes of iron(II) with cysteine-containing peptides in the gas phase

M. Gross, O. Nemirovskiy, 1996, Journal of the American Society for Mass Spectrometry.

Unexpected fragmentation of β-substituted meso-tetraphenylporphyrins induced by high-energy collisional activation

M. Gross, M. Neves, J. Cavaleiro, 2002, Journal of the American Society for Mass Spectrometry.

Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor.

J. Gierse, J. Masferrer, J. Carter, 2010, Biochemical pharmacology.

High- and low-energy collisionally activated decompositions of octaethylporphyrin and its metal complexes

M. Graco, M. Gross, M. Neves, 1998, Journal of the American Society for Mass Spectrometry.

Electrospray ionization mass spectrometry and hydrogen/deuterium exchange for probing the interaction of calmodulin with calcium

M. Gross, O. Nemirovskiy, D. Giblin, 1999, Journal of the American Society for Mass Spectrometry.

Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: from in vitro to in vivo.

O. Nemirovskiy, T. Sunyer, D. Dufield, 2007, Analytical biochemistry.

Do charge-remote fragmentations occur under matrix-assisted laser desorption ionization post-source decompositions and matrix-assisted laser desorption ionization collisionally activated decompositions?

M. Gross, M. Neves, J. Cavaleiro, 1999, Journal of the American Society for Mass Spectrometry.

Intrinsic Ca2+ affinities of peptides: Application of the kinetic method to analogs of calcium-binding site III of rabbit skeletal troponin C

O. Nemirovskiy, Michael L. Gross, 2000, Journal of the American Society for Mass Spectrometry.

Investigation of calcium-induced, noncovalent association of calmodulin with melittin by electrospray ionization mass spectrometry

M. Gross, O. Nemirovskiy, R. Ramanathan, 1997 .

Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.

R. D. Dyer, Adam R. Johnson, K. Aston, 2010, Bioorganic & medicinal chemistry letters.

Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry.

Y. Lai, O. Nemirovskiy, Chengjie Ji, 2008, Analytical biochemistry.

Association between concentrations of urinary type II collagen neoepitope (uTIINE) and joint space narrowing in patients with knee osteoarthritis.

R. Buck, K. Brandt, S. Mazzuca, 2006, Osteoarthritis and cartilage.

Differentiation of positional isomers of nitro meso-tetraphenylporphyrins by tandem mass spectrometry

M. Gross, P. Domingues, M. Neves, 2001, Journal of the American Society for Mass Spectrometry.

Recent Advances in Magnet Sector Mass Spectrometry

M. Gross, O. Nemirovskiy, R. Ramanathan, 1997 .

Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development

M. Karsdal, C. Christiansen, E. Dam, 2009, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Pharmacokinetic/pharmacodynamic (PK/PD) differentiation of native and PEGylated recombinant human growth hormone (rhGH and PEG-rhGH) in the rat model of osteoarthritis

O. Nemirovskiy, T. Sunyer, D. Aguiar, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

LC-MS/MS mediated absolute quantification and comparison of bile salt export pump and breast cancer resistance protein in livers and hepatocytes across species.

Na Li, Joe Palandra, Yurong Lai, 2009, Analytical chemistry.

Identification of an ADAMTS-4 Cleavage Motif Using Phage Display Leads to the Development of Fluorogenic Peptide Substrates and Reveals Matrilin-3 as a Novel Substrate*

R. Mazzarella, Min Liu, O. Nemirovskiy, 2007, Journal of Biological Chemistry.

Immunoaffinity liquid chromatography-tandem mass spectrometry detection of nitrotyrosine in biological fluids: development of a clinically translatable biomarker.

O. Nemirovskiy, Melissa R Radabaugh, T. P. Misko, 2008, Analytical biochemistry.

Determination of calcium binding sites in gas-phase small peptides by tandem mass spectrometry

M. Gross, O. Nemirovskiy, Olga V. Nemirovskiy, 1998, Journal of the American Society for Mass Spectrometry.