Xin Zeng

发表

Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor.

Jean Zhang, T. Graybill, D. Israel, 2015, ACS combinatorial science.

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling

Ossama Tawfik, Qiang Tian, Xin Zeng, 2004, Nature Genetics.

Inhibition of Wnt/β‐catenin signaling downregulates P‐glycoprotein and reverses multi‐drug resistance of cholangiocarcinoma

Xin Zeng, Wei Zhang, Dong-Yan Shen, 2013, Cancer science.

Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway

J. Bertin, V. Kasparcova, Jong W. Yu, 2013, PloS one.

Identification of Selective Small Molecule Inhibitors of the Nucleotide-Binding Oligomerization Domain 1 (NOD1) Signaling Pathway

J. Bertin, V. Kasparcova, Zining Wu, 2014, PloS one.

A system for screening agonists targeting β2-adrenoceptor from chinese medicinal herbs

Xin Zeng, Hui Wang, Shi-you Li, 2009, Journal of Zhejiang University SCIENCE B.

High-Throughput Screening and Triage Assays Identify Small Molecules Targeting c-MYC in Cancer Cells

Anthony Della Pietra, J. R. Medina, Xin Zeng, 2021, SLAS discovery : advancing life sciences R & D.

Pirfenidone inhibits carbon tetrachloride‐ and albumin complex‐induced liver fibrosis in rodents by preventing activation of hepatic stellate cells

Bao-en Wang, Xin Zeng, Tai-ling Wang, 2009, Clinical and experimental pharmacology & physiology.

RhoH modulates pre-TCR and TCR signalling by regulating LCK.

B. Lim, Hong Wang, Xin Zeng, 2011, Cellular signalling.

Xi He, Xin Zeng, Mikhail Semenov, 2004, Development.

A freely diffusible form of Sonic hedgehog mediates long-range signalling

Xin Zeng, D. Robbins, W. Scott, 2001, Nature.

Development of Phenotypic Screening Assays for γ-Globin Induction Using Primary Human Bone Marrow Day 7 Erythroid Progenitor Cells

Xin Zeng, Francesca Zappacosta, R. Ames, 2013, Journal of biomolecular screening.

Establishment of a high-throughput screening system for universal anti-HIV targets

Shiyou Li, Yaqing Jiang, Xin Zeng, 2010 .

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

Xi He, Xin Zeng, B. Doble, 2005, Nature.

A mechanism for Wnt coreceptor activation.

Xi He, Zhijie Chang, Xin Zeng, 2004, Molecular cell.

Sonic Hedgehog as a mediator of long‐range signaling *

D. Robbins, Xin Zeng, J. Goetz, 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.

Wnt Signal Amplification via Activity, Cooperativity, and Regulation of Multiple Intracellular PPPSP Motifs in the Wnt Co-receptor LRP6*

Xi He, Xin Zeng, C. Yokota, 2008, Journal of Biological Chemistry.

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions

Chika Yokota, Xi He, Jen-Chieh Hsieh, 2007, Development.

Retinoic acid-receptor activation of SP-B gene transcription in respiratory epithelial cells.

J. Whitsett, M. Ghaffari, Xin Zeng, 1998, American journal of physiology. Lung cellular and molecular physiology.

Retinoic acid-receptor activation of SPB gene transcription in respiratory epithelial cells

J. Whitsett, M. Ghaffari, Xin Zeng, 1998 .

Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease

Pankaj Agarwal, D. Rajpal, Vinod Kumar, 2019, PloS one.

Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth

A. Harris, Wei Zhang, F. Buffa, 2016, Oncotarget.

TGFbeta2 mediates the effects of hedgehog on hypertrophic differentiation and PTHrP expression.

T. Doetschman, R. Serra, D. Robbins, 2002, Development.

RhoH plays distinct roles in T-cell migrations induced by different doses of SDF1 alpha.

B. Lim, Hong Wang, Xin Zeng, 2010, Cellular signalling.

Roles of tetrahydrobiopterin in promoting tumor angiogenesis.

D. Kerr, A. Harris, E. O’Neill, 2010, The American journal of pathology.

Roles of Tetrahydrobiopterin in Promoting Tumor

D. Kerr, A. Harris, Ji-Liang Li, 2010 .

Yeast Two-hybrid System Demonstrates That Estrogen Receptor Dimerization Is Ligand-dependent in Vivo(*)

Hong Wang, G. Peters, W. Ip, 1995, The Journal of Biological Chemistry.

Activation of nuclear factor-κB pathway is responsible for tumor necrosis factor-α-induced up-regulation of endothelin B2 receptor expression in vascular smooth muscle cells in vitro.

Hui-jie Zhang, Xue-jun Li, Xin Zeng, 2012, Toxicology letters.

Overexpression of SHCBP1 promotes migration and invasion in gliomas by activating the NF‐κB signaling pathway

Jun Yu Li, Wenjiao Wu, Xin Zeng, 2018, Molecular carcinogenesis.

A novel approach applying a chemical biology strategy in phenotypic screening reveals pathway-selective regulators of histone 3 K27 tri-methylation.

Pankaj Agarwal, Dwight M. Morrow, Q. Xie, 2014, Molecular bioSystems.

Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays

Joseph G Boyer, G. Hofmann, D. Grillot, 2018, PloS one.

Thyroid transcription factor‐1, hepatocyte nuclear factor‐3β and surfactant protein A and B in the developing chick lung

J. Whitsett, K. Yutzey, Xin Zeng, 1998, Journal of anatomy.

Estrogen receptor variants ERΔ5 and ERΔ7 down-regulate wild-type estrogen receptor activity

Hong Wang, Sohaib A. Khan, Xin Zeng, 1999, Molecular and Cellular Endocrinology.

Dimethyl Sulfoxide Decrease Type-I and -III Collagen Synthesis in Human Hepatic Stellate Cells and Human Foreskin Fibroblasts (Abstract)

Yan Deng, Chuan-ke Zhao, Shiyou Li, 2010 .

Short Article A Mechanism for Wnt Coreceptor Activation

Y. Harada, Xi He, Xin Zeng, 2004 .

A High-Content Imaging Screen for Cellular Regulators of β-Catenin Protein Abundance

Pankaj Agarwal, Dwight M. Morrow, Zining Wu, 2016, Journal of biomolecular screening.