P. Eidam

发表

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.

Michelle C. Schaeffer, Carol A. Capriotti, P. A. Harris, 2017, Journal of medicinal chemistry.

Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity.

Philip Hardwicke, John Bertin, Bryan W King, 2015, Bioorganic & medicinal chemistry.

Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway

J. Bertin, V. Kasparcova, Jong W. Yu, 2013, PloS one.

Identification of Selective Small Molecule Inhibitors of the Nucleotide-Binding Oligomerization Domain 1 (NOD1) Signaling Pathway

J. Bertin, V. Kasparcova, Zining Wu, 2014, PloS one.

The BlueScreen-384 Assay as an Indicator of Genotoxic Hazard Potential in Early-Stage Drug Discovery

S. Rees, P. Eidam, Poonam Shah, 2013, Journal of biomolecular screening.

Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.

Michelle C. Schaeffer, Carol A. Capriotti, Paul E. Lamoureux, 2019, Journal of medicinal chemistry.

Structure-activity relationship studies of novel 3-oxazolidinedione-6-naphthyl-2-pyridinones as potent and orally bioavailable EP3 receptor antagonists.

Carl A. Brooks, Dwight M. Morrow, P. Eidam, 2011, Bioorganic & medicinal chemistry letters.

Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists.

Carl A. Brooks, D. Holt, Dwight M. Morrow, 2010, ACS medicinal chemistry letters.

Palladium- and copper-catalyzed 1,4-additions of organozinc compounds to conjugated aldehydes.

M. Herold, P. Eidam, J. A. Marshall, 2006, Organic letters.

Diastereoselective Additions of Chiral Vinylzinc Reagents to α-Chiral Aldehydes

P. Eidam, J. A. Marshall, 2004 .

The Oxa-Pictet-Spengler Reaction of 1-(3-Furyl)alkan-2-ols

P. Eidam, D. Swarr, K. Gelato, 2002 .

Synthesis of 4‐Triisopropylsilyl‐3‐Butyn‐2‐ol by Asymmetric Transfer Hydrogenation

P. Eidam, J. A. Marshall, H. Eidam, 2007 .

HPTLC ANALYSIS OF TISSUE AND BLOOD OF BIOMPHALARIA GLABRATA SNAILS TO ASSESS THE EFFECTS OF A DIET OF ROMAINE LETTUCE LEAF VERSUS MIDRIB ON THE CONCENTRATIONS OF LIPIDS, PIGMENTS,AND CARBOHYDRATES

B. Fried, P. Eidam, J. Sherma, 2001 .

Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer

P. A. Harris, J. Bertin, M. Mahajan, 2019, ACS medicinal chemistry letters.

A formal synthesis of the callipeltoside aglycone.

P. Eidam, J. A. Marshall, J. Marshall, 2008, Organic letters.

(R)- and (S)-4-TIPS-3-butyn-2-ol. Useful precursors of chiral allenylzinc and indium reagents.

P. Eidam, H. Eidam, J. Marshall, 2006, The Journal of organic chemistry.