G. Yohrling

发表

Chromatin immunoprecipitation technique for study of transcriptional dysregulation in intact mouse brain.

A. Chen-Plotkin, J. Cha, Melissa W. Braveman, 2004, Methods in molecular biology.

Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models.

S. Hersch, C. Benn, J. Cha, 2007, Human molecular genetics.

Identification of substrate orienting and phosphorylation sites within tryptophan hydroxylase using homology-based molecular modeling.

K. Vrana, J. Schmitt, G. Yohrling, 2000, Journal of molecular biology.

Intersubunit binding domains within tyrosine hydroxylase and tryptophan hydroxylase

K. Vrana, S. Mockus, G. Yohrling, 2000, Journal of neuroscience research.

Enzyme Activity: Control

K. Vrana, J. Flanagan, G. Yohrling, 2007 .

Identification of amino-terminal sequences contributing to tryptophan hydroxylase tetramer formation

K. Vrana, S. Mockus, G. Yohrling, 1999, Journal of Molecular Neuroscience.

Epidemiology of Huntington’s Disease in the United States Medicare and Medicaid Populations

E. Chang, A. Exuzides, G. Yohrling, 2022, Neuroepidemiology.

Quality of Care for Huntington's Disease in the United States: Findings from a National Survey of Patients and Caregivers.

K. Anderson, G. Yohrling, A. Kinel, 2019, Journal of Huntington's disease.

A cocaine analog, 2β-propanoyl-3β-(4-tolyl)-tropane (PTT), reduces tyrosine hydroxylase in the mesolimbic dopamine pathway

J. Daunais, K. Vrana, W. Freeman, 2000 .

Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads.

M. Vandermeeren, M. Mercken, C. Ho, 2010, Bioorganic & medicinal chemistry letters.

Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation

L. Farrell, A. Hollenberg, J. Cha, 2003, Molecular and Cellular Neuroscience.

Huntingtin Modulates Transcription, Occupies Gene Promoters In Vivo, and Binds Directly to DNA in a Polyglutamine-Dependent Manner

C. Benn, J. Cha, B. Bouzou, 2008, The Journal of Neuroscience.

Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease

M. MacDonald, D. Krainc, L. Farrell, 2006, Neurobiology of Disease.

Characterization of HTT Inclusion Size, Location, and Timing in the zQ175 Mouse Model of Huntington´s Disease: An In Vivo High-Content Imaging Study

S. Kwak, A. Ebneth, G. Yohrling, 2015, PloS one.

Striatal synaptosomes from Hdh140Q/140Q knock-in mice have altered protein levels, novel sites of methionine oxidation, and excess glutamate release after stimulation.

S. Shaffer, S. Kwak, K. Green, 2013, Journal of Huntington's disease.

Mutation measurement in mammalian cells IV: Comparison of γ-ray and chemical mutagenesis

T. Puck, G. Yohrling, P. Webb, 1998 .

Healthcare utilization and cost burden of Huntington’s disease among Medicare beneficiaries in the United States

E. Chang, A. Exuzides, G. Yohrling, 2021, Journal of medical economics.

Survey of the Huntington's Disease Patient and Caregiver Community Reveals Most Impactful Symptoms and Treatment Needs.

J. Kogan, G. Yohrling, J. Simpson, 2016, Journal of Huntington's disease.

Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology.

David W. Miller, A. Young, K. Vrana, 2003, Brain research. Molecular brain research.

Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons

G. Yohrling, Boyu Zhao, D. Brenneman, 2009, Epilepsy Research.

Enzymatic Activity: Control

G. Yohrling, 2001 .

Tyrosine hydroxylase and tryptophan hydroxylase do not form heterotetramers

K. Vrana, S. Mockus, G. Yohrling, 1998, Journal of Molecular Neuroscience.