Y. Gasche

K. Schaller, F. Mach, F. Montecucco, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Acute revascularization in ischemic stroke: Updated Swiss guidelines

E. Carrera, P. Mordasini, S. Engelter, 2021 .

Overexpression of Copper and Zinc Superoxide Dismutase in Transgenic Mice Prevents the Induction and Activation of Matrix Metalloproteinases after Cold Injury-Induced Brain Trauma

M. Fujimura, P. Chan, J. Copin, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Early appearance of activated matrix metalloproteinase-9 and blood–brain barrier disruption in mice after focal cerebral ischemia and reperfusion

M. Fujimura, P. Chan, M. Kawase, 1999, Brain Research.

Protein S100 as outcome predictor after out-of-hospital cardiac arrest and targeted temperature management at 33 °C and 36 °C

M. Wise, Y. Devaux, M. Kuiper, 2017, Critical Care.

Mortality and neurological outcome in the elderly after target temperature management for out-of-hospital cardiac arrest.

M. Wise, M. Kuiper, C. Hassager, 2015, Resuscitation.

Resting-State Brain Activity for Early Prediction Outcome in Postanoxic Patients in a Coma with Indeterminate Clinical Prognosis

D. Pugin, S. Haller, S. Vulliémoz, 2020, American Journal of Neuroradiology.

No difference in mortality between men and women after out-of-hospital cardiac arrest.

M. Wise, C. Hassager, T. Cronberg, 2015, Resuscitation.

Single versus Serial Measurements of Neuron-Specific Enolase and Prediction of Poor Neurological Outcome in Persistently Unconscious Patients after Out-Of-Hospital Cardiac Arrest – A TTM-Trial Substudy

M. Wise, Y. Devaux, M. Kuiper, 2017, PloS one.

Life-threatening neuroleptic withdrawal emergent syndrome resembling status dystonicus.

P. Pollak, D. Pugin, P. Burkhard, 2017, Parkinsonism & Related Disorders.

Early Appearance of Activated Matrix Metalloproteinase-9 after Focal Cerebral Ischemia in Mice: A Possible Role in Blood—Brain Barrier Dysfunction

M. Fujimura, P. Chan, M. Kawase, 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

MATRIX METALLOPROTEINASES CORRELATE WITH ALVEOLAR-CAPILLARY PERMEABILITY ALTERATION IN LUNG ISCHEMIA-REPERFUSION INJURY

P. Suter, D. Slosman, P. Soccal, 2000, Transplantation.

Complement depletion during haemofiltration with polyacrilonitrile membranes.

J. Chevrolet, Y. Gasche, P. Suter, 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Carbohydrate source influences gelatinase production by mouse astrocytes in vitro

P. Chan, Y. Gasche, Pak H. Chan, 2002, Glia.

Matrix metalloproteinase-9 deficiency has no effect on glial scar formation after transient focal cerebral ischemia in mouse

J. Copin, Y. Gasche, 2007, Brain Research.

Overexpression of SOD1 protects vulnerable motor neurons after spinal cord injury by attenuating mitochondrial cytochrome c release

T. Sugawara, F. Yu, A. Lewén, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency.

M. Fujimura, P. Chan, M. Kawase, 1999, Stroke.

Persisting vasculitis after pneumococcal meningitis

D. Pugin, T. Landis, J. Copin, 2006, Neurocritical care.

Percutaneous Aortic Balloon Valvuloplasty and Intracardiac Adrenaline in Electromechanical Dissociation as Bridge to Transcatheter Aortic Valve Implantation

M. Roffi, P. Meier, Y. Gasche, 2015, Medicine.

Delayed matrix metalloproteinase inhibition reduces intracerebral hemorrhage after embolic stroke in rats

T. Sugawara, P. Chan, J. Copin, 2008, Experimental Neurology.

Effects of global ischemia duration on neuronal, astroglial, oligodendroglial, and microglial reactions in the vulnerable hippocampal CA1 subregion in rats.

T. Sugawara, N. Noshita, P. Chan, 2002, Journal of neurotrauma.

Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia.

A. Shah, S. Shapiro, P. Chan, 2005, American journal of physiology. Heart and circulatory physiology.

Matrix Metalloproteinase Inhibition Decreases Ischemia‐Reperfusion Injury After Lung Transplantation

G. Berry, P. Soccal, R. Robbins, 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

A low body temperature on arrival at hospital following out-of-hospital-cardiac-arrest is associated with increased mortality in the TTM-study.

M. Wise, M. Kuiper, C. Hassager, 2016, Resuscitation.

Targeted temperature management at 33°C versus 36°C after cardiac arrest.

M. Wise, L. Køber, M. Kuiper, 2013, The New England journal of medicine.

Protein S100b for outcome prediction after out-of-hospital cardiac arrest and target temperature management at 33 °C and 36 °C

Y. Devaux, M. Kuiper, C. Hassager, 2015 .

Time to start of cardiopulmonary resuscitation and the effect of target temperature management at 33°C and 36°C

C. Hassager, T. Cronberg, N. Nielsen, 2015, Intensive Care Medicine Experimental.

Fatal brain gas embolism during non-invasive positive pressure ventilation

C. J. Rivara, J. Chevrolet, E. Charbonney, 2008, BMJ Case Reports.

The prognostic significance of the serum biomarker heart-fatty acidic binding protein in comparison with s100b in severe traumatic brain injury.

B. Walder, Jean-Charles Sanchez, J. Copin, 2013, Journal of neurotrauma.

Slaughterhouse blood as a perfusate for studying myocardial function under ischemic conditions.

M. Janier, D. Revel, Y. Gasche, 2003, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Incidence and Outcome of Aneurysmal Subarachnoid Hemorrhage

C. Woernle, M. Sailer, L. Mariani, 2020, Stroke.

Response by the authors

Y. Gasche, 2006 .

Neurologic Function and Health-Related Quality of Life in Patients Following Targeted Temperature Management at 33°C vs 36°C After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.

M. Wise, M. Kuiper, C. Hassager, 2015, JAMA neurology.

Detailed statistical analysis plan for the target temperature management after out-of-hospital cardiac arrest trial

M. Wise, M. Kuiper, C. Hassager, 2013, Trials.

Matrix metalloproteinases and inflammatory diseases of the central nervous system

J. Copin, Y. Gasche, 2008 .

Overexpression of Copper/Zinc Superoxide Dismutase in Transgenic Rats Protects Vulnerable Neurons against Ischemic Damage by Blocking the Mitochondrial Pathway of Caspase Activation

T. Sugawara, M. Fujimura, N. Noshita, 2002, The Journal of Neuroscience.

Outcome and Prognostic Factors in Bacteremic Sepsis

D. Pittet, P. Suter, Y. Gasche, 1995 .

Serum profiles of interleukin-6, interleukin-8, and interleukin-10 in patients with severe and mild acute pancreatitis.

P. Morel, T. Berney, G. Grau, 1999, Pancreas.

Clinical features and viral kinetics in a rapidly cured patient with Ebola virus disease: a case report.

Tom J. Petty, E. Zdobnov, S. Yerly, 2015, The Lancet. Infectious diseases.

Successful heart transplantation after prolonged cardiac arrest and extracorporeal life support in organ donor–a case report

Raphaël Giraud, Karim Bendjelid, Diego Arroyo, 2015, Journal of Cardiothoracic Surgery.

Treatment with Evasin-3 Reduces Atherosclerotic Vulnerability for Ischemic Stroke, but Not Brain Injury in Mice

K. Schaller, N. Stergiopulos, F. Mach, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Target Temperature Management after out-of-hospital cardiac arrest--a randomized, parallel-group, assessor-blinded clinical trial--rationale and design.

M. Kuiper, P. Pelosi, C. Hassager, 2012, American heart journal.

Type IV Collagenases and Blood-Brain Barrier Breakdown in Brain Ischemia

P. Chan, J. Copin, Y. Gasche, 2003 .

The role of metalloproteinases on blood-brain barrier breakdown after ischemic stroke

P. Chan, J. Copin, Y. Gasche, 2001 .

Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice

A. Shah, J. Gidday, J. Copin, 2005, The European journal of neuroscience.

Matrix metalloproteinase 9 and cellular fibronectin plasma concentrations are predictors of the composite endpoint of length of stay and death in the intensive care unit after severe traumatic brain injury

K. Schaller, B. Walder, Jean-Charles Sanchez, 2012, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

IVOX in ARDS: respiratory effects and serious complications.

Y. Gasche, R. Prêtre, J. Romand, 1994, The European respiratory journal.

Matrix Metalloproteinase Inhibition Prevents Oxidative Stress-Associated Blood–Brain Barrier Disruption after Transient Focal Cerebral Ischemia

Taku Sugawara, Miki Fujimura, T. Sugawara, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Target temperature management of 33°C and 36°C in patients with out-of-hospital cardiac arrest with initial non-shockable rhythm - a TTM sub-study.

M. Wise, M. Kuiper, C. Hassager, 2015, Resuscitation.

Imaging Compatible Electrodes for Continuous Electroencephalogram Monitoring in the Intensive Care Unit

Stephen Perrig, Margitta Seeck, John R. Ives, 2009, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

Oxidative Cellular Damage and the Reduction of APE/Ref-1 Expression after Experimental Traumatic Brain Injury

T. Sugawara, M. Fujimura, P. Chan, 2001, Neurobiology of Disease.

Standardized EEG interpretation accurately predicts prognosis after cardiac arrest

M. Wise, M. Kuiper, C. Hassager, 2016, Neurology.

Two structurally different T‐type Ca2+ channel inhibitors, mibefradil and pimozide, protect CA1 neurons from delayed death after global ischemia in rats

Y. Daali, B. Schatlo, P. Bijlenga, 2011, Fundamental & clinical pharmacology.

CRTC2 polymorphism as a risk factor for the incidence of metabolic syndrome in patients with solid organ transplantation

Z. Kutalik, F. Ruschitzka, C. Lovis, 2015, The Pharmacogenomics Journal.

Survival in patients without acute ST elevation after cardiac arrest and association with early coronary angiography: a post hoc analysis from the TTM trial

C. Hassager, T. Cronberg, N. Nielsen, 2015, Intensive Care Medicine.

Neuron-Speci fi c Enolase as a Predictor of Death or Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest and Targeted Temperature Management at 33 C and 36 C

M. Wise, Y. Devaux, M. Kuiper, 2015 .

Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest – an analysis of the TTM trial data

M. Wise, M. Kuiper, C. Hassager, 2016, Critical Care.

Predictive value of interleukin-6 in post-cardiac arrest patients treated with targeted temperature management at 33 °C or 36 °C.

M. Wise, Y. Devaux, M. Kuiper, 2016, Resuscitation.

Impact of time to return of spontaneous circulation on neuroprotective effect of targeted temperature management at 33 or 36 degrees in comatose survivors of out-of hospital cardiac arrest.

M. Wise, M. Kuiper, C. Hassager, 2015, Resuscitation.

Matrix metalloproteinases and diseases of the central nervous system with a special emphasis on ischemic brain.

P. Soccal, J. Copin, Y. Gasche, 2006, Frontiers in bioscience : a journal and virtual library.

Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke

F. Montecucco, J. Copin, Y. Gasche, 2014, Thrombosis and Haemostasis.

Differential reactivity of brain microvascular endothelial cells to TNF reflects the genetic susceptibility to cerebral malaria

P. Morel, W. Buurman, G. Grau, 1998, European journal of immunology.

Identifying Risk Factors for Central Pontine and Extrapontine Myelinolysis After Liver Transplantation: A Case–Control Study

N. Kneteman, G. Mentha, Y. Gasche, 2014, Neurocritical Care.

Is tracheostomy still an option in amyotrophic lateral sclerosis? Reflections of a multidisciplinary work group.

I. Leuchter, M. Escher, J. Janssens, 2013, Swiss medical weekly.

Pancreatic stone protein as a biomarker for the early diagnosis of post-operative peritonitis, intra-abdominal infection and sepsis

D. Pugin, Y. Gasche, Frédéric Mollard, 2022, Journal of surgical case reports.

Usefulness of Serum B-Type Natriuretic Peptide Levels in Comatose Patients Resuscitated from Out-of-Hospital Cardiac Arrest to Predict Outcome.

M. Wise, Y. Devaux, M. Kuiper, 2016, The American journal of cardiology.

Decompressive Craniectomy for Space Occupying Hemispheric and Cerebellar Ischemic Strokes: Swiss Recommendations

J. Fandino, S. Engelter, H. Mattle, 2009, International journal of stroke : official journal of the International Stroke Society.

Effect of hypotension severity on hippocampal CA1 neurons in a rat global ischemia model

T. Sugawara, M. Fujimura, N. Noshita, 2000, Brain Research.

Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit

K. Schaller, J. Badaut, J. Copin, 2012, Journal of Neuroinflammation.

Infectious complications after out-of-hospital cardiac arrest-A comparison between two target temperatures.

M. Wise, M. Kuiper, C. Hassager, 2017, Resuscitation.

A Qualitative Pilot Study on Donation After Cardiac Death (DCD): Feelings Experienced by the Nursing and Medical Staff in the Adult Intensive Care Unit (ICU) of the Geneva University Hospitals

C. Cedraschi, Y. Gasche, A. Zellweger, 2017 .

[Adverse effects of proton pump inhibitors: should we worry about long-term exposure?].

J. Desmeules, Y. Gasche, N. Vernaz, 2012, La Revue de medecine interne.

Improvement of drug-induced chronic renal failure in lung transplantation.

P. Soccal, Y. Gasche, L. Nicod, 1999, Transplantation.

Time to start of cardiopulmonary resuscitation and the effect of target temperature management at 33°C and 36°C.

M. Wise, C. Hassager, T. Cronberg, 2016, Resuscitation.

Matrix metalloproteinases and diseases of the central nervous system with a special emphasis on ischemic brain GASCHE

P. Soccal, J. Copin, Y. Gasche, 2018 .

Standardized EEG interpretation accurately predicts prognosis after cardiac arrest

M. Wise, M. Kuiper, C. Hassager, 2016, Neurology.

Complement depletion during haemofiltration with polyacrilonitrile membranes.

J. Chevrolet, J. Schifferli, Y. Gasche, 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[Adverse effects of proton pump inhibitors: should we worry about long-term exposure?].

J. Desmeules, Y. Gasche, N. Vernaz, 2012, La Revue de medecine interne.

Is tracheostomy still an option in amyotrophic lateral sclerosis? Reflections of a multidisciplinary work group

I. Leuchter, M. Escher, J. Janssens, 2013, Journal of the Neurological Sciences.

Target Temperature Management after out-of-hospital cardiac arrest--a randomized, parallel-group, assessor-blinded clinical trial--rationale and design.

M. Kuiper, P. Pelosi, C. Hassager, 2012, American heart journal.

Matrix metalloproteinases and inflammatory diseases of the central nervous system

J. Copin, Y. Gasche, 2008 .

Neuron-Specific Enolase as a Predictor of Death or Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest and Targeted Temperature Management at 33°C and 36°C.

M. Wise, Y. Devaux, M. Kuiper, 2015, Journal of the American College of Cardiology.