C. Murphy

发表

Development of a bacterial propionate-biosensor for anaerobic digestion monitoring.

K. McDonnell, Joseph Sweeney, C. Murphy, 2018, Enzyme and microbial technology.

A 19F NMR study of fluorobenzoate biodegradation by Sphingomonas sp. HB-1.

W. C. Mcroberts, C. Murphy, F. Boersma, 2004, FEMS microbiology letters.

Bacterial production of hydroxylated and amidated metabolites of flurbiprofen

C. Murphy, B. Clark, Tara Bright, 2011 .

Production of the novel lipopeptide antibiotic trifluorosurfactin via precursor-directed biosynthesis

D. Rai, C. Murphy, B. Clark, 2012 .

Cunninghamella spp. produce mammalian-equivalent metabolites from fluorinated pyrethroid pesticides

M. F. Khan, C. Murphy, 2021, AMB Express.

Simultaneous removal of malachite green and hexavalent chromium by Cunninghamella elegans biofilm in a semi-continuous system

S. Hussain, C. Murphy, E. Casey, 2017 .

Understanding the mechanisms of biofouling on nanofiltration membranes: Effect of the biofilm structure on solute removal

C. Murphy, E. Casey, A. J. Semiao, 2012 .

Exploiting the genome sequence of Streptomyces nodosus for enhanced antibiotic production

P. Caffrey, C. Murphy, P. Sweeney, 2015, Applied Microbiology and Biotechnology.

Drug metabolism in microorganisms

C. Murphy, 2014, Biotechnology Letters.

Biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya. Incorporation of oxygen-18 from [2-2H,2-18O]-glycerol and the role of serine metabolites in fluoroacetaldehyde biosynthesis

J. Hamilton, C. Murphy, D. O'Hagan, 2001 .

A REVIEW New frontiers in biological halogenation

C. Murphy, 2003 .

New frontiers in biological halogenation.

C. Murphy, 2003, Journal of applied microbiology.

Strategies for Biodegradation of Fluorinated Compounds

I. Moreira, P. Castro, C. Murphy, 2018 .

Treatment of fluoroacetate by a Pseudomonas fluorescens bioflm grown in membrane aerated biofilm reactor.

C. Murphy, E. Casey, B. Heffernan, 2009, Environmental science & technology.

Treatment of fluoroacetate by a Pseudomonas fluorescens bioflm grown in membrane aerated biofilm reactor.

C. Murphy, E. Casey, B. Heffernan, 2009, Environmental science & technology.

Biotransformation of fluorobiphenyl by Cunninghamella elegans

C. Murphy, Jessica Amadio, 2010, Applied Microbiology and Biotechnology.

Evaluation of fluorinated biphenyl ether pro-drug scaffolds employing the chemical-microbial approach.

G. Sandford, C. Murphy, A. Hampton, 2016, Bioorganic & medicinal chemistry letters.

Production of drug metabolites by immobilised Cunninghamella elegans: from screening to scale up

C. Murphy, E. Casey, Laura Quinn, 2015, Journal of Industrial Microbiology & Biotechnology.

Production of human metabolites of the anti-cancer drug flutamide via biotransformation in Cunninghamella species

C. Murphy, Jessica Amadio, 2011, Biotechnology Letters.

An isotopic labeling method for determining production of volatile organohalogens by marine microalgae

C. Murphy, R. Moore, R. L. White, 2000 .

Metabolism and hydrophilicity of the polarised ‘Janus face’ all-cis tetrafluorocyclohexyl ring, a candidate motif for drug discovery† †Electronic supplementary information (ESI) available. CCDC 1817386–1817390. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8sc

A. Slawin, C. Murphy, D. O'Hagan, 2018, Chemical science.

Recent advances in fluorination techniques and their anticipated impact on drug metabolism and toxicity

G. Sandford, C. Murphy, 2015, Expert opinion on drug metabolism & toxicology.

Targeted Fluorination of a Nonsteroidal Anti‐inflammatory Drug to Prolong Metabolic Half‐Life

G. Sandford, C. Murphy, Tara Bright, 2014, ChemMedChem.

Factors influencing 4-fluorobenzoate degradation in biofilm cultures of Pseudomonas knackmussii B13.

C. Murphy, E. Casey, Katarzyna Misiak, 2011, Water research.

Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenes KF707.

C. Murphy, Shane Quirke, O. Balogun, 2008, FEMS microbiology letters.

Isolation of an Aldehyde Dehydrogenase Involved in the Oxidation of Fluoroacetaldehyde to Fluoroacetate inStreptomyces cattleya

S. Moss, C. Murphy, D. O'Hagan, 2001, Applied and Environmental Microbiology.

Biosynthesis of 2-aminooctanoic acid and its use to terminally modify a lactoferricin B peptide derivative for improved antimicrobial activity

K. O’Connor, T. Narancic, S. Kenny, 2017, Applied Microbiology and Biotechnology.

19F NMR as a tool in chemical biology

C. Murphy, S. Cobb, A. Phelan, 2021, Beilstein journal of organic chemistry.

Metabolism of fluoroorganic compounds in microorganisms: impacts for the environment and the production of fine chemicals

C. Murphy, B. Clark, Jessica Amadio, 2009, Applied Microbiology and Biotechnology.

Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp.

Stephen J. Moran, D. Rai, C. Murphy, 2009, Organic & biomolecular chemistry.

Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis inStreptomyces cattleya

C. Murphy, D. O'Hagan, Christoph Schaffrath, 2001 .

Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis in Streptomyces cattleya This work was supported by the Biotechnological and Biological Sciences Research Council and the University of St Andrews.

C. Murphy, D. O'Hagan, Christoph Schaffrath, 2001, Angewandte Chemie.

Biocatalytic stereoinversion of D-para-bromophenylalanine in a one-pot three-enzyme reaction

P. Engel, F. Khorsand, A. J. Whitehead, 2017 .

CS 93 via precursor-directed biosynthesis

Robertson, C. Murphy, S. Cobb, 2018 .

Novel fluorinated lipopeptides from Bacillus sp. CS93 via precursor-directed biosynthesis

C. Murphy, S. Cobb, Vanessa M S Duncan, 2014, Amino Acids.

Running title: Performance of P. fluorescens grown on fluoroacetate

C. Murphy, E. Casey, B. Heffernan, 2009 .

Fluorotelomer alcohols are efficiently biotransformed by Cunninghamella elegans

M. F. Khan, C. Murphy, 2022, Environmental Science and Pollution Research.

Bacterial defluorination of 4-fluoroglutamic acid

C. Murphy, C. Donnelly, 2007, Applied Microbiology and Biotechnology.

Towards an effective biosensor for monitoring AD leachate: a knockout E. coli mutant that cannot catabolise lactate

K. McDonnell, C. Murphy, Joseph B. Sweeney, 2015, Applied Microbiology and Biotechnology.

Comparison of biomass detachment from biofilms of two different Pseudomonas spp. under constant shear conditions

C. Murphy, E. Casey, O. Habimana, 2015, Biofouling.

Comparison of biomass detachment from two different Pseudomonas spp. biofilms under constant shear conditions

Eoin Casey, C. Murphy, O. Habimana, 2022 .

Coprostanol as a Population Biomarker for SARS-CoV-2 Wastewater Surveillance Studies

W. Meijer, M. F. Khan, N. Fletcher, 2022, Water.

Production of lipopeptides in Bacillus sp. CS93 isolated from Pozol.

Stephen J. Moran, D. Rai, F. Paradisi, 2010, FEMS microbiology letters.

Identification and characterisation of a Streptomyces sp. isolate exhibiting activity against methicillin-resistant Staphylococcus aureus.

C. Murphy, S. Higginbotham, 2010, Microbiological research.

Recent developments in enzymatic chlorination.

C. Murphy, 2006, Natural product reports.

Halogenated Organic Compounds – Carbon-Halogen Bond Formation

C. Murphy, 2010 .

Peroxidases from marine microalgae

Robert L. White, C. Murphy, R. Moore, 2000, Journal of Applied Phycology.

3-Hydroxytyrosol regulates biofilm growth in Cunninghamella elegans.

M. F. Khan, C. Murphy, 2020, Fungal biology.

Chemical Production: Biohalogenation

C. Murphy, 2016 .

Biochemistry: Biosynthesis of an organofluorine molecule

J. Hamilton, C. Murphy, D. O'Hagan, 2002, Nature.

Fluoroacetaldehyde: a precursor of both fluoroacetateand 4-fluorothreonine in Streptomyces cattleya

W. C. Mcroberts, J. Hamilton, S. Moss, 2000 .

Cyhalothrin biodegradation in Cunninghamella elegans

C. Murphy, William Palmer-Brown, Paula L de Melo Souza, 2018, Environmental Science and Pollution Research.

Biodegradation and biotransformation of organofluorine compounds

C. Murphy, 2010, Biotechnology Letters.

Regulation of Cunninghamella spp. biofilm growth by tryptophol and tyrosol

M. F. Khan, C. Murphy, D. Saleem, 2021, Biofilm.

The CYPome of the model xenobiotic-biotransforming fungus Cunninghamella elegans

Kevin P. Byrne, K. H. Wolfe, C. Murphy, 2019, Scientific Reports.

Filamentous fungal biofilm for production of human drug metabolites

C. Murphy, E. Casey, Jessica Amadio, 2013, Applied Microbiology and Biotechnology.

Biotransformation of Flurbiprofen by Cunninghamella Species

C. Murphy, Jessica Amadio, K. Gordon, 2010, Applied and Environmental Microbiology.

Production of anticancer polyenes through precursor-directed biosynthesis.

S. O'connor, C. Murphy, B. Clark, 2011, Organic & biomolecular chemistry.

Structures and biosynthesis of the pyridinopyrones, polyenepyrones from a marine-derived Streptomyces species.

P. Jensen, C. Murphy, W. Fenical, 2011, Journal of natural products.

Biosynthesis of pyrrolylpolyenes in Auxarthron umbrinum.

C. Murphy, B. Clark, 2009, Organic & biomolecular chemistry.

Microbial biotransformation of aryl sulfanylpentafluorides

C. Murphy, M. Winn, P. Beier, 2013, Environmental Science and Pollution Research.

New insights into polyene macrolide biosynthesis in Couchioplanes caeruleus.

P. Caffrey, C. Murphy, J. Sheehan, 2017, Molecular bioSystems.

A short highly stereoselective synthesis of the fluorinated natural product (2S,3S)-4-fluorothreonine

J. Howard, C. Murphy, D. O'Hagan, 1997 .

The synthesis and biological testing of bacilysin analogues

F. Paradisi, C. Murphy, K. Robertson, 2013, Amino Acids.

Bacterial degradation of the anti-depressant drug fluoxetine produces trifluoroacetic acid and fluoride ion

M. F. Khan, C. Murphy, 2021, Applied Microbiology and Biotechnology.

Antitumor Activity of the Cyclo (L-Phenyl, L-Prolyl) Diketopiperazines Produced By a Newly Isolated Streptomyces Sp. A4.4

C. Murphy, B. Clark, A. Hamza, 2018 .

Biodegradation of polyfluorinated biphenyl in bacteria

C. Murphy, B. Clark, D. Hughes, 2011, Biodegradation.

19F NMR applications in chemical biology

C. Murphy, S. Cobb, 2009 .

The application of 19F nuclear magnetic resonance to investigate microbial biotransformations of organofluorine compounds.

C. Murphy, 2007, Omics : a journal of integrative biology.

Biodegradation of pentafluorosulfanyl-substituted aminophenol in Pseudomonas spp.

R. Konrat, S. Hussain, C. Murphy, 2018, Biodegradation.

Influence of attached growth on the performance of Pseudomonas fluorescens grown on fluoroacetate as the sole organic substrate Running title: Influence of attached growth on P. fluorescens

C. Murphy, E. Casey, B. Heffernan, 2017 .

Comparison of Planktonic and Biofilm Cultures of Pseudomonas fluorescens DSM 8341 Cells Grown on Fluoroacetate

Eoin Casey, C. Murphy, B. Heffernan, 2009, Applied and Environmental Microbiology.

Purification and properties of fluoroacetate dehalogenase from Pseudomonas fluorescens DSM 8341

C. Murphy, C. Donnelly, 2009, Biotechnology Letters.

The Application of 19F Nuclear Magnetic Resonance to Investigate Microbial Biotransformations of Organofluorine Compounds

C. Murphy, 2008 .

Exploring the biosynthetic origin of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya

J. Hamilton, C. Murphy, D. O'Hagan, 1998 .

Engineering microorganisms to generate fluorinated platform chemicals

C. Murphy, 2021, Chem Catalysis.

Microbial metabolism of fluorinated drugs

C. Murphy, Laura Quinn, William Palmer-Brown, 2019, Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals.

Microbial degradation of fluorinated drugs: biochemical pathways, impacts on the environment and potential applications

C. Murphy, 2016, Applied Microbiology and Biotechnology.

Fluorophenol oxidation by a fungal chloroperoxidase

C. Murphy, 2006, Biotechnology Letters.

Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya.

C. Murphy, D. O'Hagan, Christoph Schaffrath, 2003, Chemosphere.

Fluorinated Natural Products: Occurrence and Biosynthesis

C. Murphy, D. O'Hagan, D. B. Harper, 2003 .

Drug metabolism in microorganisms

C. Murphy, 2014, Biotechnology Letters.

Biotransformation of fluorophenyl pyridine carboxylic acids by the model fungus Cunninghamella elegans

M. A. Fox, G. Sandford, C. Murphy, 2017, Xenobiotica; the fate of foreign compounds in biological systems.

A convenient chemical-microbial method for developing fluorinated pharmaceuticals.

G. Sandford, C. Murphy, Tara Bright, 2013, Organic & biomolecular chemistry.

Nitroreduction of flutamide by Cunninghamella elegans NADPH: Cytochrome P450 reductase

M. F. Khan, C. Murphy, 2022, Biochemistry and biophysics reports.

Understanding the physiological roles of polyhydroxybutyrate (PHB) in Rhodospirillum rubrum S1 under aerobic chemoheterotrophic conditions

G. Cagney, K. O’Connor, T. Narancic, 2016, Applied Microbiology and Biotechnology.

Phytochemicals from Algae

A. Mostaert, S. Ramaswamy, D. Carrier, 2012 .

Characteristics of Streptomyces griseus biofilms in continuous flow tubular reactors.

C. Murphy, M. Winn, E. Casey, 2014, FEMS microbiology letters.

The microbial cell factory.

C. Murphy, 2012, Organic & biomolecular chemistry.

Optimization of fermentation conditions for actinomycin D production by a newly isolated Streptomyces sp . AH 11 . 4

C. Murphy, B. Clark, Hiba A. Ali, 2013 .

Biosynthetic Origin of [R-(Z)]-4-Amino-3-chloro-2-pentenedioic Acid in Streptomyces viridogenes

C. Murphy, R. Grant, Robin I Hutchinson, 2006, Bioscience, biotechnology, and biochemistry.

Novel fluorinated lipopeptides from Bacillus sp. CS93 via precursor-directed biosynthesis

C. Murphy, S. Cobb, D. O'Neil, 2014, Amino Acids.

The CYPome of the model xenobiotic-biotransforming fungus Cunninghamella elegans

Kevin P. Byrne, K. H. Wolfe, C. Murphy, 2019, Scientific Reports.

BIOSYNTHESIS OF FLUOROACETATE AND 4-FLUOROTHREONINE BY STREPTOMYCES CATTLEYA. THE STEREOCHEMICAL PROCESSING OF GLYCEROL

J. Hamilton, C. Murphy, J. Nieschalk, 1997 .

Alternative Mild Route to the Synthesis of 4-Methylenecyclohex-2-enone, a Key Moiety of the Anticancer Compounds Ottelione A and B

F. Paradisi, C. Murphy, E. Lestini, 2012 .

Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds

M. F. Khan, B. Koksch, C. Murphy, 2023, Environmental science & technology.

Population dynamics of a dual Pseudomonas putida–Pseudomonas fluorescens biofilm in a capillary bioreactor

C. Murphy, O. Habimana, Laura Quinn, 2019, Biofouling.

Isolation and characterisation of actinomycin D producing Streptomyces spp. from Sudanese soil

C. Murphy, B. Clark, Hiba A. Ali, 2013 .

Aryl (β,β′,β″-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives

Rodrigo A. Cormanich, C. Murphy, C. Isanbor, 2023, Organic letters.

Microbial degradation of fluorinated drugs: biochemical pathways, impacts on the environment and potential applications

C. Murphy, 2016, Applied Microbiology and Biotechnology.

Targeted Fluorination of a Nonsteroidal Anti‐inflammatory Drug to Prolong Metabolic Half‐Life

G. Sandford, C. Murphy, Tara Bright, 2014, ChemMedChem.

A convenient chemical-microbial method for developing fluorinated pharmaceuticals.

G. Sandford, C. Murphy, Tara Bright, 2013, Organic & biomolecular chemistry.

Treatment of fluoroacetate by a Pseudomonas fluorescens bioflm grown in membrane aerated biofilm reactor.

C. Murphy, B. Heffernan, E. Syron, 2009, Environmental Science and Technology.

Biodegradation of pentafluorosulfanyl-substituted aminophenol in Pseudomonas spp.

R. Konrat, S. Hussain, C. Murphy, 2018, Biodegradation.

Cytochrome P450 5208A3 is a promiscuous xenobiotic biotransforming enzyme in Cunninghamella elegans.

M. F. Khan, C. Murphy, 2022, Enzyme and microbial technology.

Recent advances in fungal xenobiotic metabolism: enzymes and applications

M. F. Khan, C. Murphy, Carina Hof, 2023, World Journal of Microbiology and Biotechnology.

The microbial cell factory.

C. Murphy, 2012, Organic & biomolecular chemistry.

Fengycin A Analogues with Enhanced Chemical Stability and Antifungal Properties

C. Murphy, S. Cobb, A. Phelan, 2021, Organic letters.

Biosynthesis of 2-aminooctanoic acid and its use to terminally modify a lactoferricin B peptide derivative for improved antimicrobial activity

K. O’Connor, T. Narancic, M. Devocelle, 2017, Applied Microbiology and Biotechnology.